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Journal : International Journal on Food, Agriculture and Natural Resources (IJFANRES)

Optimization of The Combination of CMC-Na and Glycerin in Tobacco (Nicotiana tabacum L.) Hand Sanitizer Gel Using The Simplex Lattice Design Andi Eko Wiyono; Iftitah Ariyanti Safitri; Andrew Setiawan Rusdianto; Miftahul Choiron; Ardiyan Dwi Masahid
International Journal on Food, Agriculture and Natural Resources Vol 4, No 1 (2023): IJ-FANRes
Publisher : Food, Agriculture and Natural Resources - NETWORKS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46676/ij-fanres.v4i1.108

Abstract

Tobacco leaves have active compounds such as phenols and alkaloids that can be used as antibacterial and antiseptic because they can damage the cell components of microorganisms. Tobacco leaf extract in hand sanitizer gel has been shown to have antibacterial activity against Staphylococcus aureus and Eschericia coli bacteria at a minimum concentration of 0.25%. Hand sanitizer is an antiseptic product that is used to clean hands and is preferred because it is practical, has a cooling and dries quickly when compared to hand soap. To make hand sanitizer products that are safe for the skin, various chemical compounds are used as building blocks, including CMC-Na and glycerin. CMC-Na acts as a gelling agent and glycerin has a role as a vehicle. This study aims to obtain the optimum formula for hand sanitizer gel preparations with variations in the concentration ratio of CMC-Na and glycerin using Simplex Lattice Design (SLD) and to determine the effect of variations in the concentration ratio of CMC-Na and glycerin on physical, chemical, and microbiological characteristics of the results of the optimum formula for hand sanitizer gel preparations. The research method used in this study is a type of laboratory experiment using Completely Randomized Design (CRD). The data obtained from the research results were processed using Analysis of Variance (ANOVA) with a 95% confidence level and continued with Duncan's Multiple Range Test at a significance level of 5%. The results showed that there were 3 optimum formulas for hand sanitizer gel of tobacco leaf extract based on the desirability value, 0.912 (Formula 1), 0.457 (Formula 4) and 0.653 (Formula 5). The variation of the concentration ratio of CMC-Na and glycerin in the optimum formula showed that CMC-Na had the most dominant influence on physical (homogeneity), chemical (total flavonoid) and microbiological (antibacterial and antiseptic) characteristics. Meanwhile, glycerin has the most dominant influence on product viscosity stability. The three optimum formulas have homogeneous gel characteristics.
Physical And Chemical Characteristics Of Cassava Leaf Chlorophyll As Natural Dye Powder (Manihot esculenta Cranzt) With Tween 80 And Alkaline Type Variations Winda Amilia; Andi Eko Wiyono; Retha Talia Shasabilah; Miftahul Choiron; Maria Belgis
International Journal on Food, Agriculture and Natural Resources Vol 4, No 1 (2023): IJ-FANRes
Publisher : Food, Agriculture and Natural Resources - NETWORKS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46676/ij-fanres.v4i1.137

Abstract

Cassava leaves are a good source of minerals Ca, Mg, Fe, Mn, Zn, vitamins A and B2 (riboflavin). In addition, cassava leaves contain bioactive compounds that are beneficial to the body, namely chlorophyll. Chlorophyll is a natural green dye that is generally found in plants whose composition is contained in the chloroplasts. The amount of chlorophyll in cassava leaves is classified as good, namely 18.141 mg/l. This is one of the potentials to utilize cassava leaves as natural dyes. Production of cassava leaf coloring powder using foam mat drying. Foam mat drying is a method of foaming technique by adding foam. The foaming agent used is tween 80 which can produce foam or froth and speed up drying. Chlorophyll can be easily degraded due to exposure to heat (temperature), acids, light and alcohol. The use of NaHCO3 can increase the levels of chlorophyll in the leaves. In addition, the use of MgCO3 can maintain the green color of leaf chlorophyll. The purpose of this study was to determine the interaction of tween 80 variations and types of bases on the physical and chemical profiles of cassava leaf natural dye powder. The research design used a laboratory experimental method with two variations, namely tween 80 and base type. In this study there were four treatment combinations. This study used several test parameters including physical and chemical tests, namely dissolving time, color (L, a, b), total dissolved solids, pH, water content, and chlorophyll content. The results showed that the variation of tween 80, the type of base and the interaction of the two had a significant effect on the b color value and the L color value in cassava leaf natural dye powder.