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All Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal teknologi Kesehatan Borneo Eureka Herba Indonesia Journal of Economics and Public Health Journal of World Future Medicine, Health and Nursing Journal of Pharmacopoeia Dirya : Journal of Economic Management
Khrisna Agung Cendekiawan, Khrisna Agung
Fakultas Farmasi Universitas Jember
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Potential Secondary Metabolites in Guava (Psidium guajava) Assisted by Radar Chart Analysis (RCA) and Area Under Curve (AUC) Cendekiawan, Khrisna Agung; Kintoko, Kintoko; Yuliani, Sapto; Anggraeni, Linda Suci
MAGNA MEDIKA Berkala Ilmiah Kedokteran dan Kesehatan Vol 12, No 2 (2025): AUGUST
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.12.2.2025.196-207

Abstract

Background:  Diarrhea is a common health problem worldwide, with causes ranging from microbial infections to gastrointestinal disorders. Conventional diarrhea treatments usually involve synthetic drugs, but medicinal plant-based therapies, such as those containing secondary metabolite compounds in guava leaves, show promising potential. In this systematic review, we aimed to identify potential metabolite compounds.Objective: In this systematic review, we aim to identify potential secondary metabolite compounds in medicinal plants with antidiarrheal effects and explore the biological mechanisms of action involved.Methods: Using a literature review, relevant articles were analyzed from reputable scientific databases.Results: The results of the review indicate that compounds such as flavonoids, polyphenols, tannins, and saponins in guava leaves possess antidiarrheal potential, contributing to the regulation of intestinal motility, inhibition of inflammation, and alteration of the gut microbiota composition.Conclusion: The results of this study indicate that medicinal plants and their secondary metabolites can be a promising alternative for safer and more efficient antidiarrheal therapy.
Co-Authors Agus Mukholid Alfiansyah, Andika Anggraeni, Linda Suci Anggraeni, Lutvi Anggraeni, Lutvi Anggraeni Arnes Yuli Vandika Fadli Fadli Faradina, Anggia Hariati , Fitria Heru Sulistijono Kintoko Kintoko Lia Fitriyaningrum Minarti Minarti Muntasir, Muntasir nafisah isnawati Pangesti, Yuli Putra, Dewa Ngakan Gde Wahyu Mahatma Rasmita, Dina Runtu, Andro Ruben Sapto Yuliani Setyorini, Dhiana Shinta Mayasari Sugiah, Sugiah Wardhani, Firdha Aprillia Wulandari, Hilwiyah Septi Wuryandari, Tutik Zani, Benny Novico