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All Journal Journal of Innovation and Applied Technology MNJ (Malang Neurology Journal) Universa Medicina Majalah Kesehatan FKUB Indonesian Journal of Medicine Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Respiratory Science Malang Respiratory Journal Indonesian Journal of Cancer International Journal of Radiology and Imaging Journal of Community Health and Preventive Medicine (JOCHAPM)
Dini Rachma Erawati
Department Of Radiology, Faculty Of Medicine, Universitas Brawijaya/Dr. Saiful Anwar General Hospital, Malang, Indonesia.
Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : respiratory science

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Correlation Between Changes in NLR Value and RECIST among Lung Cancer Patients at Saiful Anwar Malang Hospital Kristianto, Fransiskus; Setyawan, Ungky Agus; Erawati, Dini Rachma
Respiratory Science Vol. 5 No. 1 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i1.141

Abstract

Background: In practice, clinicians use Response Evaluation Criteria in Solid Tumors (RECIST) to decide the progressivity of lung tumors. Besides RECIST, there is an inflammatory marker called Neutrophil to Lymphocyte Ratio (NLR), which has prognostic value in cancer patients. Many previous studies have shown that NLR can predict the prognosis because inflammation in cancer patients is part of the tumor progressivity.  Therefore, the changes in NLR value have the potency to be one of the ways to decide the progressivity of tumors in lung cancer patients. Method: This cross-sectional study was conducted to see whether there is a correlation between RECIST and NLR in 95 lung cancer patients at Saiful Anwar Hospital whose data were taken from January 2022 to May 2023. The variable will be tested using the chi-square test to see the correlation and the logistic regression method to obtain the odds ratio. Results: There is a significant correlation between changes in NLR and RECIST with P=0.041.  Through Logistic Regression Analysis, the value of the odds ratio is 2.46 (CI 95%=1.03-5.94).  In the group with progressive RECIST, the average NLR value after therapy was higher than the average NLR value after therapy in the non-progressive group. Conclusion: This study concludes that changes in NLR value have the potency to help the determination process of lung cancer progressivity as RECIST does.
Co-Authors Adinda Amalia Dani Aditya Rahman, Perdana Aditya Sri Listyoko Aditya, Aldo Adolf Nggay, Andriana Agus Setyawan, Ungky Akbar, Jimmy Akbar Andri Andri Ari Irawan ARIFAH ARIFAH Astuti, Tri Wahyu Azmi, Mukhammad Binharyanto, Adlan Pratama Binharyanto Chozin, Iin Noor Chozin, Iin Nur Christian Surya Eka Putra Desfryda, Elynca Putri Djajalaksana, Susanthy Djanggan Sargowo Dwi Pratiwi, Suryanti Dwinadella, Sephia Eka Agustina, Dwi Rosa Elisabeth, Gracelia Elvira Sari Dewi Falyani, Silvy Amalia Gracelia Ruth Elisabeth Damanik Gregorio Satrio Pinunggul Handono Kalim hardiyanto, frenky Hendro Suryadi Hendy Setyo Yudhanto Hendy Setyo Yudhanto Hendy Setyo Yudhanto Hustorio Aliongko Simamora Iin Noor Chozin Imam Suseno Indah Sari, Fitri Isharanto, Artono Jane Sugiri, Yani Jani, Jane R Sugiri Jeffry Beta Tenggara Koernia Kusuma Wardhana Krisdiyanto, Peter Kristianto, Fransiskus Kristina Paskalita Kero Kusuma Wardhana, Koernia Kusworini Handono Listyoko, Aditya Sri Lyono, Albert Mahendra, Reza Aditya Maleachi, Reginald Mira Yuniarti Mohammad Faridza Setyo Hadikusumab Muhammad Zacky Hafiyyan Maulana Ngakan Putu Parsama Putra Noor Chozin, Iin Nurandhini, Marsha Nurdiana Nurdiana Nurima Diyah Oktavinayu Sari Latif Parsama Putra, Ngakan Putu Parsama, Ngakan Putu Putra Pratama, Mirza Zaka Pratiwi, Suryanti Dwi Pudjo, Herwindo Putri, Choirinnisa Meilia Ayu R. Sugiri, Yani Jane Rahayu Sartono, Teguh Rakhma , Sastia Rakhma, Sastia Retnani, Diah Prabawati Rezki Tantular Rezki Tantular Rini, Ni Made Rumaratu, Simon Petrus Hardiyanto santony, Santony Santoso, Agus Andreas Sari, Tita Luthfia Sastia Rakhma Semara Putra, Wayan Wahyu Setiadi, Satya Setiawan, Ungky Agus Setyawan, Ungky Agus Setyo Yudhanto, Hendy Sigiro, Rahel Margareth Febriana Soewondo, Widiastuti Sri Andarini Sugiri, Yani Jane R. Sugiri, Yani Jane Rosihaningsih Suryanti Dwi Pratiwi Susanthy Djajalaksana Susanthy Djajalaksana Susanti, Lia Sutedjo, Verawati Tantular, Rezki Tjakraatmadja, Ricardo Trimurtini, Asih Triwahju Astuti Ungky Agus Setyawan Wahono, Cesarius Singgih Wahyudy Prasetyo, Kevin Wantry, Kenty Wardhana, Koernia Kusuma Wardhana, Kurnia Winarni, Tika Wahyu Wisnu Barlianto Yani Jane R. Sugiri Yani Jane Sugiri Yudhanto, Hendi Setyo Yudhanto, Hendy Setyo Yusdianto, Adrian Yuyun Yueniwati Zaenal Kusuma