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Uji Zona Hambat Antibakteri Ekstrak Etanol Bunga Kamboja Cendana (Pulmeria alba L.) terhadap bakteri Escheria coli dan Staphylococcus aureus indriyani, dwi windi; novitarini, novitarini novitarini; Muhsin, Lalu Busyairi
Jurnal Ilmiah Pharmacy Vol 12, No 2 (2025)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v12i2.754

Abstract

Tingginya angka infeksi bakteri dan meningkatnya resistensi antibiotik memicu kebutuhan akan alternatif pengobatan berbasis herbal. Bunga kamboja cendana (Plumeria alba L.) diketahui memiliki kandungan senyawa bioaktif seperti flavonoid, alkaloid, tanin, dan saponin yang berpotensi sebagai antibakteri. Penelitian ini bertujuan untuk menguji zona hambat antibakteri ekstrak etanol bunga kamboja cendana terhadap bakteri Staphylococcus aureus dan Escherichia coli dengan variasi konsentrasi 25%, 50%, 75%, dan 100%. Metode yang digunakan adalah difusi sumuran dengan media Mueller Hinton Agar, serta dilakukan uji statistik Kruskal-Wallis dan Mann-Whitney. Hasil penelitian menunjukkan bahwa zona hambat terhadap Staphylococcus aureus dari ekstrak pekat adalah 14,9 mm, 16,3 mm, 17,1 mm, dan 17,5 mm, sedangkan terhadap Escherichia coli sebesar 7,6 mm, 9,1 mm, 10,4 mm, dan 11,3 mm. Uji statistik menunjukkan hasil signifikan (p = 0,000) pada kedua jenis bakteri, menandakan adanya perbedaan antar konsentrasi. Dapat disimpulkan ekstrak etanol bunga kamboja cendana memiliki zona hambat yang signifikan, terutama lebih efektif terhadap bakteri gram positif Staphylococcus aureus.Kata kunci: Antibakteri alami; Escherichia coli; Plumeria alba L; Staphylococcus aureus; Zona hambat.
Effect of gamal leaves (Gliricidia sepium ) extract against termite (Coptotermes curvignathus) Pratiwi, Baiq Yulia Hasni; Muhsin, Lalu Busyairi
Jurnal Pijar Mipa Vol. 18 No. 6 (2023): November 2023
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v18i6.5863

Abstract

The World Health Organization (WHO) estimates around 3 million people working in the agricultural sector experience insecticide poisoning, and 18 thousand of them die every year. The massive use of synthetic insecticides can harm non-targeted organisms such as plants and livestock. Moreover, this may lead to ecological imbalance and increase pollution. Thus, there is a need for innovation in making natural insecticides. Indonesia is home to abundant plant diversity; one of those is the Gamal plant (Gliricidia sepium). Previous studies found that Gamal leaves contain secondary metabolites such as flavonoids, alkaloids, tannins, saponins, and steroids. Flavonoids are known to have a toxic effect on mealybugs in the papaya plant, and tannins are antimicrobial and often used as pest control. Based on this, the Gamal plant has potential as a natural insecticide. One of the most critical pests in agriculture and households is termites (Coptotermes curvignathus), which often cause losses by damaging plants and household furniture. Also, there is no research yet on Gamal leaves against termites. Therefore, research is necessary to test the effectiveness of Gamal leaf extract against termites. In this study, experimental research was used with a quantitative approach. The Gamal leaf extract was obtained using ethanol and methanol solvents through a maceration technique. Several termites were acclimatized, and 120 were taken randomly for toxicity testing. Four concentrations (10%, 25%, 50%, and 75%) were applied to each group of ten termites. This treatment was repeated three times, and the termite mortality time was measured. Afterwards, the value of LC50 was determined using a regression line between log concentration and probit mortality. The result shows that the higher the concentration, the shorter the termite death time. The mortality rate reaches 100% within 1 to 2 minutes after treatment. The LC50 value of Gamal leaves extract against termites obtained is 5,1%. This indicates that Gamal leaves are very effective in killing termites, even in the lowest concentration. It is likely caused by secondary metabolites, especially flavonoids, that have insecticidal effects. In brief, the ethanolic and methanolic extract of Gamal leaves has the potential to be a natural insecticide to substitute synthetic insecticide, which is safer, economical, and environmentally friendly.
Edukasi Pemanfaatan Bahan Alam sebagai Asi Booster pada Ibu Hamil dan Menyusui Novitarini; Muhammad Eka Putra Ramandha; Baiq Yulia Hasni Pratiwi; Lalu Busyairi Muhsin; Mia Ariasti; Sri Winarni Sofya
Jurnal Ilmiah Pengabdian dan Inovasi Vol. 2 No. 4 (2024): Jurnal Ilmiah Pengabdian dan Inovasi (Juni)
Publisher : Insan Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57248/jilpi.v2i4.399

Abstract

Low levels of exclusive breastfeeding will increase the risk of stunting and susceptibility to disease in the future. One of the reasons for this low supply is that breast milk production is not smooth, so it is necessary to facilitate the production of breast milk from natural ingredients. This service aims to educate about using natural ingredients to enable breast milk for pregnant and breastfeeding mothers. This service method has 4 stages: namely approach, preparation, delivery of material, and discussion. The results of the service showed that the village community understood the natural ingredients that could be used to facilitate breast milk, namely katuk leaves, turi, spinach and banana blossoms. Apart from that, in the service, proper processing is demonstrated so that the content is not lost or reduced. The conclusion of this service is that the community of Preparation Reban Madani village will utilize natural ingredients with proper processing to facilitate breast milk so that they can carry out exclusive breastfeeding. The implication of community service is that village knows how to process local plants to facilitate breast milk.
Uji Kualitatif Kandungan Senyawa Sianida pada Tanaman dengan Metode Pikrat Khairani, Ayudia Cipta; Ariasti, Mia; Muhsin, Lalu Busyairi; Amrulloh, Lalu Sanik Wahyu Fadil; Martayuni, Ruprika Dwi
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 1 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i1.5047

Abstract

Indonesian people have traditionally utilized various local plants as alternative food sources. These plants are widely available and have considerable nutritional value; however, some of them are known to contain toxic compounds such as cyanide (HCN), which can be harmful to human health if not properly processed. Therefore, this study aimed to examine the presence of cyanide compounds in several of these commonly consumed plants. The research was conducted using a qualitative test based on the picrate method. The samples tested included cassava, cassava leaves, bamboo shoots, gadung tubers, and taro tubers. The findings indicated that all tested samples showed positive results for the presence of cyanide, as evidenced by the observed color change from yellow to reddish-brown. In conclusion, all five types of plant samples tested contained cyanide, emphasizing the importance of proper processing techniques to reduce toxicity levels before consumption by the public.
Tanaka and Cycling Test of Water Pumpkin Fruit Extract (Lagenaria siceraria (Molina) Standl.) as Natural Hair Tonic Spray Sofya, Sri Winarni; Muhsin, Lalu Busyairi
Jurnal Pijar Mipa Vol. 20 No. 8 (2025): Special Issue
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v20i8.10541

Abstract

Hair loss and slow hair growth remain common cosmetic concerns, while prolonged use of synthetic hair growth agents may pose safety and sustainability issues. This study aimed to investigate the effectiveness and stability of a natural hair tonic spray formulated from water pumpkin (Lagenaria siceraria (Molina) Standl.) fruit extract. The extract was prepared using ethanol maceration and incorporated into three formulations with concentrations of 5%, 10%, and 15%. Effectiveness was assessed through a Tanaka hair growth test on rabbits for 21 days, while stability was evaluated through a 28-day cycling test, involving alternating temperature cycles (2–8°C, 25°C, and 40°C). The results indicated that all formulations exhibited stable organoleptic characteristics, pH, and homogeneity throughout storage. The F3 formula (15%) demonstrated the highest hair growth activity (2.4 cm average length), comparable to the positive control (2.7 cm). The enhanced hair growth effect is attributed to flavonoids and saponins that improve microcirculation around follicles and stimulate keratinocyte proliferation. This research highlights the potential of water pumpkin fruit extract as a sustainable and cost-effective natural alternative to synthetic hair growth agents. Future studies should explore optimization of formulation stability and molecular mechanisms underlying follicular activation.
Pemberdayaan Ekonomi Desa Sigar Penjalin melalui Inovasi Sabun Ketapang dan Digitalisasi Wisata Komunitas Patty, Elyakim Nova Supriyedi; Sahdan Saputra; Lalu Busyairi Muhsin; Erin Ryantin Gunawan; Diswandi
Jurnal Pengabdian Pada Masyarakat IPTEKS Vol. 3 No. 1 (2025): Jurnal Pengabdian Pada Masyarakat IPTEKS, Desember 2025
Publisher : CV. Global Cendekia Inti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71094/jppmi.v3i1.181

Abstract

This community service program aimed to enhance the economic empowerment of the Sigar Penjalin Village community through the innovation of ketapang (Terminalia catappa) leaf-based soap and the digitalization of community-based tourism. The program employed a Participatory Action Research (PAR) approach, actively involving local stakeholders in the stages of problem identification, planning, implementation, and evaluation. The activities included training on the formulation and production of herbal soap, product packaging and branding, as well as capacity building in digital marketing through social media platforms. The results indicated a significant improvement in community skills related to value-added product development and digital promotion strategies. Furthermore, the initiative contributed to diversifying local income sources and reducing dependency on traditional economic sectors. The integration of local natural resources with digital technology fostered greater community awareness, participation, and sustainability in economic development. Overall, this program demonstrates that combining local resource innovation with digital transformation can serve as an effective strategy for strengthening rural economies and promoting community resilience.
Safety and termiticidal efficacy of gliricidia sepium leaf extract: dermal irritation and toxicity againts Coptotermes curvignathus Lalu Busyairi Muhsin; Nurul Indriani
Acta Chimica Asiana Vol. 9 No. 1 (2026)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v9i1.254

Abstract

The overuse of synthetic insecticides in agriculture and household pest control raises concerns regarding health risks, environmental toxicity, and insect resistance. In Indonesia, about 15% of agricultural and plantation land is affected by pest infestations, with Coptotermes curvignathus recognized as one of the most destructive species due to its wood-boring activity. This study aimed to develop an eco-friendly insecticide using Gliricidia sepium leaf extract, which contains bioactive compounds such as steroids, tannins, and saponins with insecticidal potential. Four formulations were prepared with extract concentrations of 0 g (F0), 0.15 g (F1), 0.3 g (F2), and 0.45 g (F3) in 100 mL solvent. Physicochemical evaluations included pH measurement, stability observation, and homogeneity testing, while safety was assessed through dermal irritation tests on rabbits using the Draize method. Efficacy against termites was evaluated using probit analysis (IBM SPSS v22). Results showed that all formulations were physically stable, homogenous, and exhibited suitable pH values. Irritation testing revealed no erythema or edema, with primary irritation indices below 0.5, classifying the formulations as non-irritating even at low pH values. Insecticidal testing demonstrated complete termite mortality, with the F3 formulation showing the most rapid and potent effect. These findings indicate that G. sepium extract-based formulations are safe, effective, and environmentally friendly, supporting their potential as botanical insecticides to replace synthetic alternatives in sustainable pest management systems.