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Asseggaf, Syarifah Nurul Yanti Rizki Syahab
Departemen Farmakologi, Fakultas Kedokteran, Universitas Tanjungpura, Pontianak, Indonesia
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Journal : Jurnal Fitofarmaka Indonesia

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AKTIVITAS ANTIJAMUR EKSTRAK ETANOL DAUN KESUM (Polygonum minus Huds.) TERHADAP Microsporum canis Vica Vionita Rosalim; Syarifah Nurul Yanti Rizki Syahab Asseggaf; Diana Natalia; Mahyarudin Mahyarudin
Jurnal Fitofarmaka Indonesia Vol 6, No 2 (2019): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.079 KB) | DOI: 10.33096/jffi.v6i2.470

Abstract

Dermatophytosis is a fungal infection caused by one of the superfixial mycoses, namely dermatophytes. Microsporum canis is one of the dermatophyte species that can infect hair, skin, leg and thighs. Kesum plants (Polygonum minus Huds.) are endemic plants of West Kalimantan that have many bioactive compounds from the roots to the leaves. The leaves of kesum contain secondary metabolites which can inhibit fungi growth. This research had purpose to know  the antifungal activity of kesum leaves’ ethanol extracts on Microsporum canis. The kesum leaves’ extraction  used maceration method with 96% ethanol as a solvent. Analysis secondary matbolites of kesum leaves’ secondary metabolites used tube test and thin layer chromatography. Antifungal activity test used Kirby-Bauer disk diffusion method with 5 extract concentration variantions i.e. 80, 40%, 20%, 10%, and 5%. Itraconazole 8 µg/disk was used as a positive control and DMSO 10% was used as a negative control. Kesum leaves’ ethanol extract was obtained saponin, flavonoid, alkaloid, therpenoid, and phenol. Ethanol extracts of kesum leaves did not create zone of inhibition against Microsporum canis. Ethanol extracts of kesum leaves didn’t have antifungal activity against Microsporum canis.
Co-Authors Agustina Arundina Triharja Tejoyuwono, Agustina Arundina Triharja Agustina, Vanisia Ainun Najib Febrya Rahman Alfazon, Rohid Anzas Niam Saputra Athira Syafika Chally Liadylova Putri Changestu, Daniel Alexander Dewi, Dyan Roshinta Laksmi Diana Natalia Diana Natalia Diana Natalia Fahdi, Faisal Khalid Fahiratunnisa, Namira Alifah Fatriona, Emitra Gama - Natakusumawati Hafizuddin, Muhammad Haryati Septiani Hendrayana, Bimo Irvandy, Muhammad Syifa Kalahan, Al Munawar Khansa, Marsyabila Puspa Khansa, Masyabila Puspa Len, Jenny Firda Liauw, Josephine Johan Mahyarudin, Mahyarudin Mardhia Mardhia Mistika Zakia Mistika Zakiah Muhammad Luthfi Musawaris, Risa Febriana Nur, Andi Denisa Fadliah Nur, Fina Herlinda Nurmainah Nurmainah Nurmainah Priyono, Djoko Puji Astuti Putra, Galih Abisatya Hartono Putri, Triyana H. Qatrunnada, Aura Rahmaddani, Metta Sintia Ramaita, Ramaita Refaldi, Muhammad Wildan Ridha Ulfa Ridha Ulfah Risa F. Musawaris Sari Rahmayanti Seprian, Dwin Sri Purwanti Supianto, M. Jahari Tanti Melinda Triyana Harlia Putri Tyas, Tri Wahuning Tyas, Tri Wahyuning Vanesa - - Vanesa, Vanesa Veren Evelyn Chandra Veren Evelyn Chandra Vica Vionita Rosalim Wahyudi, Dery Windesi, Yubelina Yuannefa, Nazla