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All Journal Biofaal Journal Munggai: Jurnal Ilmu Perikanan dan Masyarakat Pesisir Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Innovative: Journal Of Social Science Research Jurnal Pengabdian Masyarakat Bangsa PCJN Pharmaceutical and Clinical Journal of Nusantara Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran Journal of Health Science and Medical Therapy INSANTA: JURNAL PENGABDIAN KEPADA MASYARAKAT WASATHON Tolis Mengabdi : Jurnal Pengabdian Kepada Masyarakat BATOBO: Jurnal Pengabdian Kepada Masyarakat Pasapua Health Journal Jurnal Sains, Teknologi dan Kesehatan Medicor : Journal of Health Informatics and Health Policy BAKTI : Jurnal Pengabdian Kepada Masyarakat JHN: Journal of Health and Nursing Journal of Biomedical Sciences and Health
Ukratalo, Abdul M
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The Potential of Ethanol Extract from Langsat Leaves (Lansium Domesticum Var. Pubescent) In Controlling Aedes Aegypti Mosquitoes: A Study on The Effectiveness of Natural Substances as Mosquito Repellents Ukratalo, Abdul M; Ichsan, Muhammad Nurhidayat; Kaihena, Martha; Manery, Dodikrisno Ekaputra; Pangemanan, Victory Osvaldo; Moniharapon, Debby Dijola
Journal of Biomedical Sciences and Health Vol. 1 No. 1 (2024)
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/jbsh.v1.i1.1

Abstract

In recent decades, attention to the utilisation of natural materials as alternatives in vector control has increased. One potential source that needs to be explored is langsat leaves, which are known to have active compounds. Ethanol extracts of langsat leaves may contain compounds that can provide control effects against Aedes aegypti mosquito larvae. This study aims to assess the effectiveness of the ethanol extract of langsat leaves in controlling Aedes aegypti mosquitoes, the vector of Dengue Fever disease. The extraction method was carried out using the maceration technique with ethanol as the solvent. Bioactivity test was conducted through larvicidal bioassay against Aedes aegypti larvae. The results showed that the ethanol extract of langsat leaves has a larvicidal effect against Aedes aegypti mosquito larvae. The toxicity levels, both LC50 and LC90, indicate that the ethanol extract of langsat leaves has potential as a mosquito larva control agent.
Reproductive Health Optimization: Remarkable Benefits of Avocado Juice (Persea americana P. Mill) in Enhancing Production and Reducing Spermatozoal Abnormalities in Mice Exposed to Clove Cigarette Smoke Kaihena, Martha; Ukratalo, Abdul M; Pangemanan, Victory O; Manery, Dodikrisno E
Journal of Biomedical Sciences and Health Vol. 1 No. 1 (2024)
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/jbsh.v1.i1.2

Abstract

Background: Cigarette smoke has the potential to disrupt hormonal balance, affect spermatogenesis processes, damage spermatozoa viability, and create the presence of toxic substances in spermatozoa. On the other hand, avocados contain protein and various vitamins, such as A, B, B1, B2, E, and C, as well as other substances, such as beta-carotene, linoleic acid, lecithin, calcium, iron, pantothenic acid, potassium, phosphorus, niacin, and natural plant oils. Vitamins C and E in avocados are believed to increase the number of Leydig cells and spermatozoa. Objective: This study aims to evaluate the potential of avocado juice to improve reproductive health in mice exposed to kretek cigarette smoke. Methods: Male mice (Mus musculus) aged 2 months, weighing ±20g each, were divided into 5 randomly assigned groups: K- (control without treatment), K+ (positive control exposed to cigarette smoke), P1 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.5 ml/20 g BW), P2 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.7 ml/20 g BW), and P3 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.9 ml/20 g BW). Cigarette smoke exposure was conducted for 14 days. Results: The results showed that regular avocado juice consumption could increase sperm production and reduce spermatozoa abnormalities in mice exposed to kretek cigarette smoke. Conclusion: The clinical implications of these findings may contribute to a better understanding of avocado juice's potential as a supplement to improve reproductive health, especially in the context of kretek cigarette smoke exposure.
Potential Bark Cinnamomum burmanii in Regenerating Damaged Liver Cells of Mice (Mus musculus) Diabetes Mellitus Model Ukratalo, Abdul M; Kaihena, Martha; Sirait, Dion P O; Pattimura, Nadira; Manery, Dodikrisno Ekaputra
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 02 (2023): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (752.864 KB) | DOI: 10.58549/pcjn.v2i01.58

Abstract

Diabetes mellitus is a chronic disease that can quickly increase the prevalence of complications in sufferers, such as liver damage. This study aims to examine the effect of methanol extract cinnamon bark (Cinnamomum burmanii Bl) in regenerating liver cell damage mice (Mus musculus) Diabetes Mellitus through the histological picture. 20 mice were divided into 5 groups which consisted of a negative control group, Positive control and a group of mice that were given methanol extract bark Cinnamomum burmannii dose of 125 mg/head/day, 250 mg/head/Day and 500 mg/head/day. In the positive control group and the group of mice that will be given extract streptozotocin injected dose of 0.2 ml and observed blood sugar levels if sugar levels have increased then given methanol extract bark Cinnamomum burmannii with a dose that has been determined and blood sugar levels were measured. On the last day, surgery is performed to remove the liver, after which histological preparations are made. The results showed that the administration of bark extract Cinnamomum burmanii can regenerate damaged liver cells of mice due to diabetes mellitus. This is due to the content of secondary metabolite compounds contained in the bark of Cinnamomum burmannii.
Co-Authors Amos Killay Assagaf, Abdur Rahman Barcinta, Muhammad Fahrul Basyarewan, Eko Saputra N Buranga, Edwin Ciputra, Dmytrick Efraim Samson, Efraim Embisa, Yushar A Handy Erwin Pier Leimena Ichsan, Muh. Nurhidayat Ichsan, Muhammad Nurhidayat Kaliky, Arief Rahman S La Eddy Loilatu, Muhammad Fitrah Mainassy, Meilissa C Manery, Dodikrisno E Manery, Dodikrisno Ekaputra Martha Kaihena Moniharapon, Debby Dijola Moniharapon, Mechiavel Muhammad, Alfaro Nadira Pattimura Nanere, Bill E Pagaya, Joseph Palembang, Citra Fathia Pangemanan, Victory O Pangemanan, Victory Osvaldo Pieter Kakisina Ramadhany, Muhammad R Ramadhany, Muhammad Reza Seumahu, Cecelia Anna Sirait, Dion P O Syuaib, Achmad Tuhumuri, Evelin Tuhumury, Fiyogi D A Wakanno, Ferros Rozik