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Cowpea (Vigna unguiculata) Extract Reduce Malondialdehyde Levels and Prevent Aortic Endothelial Cell Decline in Ovariectomized Rats Ni Putu Sri Haryati; Elisa Danik Kurniawati; Tanti Tri Lestary; Eviana Norahmawati; I Wayan Arsana Wiyasa; Dwi Yuni Nur Hidayati; Tatit Nurseta
Medical Laboratory Technology Journal Vol. 7 No. 2 (2021): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (484.221 KB) | DOI: 10.31964/mltj.v0i0.402

Abstract

Estrogen has anti-oxidative and anti-inflammatory properties, but its levels decrease in postmenopausal women who can trigger oxidative stress. One of the most damaging effects of ROS is lipid peroxidation, and the end product is Malondialdehyde (MDA). Similarly, aging endothelium has increased oxidative stress and endothelial cell sensitivity to apoptosis. This study aimed to determine the effect of cowpea extract on serum MDA levels, aortic endothelial cell counts, and brain MDA levels in the ovariectomy model. Cowpea extract can be used as an alternative to prevent and overcome the effects that occur during menopause, such as cardiovascular problems, decreased bone mineral density, and dementia. The study used 15-month-old female Rattus norvegicus, divided into six groups (OVX, SHAM, OVX+estradiol, OVX+Vu 1.25; 2.5; and 5 mg/kg BW/day). Serum and brain MDA levels were examined by ELISA method, while the number of aortic endothelial cells were examined on histopathological preparations with Hematoxylin & Eosin (HE) staining. The mean value of serum and brain MDA levels decreased with an increase in the dose given (p-value 0.016). The mean value of aortic endothelial cells between the dose groups did not significantly differ. However, the mean value showed an increasing trend as the dose of cowpea extract was given. The results of this study indicate that the extract of cowpea has the potential as an antioxidant to reduce serum and brain MDA levels, prevent a decrease in the number of aortic endothelial cells. As prevention, cowpea extract can be used as an antioxidant and consumed since premenopause to minimize problems that occur during postmenopause.
Study of Old Relationship of Contraceptive Use of DMPA (Depomedroxy Progesterone Acetate) to Health Problems in Menopause Tanti Tri Lestary; Ratnanengsih; Grace Pongmekkita
Formosa Journal of Social Sciences (FJSS) Vol. 2 No. 2 (2023): June, 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjss.v2i2.4539

Abstract

Depomedroxy Progesterone Acetate is a synthetic progesterone used in the injection method in the Family Planning program. This method is familiarly known as 3-month injection KB in the community. Injecting family planning services can be accessed at Independent Midwives' Practices, Doctor's Practices and Community Health Centers. Based on data for 2021, the most widely used method is injection, which is 33.1% (RI Ministry of Health, 2022). However, using it for a long time, this method will cause a hypoestrogen-like state like menopause. This causes health problems such as decreased libido and increased BMI (Body Mass Index). This research is a qualitative research that uses Chi-Square analysis to assess the relationship between the variables studied. The population in this study were 3-month injection acceptors at PMB Lia Sofa with a sampling technique using Acidental Sampling. This research was conducted from April to July 2022 using a questionnaire as a tool. From this study, it was found that there was a relationship between the duration of 3 months of injection injections with an increase in BMI and a decrease in libido
SOSIALISASI EDUKASI TENTANG ASUHAN KEBIDANAN BERBASIS BUDAYA GUNA MENINGKATKAN PENGETAHUAN PADA KELOMPOK IBU HAMIL Nurrahmi Umami; Ririn Ariyanti; Ika Yulianti; Nur Citra; Ratnanengsih Ratnanengsih; Doris Noviani; Gusriani Gusriani; Tanti Tri Lestary
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 7, No 3 (2023): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v7i3.16484

Abstract

ABSTRAKPelayanan kebidanan yang optimal merupakan faktor penting untuk mencegah terjadinya komplikasi juga mengurangi angka kesakitan dan kematian ibu dan bayi. Memahami perilaku terkait pelayanan kebidanan khususnya yang berhubungan dengan aspek budaya menjadi hal yang penting untuk mengetahui dampak kesehatan bagi ibu dan bayi. Tujuan pengabdian ini untuk meningkatkan pengetahuan dan pemahaman ibu terkait asuhan kebidanan dari perspektif budaya. Metode pelaksanaan dilakukan dengan tiga tahap yakni, tahap persiapan, tahap pelaksanaan dan tahap akhir. Kegiatan dilakukan pada tanggal 13 Juni 2023 di Kabupaten Malinau dengan jumlah peserta 30 orang yang merupakan kelompok ibu hamil. Peningkatan pengetahuan kelompok ibu hamil di evaluasi dengan kuis pada akhir kegiatan dengan hasil kelompok ibu hami dapet membedakan mana yang termasuk asuhan kebidanan secara fakta dan asuhan kebidanan mitos dilihat dari aspek kebudayaan. Kesimpulan ada peningkatan pengetahuan kelompok ibu hamil setelah dilakukan sosialisasi terkait asuhan kebidanan berbasis budaya. Kata kunci: edukasi; asuhan kebidanan; budaya; ibu hamil. ABSTRACTOptimal midwifery services are an important factor in preventing complications as well as reducing maternal and infant morbidity and mortality. Understanding behavior related to midwifery services, especially those related to cultural aspects, is important to know the health impact on mothers and babies. The purpose of this service is to increase mothers' knowledge and understanding regarding midwifery care from a cultural perspective. The implementation method is carried out in three stages: the preparatory stage, the implementation stage, and the final stage. The activity was carried out on June 13, 2023, in Malinau Regency, with 30 participants who were pregnant women. The increase in knowledge of the pregnant women group was evaluated with a quiz at the end of the activity, with the results showing that the group of pregnant women was able to distinguish between factual midwifery care and mythical midwifery care from a cultural perspective. In conclusion, there was an increase in the knowledge of the pregnant women's group after socialization regarding culture-based midwifery care. Keywords: education; midwifery care; culture; pregnant woman
ASUHAN KEBIDANAN KOMUNITAS GERIMIS PAGI (GERAKAN IBU HAMIL SEHAT, PENCEGAHAN IBU HAMIL DENGAN RESIKO TINGGI ANEMIA) Tanti Tri Lestary; Nurrahmi Umami; Idha Farahdiba; Annisa Eka Permatasari
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 4 (2024): Volume 5 No. 4 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i4.31276

Abstract

Kehamilan merupakan salah satu kondisi rentan bagi kaum perempuan terhadap kekurangan zat besi. Kekurangan zat besi mempengaruhi proses perkembangan janin dan pertumbuhan berbagai organ tubuh selama proses kehamilan. Pada saat hamil, tubuh ibu memerlukan zat besi untuk membantu pembentukan sel darah merah dan transportasi oksigen ke tubuh. Kebutuhan zat besi meningkat karena peningkatan volume darah, kekurangan zat besi dapat menyebabkan anemia pada ibu hamil. Kegiatan pegabdian masyarakat GERIMIS PAGI bertujuan untuk memberikan edukasi terhadap masyarakat khususnya ibu hamil dalam mengatasi masalah kesehatan yang berhubungan anemia menggunakan pendekatan asuhan kebidanan. Kegiatan ini dilaksanakan pada rabu 6 Desember 2023, metode yang di gunakan dalam kegiatan penyuluhan dan pelatihan kepada masyarakat yang sasarannya adalah ibu hamil yang berjumlah 20 orang yang pelaksanaannya dilakukan selama 1 hari. Hasil kegiatan pegabdian dimana ibu hamil memiliki pengetahuan tentang anemia dan cara pengolahan makanan yang tepat untuk memenuhi nutrisi selama kehamilan,serta adanya sikap positif dan mampu melakukan secara mandiri pengolahan makanan yang baik di rumah.