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All Journal HAYATI Journal of Biosciences Jurnal Teknologi Industri Pertanian Indonesian Journal of Biotechnology Journal of Agromedicine and Medical Sciences Journal of Tropical Biodiversity and Biotechnology Manajemen Pendidikan BERITA BIOLOGI JURNAL BIOLOGI INDONESIA Jurnal Teknologi Laboratorium Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) Chimica et Natura Acta Indonesian Journal of Chemistry Jurnal Sinergitas PkM & CSR FaST : Jurnal Sains dan Teknologi Walisongo Journal of Chemistry Menara Perkebunan Jurnal Teknik Informatika (JUTIF) Bioinformatics and Biomedical Research Journal Cermin Dunia Kedokteran Indonesian Journal of Life Sciences Makara Journal of Science Makara Journal of Technology Biosaintifika: Journal of Biology & Biology Education Jurnal Bioteknologi & Biosains Indonesia (JBBI) Cermin Dunia Kedokteran Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal) Jurnal Bioteknologi & Biosains Indonesia Berita Biologi
Arli Aditya Parikesit
Department Of Bioinformatics, School Of Life Sciences, Indonesia International Institute For Life Sciences (i3l), Jakarta, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Menara Perkebunan

 1 
Pemanfaatan bioinformatika dalam bidang pertanian dan kesehatan (The utilization of bioinformatics in the field of agriculture and health) Arli Aditya PARIKESIT; Dito ANUROGO; Riza A PUTRANTO
E-Journal Menara Perkebunan Vol 85, No 2 (2017): Oktober 2017
Publisher : INDONESIAN RESEARCH INSTITUTE FOR BIOTECHNOLOGY AND BIOINDUSTRY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22302/iribb.jur.mp.v85i2.237

Abstract

Bioinformatics can be used to manage the data storage resulted from in silico molecular biology experiments. Off-network (offline) applications require large computing resources, in which researchers in the bioinformatics field of agriculture and health sectors do not necessarily possess. This review paper addressed examples of affordable and applicable in silico analytical cases in both mentioned sectors. Genome sequence analysis and in silico drug design using (1) a computational method, pharmacokinetic parameter prediction, (2) Computer Aided Design and Drafting (CADD) technology, (3) potential protein action prediction, (4) OMICs application in stem cell biology, and (5) lncRNAs based database computing internet sites is one of examples. In agriculture, bioinformatics-based research has been used in (1) the development of molecular markers; (2) the design of primer for differential gene expression analysis; (3) the development of genetic maps; and (4) gene expression analysis. Further application of bioinformatics also targets the design of applicative products for pest control and the protection of plant varieties in the farm. Through this example, novice researchers in the bioinformatics field of agriculture and health sectors can conduct sophisticated research using standard computer tools, internet networks, and sufficient knowledge about bioinformatics. On the other hand, multidisciplinary collaboration between these scientists can be carried out through social networking. The synergy can be directed to improve computing capabilities and data analysis via procurement of computing resources and use of public information clusters. [Key words: genome sequences, in silico drug design, online, bioinformatics, health, agriculture.] AbstrakBioinformatika dapat digunakan dalam manajemen informasi di bidang penyimpanan data in silico dari eksperimen biologi molekuler. Aplikasi luar jaringan (luring) memerlukan sumber daya komputasi yang besar, yang belum tentu dimiliki oleh para peneliti dalam bidang bioinformatika kesehatan dan pertanian. Kajian ilmiah ini membahas contoh kasus analisis in silico yang terjangkau dan aplikatif dalam bidang kesehatan dan pertanian. Contoh kasus tersebut adalah analisis sekuen genom dan desain obat in silico, menggunakan pendekatan metode komputasional, prediksi parameter farmakokinetik, teknologi Computer Aided Design and Drafting (CADD), prediksi potensial aksi protein, aplikasi OMICs pada biologi sel punca, hingga komputasi basis data lncRNAs berbasis situs internet. Pada bidang pertanian, penelitian berbasis bioinformatika telah digunakan dalam (1) pengembangan penanda molekuler; (2) desain primer untuk analisis ekspresi gen diferensial; (3) pengembangan peta genetik; dan (4) analisis ekspresi gen. Pemanfaatan bio-informatika dalam ilmu terapan dibidang pertanian juga menyasar desain produk aplikatif untuk pengendalian hama dan perlindungan varietas tanaman. Melalui contoh tersebut, peneliti pemula dibidang bioinformatika kesehatan dan pertanian dapat melakukan penelitian canggih hanya dengan alat komputer standar, jaringan internet, dan pengetahuan mencukupi tentang bioinformatika. Disisi lain, sinergi dan kolaborasi antar peneliti multi-displiner dapat dilakukan melalui penggunaan jejaring sosial. Sinergi tersebut dapat diarahkan untuk meningkatkan kemampuan komputasi dan analisis data melalui pengadaan sumber daya komputasi dan penggunaan klaster informatika publik.[Kata kunci: sekuen genom, desain obat in silico, daring, bioinformatika, kesehatan, pertanian]
Pemanfaatan bioinformatika dalam bidang pertanian dan kesehatan (The utilization of bioinformatics in the field of agriculture and health) Arli Aditya PARIKESIT; Dito ANUROGO; Riza A PUTRANTO
Menara Perkebunan Vol. 85 No. 2 (2017): 85 (2), 2017
Publisher : INDONESIAN OIL PALM RESEARCH INSTITUTE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22302/iribb.jur.mp.v85i2.237

Abstract

Bioinformatics can be used to manage the data storage resulted from in silico molecular biology experiments. Off-network (offline) applications require large computing resources, in which researchers in the bioinformatics field of agriculture and health sectors do not necessarily possess. This review paper addressed examples of affordable and applicable in silico analytical cases in both mentioned sectors. Genome sequence analysis and in silico drug design using (1) a computational method, pharmacokinetic parameter prediction, (2) Computer Aided Design and Drafting (CADD) technology, (3) potential protein action prediction, (4) OMICs application in stem cell biology, and (5) lncRNAs based database computing internet sites is one of examples. In agriculture, bioinformatics-based research has been used in (1) the development of molecular markers; (2) the design of primer for differential gene expression analysis; (3) the development of genetic maps; and (4) gene expression analysis. Further application of bioinformatics also targets the design of applicative products for pest control and the protection of plant varieties in the farm. Through this example, novice researchers in the bioinformatics field of agriculture and health sectors can conduct sophisticated research using standard computer tools, internet networks, and sufficient knowledge about bioinformatics. On the other hand, multidisciplinary collaboration between these scientists can be carried out through social networking. The synergy can be directed to improve computing capabilities and data analysis via procurement of computing resources and use of public information clusters. [Key words: genome sequences, in silico drug design, online, bioinformatics, health, agriculture.] AbstrakBioinformatika dapat digunakan dalam manajemen informasi di bidang penyimpanan data in silico dari eksperimen biologi molekuler. Aplikasi luar jaringan (luring) memerlukan sumber daya komputasi yang besar, yang belum tentu dimiliki oleh para peneliti dalam bidang bioinformatika kesehatan dan pertanian. Kajian ilmiah ini membahas contoh kasus analisis in silico yang terjangkau dan aplikatif dalam bidang kesehatan dan pertanian. Contoh kasus tersebut adalah analisis sekuen genom dan desain obat in silico, menggunakan pendekatan metode komputasional, prediksi parameter farmakokinetik, teknologi Computer Aided Design and Drafting (CADD), prediksi potensial aksi protein, aplikasi OMICs pada biologi sel punca, hingga komputasi basis data lncRNAs berbasis situs internet. Pada bidang pertanian, penelitian berbasis bioinformatika telah digunakan dalam (1) pengembangan penanda molekuler; (2) desain primer untuk analisis ekspresi gen diferensial; (3) pengembangan peta genetik; dan (4) analisis ekspresi gen. Pemanfaatan bio-informatika dalam ilmu terapan dibidang pertanian juga menyasar desain produk aplikatif untuk pengendalian hama dan perlindungan varietas tanaman. Melalui contoh tersebut, peneliti pemula dibidang bioinformatika kesehatan dan pertanian dapat melakukan penelitian canggih hanya dengan alat komputer standar, jaringan internet, dan pengetahuan mencukupi tentang bioinformatika. Disisi lain, sinergi dan kolaborasi antar peneliti multi-displiner dapat dilakukan melalui penggunaan jejaring sosial. Sinergi tersebut dapat diarahkan untuk meningkatkan kemampuan komputasi dan analisis data melalui pengadaan sumber daya komputasi dan penggunaan klaster informatika publik.[Kata kunci: sekuen genom, desain obat in silico, daring, bioinformatika, kesehatan, pertanian]
Co-Authors Adi Sofyan Ansori, Muhammad Albert Widjaja Aldino Hafidzhah, Muhammad Alhussain, Shaheer Alyaa Farrah Dibha Angelique, Priscilla Arif Nur Muhammad Ansori Bernard, Stefanus Bhat, Nausheen Burkov, Pavel Chandra, Nelson David Agustriawan Dedy Sugiono Deidre Valeska, Margareta Derkho, Marina Dian, Farida Aryani Didik Huswo Utomo Dito Anurogo Dito ANUROGO Dito Anurogo Dito Anurogo Dito Anurogo Dito Anurogo Dito Anurogo, Dito Ema Utami Ezra Bernandus Wijaya Fugaha, Daniel Ryan Gabriela, Vania Gabriele Mustika Kresnia Gabriella Patricia Adisurja Hafidzhah, Muhammad Aldino Heerlie, Devita Mayanda Herdiansyah, Mochammad Aqilah Hutapea, Hotma Martogi Lorensi Imron Imron Jakhmola, Vikash Jeremias Ivan Josephine, Evalina Junaida Astina Karimah, Nihayatul Karimah, Nihayatul Kharisma, Viol Dhea KUSRINI Kusrini, Kusrini Maksim Rebezov Margareta Deidre Valeska Margaretha, Febrina Maria Kiseleva Maulani Wijaya, Renadya Miko Wahyono, Tri Yunis Muhammad Aldino Hafidzhah Muhammad Aldino Handzhah Muhammad Hermawan Widyananda Murtadlo, Ahmad Affan Ali Nadezhda Kenijz Natalia Satya, Putri Gabriella Angel Nelda Aprilia Salim Nihayatul Karimah Patricia Adisurja, Gabriella Patricia, Gabriella Posa, Gabrielle Ann Villar Prakoso, Muhammad Ja'far Pratama, Rico Alexander Putri Gabriella Angel Natalia Satya Rahadian Zainul Ramanto, Kevin Nathanael Ratnasari, Nanda Risqia Pradana Renadya Maulani Wijaya Ridarto, Afif Maulana Yusuf Riza A PUTRANTO Rizky Nurdiansyah Rizky, Wahyu Choirur Ryan Fugaha, Daniel Ryan Wijaya Ryan Wijaya, Ryan Satrio Wibowo Scherbakov, Pavel Sepiashvili, Ekaterina Shemuel, Josia Sofy Permana Sri Wahyuningsih Stefanus Bernard Sudaryo, Mondastri Korib Sugiono, Dedy Svetlana Artyukhova Tambunan, Usman Sumo Friend Teguh Hari Sucipto, Teguh Hari Theo A Tochary Tochary, Theo A. Usman Sumo Friend Tambunan Utomo, Didik Huswo Utomo, Didik Huswo Vikash Jakhmola Viol Dhea Kharisma Wicaksono, Adhityo Wijaya, Renadya Maulani Yanuargi, Bayu Yulia Matrosova