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All Journal JURNAL PENGABDIAN KEPADA MASYARAKAT Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal Farmasi Higea ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Mandala Pengabdian Masyarakat Jurnal Ilmiah Pharmacy INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Farmasi Tinctura Shihatuna : Jurnal Pengabdian Kesehatan Masyarakat JOMPA ABDI: Jurnal Pengabdian Masyarakat Jurnal Sains dan Kesehatan Journal of Health Sciences, Medicine, Biotechnology, and Pharmaceutical Research
Muhammad Subhan A Sibadu
Program Studi Farmasi, Fakultas Kedokteran, Universitas Khairun, Ternate, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Edukasi Dampak Pemanis Buatan Dalam Minuman Kemasan Bagi Pelajar di MTs Darul Ulum Sasa Kota Ternate Sibadu, Muhammad Subhan A.; Danial Fajri, Muh; Mutmainnah, Mutmainnah
Jompa Abdi: Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2026): Jompa Abdi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jompaabdi.v5i1.2189

Abstract

Kegiatan pengabdian kepada masyarakat dilakukan untuk memberi pengetahuan kepada siswa  di Mts Darul Ulum Sasa Kota Ternate mengenai efek merugikan yang bisa ditimbulkan dikemudian hari sebagai akibat berlebihan dalam mengkonsumsi minuman mengandung pemanis buatan yang beredar dipasaran saat ini. Kegiatan pengabdian ini terdiri dari dua kegiatan yakni penyuluhan dan pendampingan. Kegiatan pengabdian ini mencakup penyuluhan minuman kemasan, macam-macam pemanis buatan, efek yang ditimbulkan oleh pemanis buatan jika dikonsumsi berlebihan, kandungan dan jenis gula yang aman dikonsumsi, durasi dan jumlah minuman kemasan yang boleh dikonsumsi. Pendampingan diharapkan dapat memberikan pengetahuan baru bagi pelajar dalam melakukan skrining kandungan/komposisi pemanis buatan pada minuman kemasan yang beredar terkait nilai gizi dan batas asupan gula harian. Luaran yang dihasilkan berupa  brosur dan leaflet informatif dan hasil kegiatan dipublikasikan pada jurnal pengabdian kepada masyarakat. Dengan demikian, diharapkan para pelajar di kota Ternate umumnya dan di MTs Darul Ulum Sasa Kota Ternate khususnya bisa memilih konsumsi jajanan sehat dan terhindar dari penggunaan zat aditif pada makanan serta dapat meningkatkan kesehatan pelajar dan masyarakat pada umumnya.
Herb–Drug Interactions Between Common Indonesian Medicinal Plants and Cardiovascular Medications: A Narrative Review Aditya Sindu Sakti; Gumilar Adhi Nugroho; Febrika Wediasari; Muhammad Adil Khan; Muhammad Subhan A. Sibadu
Journal of Health Sciences, Medicine, Biotechnology, and Pharmaceutical Research Vol. 1 No. 2 (2025): Journal of Health Sciences, Medicine, Biotechnology, and Pharmaceutical Researc
Publisher : Yayasan Cendekia Gagayunan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63142/jhsmbp.v1i2.263

Abstract

The simultaneous use of herbal medicines and cardiovascular drugs is prevalent in Indonesia, a country rich in ethnomedicinal diversity. However, such combinations may lead to clinically significant herb–drug interactions, potentially compromising therapeutic efficacy and safety. This narrative review aims to summarize and evaluate the pharmacokinetic and pharmacodynamic interactions between commonly used Indonesian medicinal herbs and cardiovascular agents. A comprehensive literature search was conducted using PubMed, Scopus, ScienceDirect, and Google Scholar. The included studies reported interactions involving cytochrome P450 modulation, P-glycoprotein activity, and receptor-level mechanisms. Medicinal plants such as Panax ginseng, Allium sativum, Ginkgo biloba, Glycyrrhiza glabra, Zingiber officinale, and Cassia species were found to affect drug absorption, metabolism, and bioavailability. These interactions, primarily through CYP3A4 and P-gp modulation, altered the pharmacokinetic profiles of drugs such as warfarin, digoxin, verapamil, and simvastatin. Some herbs also exert synergistic or antagonistic pharmacodynamic effects, particularly against anticoagulants and antihypertensives. Given the chronic nature of cardiovascular therapy, herb–drug interactions pose serious clinical concerns. Enhanced awareness and monitoring are essential to prevent adverse events and therapeutic failure. Further research is needed to establish safe and evidence-based integration of herbal medicines into cardiovascular care.
Enhancing Students’ Knowledge of Clean and Healthy Living Practices at MTs Darul Ulum Sasa, Ternate City Mutmainnah Mutmainnah; Muhammad Subhan A. Sibadu; Rufaidah Azzahrah; Nurul Izzah H. L. Pasi
Shihatuna : Jurnal Pengabdian Kesehatan Masyarakat Vol 6 No 1 (2026): April
Publisher : FKM UIN Sumatera Utara Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/shihatuna.v6i1.28051

Abstract

Clean and Healthy Living Behavior (PHBS) is a promotive and preventive effort that plays a crucial role in preventing environment-based diseases, particularly among school-aged children in coastal areas. MTs Darul Ulum Sasa, located in the coastal area of Ternate City, is a school where the implementation of PHBS remains relatively low. This community service activity aimed to improve students' knowledge regarding PHBS through health education. A participatory approach was employed, consisting of pre-test, interactive educational sessions, discussions, and post-test. The activity was conducted on April 11, 2025, involving 18 students of MTs Darul Ulum Sasa. A multiple-choice questionnaire was used as the evaluation instrument to measure students' knowledge before and after the educational intervention. Data were analyzed using the Wilcoxon test. The results showed a significant increase in the mean knowledge score from 59.09 ± 29.10 in the pre-test to 79.55 ± 15.27 in the post-test, with a statistically significant difference (p < 0.05). These findings indicate that PHBS education was effective in enhancing students' understanding of the importance of personal and environmental hygiene.
Co-Authors Abulkhair Abdullah Aditya Sindu Sakti Anshari Masri Burhan, Hesti Trisnianti Danial Fajri, Muh Ermalyanti Fiskia Febrika Wediasari Fira Musriyati Karim Gumilar Adhi Nugroho Hairani Ismail Rahman M. Natsir Djide Meswara, Arfani Nuruladha Muh Danial Fajri, Muh Danial Muh. Nasrum Massi Muhammad Adil Khan Muhammad Fakhrur Rajih Hi. Yusuf Muhammad Taufiq Duppa Mutmainnah Mutmainnah Mutmainnah, Mutmainnah Nurfadilah Nurul Izzah H. L. Pasi Nurul Muhlisa Mus Rufaidah Azzahrah Sandrawati, Sandrawati Siti Marita Umaternate Somadayo, Nur Asma S Sqaputra, Jeri Cahyadi Syamsuri Syakri Zulkifli Halid