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All Journal Jurnal MIPA PHARMACON CHEMISTRY PROGRESS Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ The Studies of Social Sciences Jurnal Kesehatan Tambusai Jurnal Farmasi Malacca Pharmaceutics Grimsa Journal of Science Engineering and Technology Borneo Journal of Pharmacy Jurnal Lentera: Penelitian dan Pengabdian Masyarakat
Elly Suoth
Pharmacy Study Program, Faculty Of Mathematics And Natural Sciences, Sam Ratulangi University, Manado, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Grimsa Journal of Science Engineering and Technology

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Evaluation of Antibacterial Properties from Endophytic Fungi of Chrysanthemum indicum (L.) Flowers against Escherichia coli and Staphylococcus aureus Titah Amelia Ratte; Fatimawali Fatimawali; Trina Ekawati Tallei; Elly Juliana Suoth; Irma Antasionasti; Paulina Yamlean
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 2 (2023): December 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i2.15

Abstract

Uncovering the therapeutic potential of secondary metabolites produced by plants, animals, and microbes constitutes the foundation for the development of novel medications. The objective of this investigation is to discern the classes of secondary metabolites and assess the antibacterial properties of endophytic fungal extracts obtained from Chrysanthemum indicum L. flowers. Through the isolation process, five isolates designated as JEC1, JEC2, JEC3, JEC4, and JEC5 were identified. The cultivation of endophytic fungal isolates spanned a three-week period before undergoing extraction with ethyl acetate. The phytochemical tests revealed the presence of alkaloids, flavonoids, steroids, terpenoids, saponins, and tannins in the ethyl acetate extract. Antibacterial activity was determined using the agar well diffusion method, with ciprofloxacin serving as a positive control. Notably, all ethyl acetate extracts from endophytic fungi exhibited antibacterial activity. The most substantial inhibitory diameter against Staphylococcus aureus was recorded as 19.1±0.8 mm for the JEC3 endophytic fungi, while Escherichia coli exhibited an inhibitory diameter of 16±1.1 mm for the JEC2 endophytic fungi.
Evaluation of Antibacterial Properties from Endophytic Fungi of Chrysanthemum indicum (L.) Flowers against Escherichia coli and Staphylococcus aureus Ratte, Titah Amelia; Fatimawali, Fatimawali; Tallei, Trina Ekawati; Suoth, Elly Juliana; Antasionasti, Irma; Yamlean, Paulina
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 2 (2023): December 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i2.15

Abstract

Uncovering the therapeutic potential of secondary metabolites produced by plants, animals, and microbes constitutes the foundation for the development of novel medications. The objective of this investigation is to discern the classes of secondary metabolites and assess the antibacterial properties of endophytic fungal extracts obtained from Chrysanthemum indicum L. flowers. Through the isolation process, five isolates designated as JEC1, JEC2, JEC3, JEC4, and JEC5 were identified. The cultivation of endophytic fungal isolates spanned a three-week period before undergoing extraction with ethyl acetate. The phytochemical tests revealed the presence of alkaloids, flavonoids, steroids, terpenoids, saponins, and tannins in the ethyl acetate extract. Antibacterial activity was determined using the agar well diffusion method, with ciprofloxacin serving as a positive control. Notably, all ethyl acetate extracts from endophytic fungi exhibited antibacterial activity. The most substantial inhibitory diameter against Staphylococcus aureus was recorded as 19.1±0.8 mm for the JEC3 endophytic fungi, while Escherichia coli exhibited an inhibitory diameter of 16±1.1 mm for the JEC2 endophytic fungi.
Co-Authors AA Sudharmawan, AA Abdullah, Fatamorgana Abdullah, Rezky Putri Indarwati Abdullah, Surya Sumantri Adikila, Gregorius Giani Adithya Yudistira Angellia Grace Yetto Antasionasti, Irma Aryani Tampi Astrid Maulani Runtukahu Axl Laurens Lukas Windah Billy Johnson Kepe Datu, Olvie Syenni Datu, Ronald Joy DEBY AFRIANI MPILA Defny Silvia Wewengkang Dolongtelide, Jeclin Inebel Edwin de Queljoe ERLADYS MELINDAH RUMONDOR, ERLADYS MELINDAH Fatimawali Fatimawali . Fatimawali Fatimwali Fenezia Yosevina Lumempow Fitriawati Tongkali Frenly Wehantouw Frenly Wehantouw Gabriel Tikulembang Gosal, Angel T. Gultom, Minar N. S. Hariyanto, Yuanita Amalia Henki Rotinsulu, Henki Herni E.I Simbala Herny E.I. Simbala Hindang Kaempe Hosea J. Edy, Hosea J. Hosea Jaya Edy Hotmian, Ellen Irma Antasionasti Irma Antasionasti Irma Antasionasti Irma Febrianti Wahongan Josua, Endro Julianri Sari Lebang Julianri Sari Lebang, Julianri Sari Kalalo, Marko Jeremia Kamu, Priska Eliasa Karlah L. R. Mansauda Kindangen, Eunike Elizabeth Lomboan, Evander Roliand Manik, Grace Dien Manopo, Chintia M. Margaretha, Putri Maria Immaculata Tangkau Marko Jeremia Kalalo Meilani Jayanti Nikita Thalia Ayu Jati Nursafitri Syahrudin Olvi Datu Pamudji, Gunawan Paulina yamlean Paulina Yamlean Pehino, Albrita Pendong, Christa Hana Angle Purwoko, Agus Ratte, Titah Amelia Risma Situngkir Rumondor, Erladis Rumondor, Erladys M. Rundengan, Gerald Saerang, Missyeling Siboantua Broolin Simanjuntak Sitti Juliah Nurhamidin Sri Sudewi Sri Sudewi, Sri Tania, Adinda Dwi Tifani, Tifani Titah Amelia Ratte TRINA EKAWATI TALLEI Trina Ekawati Tallei Trina Tallei Trina Tallei Tumundo, Berlian Tasya Vibrila Berliana Djanas Widdhi Bodhi Widya Astuty Lolo