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All Journal Jurnal Ilmiah Kedokteran Wijaya Kusuma Health Notions Jurnal Ilmu Kedokteran dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal ABDINUS : Jurnal Pengabdian Nusantara Penamas: Journal of Community Service Sehat Rakyat: Jurnal Kesehatan Masyarakat Eduvest - Journal of Universal Studies Prominentia Medical Journal Jambura Medical and Health Science Journal Jurnal Medicare Prosiding Seminar Nasional COSMIC Kedokteran Folia Medica Indonesiana
Anna Lewi Santoso
Departemen Histologi, Fakultas Kedokteran Universitas Wijaya Kusuma Surabaya
Aerospace Engineering Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Hubungan Pola Asuh Orang Tua Dengan Tumbuh Kembang Anak Balita Di Mojokerto Prameswari, Yaasmiin Zivana Regita; Santoso, Anna Lewi; Sanjaya, Ayling; Parmasari, Wahyuni Dyah
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 7 (2025): Volume 12 Nomor 7
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i7.19520

Abstract

Pertumbuhan dan perkembangan anak balita merupakan proses penting yang dipengaruhi oleh berbagai factor salah satunya adalah pola asuh orang tua. Pola asuh yang diterapkan sejak dini diyakini berkontribusi terhadap optimalisasi tumbuh kembang anak. Penelitian ini bertujuan untuk menganalisis hubungan antara pola asuh orang tua dengan tumbuh kembang anak balita di wilayah kerja Puskesmas Jetis Mojokerto. Penelitian ini menggunakan desain studi cross-sectional dengan pendekatan observasional analitik. Sebanyak 45 anak usia 1–5 tahun dipilih secara acak menggunakan metode simple random sampling. Data dikumpulkan melalui kuesioner pola asuh (PSQ), pengukuran antropometri, dan Kuesioner Pra-Skrining Perkembangan (KPSP) yang kemudian dianalisis menggunakan uji chi-square dengan tingkat signifikansi α = 0,05. Hasil penelitian menunjukkan bahwa mayoritas responden (97,8%) menerapkan pola asuh authoritative. Sebagian besar anak memiliki pertumbuhan sesuai usia (88,9%) dan perkembangan sesuai usia (93,3%). Hasil uji statistik menunjukkan tidak terdapat hubungan yang signifikan antara pola asuh orang tua dengan pertumbuhan (p = 1) maupun perkembangan anak balita (p = 0,067). Kesimpulannya, tidak ditemukan hubungan yang signifikan antara pola asuh orang tua dengan tumbuh kembang anak balita. Penelitian lebih lanjut disarankan mempertimbangkan faktor lain seperti nutrisi, genetik, status sosial ekonomi, dan stimulasi lingkungan.
REVIEW PERAN VAKSIN DEMAM TIFOID UNTUK WISATAWAN DI DAERAH TROPIS Lewi Santoso, Anna; Sanjaya, Ayling; Santoso , Jemima Lewi; Njoto, Ibrahim
Jurnal Medicare Vol. 4 No. 3: JULY 2025
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v4i3.226

Abstract

Typhoid fever is a systemic infectious disease caused by Salmonella enterica subspecies enterica serovar Typhi (S. Typhi). Transmission commonly occurs through food or drinks contaminated with the feces or urine of infected individuals. Travelers to endemic areas, particularly tropical regions, are at high risk of infection. Symptoms include high fever, nausea, and abdominal pain. Improvements in sanitation and hygiene have contributed to a decline in typhoid incidence; however, the effectiveness of antibiotic treatment is decreasing due to rising resistance. Vaccination has become a highly recommended preventive measure for both local populations and travelers. This study is a literature review of English-language articles published between 2014 and 2024, sourced from PubMed (106 articles), Google Scholar (915), and ProQuest (14), using the keywords “typhoid fever” and “vaccine.” A total of 49 relevant articles were analyzed. The results show that the World Health Organization (WHO) recommends typhoid vaccination in endemic areas. In conclusion, vaccination is effective in reducing morbidity and mortality rates and in preventing antibiotic resistance. Well-planned preventive strategies are essential for protecting public health.
Neonatal Jaundice History as a Risk Factor for Speech Delay in Children Aged 0–6 Years Sanjaya, Ayling; Prasetyo, Mohammad Yudhi; Santoso, Anna Lewi
Health Notions Vol 9, No 8 (2025): August
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn90802

Abstract

Untreated neonatal jaundice can result in neurological complications, including speech delay. This study aimed to analyze the association between a history of neonatal jaundice and speech delay in children aged 0–6 years at a Private Clinic in Malang. This research applied a case-control design with a total sample of 60 children, including 30 children with speech delay and 30 children with normal speech development. Jaundice history data were collected through parent questionnaires, while speech development was assessed using the Developmental Pre-Screening Questionnaire. Data analysis used the Chi-Square test with a significance level of 0.05. The results showed no statistically significant relationship between neonatal jaundice and speech delay (p = 0.103). However, the Odds Ratio of 2.875 indicated that children with a history of neonatal jaundice were at a higher risk of experiencing speech delay. In conclusion, although no statistically significant association was found, a history of neonatal jaundice may serve as a risk factor for speech delay in children aged 0–6 years. Therefore, early developmental monitoring is strongly recommended for children with such a history. Keywords: bilirubin; early childhood; neonatal jaundice; speech delay
Hubungan Antara Lama Screen time Dengan Risiko Gangguan Pemusatan Perhatian Dan Hiperaktivitas Pada Anak Usia 3-6 Tahun Di Mojokerto Hamdan, Maulana Muhammad Hisyam; Santoso, Anna Lewi; Sanjaya, Ayling; Parmasari, Wahyuni Dyah
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 1 (2025): Volume 12 Nomor 1
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i1.16237

Abstract

Perkembangan teknologi telah menyebabkan peningkatan waktu yang dihabiskan anak-anak di depan gadget yang mungkin berpengaruh terhadap kesehatan mental mereka, termasuk potensi untuk mengembangkan Gangguan Pemusatan Perhatian dan Hiperaktivitas (GPPH). Penelitian ini melibatkan 45 anak usia 3-6 tahun yang mendapatkan pelayanan di Puskesmas Jetis Mojokerto. Data dikumpulkan melalui survei yang mencatat durasi penggunaan gadget (screen time) harian dan skor GPPH, dengan menggunakan skor cut-off  ≥ 13 sebagai indikator GPPH yang lebih tinggi. Analisis data dilakukan dengan statistik deskriptif dan uji Chi-square untuk mengevaluasi hubungan antara lama screen time dan GPPH. Dari 45 anak, 40% menghabiskan lebih dari satu jam screen time setiap hari. Anak-anak yang menghabiskan lebih dari satu jam di depan layar memiliki skor GPPH yang lebih tinggi (>13) dengan persentase 72.2%, sementara yang kurang dari satu jam hanya 18.5%. Uji Chi-square menghasilkan p value sebesar 0.001, menunjukkan adanya hubungan yang sangat signifikan antara lama screen time dan skor GPPH. Berdasarkan Hasil penelitian ini menunjukkan bahwa ada hubungan yang signifikan antara lama screen time dan kejadian GPPH pada anak usia 3-6 tahun.
Optimalisasi Kesehatan Mental dan Perilaku Remaja Menuju Generasi Unggul Melalui Penyuluhan Siswa-Siswi SMPN 8 Surabaya - Jawa Timur Sanjaya, Ayling; Santoso, Anna Lewi; Winoto, Haryson Tondy; Sunarpo, James Hadiputra; Putri, Made Ayu Prasasti Dwitama
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 8 No 1 (2024): Volume 8 Nomor 1 Tahun 2024
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v8i1.21624

Abstract

Permasalahan mental dan perilaku pada remaja masih menjadi masalah yang serius di dunia dan di Indonesia. Gangguan mental dan perilaku pada remaja sering tidak terdeteksi dan terabaikan dalam penanganannya sehingga berisiko dalam pembentukan karakter menuju dewasa serta mempengaruhi kualitas dan masa depannya sehingga perlu penyuluhan dan sosialisasi. Tujuan Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan informasi mengenai pentingnya optimalisasi kesehatan mental dan perilaku remaja bagi masa depan menuju generasi unggul. Metode Pengabdian masyarakat dilakukan pada remaja berupa penyuluhan kepada remaja mengenai pentingnya optimalisasi kesehatan mental dan perilaku demi menjadi generasi unggul dan memiliki masa depan yang baik Pelaksanaan kegiatan ini meliputi ceramah dalam bentuk presentasi, diskusi, dan konseling. Pre-test dan post-test dilakukan sebelum dan sesudah kegiatan ini. Sebanyak 600 peserta mengikuti kegiatan ini, diantaranya, Kepala Sekolah, Guru, dan Siswa SMPN 8 Surabaya. Hasil Ditemukan sebanyak 309 (68,7%) siswa remaja merasa memiliki masalah dengan keluarga, sekolah ataupun teman. Terdapat peningkatan kemampuan peserta dalam kesadaran pentingnya optimalisasi kesehatan mental dan perilaku remaja setelah dilakukan penyuluhan di mana terjadi peningkatan peserta dengan nilai nilai baik di post-test meningkat dibandingkan pre-test. Ringkasan Penyuluhan mengenai optimalisasi kesehatan mental dan perilaku remaja menuju generasi unggul sangat efektif.
Ethanol extract of mangosteen peel reduces histological count of alveolar macrophage and pulmonary alveolar space size in male white rats (rattus norvegicus) exposed to cigarette smoke Santoso, Anna Lewi
Folia Medica Indonesiana Vol. 51, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aims to analyze histological alveolar macrophage cell number and width of pulmonary alveolar space white male rats given ethanol extract of mangosteen peel and then exposed to cigarette smoke. Smoking can reduce antioxidant and increases free radicals, so it is recommended increasing the antioxidants found in many mangosteen rind. This research was an experimental laboratory using the randomized post test-only control group design. White rats male were chosen randomly into 5 groups (K1, K2, P1, P2, P3). K1 (control-), only the Na-CMC 0.5%, K2 (control+) given Na-CMC 0.5% solution and smoke, P1, P2, P3 given the ethanol extract of mangosteen rind (50, 100, and 200mg/kg wt) and smoke. The data were tested normality and homogenity. Then they were analyzed with one-way Anova, LSD. Data that are not normally tested with Robust tests – (Brown-Forsythe) and Tamhane's. Correlation test with Pearson and Spearman. Robust test results, the number of alveolar macrophages, value p=0.000 (p
PENYULUHAN KESEHATAN PADA KEGIATAN “PONDOK OSTEOARTRITIS” SEBAGAI UPAYA PENCEGAHAN DAN PENURUNAN PROGRESIVITAS PENYAKIT MELALUI PENGENDALIAN DIET KARBOHIDRAT Khamidah, Nur; Santoso, Anna Lewi; Njoto, Ibrahim; Arief, Handy
Prosiding Seminar Nasional COSMIC Kedokteran Vol 4 (2026): Edisi 2026
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat Universitas Wijaya Kusuma Surabaya

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Abstract

Latar Belakang: Ostheoartritis merupakan penyakjit degenerative yang banyak diderita pada kelompok lansia. Penyakit ini memiliki gejala sakit nyeri sendi, terutama pada lansia. Berdasarkan kegiatan pengabdian masyarakat yang telah dilakukan di posyandu lokasi sebelumnya diketahui bahwa lansia yang melakukan pemeriksaan ternyata terdiagnosa ostheoartritis, meskipun untuk kepastian diagnose masih dibutuhkan pemeriksaan lebih lanjut. Hal ini menunjukan bahwa penyakit ini faktanya banyak terjadi di masyarakat, tetapi tidak disadari sehingga diketahui penyakit pada keadaan tahap lanjut. Dengan demikian dibutuhkan kegiatan berbasis masyarakat melalui “Pondok ostheoartritis” dengan bekerjasama dengan kader posyandu lansia untuk memberikan informasi dan edukasi pada masyarakat. Metode: kegiatan pengabdian masyarakat ini melakukan pemeriksaan untuk diagnosis pasien ostheoartritis, selain itu pada saat pemeriksaan dilakukan penyuluhan dengan menggunakan media overhead projector (OHP) dan leaflet tentang pengendalian diet karbohidrat untuk mencegah keparahan akibat ostheoartritis. Pada saat pelaksanaan kegiatan juga akan diputarkan video edukasi tentang ostheoartritis. Indikator keberhasilan program adalah dengan mengukur kuesioner pengetahuan yang diberikan pada peserta. Hasil luaran berupa jurnal serta video pelaksanaan kegiatan. Selain itu kegiatan pengabdian masyarakat ini juga akan diintegrasikan dengan kebiatan belajar mahasiswa. Kesimpulan: kegiatan Pondok OA dapat memberikan manfaat untuk masyarakat setempat. Sehingga mahasiswa Fakultas Kedokteran tingkat sarjana juga memiliki pengalaman pemeriksaan pasien yang di dampingi oleh dokter baik sebagai dosen maupun praktisi yang ada di puskesmas.
Pengaruh Ekstrak Kulit Manggis Terhadap Histologi Jumlah Sel Nekrosis Pulau Langerhans Tikus Putih Jantan Hiperglikemik Lewi Santoso, Anna; Lewi Santoso, Jemima
Bahasa Indonesia Vol 6 No 2 (2025): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v6i2.6012

Abstract

The aim of this study was to analyze the histological profile of necrotic cell counts in the islets of Langerhans in hyperglycemic male white rats given mangosteen peel extract. Hyperglycemic conditions can form reactive oxygen species (ROS)/free radicals. Excessive ROS can cause oxidative stress and exacerbate cell necrosis in the islets of Langerhans. Mangosteen peel contains the antioxidant compound, Xanthone, an organic compound derived from diphenyl-γ-pyrone that can neutralize ROS and inhibit islet cell necrosis. This study employed a randomized post-test-only control group design. Four groups of male white rats: the untreated group (normal), the alloxan-induced group, the 250, and 500 mg/kgBW dose groups. The data results were tested using Kruskal-Wallis. The results of the study indicated that mangosteen peel extract had an effect on the histological profile of necrotic cell counts in the islets of Langerhans in male white rats experiencing hyperglycemia; with the number of necrotic cells decreased, the mangosteen peel extract dose of 250 mg was 19.2, and the dose of 500 mg was 18.4. Mangosteen peel extract had an effect on necrotic cells in the islets of Langerhans
The Relationship Between Screen Time Duration And Speech Delay In Children Aged 0-6 Years In Malang City Safira, Safira; Sanjaya, Ayling; Santoso, Anna Lewi
Health Notions Vol 10, No 3 (2026): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Excessive screen time in early childhood can affect various aspects of development, including speech abilities. This study aims to determine the relationship between screen time duration and the occurrence of speech delay in children aged 0–6 years in Malang City. A case–control design was used with a total of 60 children, consisting of 30 children with speech delay and 30 children with normal speech development. Data were collected using a questionnaire measuring daily screen time duration and the Developmental Pre-Screening Questionnaire (KPSP) to assess developmental status. Statistical analysis using the Chi-Square test showed a significant relationship between screen time duration and speech delay (p = 0.000). The findings indicate that children exposed to screen time for more than one hour per day have a higher risk of experiencing speech delay compared to those with limited exposure. These results highlight the important role of parents in supervising and limiting the use of digital media. By reducing screen time and increasing direct interaction, children’s speech and language development can be better supported. This study concludes that managing screen time is a crucial step in preventing speech delay in early childhood
Association Between Serum IL-8 Concentrations and Severity of Knee Osteoarthritis: An Exploratory Cross-Sectional Study Iskak, Iskak; Dewanta, Tunggul Bagus; Santoso, Anna Lewi; Aryanti, Novina; Syahzaqi, Idrus; Njoto, Ibrahim
Jambura Medical and Health Science Journal Vol 5, No 1 (2026): Jambura Medical and Health Science Journal
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jmhsj.v5i1.37399

Abstract

Introduction: Osteoarthritis (OA) is a chronic degenerative disorder of the joints that progresses over time, with inflammation playing a key role in its underlying mechanisms. Interleukin-8 (IL-8), a pro-inflammatory cytokine that participates in immune responses and neutrophil migration, has been associated with the process of cartilage breakdown in OA. This study was conducted to analyze the association between serum IL-8 concentrations and the radiographic severity of knee OA as exploratory evidence to enhance understanding of OA pathophysiology.Method: This exploratory observational research applied a cross-sectional approach in patients diagnosed with knee OA. Seven participants were enrolled through total sampling at the Larasati Pondok Osteoarthritis Elderly Health Center, Faculty of Medicine, Wijaya Kusuma University, Surabaya. Radiographic severity of OA was determined using the Kellgren–Lawrence grading system. Venous blood specimens were obtained to determine serum IL-8 concentrations as an indicator of systemic inflammation.Results: Statistical analysis demonstrated a significant inverse correlation between serum IL-8 concentrations and OA severity (r = −0.866, P = 0.012). These results indicate that IL-8 concentrations in serum are relatively elevated in the early phase of OA and tend to decline as the disease progresses.Conclusion: The findings of this exploratory study indicate that serum IL-8 may represent systemic inflammatory activity during the early stages of knee OA and holds potential as a biomarker candidate for future investigation. Further longitudinal studies involving larger sample sizes are necessary to validate its clinical relevance for OA detection and disease monitoring. Keywords: Cartilage, inflammation, interleukin-8, joint diseases, osteoarthritis, risk factors 
Co-Authors Anggono, Susan Anggono, Susan Jocelyn Aqila Luthfan Ghiralda Arief, Handy Aryanti, Novina Ayling Sanjaya Budiono Raharjo Dewanta, Tunggul Bagus Goein, Amadeus Michel Hamdan, Maulana Muhammad Hisyam I Gede Wisnu Nugraha Ibrahim Njoto Ibrahim Njoto, Ibrahim Idrus Syahzaqi Ira Idawati Iskak Iskak Iskak, Iskak Jemima Lewi Santoso Loo Hariyanto Raharjo, Loo Hariyanto Lutfia Oktaviana Patau Nanda, Karisa Betha Nathania Lisna Ardelia Nur Khamidah Prameswari, Yaasmiin Zivana Regita Prasetyo, Mohammad Yudhi Pratika Yuhyi Hernanda Putri, Diah Arrizah Putri, Made Ayu Prasasti Dwitama Roethmia Yaniari Safira, Safira Sudibjo, Sudibjo Sunarpo, James Hadiputra Tjokro, Vanessa Susanto Tunggul Bagus Dewanta Viskasari P. Kalanjati Wahyuni Dyah Parmasari, Wahyuni Dyah Winoto, Haryson Tondy Yulianti Kuswandari