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Journal : Journal of Science Innovare

Activity of Antioxidant and Inhibitor α-Glucosidase Instant Granul Ethanol Tea Leaf Extract (Camellia sinensis) and Tea Benalu (Scurulla atropurpureea BL Dans) Setiani, Lusi Agus; Sari, Bina Lohita
Journal of Science Innovare Vol 1, No 01 (2018): Journal of Science Innovare
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (490.824 KB) | DOI: 10.33751/jsi.v1i01.676

Abstract

Tea leaves are plants that are widely spread especially in the area of West Java, while parasites are parasitic plants in tea trees that empirically have various properties such as antioxidants and anti diabetic. The α-glucosidase inhibitor is one of the therapeutic drugs for diabetic that works by inhibiting carbohydrate metabolism. Instant granule preparation is one form of dosage used by dissolving in water. This study aims to determine the antioxidant activity and inhibitors of instant granular α-glucosidase ethanolic extract of Tea and Tea Tea leaves. The extract was obtained from extraction with 60% ethanol solvent-assisted extraction (MAE) method. Research was done by making 3 formula (Formula 1, 2 and 3) with comparison of tea leaf extract, parasite, Polivinil pyrrolidone (PVP) and cyclodextrin ie 26,88%, 1,8%, 2%, 0% (Formula 1) 26.88%, 0%, 3%, 12% and 0% (Formula 2), 1.8%, 4%, 15% (Formula 3). Formula 2 is active as an antioxidant and α-glucosidase enzyme inhibitor with IC50 values of 68.21 and 56.76 ppm. Keywords: Tea Leaves, Benalu Tea, Antioxidants, α-glucosidase Inhibitors, Instant Granules
Effectiveness Of Tajin Water (Rice-Water) As A Coupling Food To Improve Weight Board (Mus Musculus) Lusi Agus Setiani; Moerfiah Moerfiah; Putri Kemala Dewi
Journal of Science Innovare Vol 6, No 1 (2023): Journal of Science Innovare, Volume 06 Number 01 2023
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jsi.v6i1.7747

Abstract

Malnutrition can occur on children of aged 6 to 24 months. During this period, there is generally a change in needs from exclusive breastfeeding to complementary foods and additional food can also be added. Starch water which is a springy white liquid obtained from rice that is cooked with the nutritional content of energy, protein, fat, carbohydrates, calcium, iron, vitamin B1. This study aims to test the effectiveness, determine the best concentration and determine the influence of the length time from using of starch water as an additional complementary food to increase body weight of male mice (Mus musculus) for 21 days by oral treatment. The experiment and method that used in this experiment is was pretest-posttest control group design. Starch water is obtained by means of rice being heated with 1200 mL of water for ± 30 minutes, filtering and extracting is obtained. Starch water concentrations commonly used empirically tested in this study are concentrations of 12.5%; 18.7%; 25%. The 25% concentration is the concentration that has an effective effect on body weight of mice with the results (21.87 ± 4.29) which differ 2.38% from the positive control results (24.25 ± 8.93).