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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Majalah Kedokteran Bandung Althea Medical Journal Indonesian Journal of Urology Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Jurnal Kesehatan Andalas Medical Laboratory Technology Journal Journal of Medicine and Health Majalah Patologi Indonesia Jurnal Integrasi Kesehatan dan Sains JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Ilmu Faal Olahraga Indonesia JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Indonesian Journal of Cancer Ophthalmologica Indonesiana Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD) Journal of Medicine and Health
Hasrayati Agustina
Departemen Patologi Anatomik Fakultas Kedokteran Universitas Padjadjaran
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Clinicopathological Characteristic of Radioactive Iodine-Refractory Differentiated Thyroid Carcinoma at Dr. Hasan Sadikin Hospital 2016-2021 Ayni, Tutik Nur; Agustina, Hasrayati; Hernowo, Bethy Suryawathy; Koesoemah, Raden Erwin Affandi Soeriadi; Azhar, Yohana
Majalah Patologi Indonesia Vol. 33 No. 1 (2024): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v33i1.606

Abstract

Background Initial therapy for differentiated thyroid carcinoma (DTC) is thyroidectomy with or without cervical lymph node dissection. Furthermore, radioactive iodine (RAI) is given to patients by considering risk stratification and other patient factors. Although most cases of DTC have a good prognosis after standard therapeutic approaches, the risks of local recurrence and distant metastases can be as high as 20% and 10%. Among these patients, two-thirds showed RAI-refractory. This is concerning because 10-year survival rate is less than 10%. This study aimed to analyze the clinicopathological characteristics of RAI-refractory DTC.   Methods This is a case-control study. Data was collected from the Department of Nuclear Medicine and Molecular Theranostics and Department of Anatomical Pathology, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin Hospital, Bandung period 1 January 2016-31 December 2021.   Results Clinicopathological factors associated with RAI-refractory DTC are age, sex, aggressive histologic subtype, LVI (lymphovascular invasion), m-ETE (microscopic extrathyroid extension), TNM (tumor, nodal, metastasis) stage, and ENE (extranodal extension), with p-value <0.05. Meanwhile, there was no significant difference in the histologic type between RAI-refractory and non-RAI-refractory groups.   Conclusion In the pathology report, it is necessary to include prognostically relevant tumor histopathological characteristics. In addition to histologic type, histologic subtype, and tumor size, other features such as presence and extent of capsular invasion, LVI, microscopic and macroscopic ETE, ENE, and number and size of metastatic lymph nodes, have been shown to provide additional prognostic information and are required in standard pathology reports for DTC.
Hubungan Karakteristik dengan Tingkat Pengetahuan Perempuan Usia Reproduktif mengenai Berat Badan Lahir Rendah dan Spektrum Plasenta Akreta pada Salah Satu Komunitas Perguruan Tinggi Swasta di Bandung Agustina, Hasrayati; Dewayani, Birgitta Maria; Suryanti, Sri; Hernowo, Bethy Suryawaty; Kharisma, Yuktiana
Jurnal Integrasi Kesehatan dan Sains Vol 6, No 1 (2024): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v6i1.11816

Abstract

Berat badan lahir rendah (BBLR) dan spektrum plasenta akreta (SPA) merupakan salah satu masalah kesehatan yang menyebabkan morbiditas serta mortalitas ibu dan janin yang signifikan. Pengetahuan tentang kesehatan sangat penting untuk mengurangi efek buruk tersebut. Penelitian bertujuan mengetahui tingkat pengetahuan perempuan usia reproduktif mengenai BBLR dan SPA. Studi potong lintang berbasis masyarakat tersebut dilakukan pada bulan Agustus 2021 pada 65 partisipan komunitas usia reproduktif pada salah satu perguruan tinggi swasta di Bandung melalui pengisian kuesioner yang telah tervalidasi. Analisis data menggunakan uji chi-square melalui perangkat lunak STATA versi 15 untuk mengevaluasi hubungan antara karakteristik partisipan dengan tingkat pengetahuan BBLR dan SPA. Hasil penelitian sebanyak 54% partisipan memiliki pengetahuan BBLR dan SPA itu cukup.  Terdapat hubungan signifikan karakteristik pekerjaan (p=0,02) dengan tingkat pengetahuan BBLR dan SPA, sedangkan karakteristik usia (0,009), status pernikahan (0,24), dan pendidikan (0,2) tidak berhubungan dengan tingkat pengetahuan mengenai BBLR dan SPA. Terdapat beberapa faktor yang memengaruhi pengetahuan, seperti usia, pendidikan, sosial budaya, ekonomi, lingkungan, serta pekerjaan. Simpulan, pemberian stimulus berupa informasi seputar BBLR dan SPA melalui kegiatan sosialisasi yang berkesinambungan diharapkan dapat menjadi salah satu solusi untuk meningkatkan pengetahuan pada komunitas perempuan usia reproduktif AbstractLow birth weight (LBW) and placenta accreta spectrum (PAS) are health problems that cause significant maternal and fetal morbidity and mortality. Health knowledge is very important to reduce these adverse effects. This study aims to determine the level of knowledge of women of reproductive age about LBW and PAS. The cross-sectional community-based study was conducted in August 2021 on 65 participants of the reproductive age community at a private university in Bandung by filling out a validated questionnaire. Data analysis used the Chi-Square test by STATA software version 15 to evaluate the association between participant characteristics and knowledge level of LBW and PAS. The results showed that most of the participants had sufficient knowledge of LBW and PAS (54%). There was a significant relationship between job characteristics (p=0.02) and the level of knowledge of LBW and SPA, while the characteristics of age (0.009), marital status (0.24), and education (0.2) are not related to the level of knowledge of LBW and SPA. Several factors influence knowledge, such as age, education, socio-culture, economy, environment, and work. In conclusion, health education in the form of information about LBW and PAS through continuous counseling is expected to be one of the solutions to increase knowledge in the community.
Clinicopathological Characteristics of Ocular Surface Squamous Neoplasia in National Eye Center, Cicendo Eye Hospital Bandung from 2019 to 2022 Nia Nuraeni; Aminah, Hermin; Agustina, Hasrayati; Mardianty, Friska
Majalah Patologi Indonesia Vol. 34 No. 2 (2025): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v34i3.649

Abstract

Introduction Ocular surface squamous neoplasm (OSSN) comprises a broad spectrum of dysplastic alterations of the squamous epithelium of the conjunctiva, ranging from conjunctival squamous intraepithelial neoplasm (CSIN) to squamous cell carcinoma (SCC). The aim of this study was to describe the clinicopathological characteristics of OSSN at National Eye Center, Cicendo Eye Hospital Bandung from January 2019 to December 2022. Methods We collected OSSN data from 2019 to 2022. The collected data were the patient's age, gender, education, occupation, laterality, clinical features, recurrence, and classification of tumor according to the 2022 WHO classification. Results: A total of 128 cases were collected. The most common tumor identified was SCC (48.4%), followed by CSIN with severe dysplasia (25%), moderate dysplasia, and mild dysplasia (14.8% and 11.7%, respectively). The average patient’s age was 53.1 years (M = 53.1, SD =16.9), predominantly males (68%), education completed elementary school (52.3%), and more patients worked outdoor (59.4%). The most common affected site was the left eye (53.9%), and the tumor located in the nasal region (78.1%) with clinical features is papilliform (64.1%). Conclusion OSSN was predominant in elderly male patients. The majority of cases were seen in the left eye, primarily in the nasal area. The majority of patients had completed elementary school and worked outdoors. Additionally, the clinical symptoms showed that most patients had papilliform. In patients with OSSN, SCC was the most common anatomical pathology discovered. Moreover, recurrence was higher in SCC cases.
Co-Authors Abdul H. Hassan Abdul H. Hassan, Abdul H. Abdul Hadi Hassan, Abdul Hadi Afiati Afiati Aminah, Hermin Andika Prahasta Ayni, Tutik Nur Azhar, Yohana Bethy S Hernowo Bethy S Hernowo, Bethy S Bethy S. Hernowo Bethy S. Hernowo Bethy Suryawathy Hernowo Bethy Suryawati Hernowo Bethy Suryawati Hernowo Birgitta Maria Dewayani Dewayani, Birgitta Maria Dewi, Yussy A Dimyati Achmad Djajakusumah, Teguh M Dwi Putri, Riska Edward Jaya Hadi Elsa Gustianty Giovani, Octavianus Hadaral Hudanul Qolbi Hermin Aminah Usman Hernowo, Bethy Suryawaty Herry Yulianti Hidayat, Peri Hikmat Permana Inas Susanti Kiki Akhmad Rizki, Kiki Akhmad Koesoemah, Raden Erwin Affandi Soeriadi Kusumawati, Maya Lili Sumarni Maman Abdurahman Mardianty, Friska Maretha Amrayni Maula Rifada Mifatuhrachman Mifatuhrachman Mifatuhrachman, Mifatuhrachman Muhammad Iman Pratama Putra Nanny Natalia Mulyani Soetedjo Naomi, Sonya M Nia Nuraeni Niswan Helja Batubara Nita Novita Nova Sylviana Octavianus Giovani Odilia Dos Reis, Odilia Dos Ris Kristiana Ris Kristiana, Ris Ritonga, Ervita Siska Dwiyantie Wahyuni Sitanggang, Rupita Sari Endangena Sri Maryanti Sri Mulyati Sri Mulyati Sri Suryanti Susi Heryati Teguh M Djajakusumah Teguh Marfen Djajakusumah, Teguh Marfen Yasni Iryani Widiasih Yenni Wisudarma Yenni Wisudarma Yenni Wisudarma, Yenni Yohana Azhar Yohana Azhar Yuktiana Kharisma Zahra Nurusshofa