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All Journal Aptisi Transactions on Technopreneurship (ATT) Jurnal Abdi Insani Archives Pharmacia
Reinaldo Pradana
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Social Sciences

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EVALUASI PENGETAHUAN FAKTOR RESIKO DIABETES DAN DAMPAKNYA TERHADAP KADAR GULA DARAH SEWAKTU PADA MASYARAKAT KEMBANGAN UTARA, JAKARTA BARAT Nadiya Nurul Afifah; Reinaldo Pradana; Melisa Resmiati; Lanny Indah Permatasari
Jurnal Abdi Insani Vol 11 No 3 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i3.1917

Abstract

Diabetes Mellitus (DM) is a chronic, non-communicable metabolic disease with increasing prevalence and morbidity rates. There has been a 2% increase in DM prevalence among the population aged 15 years and older, with the highest prevalence found in DKI Jakarta (2.3%). Patients' understanding or knowledge of DM and its risk factors is closely related to the incidence of type II DM. The influence of education on public knowledge and the incidence of type II DM has also been widely demonstrated. This study was conducted to map the profile of Random Blood Glucose (RBG) levels and the knowledge of the residents of Kelurahan Kembangan Utara, West Jakarta, regarding the risk factors for type II DM and preventive measures. Methods: Community education was carried out through a mini-seminar on type II DM risk factors and prevention, followed by a questionnaire to assess knowledge, RBG testing, and consultation on the interpretation of the results, as well as the distribution of educational pamphlets as visual aids. Results and Conclusion: Respondents' knowledge about good nutrition as a preventive measure for type II DM was found to be lacking. However, their knowledge of type II DM risk factors and RBG levels was considered fairly good (75 and 112 mg/dL). The study also showed no significant differences in RBG levels among respondents with questionnaire scores of 60, 80, and 100 (p≥0.05), although the median RBG level in the 60-score group was the highest. Clinically, this could be interpreted to suggest that respondents with the lowest scores had the highest RBG levels.
Formulasi dan Uji Stabilitas Fisik Sediaan Masker Clay Ekstrak Daun Kapuk Randu (Ceiba pentandra(l.)Gaertn) Pradana, Reinaldo; Mahfud, Ahmad; Pertiwi, Ratih Dyah; Ghozaly, Muchammad Reza
Archives Pharmacia Vol 7, No 1 (2025): ARCHIVES PHARMACIA
Publisher : Lembaga Penerbitan Universitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/ap.v7i1.9114

Abstract

Penggunaan kosmetik saat ini bukan hanya untuk meningkatkan estetika saja tetapi juga untuk menjaga kesehatan kulit. Masker clay adalah salah satu kosmetik yang memiliki sifat pembersihan dan pengontrol minyaknya serta dapat dikombinasikan dengan bahan antibakteri. Penelitian ini bertujuan untuk memformulasikan masker clay yang mengandung ekstrak daun Kapuk Randu (Ceiba pentandra (L) Gaertn.) dan mengevaluasi stabilitas fisiknya. Masker clay diformulasikan dengan ekstrak etanol daun Kapuk Randu  pada konsentrasi yang berbeda mulai dari 3%, 6%, dan 9%, serta eksipien seperti bentonit, kaolin, xanthan gum, gliserin, titanium dioksida, nipagin, dan natrium lauril sulfat. Karakterisasi masker clay dinilai melalui pengujian organoleptik, pengukuran viskositas, pengujian pH, pengujian homogenitas, pengujian daya sebar, evaluasi waktu pengeringan, dan pengujian stabilitas (uji cycling). Hasil penelitian menunjukkan bahwa ekstrak daun Kapuk Randu pada konsentrasi 3%, 6%, dan 9% dapat berhasil diformulasikan menjadi masker clay. Uji stabilitas fisik menunjukkan bahwa formulasi masker clay menunjukkan stabilitas yang baik. Tidak ada perubahan signifikan dalam hal sifat organoleptik, pH, homogenitas, waktu pengeringan, daya sebar, dan viskositas
Gold Nanoparticle Synthesis Using Quercetin: Innovation in Biopreneur Pertiwi, Ratih Dyah; Fitria, Pika Ayu; Utami, Tyas Putri; Pamungkas, Rian Adi; Pradana, Reinaldo; Chamroonsawasdi, Kanittha
Aptisi Transactions On Technopreneurship (ATT) Vol 7 No 1 (2025): March
Publisher : Pandawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34306/att.v7i1.405

Abstract

Biosynthesis offers an environmentally friendly approach for manufacturing nanoparticles, with flavonoids such as quercetin showing potential as reducing agents. This study aimed to synthesize gold nanoparticles (AuNPs) from HAuCl4 using quercetin as a reducing agent. The synthesis process was monitored using UV-Vis spectrophotometry, and the particle size and stability of the nanoparticles were characterized using a Particle Size Analyzer (PSA). The synthesized AuNPs exhibited a color change from light yellow to deep purple, with a peak absorbance between 500 600 nm. The average particle size was found to be 116.7 nm, with a zeta potential of -12.2 mV, and a polydispersity index of 0.293. The inhibitory activity of the AuNPs was assessed by their effect on the tyrosinase enzyme, yielding an IC50 value of 970 μg/mL. These results suggest that gold nanoparticles synthesized using quercetin are stable and exhibit potential inhibitory activity against tyrosinase. The study concludes that this green synthesis method has the potential for further development in drug delivery systems, providing an innovative approach in biopreneurship.
Co-Authors Chamroonsawasdi, Kanittha Fitria, Pika Ayu Ghozaly, Muchammad Reza Lanny Indah Permatasari, Lanny Indah Mahfud, Ahmad Melisa Resmiati Nadiya Nurul Afifah Pertiwi, Ratih Dyah Rian Adi Pamungkas Tyas Putri Utami