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All Journal Nurse Media Journal of Nursing Jurnal Biologi Tropis Jurnal Pengabdian Magister Pendidikan IPA ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Kesehatan Tambusai Sasambo Journal of Pharmacy INDRA: Jurnal Pengabdian kepada Masyarakat TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Benzena Pharmaceutical Scientific Journal Parapemikir Jurnal Ilmiah Farmasi
Pratiwi, Eskarani Tri
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Other

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Formulasi Sediaan Emulsi Kombinasi Mikroalga Chlorella sp. dengan Minyak Ikan Gurami (Osphronemus gouramy L.) Utari, Widi Gustita; Alfayzah, Faradillah; Junaida, Alfini; Maharani, Della Shinta; Pratama, Muhammad Imran Ade; Pratiwi, Eskarani Tri
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 7 No. 1 (2024)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v7i1.49670

Abstract

Introduction:. Chlorella sp. is a type of microalgae that has high nutritional value and is often cultivated for various purposes such as medicines or supplements. One of the efforts that can be made to optimize the benefits of Chlorella sp. microalgae with a combination of gourami fish oil formulated in an emulsion reparation. Aims: determine the best formula and physical stability of Chlorella sp. microalgae emulsion with gourami fish oil. Method: making emulsion with varying concentrations of Chlorella sp. microalgae with gourami fish oil (F1= 1:1, F2= 2:1, and F3=3:1). The physical preparation stability test will be carried out such as organoleptic test, homogeneity, pH, viscosity, emulsion type and stability. Results: all three formulas met the requirements for physical evaluation of emulsion preparations, only in the stability test there was separation at F3 (3:1). The type of emulsion produced is oil in water (O/W). Conclusion: the best formula according to the test results is F1 & F2.
Pengaruh Sosialisasi Cek KLIKK BPOM terhadap Tingkat Pengetahuan Pemilihan Kosmetik pada Siswa MTs Al-Hannaniyah NW Praya Fitriana, Mariama; Ridwan, Sucilawaty; Azizah, Hidayatul; Hajrin, Wahida; Subaidah, Windah Anugrah; Pratiwi, Eskarani Tri
TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Vol 5, No 2 (2024)
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33650/trilogi.v5i2.8380

Abstract

Tingginya pertumbuhan industri kosmetik di Indonesia menimbulkan permasalahan berupa munculnya oknum-oknum yang mengedarkan kosmetik secara ilegal. Di antara kelompok yang paling rentan terpengaruh oleh oknum-oknum tersebut adalah kelompok usia remaja. Oleh karena itu, diperlukan sosialisasi kriteria pemilihan kosmetik yang aman, meliputi cek kemasan, label, izin edar, kegunaan, dan kadaluarsa (KLIKK) BPOM sebagai langkah cerdas dalam memilih kosmetik. Penelitian ini bertujuan untuk mengetahui pengaruh sosialisasi cek KLIKK BPOM terhadap tingkat pengetahuan pemilihan kosmetik pada siswa/siswi MTs Al-Hannaniyah NW Praya. Rancangan penelitian menggunakan one group pretest-posttest design dengan metode sosialisasi dan pemberian kuesioner untuk mengukur tingkat pengetahuan responden sebelum dan setelah sosialisasi. Hasil penelitian menunjukkan terdapat peningkatan rata-rata pengetahuan pada responden (P<0,05) setelah sosialisasi, di mana sebanyak 43,3% siswa/siswi memiliki tingkat pengetahuan yang cukup, 40% memiliki tingkat pengetahuan yang tinggi, dan 16,7% memiliki tingkat pengetahuan yang rendah.
Pelatihan pembuatan sabun dari minyak jelantah pada Kader PKK Desa Merembu Subaidah, Windah Anugrah; Hajrin, Wahida; Pratiwi, Eskarani Tri; Ridwan, Sucilawaty
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v5i2.369

Abstract

Indonesian people have a strong preference for food processed using cooking oil. However, the continuous reuse of cooking oil can pose health hazards and have negative environmental impacts if disposed of directly into the soil and waterways. Therefore, innovation is needed to process used cooking oil waste into a product with economic value. Used cooking oil used for cooking can be transformed into soap which is environmentally friendly and has economic value. Hence, this community service aims to reduce the volume of waste cooking oil and improve the local economy. One area in West Nusa Tenggara that has the potential for this product development is the village of Merembu. Out of 2084 families, 727 are still classified as poor. Therefore, there is a need for business opportunities to improve the economy in the village, one of which is by transforming waste cooking oil into soap products. Community service activities in Merembu Village were well received and received positive responses from Empowerment of Family Welfare (PKK) group in Merembu Village. The positive response is reflected in the results of the final evaluation carried out. This activity is a means for PKK group to increase their knowledge of the dangers and methods of processing used cooking oil so that it does not become a pollutant for the environment.
ANALISIS PENJUALAN OBAT OTC UNTUK INDIKASI MAAG dan KONSTIPASI SATU BULAN SEBELUM dan SAAT RAMADHAN di APOTEK AN-NUR rizki, alpa alfi; Pratiwi, Eskarani Tri; Aswal, Dady Syamri
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 1 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i1.7875

Abstract

Selama menjalani puasa ramadan, terjadi perubahan fisiologis dan kegiatan sehari-hari, seperti penurunan energi dan masalah pencernaan seperti maag dan konstipasi. Sehingga pertimbangan pengadaan obat untuk indikasi tersebut harus tetap terkontrol. Penelitian ini menggunakan pendekatan retrospektif dan teknik sampel nonprobabilitas, khususnya Sampling Purposive.Analisis sampel menggunakan perangkat lunak Microsoft excel versi 2021 dengan menguji perbandingan jumlah obat terjual. Hasil menunjukkan penurunan penjualan obat maag sebesar 14% saat puasa, sementara penjualan obat konstipasi meningkat 32%. Namun, penjualan obat maag meningkat 21% satu hari sebelum puasa dibandingkan jumlah tujuh hari sebelumnya. Faktor pemicu maag antara lain perubahan pola makan dan konsumsi makanan berlemak, sementara konstipasi disebabkan oleh perubahan pola makan, kurangnya aktivitas fisik, dan asupan cairan yang rendah. Obat OTC seperti antasida dan pencahar tampaknya menjadi pilihan utama dalam mengatasi masalah maag dan konstipasi selama bulan puasa, yang dapat menjadi pertimbangan dalam strategi pengadaan obat di masa mendatang.
Artikel review : validasi metode penentuan kadar asam retinoat pada sediaan kosmetik dalam bentuk krim dengan menggunakan berbagai instrumen Tanjaya, Steve Pratama; Rosyada, Sabila; Octavia, Ditha Zanetti; Putri, Dewi Angelita; Nadiya, Aisya; Pratiwi, Eskarani Tri
Sasambo Journal of Pharmacy Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v6i1.505

Abstract

Whitening cream cosmetics are widely used to treat skin and are often employed to lighten the complexion of skin and reduce marking. Unfortunately, these products mostly contain hazardous ingredients like retinoic acid, effective yet capable of causing harm with its side effects in terms of skin inflammation, desiccation, and teratogenicity. This review will discuss the evaluation and comparison of the validity of the analytic method in the determination of retinoic acid in cosmetic cream formulations with different instruments; High-Performance Liquid Chromatography, Chromatography-Photodiode Array Detector, and UV-Vis Spectrophotometry methods were discussed. The conducted review used a literature review method wherein various national and international relevant studies of these analytic techniques had been analyzed. Results indicate that HPLC, especially with UV detection, presents the highest accuracy, precision, and sensitivity for quantifying retinoic acid, although it requires a longer analysis time. UV-Vis Spectrophotometry, on the other hand, though less sensitive, offers advantages in terms of simplicity, cost, and shorter duration of the analysis. Among the methods reviewed here, HPLC provides comprehensive validation parameters, demonstrating a linearity of 0.9999, an RSD of 0.99%, an accuracy of 114.3%, an LOD of 0.0165 ppm, and an LOQ of 0.0495 ppm.. Therefore, in order to ensure the safety and regulatory compliance of cosmetic products, the validation of the analytical methodologies for the detection of retinoic acid becomes indispensable, and hence the selection of the most optimal technique is highly relevant.
Optimization of Cream Formula Extract Sargassum Crassifolium Using Varied Concentrations of Glyceryl Monostearate and Triethanolamine Emulgators With The Simplex Lattice Design Method Utari, Weny Syafitri; Pratiwi, Eskarani Tri; Subaidah, Windah Anugrah; Ridwan, Sucilawaty
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9970

Abstract

Sargassum sp. contains bioactive compounds in the form of phenols that have the potential as sunscreen agents in the ultra category, namely 33.2 ± 3.11. The most commonly used formulation for sunscreen products is cream. The purpose of this study was to determine the optimal concentration of glyceryl monostearate and triethanolamine as emulsifiers for Sargassum sp. extract cream, as well as to investigate the physical properties of the optimal Sargassum sp. extract cream formulation. Optimization of the cream formulation was carried out using the Simplex Lattice Design method with Design Expert 13 software, resulting in 8 formulations. The optimal formula obtained was then subjected to physical evaluation, including organoleptic evaluation, homogeneity, and emulsion type. Data analysis used the one-sample t-test method in SPSS version 25. The yield of Sargassum sp. extract was 7.37%. The optimization results showed that the optimal concentration was 7.6% glyceryl monostearate and 0.5% triethanolamine. The optimal cream formulation has good physical properties, namely a soft semi-solid texture, light green color, homogeneity, oil-in-water cream type, pH value of 7.64±0.03, viscosity of 7.626±261.02 cP, adhesive power of 4.37±0.06 seconds, and spreadability of 6.3±0.11 cm. The results of the one-sample t-test statistical analysis of the physical properties of the optimal formulation showed no significant difference from the predicted results, with a confidence level (p>0.05).
The Risk of Diabetic Peripheral Neuropathy among Patients with Type 2 Diabetes Mellitus in Urban and Rural Areas Qona'ah, Arina; Pratiwi, Ika Nur; Pawanis, Zulfayandi; Yamani, Laura Navika; Pratiwi, Eskarani Tri; Nursalam, Nursalam; Ramoo, Vimala
Nurse Media Journal of Nursing Vol 15, No 2 (2025): (August 2025) [In Progress]
Publisher : Department of Nursing, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/nmjn.v15i2.56936

Abstract

Background: Diabetic Peripheral Neuropathy (DPN) is a common complication of type 2 diabetes mellitus (T2DM) and is closely linked to poor glycemic control. However, little is known about how environmental and lifestyle differences between urban and rural settings affect the risk of DPN.Purpose: This study aimed to identify and compare the risk factors of DPN among T2DM patients living in rural and urban areas.Methods: A comparative cross-sectional design with purposive sampling was used to recruit 156 T2DM patients from both urban (Surabaya) and rural (Lamongan) areas of East Java, Indonesia. Data were collected using the Vascular Quality of Life-6 (VQ-6), Diabetic Neuropathy Symptom (DNS), Diabetic Neuropathy Examination (DNE), and Ankle-Brachial Index (ABI). Logistic regression was performed, with a significance level set at p<0.05.Results: The mean age of rural participants was 55.8 years, slightly younger than that of urban participants. Urban residents had higher levels of education (37.7%) but engaged less in regular physical activity (51.9%). The risk of DPN differed significantly between rural and urban participants. Vascular function (ABI, OR = 4.526, range = 0.7–4.00), peripheral nerve symptoms (DNS, OR = 2.838, range = 0–2), neurological deficits (DNE, OR = 1.571, range = 0–5), and neuropathy-related quality of life (VQ-6, OR = 0.663, range = 0–24, p=0.020) were more pronounced among rural participants.Conclusion: Rural T2DM patients are at greater risk of DPN due to vascular and neuropathic complications, combined with sociodemographic disadvantages. These findings highlight the importance of early detection and tailored education programs for rural communities to prevent and manage DPN.
Uji Antiinflamasi Ekstrak Etanol Ashitaba (Angelica keiskei) Secara In Vitro Fitriana, Mariama; Hajrin, Wahida; Subaidah, Windah Anugrah; Ridwan, Sucilawaty; Pratiwi, Eskarani Tri
Jurnal Biologi Tropis Vol. 24 No. 2b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2b.8105

Abstract

Angelica keiskei has potential as an anti-inflammatory agent because it contains chalcone which has been proven to be able to suppress inflammation through inhibiting nitric oxide production and inhibiting the expression of the iNOS and COX-2. The anti-inflammatory potential of Angelica keiskei needs to be tested. This study aimed to determine the anti-inflammatory activity of Angelica keiskei ethanol extract using the protein denaturation inhibition method. Angelica keiskei was extracted using the sonication method with 96% ethanol. The extract was tested for anti-inflammatory activity using the protein denaturation inhibition method with diclofenac sodium as a positive control. The percent of inflammatory inhibition is used to assess sample activity. The results showed that the percent of inflammatory inhibition of Angelica keiskei ethanol extract increased as the test concentration increased. The maximum percent inhibition was obtained at a concentration of 1.5% with the percent of inflammatory inhibition value of 23.14% ± 0.05. Angelica keiskei ethanol extract has anti-inflammatory activity based on in vitro testing using the protein denaturation inhibition method.
Formulation and Evaluation of Moringa Leaf Ethanol Extract Emulgel and its Effectiveness Test Against Staphylococcus aureus Raissa, Talitha Hasna; Pratiwi, Eskarani Tri; Hidayati, Agriana Rosmalina
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8218

Abstract

Moringa leaves (Moringa oleifera Lamk.) have Tannin compounds which are secondary metabolites as antibacterial. The purpose of this study is to determine the antibacterial properties of ethanol extract from moringa leaves against Staphylococcus aureus. The research methods began with the extraction of Moringa leaves using sonication with 96% ethanol as the solvent, followed by testing the antibacterial effectiveness of the extract at concentrations of 5%, 10%, and 20%. The extract concentration with the best inhibition zone diameter was formulated into an emulgel, followed by physical evaluation of the formulation and testing its effectiveness against Staphylococcus aureus. The bacterial inhibition zone was measured to determine the antibacterial level of the extract and emulgel formulation. The results of antibacterial effectiveness were evaluated using the One Way ANOVA test with a confidence level of 95%. The yield of the extract was found to be 13.05%. The inhibition zone diameters for the ethanol extract of Moringa leaves at concentrations of 5%, 10%, and 20% were 4.8 mm, 5.3 mm, and 8.1 mm, respectively. The physical evaluation of the ethanol extract emulgel formulation met the criteria for a good emulgel. The emulgel containing 4% ethanol extract from Moringa leaves produced an inhibition zone diameter of 4.8 mm, indicating weak antibacterial effectiveness. There was a significant difference between the treatment groups according to the results of the One Way ANOVA test with a significance value (p=0.000). This study found that Moringa oleifera leaf ethanol extract has the ability as an antibacterial; however, its effectiveness decreases when formulated into an emulgel, likely due to the reduction in extract concentration in the final formulation.
Optimization of Eye Shadow Powder Formula Preparation of Buni Fruit Extract (Antidesma bunius L. Spreng) as Natural Dye Lestari, Neli Aulia; Hajrin, Wahida; Pratiwi, Eskarani Tri
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10140

Abstract

The use of synthetic dyes in cosmetics can cause side effects such as allergies. Therefore, the presence of natural dyes such as anthocyanins from berries is a safer alternative for the community. However, the stability of anthocyanins as natural dyes can be affected by pH. The purpose of this study was to determine the optimum concentration of citric acid and tartaric acid in eyeshadow powder preparations as pH stabilizers using the Simplex Lattice Design method. The research method used the sonication method. Then, the formulation results from running SLD were carried out and evaluated for particle size, adhesiveness, and pH. Data analysis used SLD to obtain the optimum formula. Then, the evaluation was carried out as before with additional evaluations of organoleptic tests, homogeneity and polish. Furthermore, the data were verified statistically with a one-sample t-test. The results obtained an extract yield of 22.9% and a positive anthocyanin content. Based on the SLD method, the optimum formula was obtained with a citric acid concentration of 1.49% and a tartaric acid concentration of 0.508%. Verification of the optimum formula showed no significant difference between the experimental response and the predicted response with a pH value of 5.75 ± 0.12; adhesive power of 11.66 ± 1.52%; and particle size of 126.32 ± 2.02 μm. The conclusion is that the optimum formula produces good physical characteristics and the verification results show agreement between the predicted response and the experimental results.
Co-Authors Alfayzah, Faradillah Aswal, Dady Syamri Azizah, Hidayatul Candra Eka Puspitasari Fitri, Maulida Khalila Fitriana, Mariama Hajrin, Wahida Hidayati, Agriana Rosmalina Ika Nur Pratiwi Junaida, Alfini Laura Navika Yamani Lestari, Neli Aulia Maharani, Della Shinta Manafe, Deary Pretty Genovani Murniati Salam, Mahra Nadiya, Aisya Nursalam Nursalam Octavia, Ditha Zanetti Pawanis, Zulfayandi Pratama, Muhammad Imran Ade Putri, Dewi Angelita Qona'ah, Arina Raissa, Talitha Hasna Ramoo, Vimala Ridwan, Sucilawaty rizki, alpa alfi Rosyada, Sabila Salam, Mahra Murniati Setyowati, Kirana Ayu Tanjaya, Steve Pratama Utari, Weny Syafitri Utari, Widi Gustita Widyasari, Ni Luh Ayu Sri Windah Anugrah Subaidah Yustitia, Nur Tahany Yustitia, Nurtahany