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Yulian Wiji Utami
Universitas Brawijaya
Computer Science & IT Economics, Econometrics & Finance Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Efektifitas Hidrogel Binahong (Anredera cordifolia (Ten.) Steenis) terhadap Penurunan Jumlah Makrofag pada Penyembuhan Luka Fase Proliferasi Tikus Putih (Rattus norvegicus) Galur Wistar Kondisi Hiperglikemia PI, Gadis Mutiara; Nurdiana, Nurdiana; Utami, Yulian Wiji
Majalah Kesehatan FKUB Vol 2, No 1 (2015)
Publisher : Faculty of Medicine Universitas Brawijaya

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Abstract

Hiperglikemia adalah kondisi kadar gula darah ≥ 126 mg/dl yang menyulitkan penyembuhan luka. Kandungan daun binahong berupa saponin, flavonoid, polifenol, triterpenoid, antosianin, asam ursolat dan karbonat diduga dapat membantu mempercepat proses penyembuhan luka. Makrofag sebagai sel yang memfagosit daerah luka dan membersihkan debris akan meningkat pada fase inflamasi dan akan menurun jumlahnya pada fase proliferasi ketika luka mulai menutup.  Tujuan penelitian ini adalah untuk mengetahui pengaruh perawatan luka kondisi hiperglikemia menggunakan hidrogel binahong terhadap jumlah makrofag. Desain penelitian adalah true experiment dengan metode randomized posttest only controlled group design dilakukan terhadap hewan coba tikus putih jantan galur Wistar. Jumlah sampel adalah 30 tikus (n = 5) dan dibagi dalam 6 kelompok yaitu 4 kelompok perlakuan yaitu menggunakan basis hidrogel, hidrogel binahong konsentrasi 2,5 %, 5 %, 7,5 %, dan 2 kelompok kontrol normal saline (NS) pada tikus kondisi sehat dan kondisi hiperglikemia. Data yang diukur adalah jumlah makrofag pasca perawatan luka selama 12 hari. Analisis uji one-way ANOVA didapatkan  p = 0,000 (p < 0,05). Melalui uji post hoc test hidrogel binahong 5 % memiliki perbedaan signifikan (p < 0,05) dengan K (-) NS (p = 0,004), K (+) NS (p = 0,000), basis hidrogel (p = 0,001), hidrogel binahong 2,5 % (p = 0,018). Dapat disimpulkan bahwa perawatan luka menggunakan hidrogel binahong dapat menurunkan jumlah makrofag pada penyembuhan luka fase proliferasi di jaringan kulit luka tikus dengan kondisi hiperglikemia. Kata kunci: Hiperglikemia, Hidrogel binahong, Jumlah makrofag.
Studi Komparasi Media Kultur Coco Blood Malachite Green (CBM) dengan Lowenstein Jensen (LJ) untuk Diagnosis Cepat, Spesifik, dan Sensitif pada Sputum Pasien Suspek Tuberkulosis Munawaroh, Anisful Lailil; N.H, Dwi Yuni; Utami, Yulian Wiji
Majalah Kesehatan FKUB Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Brawijaya

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Abstract

Di Indonesia, TB merupakan permasalahan kesehatan utama, bahkan masuk ke dalam 10 negara dengan beban TB terbanyak di dunia. Diagnosis laboratorium penyakit TB masih menjadi permasalahan yang penting di Indonesia. Media biakan yang menjadi gold standard untuk menegakkan diagnosis TB adalah media lowensten-jensen (LJ). Akan tetapi, metode ini memerlukan inkubasi yang lama yaitu sekitar 8 minggu setelah waktu inokulasi. Untuk meminimalkan risiko penularan lebih luas dan perjalanan penyakit yang lebih berat, diagnostik TB memerlukan medium biakan yang lebih cepat. Coco blood malachite green (CBM) merupakan inovasi media kultur yang memiliki komposisi air kelapa muda, malachite green, darah domba, agar darah, dan gliserol. Air kelapa merupakan cairan yang kaya nutrisi dan steril, malachite green memiliki sifat bakteriostatik, hal ini memiliki efek positif dalam mencegah adanya kontaminan dalam media kultur CBM. Agar darah mengandung protein, lemak, karbohidrat serta elemen nutrisi penting yang dapat mempercepat pertumbuhan dari beberapa jenis bakteri termasuk Mycobacterium. Darah domba mengandung protein hematin sebagai sumber nutrisi bakteri. Gliserol sebagai sumber karbon. Penelitian ini merupakan eksperimental murni post test only control group design dengan 31 sampel sputum penderita suspek tuberkulosis yang di inokulasi pada 31 media CBM dan 31 media LJ sebagai kontrol positif. Pengamatan makroskopis dilakukan maksimal 8 minggu, pertumbuhan koloni dikonfirmasi dengan pengecatan BTA. Hasil uji Mann Whitney didapatkan nilai p sebesar 0,000 (p < 0,05). Nilai spesifitas 96,6 % dan sensitivitas 100 %. Dapat disimpulkan bahwa CBM lebih cepat dan sensitif daripada LJ, namun LJ lebih spesifik daripada CBM. Kata kunci : Media kultur, Mycobacterium tuberculosis, Sputum suspek TB.
Pengaruh Kompres Hangat Rebusan Jahe Terhadap Tingkat Nyeri Subakut dan Kronis pada Lanjut Usia dengan Osteoarthtritis Lutut di Puskesmas Arjuna Kecamatan Klojen Malang Jawa Timur Masyhurrosyidi, Hadi; Kumboyono, Kumboyono; Utami, Yulian Wiji
Majalah Kesehatan FKUB Vol 1, No 1 (2014)
Publisher : Faculty of Medicine Universitas Brawijaya

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Abstract

Osteoarthritis lutut merupakan gangguan pada sistem muskuloskeletal yang ditandai dengan munculnya nyeri sendi dan kekakuan yang mengakibatkan penurunan kemampuan fisiologis atau kualitas hidup lansia. Prevalensi osteoarthritis lutut menurut WHO (2004), mencapai 151,4 juta jiwa dan 27,4 juta jiwa berada di Asia Tenggaradan di Indonesia mencapai 5 % pada usia &lt; 40 tahun, 30 % pada usia 40-60 tahun, dan 65 % pada usia &gt; 61 tahun. Untuk menurunkan angka ini diperlukan keperawatan lanjut usia dan keluarga untuk meningkatkan kualitas hidup. Penelitian ini bertujuan untuk mengetahui perbedaan tingkat nyeri subakut dan kronis sebelum dan sesudah kompres hangat rebusan jahe pada lansia dengan osteoarthritis lutut di Posyandu Lanjut Usia Puskesmas Arjuna Kecamatan Klojen Malang Jawa Timur. Penelitian ini menggunakan desain quasy experiment. Populasi penelitian adalah semua lanjut usia dengan osteoarthritis lutut yang mengikui posyandu lanjut usia Puskesmas Arjuna Kecamatan Klojen Malang Jawa Timur yang berjumlah 20 orang yang diambil secara total sampling, memakai uji statistik paired mean dependent (Uji T) dengan tingkat signifikansi 0,05. Secara keseluruhan ada hubungan yang bermakna antara tingkat skala nyeri sebelum dan setelah pemberian kompres hangat rebusan jahe dengan p-value 0.000. Pada data pre dan post treatment didapatkan penurunan skala nyeri dari berat ke sedang, dari skala sedang ke rendah dan tidak mengalami skala nyeri dari rendah ke sedang atau tinggi. Ada perbedaan signifikan tingkat nyeri sebelum dan setelah pemberian kompres hangat rebusan jahe pada lanjut usia dengan osteoarthritis lutut. Kata kunci : Jahe, Kompres hangat, Lanjut usia, Nyeri, Osteoarthritis lutut.
Pengaruh Pemberian Ekstrak Etanol Daun Melati (Jasminum sambac L. Ait) secara Topikal terhadap Peningkatan Kontraksi Luka Bakar Derajat II A pada Tikus Putih (Rattus norvegicus) Galur Wistar Wibawani, Larasati; Wahyuni, Endang Sri; Utami, Yulian Wiji
Majalah Kesehatan FKUB Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Brawijaya

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Abstract

Setiap tahun sekitar 2,5 juta kasus luka bakar terjadi di Indonesia dan kejadian luka bakar derajat II A banyak terjadi dalam kehidupan sehari-hari. Penanganan luka bakar dengan penggunaan dressing atau obat topikal masih mempunyai harga yang relatif mahal. Daun melati memiliki kandungan saponin, tanin, dan flavonoid yang membantu proses penyembuhan luka. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak etanol daun melati terhadap peningkatan kontraksi luka bakar derajat II A pada tikus putih galur Wistar. Penelitian ini menggunakan design true-experiment dengan metode post test only control group design. Ada 5 kelompok penelitian yaitu 2 kelompok kontrol menggunakan NS 0,9 %, SSD 1 % dan 3 kelompok perlakuan menggunakan ekstrak daun melati 15 %, 30 %, dan 45 %.  Variabel penelitian ini adalah peningkatan kontraksi luka bakar derajat II A yang dihitung pada hari ke-15 dari perawatan luka. Uji one way ANOVA menunjukan ada perbedaan yang signifikan pada  peningkatan kontraksi luka antara NS 0,9 %, SSD 1 %, ekstrak daun melati 15 %, 30 %, dan 45 %  dengan nilai p (0,023) &lt; α (0,05). Hasil uji post hoc menunjukan perbedaan yang signifikan antara NS 0,9 % dengan ekstrak daun melati 45 % dengan nilai p (0,036) &lt; α (0,05), tetapi tidak ada perbedaan yang signifikan antara ketiga dosis ekstrak daun melati. Kesimpulan penelitian ini adalah ekstrak daun melati 45 % mampu meningkatkan kontraksi pada luka yang lebih optimal dibandingkan NS 0,9 %, SSD 1 %, ekstrak daun melati 15 % dan 30 %. Kata kunci: Ekstrak daun melati konsentrasi 15 %, 30 %, dan 45 %, Kontraksi luka, Luka bakar derajat II A, NS 0,9 %, SSD 1 %.
Effects of Islamic Spiritual Mindfulness on Stress among Nursing Students Munif, Badrul; Poeranto, Sri; Utami, Yulian Wiji
Nurse Media Journal of Nursing Vol 9, No 1 (2019): (JUNE 2019)
Publisher : Department of Nursing, Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.587 KB) | DOI: 10.14710/nmjn.v9i1.22253

Abstract

Background: Academic stress is a major problem that often occurs in nursing students. Islamic spiritual mindfulness (ISM) is an adaptive coping strategy used to mitigate various negative psychological reactions to respond stressors experienced by the body to build self-awareness that any problems experienced today are the scenario of Allah.Purpose: This study aimed to determine the effects of Islamic spiritual mindfulness therapy to reduce stress.Methods: This study used a pre-post quasi-experimental design with a control group. Participants were bachelor students of nursing who are Muslim and experienced stress in working on the thesis (n=36) and were assigned to two groups: the experimental group receiving Islamic spiritual mindfulness and the control group. Data were collected using questionnaires of Depression Anxiety Stress Scale (DASS) and analyzed using paired t-test and unpaired t-test.  Results: The results showed that the mean stress level of students in the intervention group decreased from 20.6±2.97 to 11.4±5.81 after the intervention. Meanwhile, in the control group, the mean student stress level slightly decreased from 19.7±2.82 to 17.8±5.01. The t-test obtained a p-value of 0.001, indicating that there were significant differences in stress levels between the intervention group and the control group. The effect size obtained the value of 0.59, meaning the level of influence was in the medium category.Conclusion: This study concluded that Islamic spiritual mindfulness was effective in reducing stress among nursing students working on the thesis. It is recommended for the nursing profession, especially mental health nurses, to apply Islamic spiritual mindfulness therapy as one of the psychotherapy interventions.
Latihan Renang Intensitas Berat Lebih Meningkatkan Kekuatan Daya Rentang Utami, Yulian Wiji
Jurnal Kedokteran Brawijaya Vol 25, No 1 (2009)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (53.507 KB) | DOI: 10.21776/ub.jkb.2009.025.01.6

Abstract

ABSTRACTThe objective of this study was to prove that light intensity and heavy intensity of swim training can improvewide area of cross section, amount of fibroblas cell and thick of sharpey's fibre at achiles tendon. This studyused separate sample pretest-posttest control group design, with experimental animals the white rat (Rattusnorvegicus strain Wistar) Male, age around 3 weeks, counted 28 tails. Two treatment type that given were (1)light intensity of swim training (with giving of burden 3% Body Weight) and (2) heavy intensity of swim training(with giving of burden 9% Body Weight). Data is analysis by descriptive statistic, MANOVA and deskriminantest with trust level of 95%. Result of study was showed light intensity of swim training and heavy intensity, tobe increasing of wide area of cross section, amount of fibroblas cell and thick of sharpey's fibre compare toposttest control. MANOVA test result to respon change of treatment effect which get that treatment givesignificant difference (Trace Holtelling's, p&lt;0,05). From discriminant test result was showed variable amountof fibroblas cell and thick of sharpey's fibre showing that have significant contribution of change response oftreatment (p&lt;0,05), while variable wide area of cross section not showed significant contribution have ameaning of response change of treatment effect ( p&gt;0,05).Keywords: intensity of swim training, wide area of cross section, fibroblas cell, sharpey’s fibre.
Jus Brokoli Menurunkan Kadar Low Density Lipoprotein Darah pada Tikus Model Diabetes Melitus Setyoadi, Setyoadi; Utami, Yulian Wiji; Yuliatun, Laily
Jurnal Kedokteran Brawijaya Vol 28, No 1 (2014)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (509.439 KB) | DOI: 10.21776/ub.jkb.2014.028.01.6

Abstract

Menurunkan kadar LDL merupakan salah satu fokus utama dalam terapi Diabetes Melitus untuk menurunkan risiko kematian. Brokoli (Brassica oleracea Var. Italica) kaya akan vitamin dan mineral telah digunakan sebagai terapi diet bagi penderita Diabetes Melitus, terutama untuk menurunkan kadar LDL. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh jus brokoli terhadap penurunan kadar LDL pada tikus putih model Diabetes Melitus (DM) dengan induksi STZ. Metode yang digunakan adalah experiment laboratory dengan rancangan post test only. Sampel dibagi menjadi 5 kelompok dengan 4 ekor tiap kelompok, yaitu kelompok kontrol negatif, kelompok kontrol positif (diinduksi STZ dan tanpa jus brokoli), kelompok perlakuan 1 (diinduksi STZ dan jus brokoli 2,52 g/Kg BB), kelompok perlakuan 2 (diinduksi STZ dan jus brokoli 5,04 g/Kg BB), dan kelompok perlakuan 3 (diinduksi STZ dan jus brokoli 7,56 g/Kg BB) dengan perlakuan 14 hari. Uji one way ANOVA yang dilanjutkan uji Tuckey menunjukkan terjadi penurunan yang signifikan (p=0,000) kadar LDL pada tikus model DM, pada ketiga dosis dengan kadar LDL terendah pada dosis 7,56g/kgBB. Dapat disimpulkan pemberian jus brokoli menurunkan LDL darah pada tikus model DM.Kata Kunci: Diabetes Melitus, jus brokoli, penurunan kadar LDL
Reasons and Hindrances of the Community Leaders in Releasing Stocked Persons with Mental Problems in Southern East Sulawesi Patawari, Abdul; Wihastuti, Titin Andri; Muslihah, Nurul; Astari, Asti Melani; Utami, Yulian Wiji
Jurnal Kedokteran Brawijaya Vol 31, No 3 (2021)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2021.031.03.3

Abstract

Undertaking stock punishment is an action to immobilized individuals that suffer mental health disorders. It is mostly done by placing woods on individuals' ankles. They are designed to restrict the patients' movements and made from wooden bars. The patients are chained or locked in a special room. A community leader, as the leader of certain people, has important roles in undertaking the stocks. It is done by considering various reasons based on the constructed understanding and emerging assumptions in the middle of society. This research aims to explore the reasons and hindrances of the community leader in releasing the stocks undertaken on individuals with mental health disorders. The applied research method is qualitative research with an interpretative phenomenology. 7 participants were selected by using purposive sampling. Then, an analysis was carried out by the Interpretative Phenomenological Analysis (IPA). The findings dealing with the reasons for the community leader to undertake the stocks consisted of two themes. They dealt with the administered medication to recover individuals with mental health disorders and to protect them, their families, and society. Meanwhile, the hindrances of the community leader in discharging or releasing the punishment dealt with the difficulty to get psychiatric service. The conclusions are the stocks reasons deal with a lack of the community leader's understanding to care for the individuals with mental health disorders and the necessity of active participation of medical officers. Thus, the people could obtain maximum psychiatric service
A Correlation between Working Environment and Job Experience Toward Culture Shock among Indonesian Nurses in Japan Erwin Yektiningsih; Asti Melani Astari; Yulian Wiji Utami
Jurnal Ners Vol. 16 No. 1 (2021): APRIL 2021
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jn.v16i1.23824

Abstract

Introduction: Indonesian nurses living and working in Japan with a culture likely to be very different from their own may be additional sources of culture shock, feeling confusion and discomfort when living in a new country. They also experience difficulties in maladaptive adjustments to the new environment to overcome culture shock, then they get stressed in a working environment which can   decrease   work motivation and quality of performance.Methods: This study used a cross-sectional approach with a non-probability sampling method. The sample is 90   Indonesian nurses having been working in Japanese hospitals, both those passing the National Board Examination (NBE) and those not. Working environment (job satisfaction, colleague, rule of employment) and job experience were independent variables and culture shock was dependent variable. Work environment research instruments were from the revised questionnaire modification Scale of Socio-Cultural Adaptation (SCAS-R), the substance of work performance, job experience questionnaire and the Culture Shock Questionnaire (CSQ). Data analysis used Spearman-rho and multiple logistic regression statistical tests.Results: The average of respondents who did not experience culture shock or normal  was 44 (49%) and respondents who experienced culture shock were a poor level of 36 (40%) and moderate level of 10 (11%). Job satisfaction (ρ value = 0.001) and colleague (ρ value = 0.000) have a significant correlation with culture shock. Rule of employment (ρ value = 0.174) and job experience (ρ value = 0.209) were not significant with culture shock. Multiple logistic regression analysis was conducted to figure out the predictors that influence the change in culture shock status while a colleague (β = 2.445, p value < 0.000).Conclusion: The results of the research showed that colleagues in the work environment had a significant influence effect on cultural shock. Therefore, it is necessary to provide social support to adaptive adjustment and stress management to Indonesian nurses in Japan so that they can impact increased quality performance.
Relationship Between Sedentary Behavior and the Incidence of Constipation During the COVID-19 Pandemic Elvira Sari Dewi; Bella Cendie Asteria; Yulian Wiji Utami
Journal of Nursing Science Update (JNSU) Vol. 9 No. 2 (2021)
Publisher : Department of Nursing, Faculty of Health Sciencce, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (294.601 KB) | DOI: 10.21776/ub.jik.2021.009.02.10

Abstract

The COVID-19 pandemic has caused changes in a variety of sectors, including education. Changes in online learning methods during the COVID-19 pandemic can increase the risk of sedentary behavior in students. Sedentary behavior is one of the factors related to constipation. This study aims to determine the relationship between sedentary behavior and the incidence of constipation during the COVID-19 pandemic in students at Universitas Brawijaya. This research is correlation research with a cross-sectional approach. Sampling used total sampling with a sample of 87 students according to the inclusion and exclusion criteria. Sedentary behavior was measured using the International Physical Activity Questionnaire – Short Form (IPAQ-SF) and the incidence of constipation was measured using the Constipation Scoring System (CSS). The correlation between sedentary behavior and the incidence of constipation was statistically analyzed using the Spearman Rank test with alpha=0.05. The results show that As many as 82.8% of students at Universitas Brawijaya have sedentary behavior and 17.2% are constipated. There was a correlation between sedentary behavior and the incidence of constipation (p=0.020; r=+0,249). In conclusion, there is a relationship between sedentary behavior and the incidence of constipation during the COVID-19 pandemic in students at Universitas Brawijaya.
Co-Authors Aat Djanatunisah Adi Santoso Ahsan Ahsan Ahsan Ahsan Akhiyan Hadi Susanto Anisful Lailil Munawaroh, Anisful Lailil Asti Melani Astari Bella Cendie Asteria Dina Dewi Sartika Lestari Ismail Dwi Yuni N.H, Dwi Yuni Elvira Sari Dewi Erwin Yektiningsih Fatma, Endah Panca Lydia Gadis Mutiara PI, Gadis Mutiara Hadi Masyhurrosyidi, Hadi Hengky Rivaldi Ika Rahmawati Kumboyono Kumboyono Kuswantoro Rusca Putra Laily Yuliatun Larasati Wibawani, Larasati Lilik Supriati M. Hidayat Moh Husyn Ainul Yaqin Muhamad Nur Rahmad Muhammad Rivai Munif, Badrul Nurdiana Nurdiana Nurul Muslihah Patawari, Abdul Rahmad, Muhamad Nur Salsabila, Jihan Setyoadi Setyoadi Sri Poeranto, Sri Susanto, Akhiyan Hadi Titin Andri Wihastuti Ulfa, Kholifatu Winda Yuniarsih Wisnasari, Shila Yanli Everson Tuwohingide Yulianti, Lena