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All Journal Majalah Kedokteran Bandung Zenit Science and Technology Indonesia Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Oceana Biomedicina Journal E-Prodenta Journal of Dentistry MDJ (Makassar Dental Journal) SWARNA Cakradonya Dental Journal Indonesian Journal of Dentistry
Vinna Kurniawati Sugiaman, Vinna Kurniawati
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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PENGAJARAN MENGENAI TEKNIK MENYIKAT DAN PENGGUNAAN BENANG GIGI KEPADA PANTI ASUHAN PUTERA MARANATHA SERTA EVALUASI KEBERHASILANNYA Sugiaman, Vinna Kurniawati; Varensia, Ellyvia; Kristianti, Vivian Okta; Kristiawan, Sarah Parmashta; Christiane, Jesslyn Febe; Batuaji, Stefani Alphina; Saputra, Albertus Christian; Setiawan, Angelique Aprilla; Santoso, Chillie Aimeelita; Chriscendio, Felix
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 12 (2024): SWARNA : Jurnal Pengabdian Kepada Masyarakat, Desember 2024
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/swarna.v3i12.1470

Abstract

Kesehatan gigi dan mulut memegang peranan penting dalam menjaga kualitas hidup seseorang. Namun, pemahaman dan penerapan teknik menyikat gigi serta penggunaan benang gigi yang baik dan benar sering kali masih kurang, terutama di kalangan anak-anak. Penelitian ini bertujuan untuk memberikan edukasi mengenai teknik menyikat gigi dan penggunaan benang gigi kepada anak-anak di Panti Asuhan Putera Maranatha serta mengevaluasi keberhasilannya. Metode yang digunakan meliputi penyuluhan dengan demonstrasi langsung, pembagian materi edukasi visual, dan evaluasi. Evaluasi dilakukan melalui kuesioner pre-test dan post-test. Hasil penelitian menunjukkan peningkatan dalam pemahaman dan keterampilan anak-anak dalam menjaga kesehatan gigi dan mulut. Temuan ini menegaskan akan pentingnya program edukasi kesehatan gigi untuk meningkatkan kesadaran dan kebiasaan perawatan gigi sejak dini.
ANTIBACTERIAL ACTIVITY TEST OF STRAWBERRY (FRAGARIA × ANANASSA) FRUIT EXTRACT AGAINST THE GROWTH OF STREPTOCOCCUS SANGUINIS Pascharia, Theresia Imelda; Sugiaman, Vinna Kurniawati; Dwiarie, Theodora Adhisty
Indonesian Journal of Dentistry Vol 5, No 2 (2025): August 2025
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/ijd.v5i2.17544

Abstract

Background: Strawberry (Fragaria × ananassa) is a natural substance known to reduce dental plaque formation due to its content of bioactive compounds, including saponins, tannins, alkaloids, steroids, and triterpenoids. This study aimed to evaluate the antibacterial activity of strawberry fruit extract, prepared using 70% ethanol as a solvent through maceration to produce a concentrated liquid extract, against Streptococcus sanguinis—a bacterium associated with plaque formation.Method: The study employed microdilution and agar dilution methods. Antibacterial activity was assessed through the determination of the Minimum Inhibitory Concentration (MIC), indicated by a marked decrease in optical density, and the Minimum Bactericidal Concentration (MBC), determined by the absence of bacterial colony growth.Outcome: Results showed that the MIC of the strawberry extract against S. sanguinis was 6.25%, while the MBC was 50%.Conclusion: These findings indicate that strawberry extract (Fragaria × ananassa) exhibits both inhibitory and bactericidal activity against the growth of Streptococcus sanguinis.
Potential of Secretome Hydrogel for Wound Healing in LPS- and Scratch-Induced BJ Cells as an Inflammation Model Widowati, Wahyu; Rahmat, Deni; Faried, Ahmad; Nainggolan, Ita Margaretha; Priyandoko, Didik; Wargasetia, Teresa Liliana; Sugiaman, Vinna Kurniawati; Triharsiwi, Dwi Nur; Qlintang, Sandy; Murti, Harry; Azis, Rizal; Jeffrey, Jeffrey
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1242-1254

Abstract

Wound healing often requires specialized interventions to accelerate recovery due to prolonged inflammation and limited regenerative factors. Umbilical Cord Mesenchymal Stem Cells secretome (UCMSCs) comprises various cytokines and growth factors that can promote wound healing. This study aims to analyze the potential of a secretome-based hydrogel as a wound-healing agent using BJ fibroblast cells induced by lipopolysaccharide (LPS) and scratch injury as an inflammation model. The secretome hydrogel was formulated using Carbopol, Hydroxypropyl Methylcellulose (HPMC), Hydroxyethyl Cellulose (HEC), and secretome. Cytotoxicity was conducted using the WST-8 assay, while cell migration was evaluated through a scratch assay. Tumor Necrosis Factor-???? (TNF-????), Nuclear Factor kappa-B (NF-????B), and Interleukin-8 (IL-8) gene expression were analyzed via qRT-PCR. Additionally, malondialdehyde (MDA) levels were measured for oxidative stress assessment, whereas Connective Tissue Growth Factor (CTGF) and Transforming Growth Factor-????1 (TGF-????1) levels were quantified using ELISA and colorimetric assays. The secretome hydrogel exhibited no cytotoxic effects on BJ fibroblast cells and significantly enhanced cell migration. Moreover, it reduced the TNF-????, IL-8, and NF-????B expression, indicating anti-inflammatory activity. The hydrogel also decreased MDA levels while increasing TGF-β1 and CTGF expression, suggesting antioxidant properties and enhanced tissue regeneration in the inflammatory model. The secretome-based hydrogel presents a promising therapeutic approach for promoting chronic wound healing by modulating inflammation, reducing oxidative stress, enhancing tissue regeneration, and stimulating fibroblast migration.
Efektivitas Sediaan Pasta Gigi Ekstrak Teh Hijau (Camellia sinensis L.) dan Peppermint (Mentha piperita L.) terhadap Indeks Plak dan pH Saliva Manurung, Mian Maranata Br; Sugiaman, Vinna Kurniawati; Widowati, Wahyu
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 36, No 1 (2024): April 2024
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v36i1.53001

Abstract

ABSTRAK Pendahuluan: Plak merupakan lapisan lunak yang terdiri dari kumpulan bakteri yang tumbuh pada permukaan gigi. Pertumbuhan plak dapat berhubungan dengan saliva, sehingga untuk menjaga pH saliva rongga mulut tetap normal perlu dilakukan kontrol plak. Produk herbal seperti pasta gigi yang mengandung teh hijau dan peppermint dapat berpengaruh dalam pencegahan pembentukan plak dan pH saliva. Penelitian ini bertujuan untuk menganalisis efektivitas sediaan pasta gigi ekstrak teh hijau (Camellia sinensis L.) dan peppermint (Mentha piperita L.) terhadap indeks plak dan pH saliva. Metode: Jenis penelitian berupa eksperimental dengan desain pretest dan post test. Subjek sebanyak 32 orang dipilih berdasarkan kriteria inklusi dan kriteria eksklusi yang kemudian dibagi menjadi dua kelompok (n=16) secara random. Kelompok pertama menyikat gigi menggunakan pasta gigi ekstrak teh hijau, peppermint dan kelompok kedua menyikat gigi menggunakan pasta gigi pembanding. pH saliva kedua kelompok diukur menggunakan pH meter dan skor plak gigi menggunakan metode O’Leary. Metode analisis data yang digunakan adalah uji Wilcoxon. Hasil: Kelompok pertama dan kedua menunjukkan tidak terdapat perubahan signifikan pada pH saliva (p=0,068 dan p=0,729) namun terdapat perubahan signifikan pada indeks plak (p=0,000 dan p=0,033). Simpulan: Menyikat gigi menggunakan pasta gigi yang mengandung ekstrak teh hijau (Camellia Sinensis L.) dan peppermint (Mentha piperita L.) memiliki efektivitas dalam menurunkan indeks plak serta menjaga pH saliva tetap dalam keadaan normal. Kata kunci indeks plak, pasta gigi, peppermint, pH saliva, teh hijau  Effectiveness of green tea (Camellia sinensis L.) and peppermint (Mentha piperita L.) toothpaste extracts on plaque index and saliva pH: a laboratory experiment ABSTRACT Introduction: Plaque is a soft layer consisting of a collection of bacteria that grows on the surface of the teeth. Plaque growth can be related to saliva, so to maintain the pH of oral saliva remaining normal, it is necessary to control plaque. Herbal products such as toothpaste containing green tea and peppermint can prevent plaque and salivary pH. This research was conducted to determine the effectiveness of green tea (Camellia sinensis L.) and peppermint (Mentha piperita L.) toothpaste preparations on plaque index and salivary pH. Methods: The research design is experimental with a pretest-posttest design. A total of 32 subjects were recovered based on inclusion and exclusion criteria and then divided into two groups (n=16) randomly. The first group brushed their teeth using green tea extract toothpaste, peppermint and the second group brushed their teeth using CT toothpaste. The saliva pH of both groups was measured using a pH meter and dental plaque scores using the O'Leary method. The data analysis method used is the Wilcoxon test.  Results: The results of the first and second groups of research showed that there was no significant change in saliva pH (p=0.068 and p=0.729) but there was a significant change in the plaque index (p=0.000 and p=0.033). Conclusion: Brushing teeth using toothpaste containing green tea (Camellia Sinensis L.) and peppermint (Mentha piperita L.) extracts is effective in reducing the plaque index and maintaining saliva pH within normal conditions. Keywords green tea, peppermint, plaque index, saliva pH, toothpaste
Co-Authors Agung Novianto, Agung Ahmad Faried Azis, Rizal Batuaji, Stefani Alphina Calvin Kurnia Chriscendio, Felix Christiane, Jesslyn Febe Didik Priyandoko Dwiarie, Theodora Adhisty Felicia, Anindhita Cindy Ferdiansyah, Rival Harry Murti Ignatius Setiawan, Ignatius Jeffrey ., Jeffrey Kristianti, Vivian Okta Kristiawan, Sarah Parmashta Kurniawan, Viola Febi Laksmi, Primarizka Iswara Mandalas, Henry Yonatan Manurung, Mian Maranata Br Mellinia, Patricia Octaviane Nainggolan, Ita Margaretha Natallia Pranata Pascharia, Theresia Imelda Posumah, Gabriela Lestari Natalya Pradipta, Regina Pratiwi, Gracia Yodianvi Qlintang, Sandy RAHMAT, DENI Rahmawati, Dicha Yuliadewi Sanjaya, Oei Tirza Cintya Santoso, Chillie Aimeelita Saputra, Albertus Christian Setiawan, Angelique Aprilla Sinaga, Nadya Atalia Teresa Liliana Wargasetia Triharsiwi, Dwi Nur Varensia, Ellyvia WAHYU WIDOWATI Zalzamitha, Tifanny