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Journal : World Nutrition Journal

The effect of dietary fiber on insulin resistance in obesity: A literature review Santri Dwizamzami Faridahanum; Fariz Nurwidya; Yohannessa Wulandari
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0009

Abstract

Introduction Obesity has become a significant public health problem in developing countries such as Indonesia. According to WHO, 13% of adults aged 18 years and over were obese in 2016. In Indonesia, 21.8% of adults were obese. In obesity, the body's resistance to insulin will develop. Some studies showed a probable link between dietary fiber and insulin resistance. This research aims to investigate the role of the dietary fiber on insulin resistance in obesity. Methods: This study is a literature study to determine the effect of dietary fiber on insulin resistance in obesity with sources from scientific publications 10 years back. The databases were PubMed and Google Scholar. The search term used was using the explode function for subgroup terms with operators (“and,” or) for “dietary fiber”, “obesity”, “insulin resistance”. Hand-searching was used to identify further potential eligible studies. There were no language restrictions, however only publications with full texts available were included. Total 138 publications titles and abstract were screened for their relevance to this literature review. Results: A total of 25 publications were finally included. There are cross-sectional studies, randomized clinical trial, cohort studies, and article review. Some studies showed that dietary fiber had an effect on improve insulin resistance, but other studies did not find this effect. Conclusion: The studies of dietary fiber effect on insulin resistance have inconsistent results. In the future, further studies are required for better understanding about the effect of dietary fiber on insulin resistance in obesity
Malnutrition and lung cavity formation in pulmonary tuberculosis patients Christi Giovani Anggasta Hanafi; Fariz Nurwidya; Wiji Lestari; Heidy Agustin
World Nutrition Journal Vol. 7 No. 01 (2023): Volume 07 Issue 1, August 2023
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/10.25220/WNJ.V07.i1.0005

Abstract

Background: Tuberculosis (TB) is an infectious disease and still major public health threat globally, also one of the leading causes of death worldwide. One of the characteristics found in pulmonary TB patient is lung cavity on their chest radiograph. This is related to many aspects, including slower conversion of sputum cultures, treatment failure and relapse, drug resistance, higher bacillary load, even higher infection transmission rates. Some studies before had found that the lung cavity is affected by many factors, such as elder age, sex, diabetes mellitus, and malnutrition. Meanwhile, malnutrition itself in pulmonary TB patients is found to be related to each other, this article review how malnutrition affects the formation of lung cavity in pulmonary TB patients. Objective: To observe the relationship between malnutrition and lung cavity formation in pulmonary tuberculosis patients. Method: In this paper, we provide a literature review. The method to achieve the objective consists of using literature exploration, which was conducted from October 2022-February 2023 by searching the relevant studies from several databases. Results: Cavity formation in pulmonary TB patients is a complex mechanism from many factors contributing, including the immune system of the host. Studies show that malnutrition in pulmonary TB patients plays important role linked to lung cavity formation since malnutrition affects both innate and cellular immune response in host. Conclusion: Malnutrition is more predominating in pulmonary TB patients and is related to incidence of lung cavity in pulmonary TB patients, therefore plays role in the severity of the disease in pulmonary TB.
Correlation between total animal and plant protein intake, with body mass index in tuberculosis patients during the intensive phase in Dili and Oecusse marques lafo, merita; Chandra, Dian Novita; Nurwidya, Fariz; Sequiera, Ercia Maria da Conceicao
World Nutrition Journal Vol. 8 No. S1 (2024): Selected conference proceedings of the Nutri Symposium 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.S1.0026

Abstract

Tuberculosis causes decreased appetite and hypermetabolism, disrupting protein breakdown and synthesis, leading to malnutrition. Proteins, as the primary source of amino acids, support immune cells and help prevent malnutrition and susceptibility to other infections. The intensive phase of tuberculosis therapy is crucial for enhancing immune defense, reducing the bacterial load, and decreasing energy expenditure, thereby increasing body weight.
Relationship between protein intake and nutritional status with response therapy of intensive phase in pulmonary tuberculosis patients in Dili and Oecusse Marques Lafo, Merita; Chandra, Dian Novita; Nurwidya, Fariz; Sequeira, Ercia Maria da Conçeição
World Nutrition Journal Vol. 8 No. i2 (2025): Volume 08 Issue 2, February 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i2.0004

Abstract

Background: Tuberculosis (TB) infection triggers a decrease in appetite and disrupts protein metabolism. Protein provides the main source of amino acids for immune system formation and tissue repair, both of which are impaired in tuberculosis patients. Intensive phase anti-tuberculosis therapy aims to boost immunity, reduce bacterial load, and improve nutritional status. Pulmonary TB is the leading cause of death in Timor Leste (94% mortality rate by 2021), yet few studies have explored the relationship between nutrition and treatment response. This study investigated the relationship between protein intake, nutritional status, and treatment response in pulmonary TB patients undergoing intensive therapy in Dili and Oecusse. Method: Using a cross-sectional study design, 104 participants were recruited using consecutive sampling. Data collection included both primary and secondary data. Analyses were conducted using the independent samples t-test, Mann-Whitney, and Fisher's Exact Test. Results: There are 66.3% at risk of malnutrition based on upper arm circumference, a mean body mass index of 17.86 kg/m². The median daily protein intake was 1.07 g/kgBW/day, with lower intake of animal protein compared to plant protein (0.44 g/kgBW/day vs. 0.59 g/kgBW/day). The study found no significant relationship between protein intake and nutritional status in response to the intensive phase therapy (p>0.05). Conclusion: There is no significant relationship between protein intake and nutritional status in response to the intensive phase therapy. Further research with a case-control study design is needed to confirm findings and evaluate factors affecting unbalanced therapy response.
Relationship between age and vas appetite score among patients with post-tuberculosis lung disease at Persahabatan National Respiratory Referral Hospital, Jakarta Mahardika, Linda; Nurwidya, Fariz; Singal, Anna Maurina
World Nutrition Journal Vol. 9 No. S1 (2025): Vol. 9 No. S1 (2025): Selected conference proceedings of the Nutri Symposium 2
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.S1.0022

Abstract

Background: Post-tuberculosis lung disease (PTLD) is a form of progressive lung tissue damage following tuberculosis (TB) infection. In addition to clinical symptoms, patients with PTLD often experience nutritional problems. Appetite plays a crucial role in determining adequate nutrient intake, which can affect nutritional status, the recovery process, and overall quality of life. One factor that may influence appetite is age. Although age is known to affect appetite, the relationship between the two has not been studied, particularly in patients with PTLD at Persahabatan Hospital, National Respiratory Centre.