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Journal : Respiratory Science

Association Between Factory Workers’ Profile with Chest X-ray Finding and Spirometry at Industrial Company of X Wijaya, Dewi; Esha, Indi; Adrianison, Adrianison; Simatupang, Elvando Tunggul Mauliate; Amarudin, Amarudin
Respiratory Science Vol. 6 No. 1 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i1.198

Abstract

Background: Factory workers are a group at high risk of developing occupational lung abnormalities. Continuous exposure to dust, smoke, or gas particles during work processes may lead to progressive lung damage. Chest X-ray and spirometry are essential diagnostic tools for assessing both structural and functional lung changes, allowing early detection and prevention of occupational lung disability, especially among workers exposed to airborne pollutants. Method: This analytical observational study employed a cross-sectional design to analyze the association between factory workers’ profiles and chest X-ray and spirometry findings. Lung function was assessed using spirometry parameters, including Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV₁), and FEV₁/FVC ratio to identify restrictive or obstructive patterns. Data were collected using total sampling during periodic health examinations and analyzed with SPSS version 26.0. Descriptive statistics were used to summarize characteristics, while inferential analysis using Chi-square or Fisher’s exact tests was conducted to determine associations between categorical variables, with a significance level set at P<0.05. Results: A total of 260 factory workers participated, most with ≤5 years of work experience (60.76%). Comorbidities were significantly associated with both chest X-ray findings and lung function (P=0.034 and P=0.004). Smoking history and length of work also showed significant relationships with lung function (P=0.027 and P=0.019). Conclusion: There is a significant association between smoking history and length of work with changes in lung function. Meanwhile, comorbidities have a significant association with lung structure and lung function. Periodic evaluation using spirometry and chest X-ray is essential for early detection and prevention of occupational lung abnormalities among factory workers.
Lung–Kidney Interactions: Impact for Systemic Disease Simatupang, Elvando Tunggul Mauliate; Wijaya, Dewi; Sembiring, Ligat Pribadi
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.199

Abstract

Lung–kidney interaction is increasingly recognized as an important determinant of prognosis in systemic and critical illnesses. This is physiologically based and often occurs in daily medical practice. Evidence shows that dysfunction in one organ may trigger or worsen injury in the other, making this relationship relevant in clinical assessment and therapeutic decision-making. Understanding this bidirectional interaction is essential, as it influences disease severity, treatment response, and mortality. Direct or indirect, lung–kidney interactions are frequently observed in clinical practice. Hypercapnia, hypoxemia, and systemic inflammatory response are among many factors that can induce renal involvement in lung disease. Between lung complications and kidney function abnormalities, there is a correlation, such as pulmonary edema, pleural effusion, chronic kidney disease and acute kidney injury. The patients of acute kidney injury and chronic kidney disease may be more susceptible to lung issues due to several internal risk factors, including uremia, metabolic acidosis, electrolyte imbalances, and volume overload or increased fluid volume. Other external risk factors that also contribute to lung issues include systemic inflammation and oxidative stress. Occupational and environmental exposures may also contribute to lung disease, and indirectly accelerate renal function decline.  Despite clinical relevance, lung–kidney interactions remain underrecognized in autoimmune diseases.