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All Journal Jurnal Ilmiah Kedokteran Wijaya Kusuma Health Notions Jurnal Ilmu Kedokteran dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal ABDINUS : Jurnal Pengabdian Nusantara Sehat Rakyat: Jurnal Kesehatan Masyarakat Eduvest - Journal of Universal Studies Prominentia Medical Journal Jambura Medical and Health Science Journal Jurnal Medicare Prosiding Seminar Nasional COSMIC Kedokteran Folia Medica Indonesiana
Anna Lewi Santoso
Universitas Wijaya Kusuma Surabaya
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

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Optimalisasi Kesehatan Mental dan Perilaku Remaja Menuju Generasi Unggul Melalui Penyuluhan Siswa-Siswi SMPN 8 Surabaya - Jawa Timur Sanjaya, Ayling; Santoso, Anna Lewi; Winoto, Haryson Tondy; Sunarpo, James Hadiputra; Putri, Made Ayu Prasasti Dwitama
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 8 No 1 (2024): Volume 8 Nomor 1 Tahun 2024
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v8i1.21624

Abstract

Permasalahan mental dan perilaku pada remaja masih menjadi masalah yang serius di dunia dan di Indonesia. Gangguan mental dan perilaku pada remaja sering tidak terdeteksi dan terabaikan dalam penanganannya sehingga berisiko dalam pembentukan karakter menuju dewasa serta mempengaruhi kualitas dan masa depannya sehingga perlu penyuluhan dan sosialisasi. Tujuan Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan informasi mengenai pentingnya optimalisasi kesehatan mental dan perilaku remaja bagi masa depan menuju generasi unggul. Metode Pengabdian masyarakat dilakukan pada remaja berupa penyuluhan kepada remaja mengenai pentingnya optimalisasi kesehatan mental dan perilaku demi menjadi generasi unggul dan memiliki masa depan yang baik Pelaksanaan kegiatan ini meliputi ceramah dalam bentuk presentasi, diskusi, dan konseling. Pre-test dan post-test dilakukan sebelum dan sesudah kegiatan ini. Sebanyak 600 peserta mengikuti kegiatan ini, diantaranya, Kepala Sekolah, Guru, dan Siswa SMPN 8 Surabaya. Hasil Ditemukan sebanyak 309 (68,7%) siswa remaja merasa memiliki masalah dengan keluarga, sekolah ataupun teman. Terdapat peningkatan kemampuan peserta dalam kesadaran pentingnya optimalisasi kesehatan mental dan perilaku remaja setelah dilakukan penyuluhan di mana terjadi peningkatan peserta dengan nilai nilai baik di post-test meningkat dibandingkan pre-test. Ringkasan Penyuluhan mengenai optimalisasi kesehatan mental dan perilaku remaja menuju generasi unggul sangat efektif.
Ethanol extract of mangosteen peel reduces histological count of alveolar macrophage and pulmonary alveolar space size in male white rats (rattus norvegicus) exposed to cigarette smoke Santoso, Anna Lewi
Folia Medica Indonesiana Vol. 51, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

This study aims to analyze histological alveolar macrophage cell number and width of pulmonary alveolar space white male rats given ethanol extract of mangosteen peel and then exposed to cigarette smoke. Smoking can reduce antioxidant and increases free radicals, so it is recommended increasing the antioxidants found in many mangosteen rind. This research was an experimental laboratory using the randomized post test-only control group design. White rats male were chosen randomly into 5 groups (K1, K2, P1, P2, P3). K1 (control-), only the Na-CMC 0.5%, K2 (control+) given Na-CMC 0.5% solution and smoke, P1, P2, P3 given the ethanol extract of mangosteen rind (50, 100, and 200mg/kg wt) and smoke. The data were tested normality and homogenity. Then they were analyzed with one-way Anova, LSD. Data that are not normally tested with Robust tests – (Brown-Forsythe) and Tamhane's. Correlation test with Pearson and Spearman. Robust test results, the number of alveolar macrophages, value p=0.000 (p
PENYULUHAN KESEHATAN PADA KEGIATAN “PONDOK OSTEOARTRITIS” SEBAGAI UPAYA PENCEGAHAN DAN PENURUNAN PROGRESIVITAS PENYAKIT MELALUI PENGENDALIAN DIET KARBOHIDRAT Khamidah, Nur; Santoso, Anna Lewi; Njoto, Ibrahim; Arief, Handy
Prosiding Seminar Nasional COSMIC Kedokteran Vol 4 (2026): Edisi 2026
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat Universitas Wijaya Kusuma Surabaya

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Abstract

Latar Belakang: Ostheoartritis merupakan penyakjit degenerative yang banyak diderita pada kelompok lansia. Penyakit ini memiliki gejala sakit nyeri sendi, terutama pada lansia. Berdasarkan kegiatan pengabdian masyarakat yang telah dilakukan di posyandu lokasi sebelumnya diketahui bahwa lansia yang melakukan pemeriksaan ternyata terdiagnosa ostheoartritis, meskipun untuk kepastian diagnose masih dibutuhkan pemeriksaan lebih lanjut. Hal ini menunjukan bahwa penyakit ini faktanya banyak terjadi di masyarakat, tetapi tidak disadari sehingga diketahui penyakit pada keadaan tahap lanjut. Dengan demikian dibutuhkan kegiatan berbasis masyarakat melalui “Pondok ostheoartritis” dengan bekerjasama dengan kader posyandu lansia untuk memberikan informasi dan edukasi pada masyarakat. Metode: kegiatan pengabdian masyarakat ini melakukan pemeriksaan untuk diagnosis pasien ostheoartritis, selain itu pada saat pemeriksaan dilakukan penyuluhan dengan menggunakan media overhead projector (OHP) dan leaflet tentang pengendalian diet karbohidrat untuk mencegah keparahan akibat ostheoartritis. Pada saat pelaksanaan kegiatan juga akan diputarkan video edukasi tentang ostheoartritis. Indikator keberhasilan program adalah dengan mengukur kuesioner pengetahuan yang diberikan pada peserta. Hasil luaran berupa jurnal serta video pelaksanaan kegiatan. Selain itu kegiatan pengabdian masyarakat ini juga akan diintegrasikan dengan kebiatan belajar mahasiswa. Kesimpulan: kegiatan Pondok OA dapat memberikan manfaat untuk masyarakat setempat. Sehingga mahasiswa Fakultas Kedokteran tingkat sarjana juga memiliki pengalaman pemeriksaan pasien yang di dampingi oleh dokter baik sebagai dosen maupun praktisi yang ada di puskesmas.
Pengaruh Ekstrak Kulit Manggis Terhadap Histologi Jumlah Sel Nekrosis Pulau Langerhans Tikus Putih Jantan Hiperglikemik Lewi Santoso, Anna; Lewi Santoso, Jemima
Bahasa Indonesia Vol 6 No 2 (2025): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v6i2.6012

Abstract

The aim of this study was to analyze the histological profile of necrotic cell counts in the islets of Langerhans in hyperglycemic male white rats given mangosteen peel extract. Hyperglycemic conditions can form reactive oxygen species (ROS)/free radicals. Excessive ROS can cause oxidative stress and exacerbate cell necrosis in the islets of Langerhans. Mangosteen peel contains the antioxidant compound, Xanthone, an organic compound derived from diphenyl-γ-pyrone that can neutralize ROS and inhibit islet cell necrosis. This study employed a randomized post-test-only control group design. Four groups of male white rats: the untreated group (normal), the alloxan-induced group, the 250, and 500 mg/kgBW dose groups. The data results were tested using Kruskal-Wallis. The results of the study indicated that mangosteen peel extract had an effect on the histological profile of necrotic cell counts in the islets of Langerhans in male white rats experiencing hyperglycemia; with the number of necrotic cells decreased, the mangosteen peel extract dose of 250 mg was 19.2, and the dose of 500 mg was 18.4. Mangosteen peel extract had an effect on necrotic cells in the islets of Langerhans
The Relationship Between Screen Time Duration And Speech Delay In Children Aged 0-6 Years In Malang City Safira, Safira; Sanjaya, Ayling; Santoso, Anna Lewi
Health Notions Vol 10, No 3 (2026): March
Publisher : Humanistic Network for Science and Technology (HNST)

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Abstract

Excessive screen time in early childhood can affect various aspects of development, including speech abilities. This study aims to determine the relationship between screen time duration and the occurrence of speech delay in children aged 0–6 years in Malang City. A case–control design was used with a total of 60 children, consisting of 30 children with speech delay and 30 children with normal speech development. Data were collected using a questionnaire measuring daily screen time duration and the Developmental Pre-Screening Questionnaire (KPSP) to assess developmental status. Statistical analysis using the Chi-Square test showed a significant relationship between screen time duration and speech delay (p = 0.000). The findings indicate that children exposed to screen time for more than one hour per day have a higher risk of experiencing speech delay compared to those with limited exposure. These results highlight the important role of parents in supervising and limiting the use of digital media. By reducing screen time and increasing direct interaction, children’s speech and language development can be better supported. This study concludes that managing screen time is a crucial step in preventing speech delay in early childhood
Association Between Serum IL-8 Concentrations and Severity of Knee Osteoarthritis: An Exploratory Cross-Sectional Study Iskak, Iskak; Dewanta, Tunggul Bagus; Santoso, Anna Lewi; Aryanti, Novina; Syahzaqi, Idrus; Njoto, Ibrahim
Jambura Medical and Health Science Journal Vol 5, No 1 (2026): Jambura Medical and Health Science Journal
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jmhsj.v5i1.37399

Abstract

Introduction: Osteoarthritis (OA) is a chronic degenerative disorder of the joints that progresses over time, with inflammation playing a key role in its underlying mechanisms. Interleukin-8 (IL-8), a pro-inflammatory cytokine that participates in immune responses and neutrophil migration, has been associated with the process of cartilage breakdown in OA. This study was conducted to analyze the association between serum IL-8 concentrations and the radiographic severity of knee OA as exploratory evidence to enhance understanding of OA pathophysiology.Method: This exploratory observational research applied a cross-sectional approach in patients diagnosed with knee OA. Seven participants were enrolled through total sampling at the Larasati Pondok Osteoarthritis Elderly Health Center, Faculty of Medicine, Wijaya Kusuma University, Surabaya. Radiographic severity of OA was determined using the Kellgren–Lawrence grading system. Venous blood specimens were obtained to determine serum IL-8 concentrations as an indicator of systemic inflammation.Results: Statistical analysis demonstrated a significant inverse correlation between serum IL-8 concentrations and OA severity (r = −0.866, P = 0.012). These results indicate that IL-8 concentrations in serum are relatively elevated in the early phase of OA and tend to decline as the disease progresses.Conclusion: The findings of this exploratory study indicate that serum IL-8 may represent systemic inflammatory activity during the early stages of knee OA and holds potential as a biomarker candidate for future investigation. Further longitudinal studies involving larger sample sizes are necessary to validate its clinical relevance for OA detection and disease monitoring. Keywords: Cartilage, inflammation, interleukin-8, joint diseases, osteoarthritis, risk factors 
The Effects of Krill Oil Content on Asthma Jemima Lewi Santoso; Anna Lewi Santoso
Eduvest - Journal of Universal Studies Vol. 4 No. 7 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i7.1534

Abstract

Asthma is a lung disease that is increasing in the number of patients and whose severity is difficult to control. Various single antioxidants have been studied to reduce the severity and period of asthma exacerbations but the appropriate intervention compound has yet to be found. Krill oil contains various kinds of antioxidant compounds at high levels. Objective: To explain the effect of the antioxidant compounds in krill oil on asthma. Research Methods: Several journals and articles examined the effects of each antioxidant compound in krill oil on asthma. Results: several studies have shown that the effects of antioxidant compounds in krill oil can reduce inflammation and exacerbations of asthma. Conclusion: Biomolecular research is needed to determine the levels of antioxidant compounds in krill oil considering that the composition of krill oil can easily change due to various factors.
The Relationship Between Maternal Employment Status and Speech Delay in Early Childhood: A Case-Control Study from a Private Pediatric Clinic in Malang, Indonesia Nathania Lisna Ardelia; Ayling Sanjaya; Anna Lewi Santoso
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 4 No. 4 (2025): November 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v4i4.6067

Abstract

Speech delay is a common developmental concern in early childhood, affecting cognitive, social, and emotional domains. Maternal employment has been hypothesized to influence speech development, potentially due to reduced parent–child interaction. However, current evidence remains inconclusive, particularly in low- and middle-income countries. This study aimed to evaluate the association between maternal employment and speech delay in children aged 0–6 years in Malang, Indonesia. A case–control study was conducted from January to March 2025 at a private pediatric clinic in Malang City, Indonesia. A total of 60 children were recruited through consecutive sampling and categorized into two groups: 30 children with speech delay (cases) and 30 with typical speech development (controls). Maternal employment status and relevant sociodemographic data were collected using structured questionnaires. Speech development was assessed using the validated Kuesioner Pra Skrining Perkembangan (KPSP). Statistical analysis was performed using the Chi-square test, with significance set at p < 0.05. Of the total participants, 27 mothers (45.0%) were employed. Among children of employed mothers, 48.1% had speech delay, compared to 51.5% among children of non-employed mothers. The association between maternal employment and speech delay was not statistically significant (χ² = 0.07; p = 0.795). No significant association was found between maternal employment and speech delay. These findings suggest that emphasis should shift from employment status to enhancing the quality of parent–child interaction and promoting early developmental support in diverse family contexts.
Co-Authors Anggono, Susan Anggono, Susan Jocelyn Arief, Handy Aryanti, Novina Ayling Sanjaya Dewanta, Tunggul Bagus Goein, Amadeus Michel Hamdan, Maulana Muhammad Hisyam Ibrahim Njoto, Ibrahim Idrus Syahzaqi Iskak, Iskak Jemima Lewi Santoso Lewi Santoso, Jemima Lewi, Jemima Loo Hariyanto Raharjo, Loo Hariyanto Nanda, Karisa Betha Nathania Lisna Ardelia Nur Khamidah Prameswari, Yaasmiin Zivana Regita Prasetyo, Mohammad Yudhi Putri, Diah Arrizah Putri, Made Ayu Prasasti Dwitama Safira, Safira Sudibjo, Sudibjo Sunarpo, James Hadiputra Tjokro, Vanessa Susanto Viskasari P. Kalanjati Wahyuni Dyah Parmasari, Wahyuni Dyah Winoto, Haryson Tondy