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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Nurse Media Journal of Nursing Jurnal Kedokteran Brawijaya Jurnal Kesehatan Mesencephalon Care : Jurnal Ilmiah Ilmu Kesehatan Narra J Scientica: Jurnal Ilmiah Sains dan Teknologi
Sri Poeranto, Sri
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PENGARUH TERAPI KOGNITIF TERHADAP PENINGKATAN HARGA DIRI REMAJA Effendi, Zulian; Poeranto, Sri; Supriati, Lilik
Jurnal Kesehatan Mesencephalon Vol 2, No 4 (2016)
Publisher : Jurnal Kesehatan Mesencephalon

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.308 KB)

Abstract

Abstrak: Kehidupan remaja di Lembaga Pembinaan Khusus Anak (LPKA) merupakan bentuk dari konsekuensi hukuman atas perilaku melanggar hukum yang pernah dilakukan. Berbagai permasalahan dialami remaja dalam menjalani kehidupannya di LPKA, diantaranya perubahan hidup, hilangnya kebebasan dan hak-hak yang semakin terbatas, hingga perolehan label “panjahat” yang melekat pada dirinya.Oleh sebab itu, dibutuhkan terapi untuk meningkatkan harga diri pada remaja. Penelitian ini bertujuan melihat pengaruh terapi kognitif terhadap peningkatan harga diri remaja di LPKA. Penelitian ini menggunakan desain Quasi Experimental Pre-Post Test with Control Group. Jumlah sampel sebanyak 28 responden yang terdiri dari 14 kelompok perlakuan dan 14 kelompok kontrol dengan teknik purposive sampling. Instrument pengukuran harga diri menggunakan kuesioner yang di modifikasi dari Roserberg Self-Esteem Scale. Hasil penelitian ini menunjukkan terdapat perbedaan peningkatan harga diri remaja antara sebelum dan sesudah diberikan terapi generalis HDR dan terapi kognitif pada kelompok perlakuan (nilai p-value = 0,000). Pada kelompok kontrol terdapat perbedaan peningkatan harga diri antara sebelum dan sesudah diberikan terapi generalis HDR (nilai p-value= 0,000), sedangkan untuk harga diri remaja sesudah diberikan intervensi antara kelompok perlakuan dengan kelompok kontrol terdapat perbedaan peningkatan harga diri antara kelompok perlakuan dengan kelompok kontrol setelah diberikan intervensi (nilai p-value =0,006).Pemberian terapi generalis dan terapi kognitif memiliki pengaruh yang lebih bermakna terhadap peningkatan harga diri remaja dibandingkan dengan pemberian tindakan generalis saja. Kata kunci: harga diri, terapi kognitif, remaja
ANALISIS KORELASI PENERIMAAN DENGAN HARGA DIRI ORANGTUA DAN STRES PENGASUHAN DALAM MERAWAT ANAK RETARDASI MENTAL Fitria, Yeni; Poeranto, Sri; Supriati, Lilik
Jurnal Kesehatan Mesencephalon Vol 2, No 4 (2016)
Publisher : Jurnal Kesehatan Mesencephalon

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Abstract

Abstrak : Kondisi anak dengan retardasi mental menjadi stresor tersendiri bagi orangtua karena gangguan kognitif dan fungsi adaptifnya menyebabkan perlunya penanganan khusus dalam berbagai hal. Hal tersebut dapat berdampak pada penerimaan orangtua terhadap anak dan harga diri orangtua yang pada akhirnya dapat memicu timbulnya stres pengasuhan. Penelitian ini bertujuan untuk menganalisis korelasi antara penerimaan orangtua dengan harga diri orangtua dan stres pengasuhan dalam merawat anak retardasi mental. Rancangan penelitian ini adalah analitik korelasi dengan pendekatan cross sectional. Teknik sampling menggunakan purposive sampling dengan jumlah 43 responden. Instrumen penelitian yang digunakan yaitu Parental Acceptance Rejection Questionnaire/ (PARQ), Brief Self esteem Inventory/ (BSEI) dan Parenting Stres Index Short Form/ (PSI-SF). Analisis statistik menggunakan uji korelasi pearson dan analisis jalur (path analysis). Analisis data menunjukkan bahwa ada hubungan antara penerimaan dengan harga diri orangtua (p= 0,001; r= 0,471; ρ= 0,471). Ada hubungan antara penerimaan orangtua dengan stres pengasuhan (p=0,000; r= -0,554; ρ= -0,383). Ada hubungan antara harga diri orangtua dengan stres pengasuhan (p= 0,000; r= -0,544; ρ= -0,364). Untuk meminimalkan stres pengasuhan dalam merawat anak retardasi mental, sebaiknya orangtua lebih meningkatkan penerimaan terhadap anak sehingga tidak memberikan tuntutan yang melebihi kemampuan anak. Selain itu orangtua perlu memiliki penilaian positif terhadap diri sendiri sehingga lebih mampu beradaptasi dengan stresor yang dialami. Kata Kunci: penerimaan orangtua, harga diri orangtua, stres pengasuhan, retardasi mental
Effects of Islamic Spiritual Mindfulness on Stress among Nursing Students Munif, Badrul; Poeranto, Sri; Utami, Yulian Wiji
Nurse Media Journal of Nursing Vol 9, No 1 (2019): (JUNE 2019)
Publisher : Department of Nursing, Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.587 KB) | DOI: 10.14710/nmjn.v9i1.22253

Abstract

Background: Academic stress is a major problem that often occurs in nursing students. Islamic spiritual mindfulness (ISM) is an adaptive coping strategy used to mitigate various negative psychological reactions to respond stressors experienced by the body to build self-awareness that any problems experienced today are the scenario of Allah.Purpose: This study aimed to determine the effects of Islamic spiritual mindfulness therapy to reduce stress.Methods: This study used a pre-post quasi-experimental design with a control group. Participants were bachelor students of nursing who are Muslim and experienced stress in working on the thesis (n=36) and were assigned to two groups: the experimental group receiving Islamic spiritual mindfulness and the control group. Data were collected using questionnaires of Depression Anxiety Stress Scale (DASS) and analyzed using paired t-test and unpaired t-test.  Results: The results showed that the mean stress level of students in the intervention group decreased from 20.6±2.97 to 11.4±5.81 after the intervention. Meanwhile, in the control group, the mean student stress level slightly decreased from 19.7±2.82 to 17.8±5.01. The t-test obtained a p-value of 0.001, indicating that there were significant differences in stress levels between the intervention group and the control group. The effect size obtained the value of 0.59, meaning the level of influence was in the medium category.Conclusion: This study concluded that Islamic spiritual mindfulness was effective in reducing stress among nursing students working on the thesis. It is recommended for the nursing profession, especially mental health nurses, to apply Islamic spiritual mindfulness therapy as one of the psychotherapy interventions.
Kombinasi Artesunat Injeksi dan Ekstrak Brotowali (Tinospora crispa (L) Miers) Menurunkan Derajat Parasitemia serta Meningkatkan Ekspresi HSP70 dan Endoglin pada Mencit C57BL/6J yang Diinfeksi Plasmodium berghei Swastomo, Rahadi; Budiarti, Niniek; Fitri, Loeki Enggar; Poeranto, Sri
Jurnal Kedokteran Brawijaya Vol 29, No. 4 (2017)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2017.029.04.3

Abstract

Penemuan kombinasi terapi baru untuk malaria dianggap penting karena kemampuan resistensi dari Plasmodium terhadap pengobatan terdahulu. Sebanyak 18 mencit dibagi ke dalam kelompok kontrol negatif, kontrol positif, kelompok artesunat, serta kelompok kombinasi artesunat dengan brotowali (dosis 50 mg, 60 mg dan 70 mg). Selain kontrol negatif, semua mencit diinfeksi Plasmodium berghei. Selanjutnya diamati derajat parasitemianya sampai hari ke-7, kemudian dilakukan pemeriksaaan imunohistokimia guna mengetahui ekspresi HSP70 dan endoglin pada otak mencit. Kombinasi artesunat injeksi dan ekstrak brotowali terbukti dapat menurunkan derajat parasitemia lebih baik dari pemberian terapi tunggal artesunat dan meningkatkan ekspresi HSP70 dan endoglin. Kesimpulannya, kombinasi terapi malaria menggunakan artesunat dan brotowali terbukti berpotensi sebagai terapi kombinasi yang efektif terhadap malaria karena mampu menurunkan derajat parasitemia sampai 0% dan meningkatkan ekspresi HSP70 dan endoglin pada otak mencit C57BL/6J secara signifikan. 
Growth Rate Differences of Chrysomya sp. Larvae on Rattus novergicus Wistar Strain Corpse Exposed and Unexposed to Ephedrine Toxic Dose Poeranto, Sri; Prastowo, Wening; Resmi, Diandra Laksmita; Nugraha, Rivo Yudhinata Brian
Journal of Tropical Life Science Vol 7, No 3 (2017)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.07.03.06

Abstract

Post Mortem Interval (PMI) is used as a parameter to define the onset, cause, manner, and time of death to help maintenance of law and identify crime victims by the age of the larvae found. Larval growth is influenced by the temperature, humidity, and contaminant (drug or toxic). This experiment used two media of dead rats (200 grams), one given ephedrine of LD50 = 266 mg/kg and the other without ephedrine. Both were put in 2 cages each containing 50 Chrysomya sp. Ten larvae were randomly taken every day for 14 days to be measured their length, weight, and duration of growth. The 3rd larvae stage in the media with ephedrine had weight gain on 5th – 6th day morning, while larvae in media without ephedrine had static weight gain on 5th day morning - afternoon and weight decrement on 6 – 7th day morning. Larva’s peak ratio of length/weight in the media with ephedrine was higher than that of larvae in the media without ephedrine. Larvae on media with ephedrine grew faster in 1st, 2nd, 3rd larvae stage, and pupal stage compared to larvae without ephedrine. Therefore, this study indicates that ephedrine can accelerate the growth rate of Chrysomya sp. larvae.
Vitamin D3 induces stem cell activation via Lgr5-Bmi1 expression and improving mouse colitis histology index Wibowo, Satrio; Pramadhani, Almira; Subandiyah, Krisni; Handono, Kusworini; Poeranto, Sri
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.430

Abstract

Conventional therapy for inflammatory bowel disease using long-term anti-inflammatory drugs does not seem to provide optimal results. Adjuvant therapy using vitamin D3 is believed to have an essential role in repairing the colonic mucosa through the activation of colonic stem cells. The aim of this study was to demonstrate the effect of vitamin D3 in mucosal repair through stem cell activation, marked by leucin-rich repeat-containing G protein-coupled receptor 5 (Lgr5) and B lymphoma Mo-MLV insertion region 1 (Bmi1) expression and decrease the mouse colitis histology index (MCHI) score. In this study, 50 Mus musculus strain BALB/c were divided into five groups: negative control group, colitis group, and colitis groups with vitamin D3 administration of 0.2 mcg, 0.4 mcg, and 0.6 mcg per 25 g body weight for seven days. Dextran sulfate sodium (DSS) 5% was used to induce colitis. Lgr5-Bmi1 expression was measured using immunodoublestain fluorescent labeling method. Our data suggested that administration of vitamin D3 significantly increased expression of Lgr5-Bmi1 in the colonic mucosa. The colitis group treated with the highest dose of vitamin D3 (0.6 mcg/25 gram) showed the lowest MCHI score (3.60±0.64) while the lowest dose of vitamin D3 had the highest MCHI score (12.60±1.47). In conclusion, stimulating stem cells, vitamin D3 administration stimulates mucosal regeneration, as demonstrated by upregulated expression of Lgr5-Bmi-1.
EFEK ANTIBAKTERI EKSTRAK DAUN PACAR AIR (Impatiens balsamina Linn) TERHADAP Staphylococcus aureus ISOLAT PUS SECARA IN VITRO Cahyaningtyas, Tita Dwi; Winarsih, Sri; Poeranto, Sri
Scientica: Jurnal Ilmiah Sains dan Teknologi Vol. 2 No. 8 (2024): Scientica: Jurnal Ilmiah Sains dan Teknologi
Publisher : Komunitas Menulis dan Meneliti (Kolibi)

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Abstract

Staphylococcus aureus merupakan bakteri flora normal yang dapat menyebabkan infeksi pada hampir seluruh bagian tubuh manusia. Saat ini, beberapa galur S.aureus diketahui telah resisten terhadap antibiotik akibat penggunaan antibiotik yang tidak sesuai dengan ketentuan. Pengembangan tanaman sebagai obat terus dilakukan. Daun Pacar Air (Impatiens balsamina Linn) mengandung senyawa yang diprediksi memiliki efek antibakteri yakni kumarin, flavonoid, dan saponin. Penelitian ini bertujuan untuk menguji efek antibakterial ekstrak daun Pacar Air terhadap Staphylococcus aureus. Sampel bakteri S.aureus adalah 4 isolat yang berasal dari spesimen pus dari 4 penderita. Uji antibakteri menggunakan metode dilusi agar dengan konsentrasi akhir ekstrak yang digunakan yaitu 0,2%; 0,4%; 0,6%; 0,8%; dan 1% v/v. Hasil penelitian menunjukkan bahwa KHM ekstrak daun Pacar Air terhadap S.aureus adalah 0,8% v/v. Uji Kruskall Wallis dan Mann Whitney menunjukkan terdapat perbedaan jumlah koloni bakteri yang signifikan pada perubahan konsentrasi ekstrak daun Pacar Air (Kruskall Wallis, p=0,000). Uji Korelasi Spearman menunjukkan adanya hubungan yang erat dan berbanding terbalik serta pengaruh yang signifikan antara konsentrasi ekstrak dengan jumlah koloni bakteri (Spearman, R = - 0,971; p=0,001). Kesimpulan dari penelitian ini adalah ekstrak daun Pacar Air memiliki efek antibakteri terhadap S.aureus secara in vitro dengan KHM 0,8% v/v.
Kombinasi Glucomannan Hydrolysates (Gmh) Dan Antibiotik Metronidazole Berpengaruh Terhadap Kadar Sitokin Il-23 Pada Bacterial Vaginosis Wanita Usia Subur Purwanti, Anik Sri; Sumarno, Sumarno; Rahardjo, Bambang; Winasih, Sri; Poeranto, Sri
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 7, No 1 (2019): EDITION MARCH 2019
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (736.765 KB) | DOI: 10.33366/jc.v7i1.1105

Abstract

Woman’s reproductive tract often has problems, especially in women of childbearing age. One of them is Bacterial Vaginosis is a clinical condition that occurs a lot. BV infection is a polymicrobial infection caused by a decrease in the amount of Lactobaclilus with anaerobic bacteria that increases excessively. Alternative treatment for BV is given by using the results hydrolysates of konjac plant extracted in dosage forms Glucomannan Hydrolysates (GMH) containing glucose and mannose prebiotic which can support the growth development of Lactobacillus in the vaginal mucosa. This study was to determine the effect of Glucomannan Hydrolisates (GMH) + Metronidazole on levels of IL 23 cytokines in BV of reproductive age women. The method of this study used the True Experimental design with the type of research The randomized pretest-posttest was in vivo. The subjects selected in this study design used Randomized techniques. A sample of 7 people WUS with BV given GMH 300mg + Metronidazole 1000 mg for 9 days of use, To assess the levels of cytokine IL 23 using the ELISA method. Data analysis using a ratio scale was analyzed using the metric statistical test, normality test using Shapiro-Wilk test and comparative test using Repeated Measure ANOVA. The overall results of the analysis showed that the combination of GMH and Antibiotics Metronidazole could significantly increase the levels of cytokine IL 23 compared to other therapies to treat bacterial vaginosis in women of childbearing age
Co-Authors Anik Sri Purwanti Bambang Rahardjo Cahyaningtyas, Tita Dwi Fitriana, Nurul Fatwati Krisni Subandiyah Kusworini Handono Lilik Supriati, Lilik Loeki Enggar Fitri Mukhamad Nooryanto, Mukhamad Munif, Badrul Niniek Budiarti B Nugraha, Rivo Yudhinata Brian Pramadhani, Almira Resmi, Diandra Laksmita Satrio Wibowo Sri Winarsih Sumarno . Swastomo, Rahadi Tina Handayani Nasution Wening Prastowo Winasih, Sri Yayuk Eliyana . Yeni Fitria Yulian Wiji Utami Zulian Effendi