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All Journal e-Journal BUDIDAYA PERAIRAN Majalah Kesehatan FKUB Jurnal Akuatiklestari Indonesian Aquaculture Journal Jurnal Riset Akuakultur Jurnal Mina Sains Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Abdi Insani Jurnal Pengabdian kepada Masyarakat Nusantara Tri Dharma Mandiri: Diseminasi dan Hilirisasi Riset Kepada Masyarakat (Jurnal Pengabdian Kepada Masyarakat) LEBAH Depik Jurnal Ilmu-Ilmu Perairan, Pesisir dan Perikanan Depik Jurnal Ilmu-Ilmu Perairan, Pesisir, dan Perikanan Jurnal Ragam Pengabdian Cermin Dunia Kedokteran JARI : Jurnal Akuakultur Rawa Indonesia
Taufiq Abdullah, Taufiq
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Ketidakseimbangan Elektrolit yang Menyebabkan Fenotipe Brugada: Perpotongan Kompleks antara Hiperkalemia, Hiponatremia, dan Asidosis – Laporan Kasus: Laporan Kasus Imowanto, Yuddy; Abdullah, Taufiq; Wahyuni, Sri
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.1809

Abstract

Introduction: Brugada phenocopies (BrP), which are different from real congenital Brugada syndrome (BrS), are clinical entities with different etiology. BrP can manifest in a range of conditions, such as metabolic disturbances like hypokalemia, hyperkalemia, hypophosphatemia, hyponatremia, and acute toxicity. Case: Brugada phenocopy was observed in the ECG of a 68-year-old male, resolved following the correction of hyperkalemia, hyponatremia, and acidosis. The patient presented with septic shock and multiorgan dysfunction, which contributed to severe electrolyte imbalance and metabolic derangements. Despite initial stabilization and improvement in ECG findings after targeted correction, the patient ultimately developed progressive clinical deterioration. Discussion: Recognizing BrP helps identify reversible causes of the ECG changes, allowing for proper treatment and prevention of complications. This case highlights the importance of evaluating underlying metabolic and systemic conditions when encountering Brugada-like ECG patterns. Conclusion: Brugada phenocopy can occur in hyperkalemia and hyponatremia in an acidosis state. Clinicians should consider comprehensive clinical assessment, laboratory evaluation, and ECG monitoring to distinguish BrP from congenital BrS, especially in critically ill patients.
EFFICACY OF DIETARY SUPPLEMENTATION OF AMBON BANANA MIDRIB SIMPLICIA TO ENHANCE GROWTH PERFORMANCE, HEMATOLOGICAL PROFILE, IMMUNITY, AND SURVIVAL OF CATFISH CHALLENGED WITH Edwardsiella tarda Wahjuningrum, Dinamella; Nugroho, Riyanto; Yuhana, Munti; Citarasu, Thavasimuthu; Abdullah, Taufiq
Jurnal Riset Akuakultur Vol 20, No 3 (2025): September (2025)
Publisher : Politeknik Kelautan dan Perikanan Jembrana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/jra.20.3.2025.229-244

Abstract

Catfish (Clarias sp.) is a significant aquaculture species, but its production is often limited by Edwardsiella tarda infections, which cause substantial losses. Plant-derived alternatives such as banana midrib simplicia offer promising solutions to enhance fish health and reduce antibiotic dependence. This study investigated the effects of Ambon banana (Musa paradisiaca var. sapientum) midrib simplicia on growth performance, hematological parameters, immune responses, and resistance to E. tarda infection in catfish. A completely randomized design was used with five treatments and three replications, consisting of a positive control, a negative control, and commercial feed supplemented with 2% (B2), 3% (B3), and 4% (B4) banana midrib simplicia. The feeding trial lasted 30 days, after which fish were intramuscularly injected with E. tarda (10⁷ CFU mL⁻¹). Growth performance, hematological indicators (red blood cell count, hemoglobin concentration, hematocrit, and white blood cell count), immune responses (phagocytic and respiratory burst activities), and survival rate were evaluated. Dietary supplementation with banana midrib simplicia significantly improved growth performance, hematological parameters, immune responses, and survival in catfish challenged with E. tarda compared to the control groups. The optimal supplementation dose was 3%, providing the most significant improvement in growth, immunity, and survival. These findings highlight the potential of banana midrib as a functional feed additive derived from agricultural by-products to promote fish health and aquaculture productivity. Ikan lele (Clarias sp.) merupakan salah satu komoditas penting dalam akuakultur, namun produksinya sering terkendala oleh infeksi Edwardsiella tarda yang menyebabkan kerugian signifikan. Alternatif berbasis tanaman seperti simplisia pelepah pisang menawarkan solusi potensial untuk meningkatkan kesehatan ikan dan mengurangi ketergantungan terhadap antibiotik. Penelitian ini mengevaluasi pengaruh simplisia pelepah pisang Ambon (Musa paradisiaca var. sapientum) terhadap kinerja pertumbuhan, parameter hematologis, respons imun, dan ketahanan terhadap infeksi E. tarda pada ikan lele. Penelitian ini menggunakan rancangan acak lengkap dengan lima perlakuan dan tiga ulangan, terdiri atas kontrol positif, kontrol negatif, serta pakan komersial yang disuplementasi simplisia pelepah pisang pada dosis 2% (B2), 3% (B3), dan 4% (B4). Uji pemberian pakan dilakukan selama 30 hari, kemudian ikan diinjeksi intramuskular dengan E. tarda (10⁷ CFU mL⁻¹). Parameter yang diamati meliputi pertumbuhan, indikator hematologis (jumlah eritrosit, konsentrasi hemoglobin, hematokrit, dan jumlah leukosit), respons imun (aktivitas fagositosis dan respiratory burst), serta tingkat kelangsungan hidup. Suplementasi pakan dengan simplisia pelepah pisang secara signifikan meningkatkan performa pertumbuhan, parameter hematologis, respons imun, dan kelangsungan hidup ikan lele yang diinfeksi E. tarda dibanding kelompok kontrol. Dosis optimal diperoleh pada suplementasi 3%, yang memberikan peningkatan terbesar pada pertumbuhan, imunitas, dan kelangsungan hidup. Temuan ini menunjukkan bahwa simplisia pelepah pisang memiliki potensi sebagai aditif pakan fungsional berbasis limbah pertanian untuk meningkatkan kesehatan ikan dan produktivitas akuakultur.
Co-Authors Abduh, Arif Maulana Abdullah, Anggi Prilya Ambarwati, Dewi Aris, Muhammad Aufa, In'amul Citarasu, Thavasimuthu Darise, Fatria Siti Maharani Darsan, Ismi Musdalifah Dinamella Wahjuningrum Fadhila, Audri Shabrina Fitriyani, Insan Haedar, Ali Harun, Afriliyanti Imowanto, Yuddy Irzal Effendi Johan, Willy Juharni, . Khoirul Umam Kinanda, Erka Wahyu Kumalasari, Ditta Putri Kurnia Agesti, Elmira M Igirisa, Siti Ariyati Mulyani, Ria Suci Muntahar, Waisya Ade MUNTI YUHANA Nua, Kristian Emanuel Nugroho, Riyanto Pardede, Maria Agustina Pradnyani, IGA Indah Prasetyadjati, Ari Prastio, Yuli Pribadi, Unggul Puspita Sari, Putri Putra, Rico Wicaksana Ramadhina, Erina Tri Riyadi Subur, Riyadi Rizkiyanti, Ita Setyawan, Ungky Agus Shavika Miranti Sri Nuryati Sri Wahyuni Suryanto Suryanto Taher, Muhammad Nur Tamrin Tamrin Triyuliarto, Dwiwardoyo Wahidin, Nurhalis Wange, Alisa Wulandari, Tri Laela Yasir, Fatah Abdul Zaelani, Muhammad Azis Zaiyanah, Munsifah