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Journal : Journal of Nursing and Health (JNH) Akper Yakpermas Banyumas

KORELASI ANTARA TIMBAL DALAM DARAH DAN ESTIMASI LAJU FILTRASI GLOMERULUS DI INDUSTRI PERCETAKAN Wimpy Wimpy
Journal of Nursing and Health Vol. 9 No. 3 (2024): Journal of Nursing and Health
Publisher : Yakpermas Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52488/jnh.v9i3.383

Abstract

Percetakan menghasilkan limbah bahan berbahaya beracun berupa sisa tinta pewarna yang mengandung timbal. Pekerja percetakan dapat berisiko terpapar timbal melalui jalur pernafasan, oral maupun dermal. Timbal yang terakumulasi dalam tubuh manusia dapat menimbulkan risiko gangguan kesehatan seperti kerusakan ginjal. Salah satu parameter untuk menilai fungsi ginjal yang mengalami kerusakan adalah dengan mengamati estimasi laju filtrasi glomerulus. Tujuan dari penelitian ini adalah untuk mengetahui kadar timbal darah dan estimasi laju filtrasi glomerulus pada pekerja percetakan serta hubungan kedua variabel tersebut.  Penelitian ini dilakukan dengan menggunakan pendekatan observasional analitik dengan desain cross sectional. Sebanyak 20 sampel darah pekerja percetakan diambil dengan teknik kuota sampling. Spektrofotometer serapan atom digunakan untuk menganalisis konsentrasi timbal darah sedangkan hasil estimasi laju filtrasi glomerulus didapatkan dengan menghitung kadar kreatinin yang diperiksa menggunakan fotometer kemudian dianalisis menggunakan rumus Cockcroft-Gault. Sebanyak 100 % responden memiliki kadar timbal yang melebihi ambang batas yang ditetapkan  oleh centers for disease control and prevention yaitu melebihi 3,5 µg/dL. Didapatkan 10 %  responden yang mengalami penurunan estimasi laju filtrasi glomerulus. Setelah dilakukan uji korelasi spearman’s rho diperoleh nilai signifikansi sebesar 0,613 (P>0,05) sehingga disimpulkan tidak terdapat hubungan yang signifikan antara kadar timbal darah dengan estimasi laju filtrasi glomerulus pekerja industri percetakan.
PERBEDAAN KADAR ZAT BESI SERUM BERDASARKAN STATUS KADAR TIMBAL DARAH PADA PEROKOK AKTIF Wimpy, Wimpy; Dwi Utami, Hesti
Journal of Nursing and Health Vol. 10 No. 2 (2025): Journal of Nursing and Health
Publisher : Yakpermas Press

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Abstract

Exposure to lead (Pb) from cigarette smoke can interfere with iron (Fe) metabolism in the human body. Inhaled lead enters the bloodstream through the lungs and binds to erythrocytes, potentially affecting the absorption and distribution of iron. Active smokers are at risk of accumulating heavy metals such as lead, which over time may disrupt the balance of essential micronutrients, including iron. This study aims to analyze the difference in serum iron levels based on blood lead status among active smokers. This research used an analytical observational approach with a cross-sectional design. A total of 20 active smokers were selected using purposive sampling. Blood lead levels were measured using Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES), while serum iron levels were analyzed using the photometric method on a Cobas C111 device. The results showed that 35% of respondents had blood lead levels exceeding the CDC (Centers for Disease Control and Prevention) threshold of >3,5 µg/dL. Additionally, 15% of respondents had serum iron levels below the normal range, and 10% had levels above the normal reference according to the World Health Organization (WHO). The Independent Samples T-Test revealed a p-value of 0,975 (p > 0,05), indicating no significant difference in serum iron levels between groups with normal and elevated blood lead levels. The mean difference in serum iron between groups was only 0,42 µg/dL, with a 95% confidence interval that was wide and included zero.
ANALISIS KADAR RETIKULOSIT BERDASARKAN KATEGORI KADAR TIMBAL DARAH PADA PEROKOK AKTIF Safira, lLaurentia Filda; Wimpy, Wimpy
Journal of Nursing and Health Vol. 10 No. 2 (2025): Journal of Nursing and Health
Publisher : Yakpermas Press

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Abstract