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All Journal Public Health of Indonesia International Journal of Applied Biology Medical Laboratory Technology Journal Jurnal Endurance: Kajian Ilmiah Problema Kesehatan INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Health Information : Jurnal Penelitian Borneo Journal of Medical Laboratory Technology Jurnal Teknologi Kesehatan Molucca Medica Mestaka: Jurnal Pengabdian Kepada Masyarakat Jurnal Inovasi, Pemberdayaan dan Pengabdian Masyarakat Media Penelitian dan Pengembangan Kesehatan
Reni Yunus, Reni
Department Of Nursing, Polytechnic Of Health Kendari, Southeast Sulawesi, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Factors related to the presence of mosquito eggs trapped in ovitraps DHF-endemic areas in Kendari City, Indonesia Askrening, Askrening; Supryatno, Adi; Yunus, Reni; Supiati, Supiati
Public Health of Indonesia Vol. 7 No. 4 (2021): October - December
Publisher : YCAB Publisher & IAKMI SULTRA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v7i4.445

Abstract

Background: Dengue hemorrhagic fever (DHF), one type of infectious disease caused by the dengue virus, is still becoming a public health problem in Indonesia. The high number of dengue cases in Indonesia, especially in Kendari City itself, is closely related to environmental conditions, especially when it is known that the city has entered the rainy season.Objective: This study aimed to identify and analyze the factors associated with the presence of mosquito eggs trapped in ovitraps DHF-endemic area in Kendari City, Indonesia.Methods: This study used an analytic observational approach with a cross-sectional design. The research sample in this study was 50 houses located in endemic areas of Kendari selected using simple random sampling. Data were collected by observation using a checklist sheet and direct observation in each room of the respondent's house based on lighting, temperature, humidity, and physical environmental conditions, as well as the presence of mosquito eggs or larvae trapped in the ovitrap. The analysis was carried out in two stages, namely univariate analysis and bivariate analysis using the Chi-Square test.Result: From 50 houses observed, 13 houses (26%) had the presence of mosquito eggs, 42 houses (84%) had bad air temperature, 19 houses (38%) had poor humidity, and 35 houses (70%) had a higher frequency. In addition, the temperature, lighting, and environmental conditions did not have a significant relationship with the presence of mosquito eggs in ovitraps in endemic areas of Kendari City, with p-values of 0.94, 0.52, and 0.39, respectively. In contrast, the humidity factor has a significant relationship with the presence of eggs with a p-value of 0.000.Conclusion: There was a significant relationship between humidity and the presence of mosquito eggs in ovitraps in endemic areas of Kendari City, Indonesia. It is recommended that residents increase Mosquito Nest Eradication (PSN) activities, perform selective abatization, and disseminate information about DHF through counseling or other activities conveyed through health workers with full support from community leaders and adjusted to the level of education of the local population.
Hubungan Kebiasaan Merawat Gigi Dan Mulut Dengan Kejadian Karies Gigi Pada Siswa SD Negeri 09 Poasia Kota Kendari Mongan, Ruth; Yunus, Reni; Nurhayani, St.
Health Information : Jurnal Penelitian Digitalisasi Versi Cetak
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v7i1.536

Abstract

Hubungan Kebiasaan Merawat Gigi Dan Mulut Dengan Kejadian Karies Gigi Pada Siswa SD Negeri 09 Poasia Kota Kendari.
Fungsi Antioksidan dalam Menghambat Peroksidasi Lipid dan Meningkatkan Ketahanan Membran Eritrosit pada Penderita Diabetes Melitus Hasan, Fonnie Esther; Yunus, Reni
Health Information : Jurnal Penelitian Vol 15 No 2 (2023): Mei-Agustus
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v15i2.901

Abstract

Diabetes melitus (DM) merupakan penyakit kronis yang berakar pada defisiensi insulin, menyebabkan gangguan metabolik dan komplikasi mikro- dan makrovaskular. Hiperglikemia pada DM memicu stres oksidatif dengan peningkatan produksi radikal bebas, merusak vaskular melalui aktivasi jalur diasilgliserol/protein kinase C dan peningkatan aktivitas polyol pathway. Dampak stres oksidatif termanifestasi dalam perubahan komposisi lipid pada membran eritrosit, meningkatkan resistensi aliran mikrovaskular, dan menghasilkan malondialdehyde (MDA) sebagai biomarker stres oksidatif. Sistem proteksi terhadap radikal bebas melibatkan enzim dan antioksidan non-enzimatik, yang bekerja bersama untuk menetralkan efek merusak radikal bebas. Pemahaman mendalam tentang interaksi ini membuka peluang untuk pengembangan strategi pencegahan dan penanganan komplikasi DM secara lebih efektif melalui penelitian lanjutan.
Diabetes Mellitus and Bacterial Infections: A Review of Main Infections in DM Patients Yunus, Reni; Wijayati, Fitri; Askrening, Askrening; Rahayu, Dian Yuniar Syanti; Hasan, Fonnie E; Trees, Trees; Fusvita, Angriani
Public Health of Indonesia Vol. 10 No. 1 (2024): January - March
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v10i1.777

Abstract

Millions of single-celled microscopic organism called bacteria reside within the human body. Numerous infectious diseases in humans are caused by some of these pathogen bacteria. One of the major risk factors for bacterial infections is diabetes mellitus. Bacterial infections and diabetes may have a reciprocal relationship in which some illnesses exacerbate insulin resistance. Diabetes may occur as a result of bacteria in the digestive system. Any organ in a human body can become infected by bacteria. The respiratory tract, gastrointestinal tract, urinary tract, skin, and soft tissues are the most frequently infected areas with diabetes. Uncontrolled hyperglycemia increases the risk of bacterial infections by impairing innate and adaptive immune responses. Furthermore, skin ulceration can result from long-term diabetic consequences such peripheral vascular disease and neuropathy (sensorimotor and autonomic). These conditions can also lead to secondary bacterial infections.
Edukasi Pencegahan Penyakit Diare Dan Screening Sumber Air Minum Warga Di Wilayah Kecamatan Morosi Yunus, Reni; Hasan, Aswiro; Fauzi, Ahmad Zil
MESTAKA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 6 (2024): Desember 2024
Publisher : Pakis Journal Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58184/mestaka.v3i6.490

Abstract

Diarrhea cases are related to human behavior, clean water facilities, waste water disposal facilities and environmental health. The area in Morosi District is an area where the supply of clean water is still minimal and is an area close to the Morosi industrial area. Education is needed so that people can know the importance of drinking clean water to avoid diarrhea. The activity began with the distribution of questionnaires for a pre-test to measure the public's knowledge about diarrhea and the risk of contamination of drinking water sources. Then it continues with counseling or providing education, distributing leaflets and ending with a post test related to diarrhea and its prevention. Screening activities for the risk of contamination of drinking water sources for residents in Paku Village, Morosi District were carried out using the observation method using a sanitation inspection form. Educational activities regarding Diarrhea and its Prevention were carried out on September 5 2024 in Paku Village, Morosi District, Konawe Regency. Education regarding diarrhea and its prevention is very important in increasing the knowledge of the people of Paku Village, Konawe Regency. The percentage increase in public knowledge after being given education about diarrhea was 48.8%.  Based on the screening results of 10 dug wells in Paku Village, there are 7 wells that are in the Meet the Requirements (MS) category, and there are 3 other wells that are in the Not Meet the Requirements (TMS) category.
Immunomodulatory activity of kersen leaf extract (Muntingia calabura) on diabetic rats: analysis of immune response Hasan, Fonnie Esther; Yunus, Reni; Magdalena, Magdalena
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 6 No 2 (2024): Promising and valuable research towards diagnosis, prognosis and treatment of dis
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v6i2.5746

Abstract

The immune response to high blood glucose levels leads to an inflammatory response and also produces inflammation mediators. Immunomodulatory functions of Kersen (Muntingia calabura) need further enhancement to ensure that its benefits are more widely recognized by the public. This study aims to determine the immunomodulatory activity of Kersen leaf in inducing and modulating the immune response in diabetic rats. This study was an experimental laboratory with a pre-and post-test with a control group design. The subjects were 30 white rats (Rattus Novergicus Wistar Strain), were treated with extract M. calabura dose 1 (100 mg/kg bw/day), dose 2 (200 mg/kg bw/day), dose 3 (300 mg/kg bw/day). For clinical evaluation, three control groups were formed, including a Normal Control Group, a Diabetes Mellitus (DM) Positive Group, and a DM Positive Group treated with Anti-Diabetic Drugs. The highest amount of IFN-γ concentrations were found in the DM positive control group + antidiabetic drugs (710.3 ± 27.2 ng/mL).  The highest number of Nitrit Oxide (NO) concentration was found in the DM positive control group (103.7 ± 10.2 µmol/L). The highest average amount of pancreatic β cell regeneration was found in the normal control group.  The DM positive control group and the treatment group had a significant difference (p < 0.05) It means that there is a significant difference in the data of all treatment groups, or these three groups have anti-diabetic activity by repairing or preventing damage to the pancreas organ in DM rats. This study revealed that M. calabura possesses immunomodulatory activity, capable of inducing and modulating immune responses in diabetic rats.
Edukasi Pencegahan Penyakit Demam berdarah Dengue dan Optimalisasi Pemanfaatan Tanaman Berpotensi Penolak Vektor Penular DBD Yunus, Reni; Supiati, Supiati; Nurtimasiah, Wa Ode
Jurnal Inovasi, Pemberdayaan dan Pengabdian Masyarakat Vol 4 No 2 (2024): Juli- Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/jippm.v4i2.1535

Abstract

There are approximately 50 million cases of dengue fever every year, and 40% of the population is at risk of being infected with the dengue virus. Apart from utilizing government programs through the 3M program, dengue prevention measures can be taken by sowing larvicide. However, the use of chemical larvicides has disadvantages, such as repeated use of chemical larvicides carries the risk of contamination of pesticide residues in water, especially drinking water, and repeated use results in the emergence of resistance from various mosquito species. Research on plants with the potential to be larvicidal and repellent or mosquito repellents has proven that plants can be used as mosquito repellents, therefore it can eliminate the population level of the Aedes mosquito as a vector for transmitting dengue fever. The results of the research require to be introduced to the community,because indirectly reduce the occurrence of dengue fever cases in a village. The aim of this community service is to provide education to the public regarding Dengue Hemorrhagic Fever and information about plants that have the potential to repel mosquitoes as an effort to eliminate vectors that transmit dengue fever. This community service also aims to measure community knowledge about dengue hemorrhagic fever and its prevention. Educational activities regarding dengue hemorrhagic fever, prevention methods and socialization of plants that have the potential to repel dengue vectors were carried out on September 14 2023 in Taipa village, Lembo district, North Konawe district. In the education provided, it was seen that the participants were very active in asking questions about things they did not understand. The percentage increase in public knowledge regarding Dengue Hemorrhagic Fever after being given education was 76%.
EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura) MENINGKATKAN KETAHANAN MEMBRAN ERITROSIT TIKUS YANG DIPERLAKUKAN DIABETES MELLITUS Hasan, Fonnie Esther; Gobel, Sri Yunanci Van; Magdalena, Magdalena; Fristiohady, Adryan; Yunus, Reni
Media Penelitian dan Pengembangan Kesehatan Vol. 33 No. 2 (2023): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v33i2.1843

Abstract

The condition of Diabetes Mellitus (DM) due to hyperglycaemia can induce free radicals and decreased oxidant defence system, chronic hyperglycaemia will result in increased production of free radicals resulting in oxidative stress. The aim of this study was determine the oxidant activity of Kersen Leaf Extract in increasing the resistance of erythrocyte membranes in rats treated with diabetes mellitus by measuring the activity of Malondialdehyde (MDA) and measuring the percentage of erythrocyte cells that are hemolyzed. This study was conducted in vivo by examining the antioxidant activity of Muntingia calabura L. by measuring the levels of MDA and membrane resistance in diabetic rats. This study used animal model Rattus Norvegicus Wistar strain, total of 30 rats was divided into six groups with 5 rats in each group, which are negative control group, positive control group, positive control was added standard drug group, and diabetic rats. Kersen (Muntingia calabura L.) leaves extract reduced Malondialdehyde (MDA) levels of erythrocytes in diabetic rats at an optimum dose of 400 mg/kg of weight per day with a mean MDA value of 4.91 ± 2.1 µmol/ml. In addition, can reduce the amount of hemolysis of erythrocytes in diabetic rats at an optimum dose of 400 mg/kg of weight per day, and can reduce the number of abnormal erythrocytes in rats treated with diabetes mellitus with an optimum dose of 400 mg/kg bw/day with a mean haemolysis value of 33.34 ± 4.04%. Kersen (Muntingia calabura L) leaf extract increases the resistance of erythrocyte of diabetic rat’s.
PROFIL PENANDA FUNGSI HATI PADA PASIEN TUBERKULOSIS DI KOTA KENDARI Fauzi, Ahmad Zil; Yunus, Reni; Hasan, Fonnie Esther; Sari, Julianti Isma
Molucca Medica Vol 17 No 2 (2024): VOLUME 17, NOMOR 2, OKTOBER 2024
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/molmed.2024.v17.i2.124

Abstract

Tuberkulosis adalah penyakit pernapasan akut yang disebabkan oleh Mycobacterium tuberculosis yang dapat berdampak pada fungsi pernapasan. Penanganan penyakit tuberkulosis adalah dengan kepatuhan minum obat, akan tetapi masih ditemukan adanya kasus Multidrugs Resistensi Antibiotik yang diketahui dapat memberikan efek samping salah satunya hepatotoksik. Tujuan penelitian ini adalah untuk melakukan pemeriksaan penanda fungsi hati pada pasien tuberkulosis di Kota Kendari diantaranya bilirubin total, Serum Glutamic Oxaloacetic Tranaminase (SGOT) dan Serum Glutamic Piruvic Tranaminase (SGPT) dengan metode fotometri. Jenis penelitian ini adalah penelitian deskriptif kuantitaif dengan pendekatan cross sectional. Teknik sampling yang digunakan adalah purposive sampling, sesuai dengan kriteria sampel yang telah ditetapkan. Hasil penelitian menunjukkan terdapat 58 dari 60 subjek (97%) memiliki kadar bilirubin normal dengan rerata 0,41 mg/dl, 54 dari 60 subjek (90%) memiliki kadar SGOT normal dengan rerata kadar SGOT sebesar 21 IU/L dan 55 orang dari 60 subjek (92%) memiliki kadar SGPT normal dengan rerata kadar SGPT sebesar 17 IU/L.
Risk Microbiological Contamination in Well Water Around the Morosi Industrial Area, Southeast Sulawesi, Indonesia Yunus, Reni; Supiati, Supiati; Darmayani, Satya; Rafika, Rafika; Ihwan, Muh.; Triyaswati, Desty
Public Health of Indonesia Vol. 11 No. 3 (2025): July - September
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11i3.1057

Abstract

Background: Dug wells located near industrial areas have a higher contamination levels compared to wells far from industrial areas. Previous research has shown metal contamination in wells near industrial area. This gap highlights the need for further research that address the microbiological safety of water sources affected by industrial activities.Objectives: This study investigates the risk of microbiological contamination in well water surrounding the Morosi industrial area in Southeast Sulawesi, Indonesia.Methods: The type of research is quantitative observational design; this research analyzes 52 dug wells across four villages. Key variables examined include the distance of wells from septic tanks and the physical condition of the wells, assessed through microbiological testing using the Most Probable Number (MPN) method.Results: Majority of well samples (94.2%) did not meet microbiological quality standards, with a notable presence of E. coli in 44.2% of samples. Statistical analysis indicates a moderate relationship between the physical condition of wells and E. coli presence, as well as a significant association between proximity to septic tanks and contamination risk.Conclusion: There are various factors that contribute to the well’s contamination. Statistical analyses demonstrate the vulnerability of water sources around the Morosi industry to microbial contamination due to inadequate sanitation practices. Keywords: Microbiological contamination; dug well; Most Probable Number (MPN)
Co-Authors Afrindayanti Afrindayanti Angriani Fusvita Anita Rosanty, Anita Askrening Askrening Askrening Citranti, Elvia Darmayani, Satya Darmayani, Satya Fauzi, Ahmad Zil Fina Astina Fonnie E. Hasan Fristiohady, Adryan Gobel, Sri Yunanci Van Hasan, Aswiro Hasan, Fonnie E Hasan, Fonnie Esther Hasnah, Nur Ihwan, Muh. Ikbal Ikbal Jumasran, Jumasran Kartini Kartini Magdalena Magdalena Muh. Ikhsan, Muh. Muhammad Hilam Munanto, Risman Naningsih, Hasmia Nurhayani, St. NURHAYU MALIK, NURHAYU Nurtimasiah, Wa Ode Orno, Theosobia Grace Petrus Nugroho DS Puspita, Sarlita Putra, Ahmat Rediansya Rafika Rafika Rahayu, Dian Yuniar Syanti Ruth Mongan Ruth Mongan, Ruth Sari, Julianti Isma Satya Darmayani Supiati Supiati Supryatno, Adi Susilawati Trees, Trees Triyaswati, Desty Tuty Yuniarty Tuty yuniarty, Tuty Wijayati, Fitri