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All Journal Jurnal Kedokteran Brawijaya Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Medical and Health Science Journal Jurnal Pengabdian Masyarakat Bumi Raflesia Bubungan Tinggi: Jurnal Pengabdian Masyarakat Nommensen Journal of Medicine Jurnal Kesehatan dan Pembangunan Cermin Dunia Kedokteran
Erik Jaya Gunawan
Medical Doctor Profession Study Program, School Of Medicine, Universitas Ciputra Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Modification of qSOFA Increases Mortality Prediction Accuracy in Sepsis Patients Gunawan, Erik Jaya; Siahaan, Salmon Charles Pardoman Tua; Idarto, Areta; Pribadi, Florence; Handayani, Lidya
Jurnal Kedokteran Brawijaya Vol. 33 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.3

Abstract

The Quick Sequential Organ Failure Assessment (qSOFA) is a simple parameter, however, its sensitivity as a mortality predictor is low. This study aimed to improve the predictor performance of qSOFA for in-hospital mortality. This study was a retrospective single-centered cohort using medical record data. This study included 150 patients aged 18-80 years old, who experienced sepsis and received ICU care between September 2021 and August 2022. qSOFA and modified ROX index (mROX) were calculated based on the most severe condition recorded in the emergency department (ED). Each variable's area under the receiver operating characteristic (AUROC) curve, sensitivity, and specificity were compared to predict in-hospital mortality. qSOFA scores ≥2 and mROX values ≤3.20 were independent factors that increased the risk of in-hospital mortality (OR 3.69 and 21.50; p 0.004 and 0.005, respectively). The combination of qSOFA scores ≥2 and mROX value ≤3.20 as in-hospital mortality predictors resulted in AUROC 0.791 with a sensitivity of 71.7% and specificity of 75.7%. The AUROC, sensitivity, and specificity of the combination of qSOFA and mROX were higher than qSOFA (0.766, 70.8%, 70.3%) or mROX (0.760, 68.1%, 67.6%) alone. In conclusion, the combination of qSOFA scores ≥2 and mROX values ≤3.20 increase the sensitivity and specificity for predicting in-hospital mortality in sepsis patients.
Co-Authors Areta Idarto Arisanti, RR Shinta Aura Dhiya Ulhaq Bimo Sasono Bueya, Eirene Putri Febriani Pratama David Ferdinandus Denys Putra Alim Etha Rambung Farica Sutantoyo, Felisitas Felisitas Farica Sutantoyo Florence Pribadi Fransisca Suyanto Pangemanan Ihyan Amri Imelda Ritunga Isnaini Isnaini Lidya Handayani Natalia Yuwono Raden Roro Shinta Arisanti Salmon Charles P.T. Siahaan Salmon Charles Pardomuan Tua Siahaan Samantha Debora Ang Santosa, Rahajoe Imam Setyawan, Yuswanto Siahaan, Charles Siahaan, Salmon Charles P. T. Siahaan, Salmon Charles Pardoman Tua Stefani Nurhadi Stephanie Laurensia Budi Tjiptohardjo, Andianto Indrawan Vincent Aurelius Wilhelmus Alvin Kaka Yohan Christian Suisan Yohan Christian Suisan