Article Per Year (5 Year)
p-Index From 2021 - 2026
2.304
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran The Indonesian Biomedical Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Pengabdian Magister Pendidikan IPA Heart Science Journal Anakes: Jurnal Ilmiah Analis Kesehatan Cardiovascular and Cardiometabolic Journal (CCJ) TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Jurnal Ilmiah STIKES Yarsi Mataram
Romi Ermawan, Romi
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Veterinary Other

Published : 13 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 13 Documents
Search

 1   2 
Predictors of right subclavian artery tortuosity in trans-radial coronary angiography access Ermawan, Romi; Pintaningrum, Yusra; Rahmat, Basuki; Putra, AASM Meiswaryasti; Indrayana, Yanna
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.13

Abstract

BACKGROUND: Trans-radial access has become the new standard and is increasingly in demand in coronary angiography. However, this method can fail due to tortuosity of the right subclavian artery. OBJECTIVES: This study aims to identify the predictors of right subclavian artery tortuosity. METHODS: This retrospective case-control study was conducted at two of the largest hospitals in West Nusa Tenggara, Indonesia. All research data were obtained from secondary sources, including video recordings of coronary angiographies, angiography reports, and patient medical records. Predictors included age, gender, smoking, height, body mass index, hypertension, diabetes mellitus, systolic and diastolic blood pressure, and random blood sugar. RESULTS: The study involved 80 subjects, divided into right subclavian artery tortuosity and normal group, with 40 subjects each. The prevalence of tortuosity was 8.1%, while the success rate of trans-radial access was 70.0%. Four significant predictors were identified: smoking (adjusted OR 0.26; p = 0.019), hypertension (adjusted OR 4.83; p = 0.020), diastolic blood pressure (adjusted OR 1.05; p = 0.044), and body mass index (adjusted OR 1.16; p = 0.035). The optimal cutoff points were determined to be a body mass index of ≥ 24.4 (sensitivity 60.0%; specificity 60.0%; p = 0.006; AUC = 0.665) and diastolic blood pressure of ≥ 78.5 mmHg (sensitivity 67.5%; specificity 67.5%; p = 0.002; AUC = 0.685). CONCLUSION: This study has identified smoking, hypertension, diastolic blood pressure, and body mass index as significant predictors of right subclavian artery tortuosity in trans-radial coronary angiography access. 
Quercetin Stabilizes Atherosclerotic Plaques by Reducing Matrix Metalloproteinase-9 Expression and Enhancing M2 Macrophage Activity in Wistar Rats Ermawan, Romi; Pikir, Budi Susetyo; Mulyanto, Mulyanto; Utomo, Budi; Widjiati, Widjiati; Oktaviono, Yudi Her
The Indonesian Biomedical Journal Vol 17, No 5 (2025)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v17i5.3790

Abstract

BACKGROUND: Quercetin has been shown to alleviate and prevent atherosclerosis. However, its role in stabilizing atherosclerotic plaques to prevent plaque rupture remains unclear. Therefore, this study was conducted to investigate the effects of quercetin on stabilizing atherosclerotic plaques.METHODS: Thirty-two Wistar rats were objected to a high-fat diet, along with an endothelial injury procedure conducted during the second week to create atherosclerotic plaque models. After six weeks, the subjects were randomly assigned to five groups consist of two control groups and three treatment groups treated with different quercetin dosages. Following the treatment, all subjects were euthanized to collect the left common carotid artery. The stability of the atherosclerotic plaques was evaluated by measuring the expression of matrix metalloproteinase-9 (MMP-9) using real-time polymerase chain reaction, assessing the activity of M1 and M2 macrophages along with the M1/M2 ratio using an enzyme-linked immunosorbent assay, and determining the maximum intima thickness through histopathological examination.RESULTS: Quercetin significantly reduced the expression of MMP-9, increased the activity of M2 macrophages, and lowered the M1/M2 ratio at doses of 10 and 50 mg/kg. However, there was no effect on M1 macrophage activity or maximum intima thickness. Path analysis indicated that quercetin primarily enhanced atherosclerotic plaque stability by reducing MMP-9 expression (p<0.001) and subsequently enhancing M2 macrophage activity (p=0.002).CONCLUSION: Quercetin administration significantly decreased the expression of MMP-9, enhanced the activity of M2 macrophages, and lowered the M1/M2 ratio at specific doses. These findings emphasize the significance of quercetin in stabilizing atherosclerotic plaques.KEYWORDS: atherosclerotic plaque, quercetin, stability, Wistar rats
Trends in Distribution and Case Fatality Rates of Cardiovascular Disease in West Nusa Tenggara General Hospital for 2014-2022 Pintaningrum, Yusra; Ermawan, Romi; Indrayana, Yanna; Putra, AASG Mas Meiswaryasti; Luthfi, M. Syahrial; Pramana, Ketut Angga Aditya Putra; Cahyani, Ni Gusti Ayu Made Sintya Dwi
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.9949

Abstract

Background: Cardiovascular disease (CVD) is the leading cause of death, which affects 17.9 million people every year. This study aimed to determine trends in CVD distribution and case fatality rate (CFR) at the West Nusa Tenggara Province General Hospital, the major referral hospital in West Nusa Tenggara Province of Indonesia Methods: This study was descriptive with a retrospective approach using medical records of patients with CVD at the West Nusa Tenggara General Hospital from January 2014 to December 2022. Consecutive sampling was performed. Data based on diagnosis, patient age, gender, and case fatality rates were analyzed descriptively and expressed in frequency and percentage distribution. Results: Of the 11,742 patients included, more than half of the patients (58.92%) were male. In this study, the most common CVD was ischemic heart disease (IHD) (44.23%, n=5,194), followed by patients with hypertension (24.55%, n=2,883), and heart failure (19.30%, n=2,265) which were dominated by males, 68.34%, 57.25%, and 50.53%, respectively. Females were lower in those CVD due to estrogen hormone which has role as cardio protector that maintains the elasticity of blood vessels and prevents atherosclerosis. Meanwhile, mitral valve disease is the fourth most common CVD, approximately 6.69%, followed by atrial fibrillation or atrial flutter at 5.97%, which were dominated by females, 57.78% and 54.17%, respectively. Our data showed that the highest CFR was in patients with atrial fibrillation or atrial flutter, which was 17.5% in 2022. Conclusion. IHD is the most commonly found in the majority of patients with CVD. The highest case fatality rate is in atrial fibrillation or atrial flutter. CVD prevalence, or CFR, is essential to focus on treatment and prevention strategies.
Co-Authors A.A.S.M. Meiswaryasti Putra Andi Annisa Amaliah Darman Aprilia, Kartika Baiq Nopria Dwi Cahyani Balqis, Fathinnisa Adillah Basuki Rahmat Basuki Rahmat Masdi Siduppa Budi Susetyo Pikir Budi Utomo Cahyani, Ni Gusti Ayu Made Sintya Dwi Devi Rahmadhona Dewi, Komang Puspa Dian Puspita Sari Indrayana, Yanna Luthfi, M. Syahrial Mulyanto Mulyanto Nimas Resti Nugraha, Gede Rama Hardy Pintaningrum, Yusra Pramana, Ketut Angga Aditya Putra Putra, AASG Mas Meiswaryasti Putra, AASM Meiswaryasti Putu Diva Gayatri Jaya Putri Ragad, Putra Ramadhani, Dhea Asty Rizky, Muhammad Ilham Siti Jaisy Millah Hadaina Widjiati Widjiati, Widjiati yanna indrayana Yudi Her Oktaviono, Yudi Her Yusra Pintaningrum Yusra Yusra Pintaningrum Yusuf Alfin Firmawan Zikriyya Melati Rahmany