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All Journal Jurnal EMT KITA Teknika International Journal of Economics, Management, Business, and Social Science International Journal of Educational Review, Law And Social Sciences (IJERLAS) International Journal Software Engineering and Computer Science (IJSECS) Outline Journal of Management and Accounting Jurnal Farmasi Indonesia Lex Prospicit International Journal of Mechanics, Energy Engineering and Applied Science (IJMEAS) Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Caroline
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How Do Entrepreneurship And Spillover Knowledge Affect Economic Growth? Lestari, Etty Puji; Caroline; Rahayu, Heffi Christya
INTERNATIONAL JOURNAL OF ECONOMICS, MANAGEMENT, BUSINESS, AND SOCIAL SCIENCE (IJEMBIS) Vol. 5 No. 1 (2025): January 2025
Publisher : CV ODIS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59889/ijembis.v5i1.457

Abstract

Policy on restricting community activities at this time of the pandemic has made entrepreneurs make breakthrough innovations through online sales using the internet. Entrepreneurship spillover knowledge through the internet when selling their business. The purpose of this study is to analyze entrepreneurship and its effect on the economic growth of Central Java. This study adopts Romer's endogenous economic growth model using the Manhattan Distance spatial weight matrix with K-Near Neighbor to calculate LISA and the scatter plot matrix. The study results show the role of self-employed vocational graduates or workers undertaking entrepreneurial efforts in Central Java Province as Micro, Small, and Medium Enterprises (MSMEs). Vocational graduates have a stock of knowledge to share with others in the form of spillover technology for internet use in online sales. Internet use during the pandemic in Central Java Province, especially in online sales in the food and beverage industry, is dominant. The restricting social activities and the work-from-home policy encourage people to make transactions to sell goods or services and purchase goods or services online.
Uji Aktivitas Analgesik Tablet Asam 4-(Klorometil)Salisilat pada Mencit Putih dengan Metode Writhing Test dan Hotplate Tiffany, Angela; Ribka Abiati, Meidelin; Foe, Kuncoro; Tjahjono, Yudy; Caroline; Esar, Senny Yesery; Hadinugroho, Wuryanto
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 1 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (507.738 KB) | DOI: 10.35617/jfionline.v14i1.78

Abstract

Acetylsalicylic acid is an analgesic drug that still popularly used. However, acetylsalicylic acid may result undesirable side effect of gastrointestinal as it can cause gastric ulcer to bleeding. Previous research has succeeded synthesizing new compound derived from salicylic acid, namely 4-(chloromethyl)salicylic acid which has the potential to reduce its side effects with a better pharmacological effects than acetylsalicylic acid. In its development, the formulation of the compound in tablet dosage form has been carried out. However, until now there has not been a pharmacological test to determine whether it still provides a greater effect than acetylsalicylic acid after being formulated. This study is to test the analgesic activity of 4-(chloromethyl)salicylic acid tablets in albino mice using writhing test and hotplate methods. Analgesic activity test using the hotplate method was carried out on albino mice which given the suspension of the tablet sample and the observations were made in a periodic of time. Analgesic activity test using writhing test method was carried out in 0.6% acetic acid-induced albino mice, where the suspension of the tablet was administered 30 minutes before administration of acetic acid. Analgesic activity was assessed by counting the number of writhings, and the results were statistically compared with one-way ANOVA. Tests were also performed on acetylsalicylic acid as a positive control and suspension as a negative control group.  There were significant differences (P<0.05) of the analgesic activity observed among groups. Both methods show that 4-(chloromethyl)salicylic acid tablets provide stronger analgesic activity than acetylsalicylic acid.
Performance Evaluation of a Hybrid Solar Panel and Thermoelectric Generator (TEG) System with Copper Plate Enhancement on the Hot Side Bayusari, Ike; Ronting, Virgie Claudia; Soraya, Ayu; Caroline; Hermawati; Rahmawati
International Journal of Mechanics, Energy Engineering and Applied Science (IJMEAS) Vol. 3 No. 2 (2025): IJMEAS - May
Publisher : Yayasan Ghalih Pelopor Pendidikan (Ghalih Foundation)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53893/ijmeas.v3i2.409

Abstract

The utilization of solar energy is commonly achieved through solar panels; however, heat dissipation from the panels often reduces their overall efficiency. A hybrid system combining solar panels and thermoelectric generators (TEGs) offers a potential solution to this issue. To enhance the temperature difference (∆T) across the TEG, a metal plate can be added to the hot side, while a heatsink is applied to the cold side. This study investigates the performance of three prototype configurations: a 2.4 Wp monocrystalline solar panel integrated with a TEG module, with variations in the addition of a copper plate, an aluminum plate, and no plate on the TEG hot side. Experimental results demonstrate that the prototype with a copper plate yielded the highest average values, with a ∆T of 8.63 °C, voltage of 11.57 V, current of 0.17 A, and power output of 2.02 W. In comparison, the aluminum plate prototype achieved a ∆T of 6.11 °C, voltage of 11.57 V, current of 0.16 A, and power output of 1.71 W, while the prototype without any plate produced a ∆T of 5.80 °C, voltage of 10.79 V, current of 0.15 A, and power output of 1.63 W. Among all tested configurations, the copper plate prototype exhibited superior performance, attributed to the high thermal conductivity of copper, which significantly enhances the ∆T across the TEG, thereby increasing electrical output.
STRATEGIES AND IMPROVEMENT PRIORITIES AGAINST CONSTRAINTS IMPLEMENTATION OF ROUNDTABLE ON SUSTAINABLE PALM OIL (RSPO) AT PT XYZ PKS C Caroline; Sukaria Sinulingga; Meilita Tryana Sembiring
International Journal of Educational Review, Law And Social Sciences (IJERLAS) Vol. 4 No. 5 (2024): September
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ijerlas.v4i5.1948

Abstract

The Roundtable on Sustainable Palm Oil (RSPO) is a global non-profit organization that focuses on developing and implementing global standards for sustainable palm oil that has a responsibility to protect animals, environments, workers and local communities. PT XYZ – PKS C has obtained RSPO certification on June 13th, 2023. The research objectives are: 1) finding out the obtacles faced in the implementation of RSPO; and 2) looking for effective strategies to overcome the negative impacts of these obstacles. Research was conducted using qualitative and quantitative methods through interviews and AHP (Analytical Hierarchy Process) questionnaires. Results obtained: 1) PT XYZ realizes that the obstacles faced in the adoption of RSPO include: a) Limited Capability and Number of Human Resources, b) Limited Budget Funds/Costs, c) Lack of Coordination and Consultation communication, and d) Legal Regulations; 2) Priority for resolving operational obstacles in implementation of RSPO, including: a) Level 1: Planet, b) Level 2: Principle 2 and 6; 3) Strategies that can be implemented by PT XYZ to overcome obstacles, including: a) following ISO 14001:2015 and ISO 9001:2015 certification; b) Consulting with sustainability teams from other palm oil companies; c) Design a buffer area by planting plants consumed by long-tailed monkeys.
Pengaruh Gugus Hidroksi pada Sintesis Senyawa 4,4’-Dihidroksibenzalaseton dan Aktivitasnya sebagai Antioksidan Jessica, Maria Anabella; Budiati, Tutuk; Caroline
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 12 No. 1 (2025): March
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v12i1.7201

Abstract

Dibenzalacetone and their derivatives, , 4,4’ dihydroxydibenzalacetone are curcumin analogs that have antioxidant activity. The effect of hydroxyl group on the synthesis reaction is proven by comparing the synthesis results yield of dibenzalacetone with 4,4’-dihydroxydibenzalacetone. Both compounds are synthesized through the Claisen-Schmidt condensation reaction using sodium hydroxide as the catalyst. The synthesis results were tested for purity by melting point tests and thin layer chromatography, and structure identification tests were carried out using infrared spectrophotometry. The results of the study showed that the percentage yield of dibenzalacetone was greater than 4,4’-dihydroxydibenzalacetone, which was 67.29% and 24.51%, respectively. The presence of hydroxyl groups can increase the density of the benzene ring and facilitate the reaction of the carbonyl group of 4-hydroxybenzaldehyde, including the Cannizaro reaction. The Cannizaro reaction can occur in aldehyde compounds without alpha hydrogen, such as benzaldehyde, where some of the aldehyde will undergo oxidation and some will undergo reduction. As a result, the amount of aldehyde that reacts with acetone decreases so that the yield obtained is lessthan dibenzalacetone. Antioxidant testing was carried out using the DPPH method and expressed as an IC50 value, then compared with curcumin and vitamin C. Although it does not show greater antioxidant activity than curcumin or vitamin C, the presence of hydroxyl groups in 4,4' dihydroxydibenzalacetone can increase antioxidant activity compared to dibenzalacetone which does not have a hydroxyl group. This is proven by the IC50 value of the compound 4,4'-dihydroxydibenzalacetone which is lower than dibenzalacetone, which is 3.9588 mM and 66.5503 mM, respectively.
Co-Authors Aat Ruchiat Nugraha Andrijanni Aninam, Johny Anshori, M Isa Bambang Sutejo, Bambang Calosa, Charen Esar, Senny Yesery Etty Puji Lestari Foe, Kuncoro Hasian, Clarisa Permata Heriman, Amanda Regina Pallas Hermawati Ike Bayusari Imam Hanafi Jessica, Maria Anabella Jesslyn Johan alexander, Johan Kosasih, Jocelin Lestari, Wulan Sri Meilita Tryana Sembiring, Meilita Tryana Muhammad Yusuf Ariyadi Naibaho , Novia Nazaruddin, Erizal Oroh, Oliviane Pada, Damir Putro, Suryati Eko Rahmawati Ribka Abiati, Meidelin Rofi'i, Yulianto Umar Ronting, Virgie Claudia Saragih, Yuni Marlina Soraya, Ayu Stefanie Sudirman Sukaria Sinulingga Sulistyawati, Upik Sri Sumiati, Siti Susbiyantoro, Susbiyantoro Tanelwy, Aurellia Tiffany, Angela Tina Muhardika Handayani Tjahjono, Yudy Tobing, Ega Yolanda Lumban Trisolvena, Muhammad Nana Tutuk Budiati Wuryanto Hadinugroho Yuswardi