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Serum Procalcitonin (PCT) Level In Acute Kidney Injury (AKI) In Critical Patients: Acute Kidney Injury (AKI) In Critical Patients Iwan Tona, Azwar; Syukri, Maimun
Journal of Society Medicine Vol. 1 No. 2 (2022): November
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (427.923 KB) | DOI: 10.47353/jsocmed.v1i2.8

Abstract

Early prediction and avoidance of aggravation of AKI will be useful in identifying patients at risk of developing a higher degree of AKI. Many studies have been conducted to prevent AKI and find biomarkers to predict AKI. Many studies have identified biomarkers of AKI, such as neutrophil-associated lipocalin (NGAL), cystatin C, interleukin-18, and tissue inhibitors of metalloproteinase-2 (TIMP-2). Yet few have investigated the role of PCT as a predictor of AKI. The pathophysiological mechanisms that explain the association between serum PCT and AKI remain unclear. Various inflammatory responses are thought to play a role in the AKI development. PCT acts as a chemoattractant in the ​​inflammation area and causes more monocytes to invade the ​​inflammation. PCT is initially produced in adherent monocytes and then contributes to an increase in circulating PCT by attracting parenchymal cells as they attach directly to activated monocytes. High PCT levels ultimately act as a direct chemoattractant to monocyte counts.
Burnout and study engagement among medical students during COVID-19 pandemic: A cross-sectional study in Aceh, Indonesia Al-Gunaid, Seba; Syukri, Maimun; Kurniawan , Ferry D.; Rizal, Syamsul; Novirianthy, Rima
Narra X Vol. 3 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v3i1.165

Abstract

Medical students are particularly vulnerable to burnout due to the demanding and resource-constrained nature of their training. Burnout negatively impacts academic and personal well-being, potentially impacting future professional practice and patient care. To date, no studies have examined burnout prevalence among medical students in Aceh. The aim of this study was to determine the association between burnout and academic engagement among medical students at Syiah Kuala University, as well as the relationship with age, sex, and year of study. This cross-sectional study was conducted among medical students in Aceh, Indonesia, between October 1, 2021, and March 13, 2022. Total sampling was employed to select study participants. Data were collected using an e-questionnaire using the Oldenburg Burnout Inventory questionnaire adapted for students (OLBI-S) and Utrecht Work Engagement Scale for Students (UWES-S-9) for academic engagement. The total number of participants was 286 students. Most participants were female (n=202, 70.6%), while male students were 84 (29.3%). The prevalence of burnout was 36% (n=102). Gender (p=0.65) and study year (p=0.62) were not associated with disengagement, a subscale of the OLBI-S. Similarly, exhaustion scores did not differ significantly by gender (p=0.48) or study year (p=0.28). In conclusion, fewer than half of the medical students experienced burnout during the COVID-19 pandemic, with no association found between burnout and gender or study year.
Perbandingan Rasio Albumin Kreatinin Urin Sebelum Dan Setelah Puasa Pada Penyakit Ginjal Diabetik: Comparison of Urinary Creatinine Albumin Ratio Before and After Fasting in Diabetic Kidney Disease Hasan, Desi Salwani; Syukri, Maimun; Balqis, Ummu; Suhanda, Rachmad
Journal of Medical Science Vol 6 No 2 (2025): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v6i2.246

Abstract

Pembatasan asupan kalori selama berpuasa dapat menurunkan berat badan, namun juga memiliki risiko perburukan fungsi ginjal pada pasien dengan penyakit ginjal diabetik. Rasio albumin kreatinin merupakan salah satu penanda perburukan fungsi ginjal.  Penelitian ini bertujuan untuk mengetahui perbandingan rasio albumin kreatinin urin sebelum dan setelah berpuasa pada pasien penyakit ginjal diabetik. Penelitian ini merupakan penelitian cohort prospektif yang dilakukan mulai 1 Maret 2024-31 Mei 2024 di Poliklinik Endokrin dan poliklinik ginjal Hipertensi Rumah sakit dr Zainoel Abidin, melibatkan subyek penyakit ginjal diabetik yang menjalani puasa Ramadhan minimal 7 hari berturut, usia > 18 tahun, proteinuria +1 atau lebih berdasarkan urinalisis dan kriteria ekslusi adalah sindroma nefrotik atau penyaki glomerulus dan lupus eritematosus sistemik. Perbandingan kadar albumin kreatinin rasio sebelum dan setelah puasa Ramadhan menggunakan uji T-test berpasangan bila distribusi data normal dan uji Wilcoxon bila distribusi data tidak normal dengan tingkat signifikansi pengambilan keputusan pada p<0.05. Penelitian melibat 37 subyek dengan penyakit ginjal diabetik, laki laki lebih banyak dari Perempuan (54,1 %) dengan rerata usia 51,41±9,39 tahun. Median Rasio Albumin kreatinin sebelum puasa Ramadhan adalah 1359(10,57-12442) mg dan 1015(7,89-9764) mg setelah 7 hari menjalani puasa. Perbandingan rasio albumin kreatinin urin pada pasien penyakit ginjal diabetik sebelum dan sesudah puasa Ramadhan tidak menunjukkan perbedaan yang bermakna secara statistik dengan nilai P 0,140. Simpulan: terdapat penurunan rasio albumin kreatinin namun tidak berbeda secara statistik.