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Uji Toksisitas Fraksi N-Heksan dan Etanol, Ekstrak Daun Dendrophthoe glabrescen (Benalu Jeruk) sebagai Skrining Awal Anti-Kanker dengan Metode Brine Shrimp Lethality Test (BSLT) Slamet Slamet; Laula Laula; Milatun Khanifah
Prosiding University Research Colloquium Proceeding of The 11th University Research Colloquium 2020: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Benalu jeruk (Dendrophthoe glabrescen) merupakan salah satu tanaman obat tradisional di Indonesia yang digunakan sebagai anti-kanker. Pemakaian setiap bahan memiliki potensi bersifat toksik tergantung dosisnya dalam tubuh sehingga perlu dilakukan skrining awal anti-kanker. Tujuan penelitian ini adalah untuk mengetahui potensi toksisitas pada ekstrak etanol, fraksi n-heksan dan fraksi etanol daun benalu jeruk dengan menggunakan metode Brine Shrimp Lethality Test (BSLT). Metode penelitian ini adalah eksperimental post test-only control group design. Digunakan 800 ekor larva Artemia salina Leach. yang berumur 48 jam dan dibagi dalam 6 kelompok dengan 5 kali replikasi. Data diperoleh dari menghitung jumlah larva yang mati 24 jam setelah perlakuan. Dilakukan analisis probit menggunakan program aplikasi komputer untuk memperoleh nilai LC50 (Lethal Concentration 50%). Hasil penelitian menunjukkan bahwa nilai LC50 ekstrak 31,67μg/mL, fraksi n-heksan 6,19μg/mL dan fraksi etanol 9,93μg/mL. Simpulan dari penelitian ini adalah dari ketiga sampel yang diuji memiliki efek toksik dengan nilai LC50< 1000 μg/mL dan yang memiliki efek toksisitas tertinggi adalah fraksi n-heksan daun benalu jeruk (Dendrophthoe glabrescen). Sehingga perlu dilakukan penelitian lebih lanjut sebagai anti-kanker.
Assistance Of Pregnant Mothers In Preparation For Labor Milatun Khanifah
Prosiding University Research Colloquium Proceeding of The 15th University Research Colloquium 2022: Bidang Pengabdian Masyarakat
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Indonesia is ranked first with the highest maternal mortality rate (AKI) of 181 countries. The main causes of maternal death in Indonesia are bleeding (28%), eclampsia (13%), and complications of abortion (11%), sepsis (10%) and prolonged labor (9%). The cause can actually be prevented by adequate pregnancy checks. One effort that encourages behavior change and provides pregnant women with the knowledge and provision of physical training to prepare for labor during Trimester III. The methods used in community service are lectures, question and answer discussions, examination of pregnant women, demonstrations of pregnancy exercises, especially pelvic rocking movements. The six-month activity is carried out in the laboratories of the UMPP DIII Midwifery Study Program and Puskesmas Hall Kedungwuni II, Pekalongan Regency. The results of activities went smoothly including antenatal care examinations, trimester III pregnancy discomfort counseling, pregnancy danger signs, childbirth preparation, physical exercises including pelvic rooking, breathing exercises and trimester III pregnancy exercises. Participants showed high enthusiasm in asking and following physical exercise movements in pregnancy.
Pengaruh Intervensi Susu Kedelai yang Difortifikasi Bubuk Daun Kelor terhadap Peningkatan Status Gizi Balita: Effect of Intervention of Soy Milk Fortified with Moringa Leaf Powder on Improving Nutritional Status Nur Chabibah; Milatun Khanifah; Pujiati Setyaningsih
Amerta Nutrition Vol. 7 No. 2 (2023): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i2.2023.210-216

Abstract

Background: Wasting and stunting status in children impacts growth and development. One of these efforts is providing supplementary food and local food-based recovery with regional specialties. The local plants can be fortified with food additives. Objective: To determine the effectiveness of fortification of Moringa leaf powder in soy milk to improve the nutritional status of children under five. Methods: The research design used a quasi-experimental design with a pre-test and post-test control design group approach. This study used total sampling with 15 children under five in the intervention and control groups. The intervention provided was education with toddler nutrition booklets and the provision of 100 CCs of soy milk that had been fortified with 0.32 mg. It was given for two consecutive months with a frequency of three to four times weekly. The control group was given education and nutrition booklets for toddlers. Results: The results of this study showed that there was a significant difference between the mean difference in body weight (BB) in the intervention group and the control group (p-value: 0.001 CI: -0.911-(-0.245)). However, the difference in mean height (TB) in the intervention group and the control group showed no significant difference (p-value; 0.157; CI 2.244 – 0.38)). There was a significant increase in nutritional status in the intervention group (p-value: 0,009 CI: (-1.159 – (-0.174) Conclusion: Fortification of Moringa powder in soy milk can increase the weight of toddlers with poor nutritional status.
Pengetahuan Ibu Hamil yang Mengikuti Kelas Ibu Hamil Tentang Manajemen Nyeri Persalinan Non Farmakologi Winarti Susi Susanti; Risqi Dewi Aisyah; Milatun Khanifah
Jurnal Ilmiah Kesehatan Vol. 6 No. 1 (2014): Jurnal ILMU KESEHATAN (JIK)
Publisher : Universitas Muhammadiyah Pekajangan Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48144/jiks.v6i1.22

Abstract

Persalinan seksio sesarea diseluruh dunia meningkat dengan pesat, sedangkan angka di Indonesia belum diketahui secara pasti. Dulu persalinan seksio sesarea dilakukan atas indikasi adanya komplikasi persalinan, sekarang banyak ibu memilih seksio sesarea untuk mendapatkan tanggal lahir yang cantik maupun untuk menghindari nyeri persalinan. Nyeri persalinan yang tidak ditangani mengakhibatkan nyeri semakin berat, takut, dan kecemasan yang memicu timbulnya stres, trauma dan persalinan lama. Pengetahuan ibu hamil yang baik mengenai manajemen nyeri persalinan mempengaruhi sikap ibu, menghasilkan perilaku positif untuk mengatasi nyeri persalinan dan menikmati secara alami proses persalinan. Tujuan penelitian ini untuk mengetahui gambaran pengetahuan ibu hamil yang mengikuti kelas ibu hamil tentang manajemen nyeri persalinan non farmakologi. Desain penelitian bersifat deskriptif. Populasi dalam penelitian ini adalah ibu hamil yang mengikuti kelas ibu hamil di wilayah kerja Puskesmas Jenggot Kota Pekalongan dengan sampel sejumlah 43 responden. Metode pengumpulan data yang digunakan adalah angket. Hasil penelitian menunjukkan ibu hamil yang mengikuti kelas ibu hamil lebih dari separuh (55,8%) berpengetahuan cukup mengenai manajemen nyeri non farmakologi. Saran bagi tenaga kesehatan hendaknya dalam mengadakan kelas ibu hamil tidak hanya tiga kali pertemuan, dan materi yang diberikan juga tidak terlalu banyak sehingga ibu hamil dapat menerima dan memahami materi yang diberikan.
FACTOR ANALYSIS OF INTRANATAL AND POSTNATAL TOWARD STUNTING Nur Chabibah; Rini Kristiyanti; Milatun Khanifah
Siklus : Journal Research Midwifery Politeknik Tegal Vol 10, No 1 (2021)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/siklus.v10i1.2139

Abstract

Multidimensional factors caused stunting and intervention, mostly focusing on the first 1000 days of life. Maternal factors consist of prenatal, intranatal, and postnatal factors. The purpose of this study was to determine the intranatal and postnatal factors influencing the incidence of stunting. The design of this research was descriptive-analytic with a retrospectives approach. This study's population was children aged 1-3 years old using random cluster sampling and obtained 35 respondents as case group and 35 respondents as the control group. This study shows that there were variables associated with stunting such as labour history with odds ratio 0.103 (p-value: 0.001; 95% CI: 0.030-0.350) and basic immunization history with odds ratio 5.785 (p-value: 0.022; 95% CI: 1.285-26.028). Based on the finding, comprehensive health care is needed in preventing stunting Keyword: Stunting, Intranatal, Postnatal, Labor history, Basic immunization history
FACTOR ANALYSIS OF INTRANATAL AND POSTNATAL TOWARD STUNTING Nur Chabibah; Rini Kristiyanti; Milatun Khanifah
Siklus : Journal Research Midwifery Politeknik Tegal Vol 10, No 1 (2021)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/siklus.v10i1.2139

Abstract

Multidimensional factors caused stunting and intervention, mostly focusing on the first 1000 days of life. Maternal factors consist of prenatal, intranatal, and postnatal factors. The purpose of this study was to determine the intranatal and postnatal factors influencing the incidence of stunting. The design of this research was descriptive-analytic with a retrospectives approach. This study's population was children aged 1-3 years old using random cluster sampling and obtained 35 respondents as case group and 35 respondents as the control group. This study shows that there were variables associated with stunting such as labour history with odds ratio 0.103 (p-value: 0.001; 95% CI: 0.030-0.350) and basic immunization history with odds ratio 5.785 (p-value: 0.022; 95% CI: 1.285-26.028). Based on the finding, comprehensive health care is needed in preventing stunting Keyword: Stunting, Intranatal, Postnatal, Labor history, Basic immunization history
LAYANAN KESEHATAN IBU HAMIL BERKSEINAMBUNGAN Nur Chabibah; Milatun Khanifah
GEMASSIKA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 1 (2019): MEI
Publisher : P3M Universitas Aisyiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30787/gemassika.v3i1.382

Abstract

Kehamilan adalah masa ketika ada berbagai perubahan. Perubahan-perubahan ini dapat terjadi secara fisiologis, tetapi mereka juga dapat menjadi potologis. Oleh karena itu, identifikasi faktor risiko selama kehamilan dan layanan berkelanjutan memainkan peran penting dalam mengurangi angka kematian ibu. Salah satu bentuk kerja sama lintas sektoral dari sektor pendidikan dan kesehatan adalah menjadi fasilitator yang diharapkan dapat mendorong agen perubahan dalam masyarakat, terutama dalam mengurangi angka kematian ibu. Tujuan: Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan pemeriksaan dan pendidikan bagi wanita hamil tentang faktor risiko selama kehamilan dan persiapan persalinan untuk keberhasilan pemberian ASI eksklusif. Sasaran kegiatan adalah ibu hamil di Desa Pangkah Karangdadap Kecamatan Pekalongan. Manfaat yang diharapkan dari kegiatan ini adalah meningkatkan pengetahuan ibu hamil, terutama tentang faktor risiko dan persiapan persalinan untuk pemberian ASI eksklusif. Metode: Yang digunakan dalam kegiatan ini adalah pemeriksaan laboratorium, ceramah, dan diskusi. Pembicara dalam kegiatan ini adalah tim dosen STIKES Muhammadiyah Pekajangan dan Bidan di Desa Pangkah. Hasil: Kegiatan menunjukkan peserta aktif dalam kegiatan dan peningkatan pengetahuan tentang persiapan persalinan dan menyusui eksklusif
ANALISIS ASUPAN ZAT GIZI BATITA BERDASARKAN TINGKAT PENDIDIKAN, STATUS BEKERJA DAN PENGETAHUAN IBU chabibah, Nur; Khanifah, Milatun; Kristiyanti, Rini
JURNAL RISET GIZI Vol 9, No 1 (2021): Mei (2021)
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrg.v9i1.6372

Abstract

Background: Acute malnutrition could increase mortality and morbidity indirectly in infants and toddlers. The family socio-economic characteristics including the maternal education, nutritional knowledge, and family income, are related to the incidence of stunting.Objective: To determine the relationship between maternal education, working status and knowledge on dietary intake among toddlers under 3 years old.Methods: A correlative analytic study with cross-sectional design. The populations were mothers with toddlers under 3 years old. Sample size were 70 mothers which obtained with the cluster random sampling technique. Data collection were used questionnaire and calculated with 2005 Nutria survey and 14 levels.Results: There were no significant relationship between education level and working status on dietary intake of children under 3 years old (OR: 0,88; ᵖ-value: 0,855; CI: 0,136-4,136) and (OR: 1,29 ᵖ-value: 0,674; CI: 0.298-4.987). However, there were significant relationship between maternal knowledge and dietary intake of children under 3 years, especially related with energy and protein intake (OR: 2,14 ᵖ-value: 0,043; CI: 1,043-17,045). Conclusions: Maternal knowledge level are related to dietary intake among children under 3 years old, relared with energy and protein intake.
Association Between Lifestyle and Breast Fibroadenoma Astri, Nita; Khanifah, Milatun
Journal Midwifery Jurusan Kebidanan Politeknik Kesehatan Gorontalo Vol 11, No 1 (2025): Jurnal Midwifery
Publisher : Politeknik Kesehatan Kementrian Kesehatan Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jm.v11i1.1204

Abstract

Fibroadenoma is a benign tumor in which epithelial cells are arranged in fibrosa. Although breast fibroadenoma tumors are benign, they can still trigger the risk of developing breast cancer. The purpose of this study is to see if there is a relationship between lifestyle and the incidence of breast fibroadenoma. This Study is a quantitative research using a case-control design. The population in this study consists of all patients examined at the surgical polyclinic of kratos hospital from December 2023 to January 2024 with a population of 114. The chi square hypothesis test with a p-value of 0.000 means that < 0.05 statistically there is a significant relationship between lifestyle and the incidence of breast fibroadenoma. Lifestyle changes and hereditary factors are triggers for the onset of breast diseases, including fibroadenoma and cancer. The relationship between lifestyle and breast fibroadenoma shows that there is a statistically significant relationship between lifestyle and breast fibroadenoma. Patients with poor lifestyles were 9,679 times more likely to develop breast fibroadenoma compared to patients with good lifestyles.Keywords: Life Style, Breast Fibroadenoma
The Effort to Healthy Pregnancy Through Education on Physical Activity, Nutrition and Body Mechanics Khanifah, Milatun; Kristiyanti, Rini; Fitriyana, F; Suparni, S; Yunianti, Erma
Journal of Community Services and Engagement: Voice of Community (VOC) Vol. 3 No. 2 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/voc.v3i2.2539

Abstract

Pregnancy as a physiological process is often an obstacle to maintaining optimal health due to the discomfort that occurs during this period. Various obstacles due to discomfort can prevent pregnant women from being physically active, implementing a healthy diet. In addition, in the 3rd trimester of pregnancy, most pregnant women experience the discomfort of back pain, and many are not aware of the management that can be done. This condition causes pregnant women to be unfit during the pregnancy process. This community service program aims to increase the knowledge of pregnant women related to physical activity, nutrition and body mechanics so that the pregnancy is a quality process. This community service was conducted in Noyontaansari sub-district, the working area of Pekalongan City Noyontaan Health Center, which 29 pregnant women attended. The activity was carried out through education in pregnant women's class activities. There was an increase in the knowledge level of pregnant women before and after the education. The knowledge tested included knowledge about physical activity (exercise), nutrition, and body mechanics for pregnant women. The pre-test results showed that most (62%) had a moderate level of knowledge, 7% had less knowledge and only 31% had good knowledge. After the training, the post-test results showed that all pregnant women had a good level of knowledge. This is an indication of the success of the PkM activities in improving knowledge.