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All Journal Jurnal Surya Medika Jurnal Peduli Masyarakat Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Innovation Research and Knowledge Inovasi Jurnal Pengabdian Masyarakat (IJPM) Awal Bros Journal of Community Development Science and Community Pharmacy Journal
Aldila, Silvy
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Journal : Science and Community Pharmacy Journal

 1 
Stability Testing Occurred On Piroxicam Cream Preparation By Using Stearic Acid And Triethanolamine As Emulsifying Agents Aldila, Silvy; Girsang, Valentina; Rahmawati, Ina Sonia; Maharai, Daniel; Sa’adah, Anifatus
Science and Community Pharmacy Journal Vol. 2 No. 2 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i2.482

Abstract

Preface: Piroxicam is classified as a Class 2 product in the Biopharmaceutic Classification System due to its limited solubility in water. The cream preparations underwent optimisation of the stearic acid and triethanolamine concentrations. The optimisation results indicate that the most favourable amounts of stearic acid and triethanolamine (TEA) are 16% and 4% respectively. The physical attributes test yielded positive findings for the formula, indicating a successful cream formulation that satisfied the specified criteria. Purpose: The cream formulation is thereafter submitted to a stability assessment. The purpose of the stability test is to ascertain the long-lasting quality of the preparation when subjected to various storage circumstances. Procedure: Stability tests were conducted over 6 cycles at temperatures of 4° C and 40° C. During the testing phase, various characteristics of the cream preparation were assessed, including organoleptic properties, homogeneity, viscosity, adhesive power, spreadability, and pH. Result: The formulated solution successfully fulfils the criteria of the physical characteristics test, with the following parameter values: pH of 6.8, viscosity of 11010 Cps, spreading power of 6.8 cm, adhesive power of 2.6 seconds, and protective power of 6.5 seconds. Conclusion: The t-test findings conducted before and after assessing the stability of the preparation indicated a p-value greater than 0.05, indicating the absence of a significant difference.
BROCCOLI (Brassica oleracea L) ETHANOL EXTRACT: A MOISTURIZER AND ITS EVALUATION IN ASPECTS OF PHYSICAL CHARACTERISTICS Aldila, Silvy; Puruhita, Ranatri; Uliana, Syahkhirotul Exma; Sa’adah, Anifatus; Gloria, Fransisca
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.545

Abstract

Skin disorders that are dry, dull, scaly, and not fresh affect everyone. Moisturizing cream is a cosmetic product that effectively hydrates and improves dry skin. Broccoli, scientifically known as Brassica oleracea L, is rich in vitamin C components, vitamin E (α-tocopherol), and flavonoids, which act as natural antioxidants and provide moisturizing properties for the skin. Producing extracts by the maceration process. Broccoli extract is utilized in the formulation of four moisturizing cream preparation compositions, each with a concentration of F1 (0%), F2 (2%), F3 (3%), and F4 (4%). The moisturizing cream formulation is assessed for its physical properties. Conducting tests to evaluate the dosage characteristics of moisturizing creams, includes organoleptic testing, homogeneity testing, pH testing, dispersion testing, adhesion testing, and viscosity testing. The concentration of broccoli extract in the four moisturizing cream preparation formulations is as follows: F1 (0%), F2 (2%), F3 (3%), and F4 (4%). The moisturizing cream formulation is assessed for its physical properties. Conducting tests to evaluate the dosage properties of moisturizing creams, including sensory evaluation, uniformity assessment, pH measurement, dispersion analysis, adhesion examination, and viscosity measurement
An Irritation Test of Optimum Preparation of Celery Extract Face Clay Cleanser With Sodium Lauryl Sulfate (SLS) and Cocamidopropyl Betaine (CAPB) as Surfactants: Irritation Test of Optimum Preparation of Celery Extract Face Clay Cleanser With Sodium Lauryl Sulfate (SLS) and Cocamidopropyl Betaine (CAPB) as Surfactants Bunga Eloystina, Laurencia Julia; Aldila, Silvy; Girsang, Valentina; Sa'adah, Anifatus
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.580

Abstract

Surfactant is one of the important things in making face clay cleanser preparations. Sodium Lauryl Sulfate (SLS) is an anionic type surfactant that is often used in cosmetic products. The use of Sodium Lauryl Sulfate (SLS) can cause irritation and dry skin. Combination with cocamidopropyl betaine (CAPB) which is amophoteric can reduce skin irritation. Based on this, a safety test is needed which aims to meet the preparation requirements before being marketed to the wider community. One of the safety tests that can be done is the skin irritation test. The test method used is the human patch test. The irritation test of the optimum preparation of face clay cleanser celery herb extract (Apium graviolens L.) with a concentration of 0.5% SLS and 9.5% CAPB was carried out on 6 volunteers consisting of men and women aged 20-35 years, the score of the degree of irritation was 0, which means that the preparation is not irritating. Based on the evaluation with SPSS, it can be concluded that there is no significant difference (p>0.05) for the irritation test results and the optimum preparation of celery herb extract face clay cleanser (Apium graviolens L.) meets the safety requirements.
Co-Authors Adrianto, Madyo Alfiyaturrakhma, Untsa Arini, Yovita Dwi Ariyani, Destiana Putri Bunga Eloystina, Laurencia Julia Dahliyanti, Novita Dwi Desi Soraya Girsang, Valentina Gloria, Fransisca Hardiyati, Siti Farah Maharai, Daniel Naulita Sidauruk, Viony Ni Made Ayu Wulansari Nurainy, Farah Destyana Nurhanifah, Tia Nurwidianingsih, Silvia Puruhita, Ranatri Putri Maharani Rahmawati, Ina Sonia Rizki Al Farizi, Gilang Rizky Budi Santoso Sa'adah, Anifatus Saadah , Anifatus Sa’adah, Anifatus Suksi Riani Tri, Elin Tunik Saptawati Uliana, Syahkhirotul Exma Ummi Kalsum