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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
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Articles 407 Documents
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Neurological Abnormalities in Congenital Rubella Syndrome and Possible Pathophysiology Erny, Erny; Prasetyo, Okky; Soekanto, Ayli
Indonesian Journal of Medicine Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.4.585

Abstract

Background: Congenital rubella syndrome is a disease that is a relative severe health problem because it causes multiorgan disability. The purpose of the study was to describe the neurological abnormallities that occur in congenital rubella syndrome and its pathophysiology.Case Presentation: A descriptive study with the subjects of the study of infants and children with congenital rubella syndrome found in the private practice of pediatricians for 10 years aged 15 years with the most complaints of developmental and growth delays, recurrent seizures and behavioral disorders. most are first children with mothers without Measles, Mumps, and Rubella (MMR) vaccination. Inclusion criteria: infants and children with clinical manifestations of at least 2 of all major clinical signs (hearing loss, congenital cataracts and congenital heart defects) accompanied by evidence of infection in the form of rubellaspecific serum IgM and a history of the mother experiencing infection during pregnancy as evidenced by IgG results and or IgM rubella antibodies.Results: 13 cases were obtained, 92.3% of the case population with multiorgan disability and only 1 case (7.69%) with neurological disorders alone. 84.6% of cases of neurological disability occurred as a result of infection in the 1st trimester.Conclusion: Neurological abnormalities were acquired in the entire study population and were mostly due to infections in the 1st trimester of pregnancy.Keywords: neurological abnormalities, congenital rubella syndrome.Correspondence: Erny. Pediatric Department Medical Faculty Wijayakusuma University. Jl. Dukuh Kupang XXV no 54 Surabaya, East Java, Indonesia. Email: drernyspa@gmail.com. Mobile: 0818381740.Indonesian Journal of Medicine (2022), 07(04): 449-455https://doi.org/10.26911/theijmed.2022.07.04.10
Meta-Analysis the Effect of Chlorhexidine and Povidone Iodine Mouthwashes on Viral Load SARS-CoV-2-Saliva Narulita, Danti; Rahardjo, Setyo Sri; Murti, Bhisma
Indonesian Journal of Medicine Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.4.589

Abstract

Background: The strategy to reduce the risk of transmission of COVID-19 is to reduce the salivary SARS-CoV-2 viral load. Chlorhexidine and povidone iodine mouthwash are common active ingredients in oral antiseptics that have efficient viral activity against salivary SARS-CoV-2. This study aims to combine the results of several effect sizes regarding the effect of using chlorhexidine and povidone iodine mouthwash on the salivary SARS-CoV-2 viral load from various countries.Subject and Method: This study is a meta-analysis with the following PICO model, P: COVID-19 patients. I: use of chlorhexidine and povidone iodine mouthwash. C: no mouthwash. O: salivary SARS-CoV-2 viral load. A search for the articles used in this study was carried out using the keywords “COVID-19” OR “SARS-CoV-2” OR “viral load” OR “SARS-Cov-2 viral load” OR “Chlorhexidine mouthrinse” OR “Povidone Iodine mouthrinse ” OR “Randomized Controlled Trial” OR “RCT” between 2012-2022 from the PubMed, Springerlink, Elsevier, Google Scholar and Wiley Online Library databases. The inclusion criteria used in this study were full-text articles using a Randomized Controlled Trial (RCT) design. The analysis used was multivariate with Standardized Mean Difference (SMD). The articles collected were then critically reviewed using the PRISMA checklist, then the data were analyzed using the Review Manager 5.4 tool.Results: This meta-analysis examined 10 articles with a Randomized Controlled Trial (RCT) study design originating from Singapore, Saudi Arabia, Iran, Brazil, Italy, South Korea and Malaysia. A meta-analysis of 7 articles showed that the use of chlorhexidine mouthwash could reduce salivary SARS-CoV-2 viral load by 0.12 units lower than without the use of mouthwash (SMD= -0.12; 95% CI= -0.33 to 0.09; p=0.250). Meanwhile, 7 articles showed that the use of povidone iodine mouthwash could reduce the salivary SARS-CoV-2 viral load by 0.64 units lower than without the use of mouthwash (SMD= -0.64; 95% CI= -1.51 to 0.23; p=0.150).Conclusion: The use of chlorhexidine and povidone iodine mouthwashes can reduce the amount of salivary SARS-CoV-2 viral Keywords: mouthwash, chlorhexidine, povidone iodine, COVID-19, salivary SARS-CoV-2 viral load.Correspondence: Danti Narulita. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah. Email: dantinarulita@yahoo.co.id. Mobile: +6282158818400.Indonesian Journal of Medicine (2022), 07(04): 387-400https://doi.org/10.26911/theijmed.2022.07.04.04
Convalescent Plasma Treatment for Moderate to Critical Ill COVID-19 Patients – A Safe but Futile Treatment: A Non-Randomized Comparative Study Aphridasari, Jatu; Soetjahjo, Bintang; Joko, Agus; Sidharta, Rina; Harsini, Harsini; Arifin, Arifin; Permana, Septian Adi; Saraswati, Kunti; Adhiputri, Artrien; Marwanta, Sri; Laqif, Abdurahman; Danuaji, Rivan
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.620

Abstract

Background: In a number of cases of viral infection, convalescent plasma therapy has been effective. Reportedly, the use of convalescent plasma as a therapy for COVID-19 patients with severe and life-threatening disorders is beneficial at this time. This study aims to assess the effectiveness and safety of convalescent plasma transfusions in hospitalized COVID-19 patients. Subjects and Method: This was a clinical trial employing a non-randomized comparative study. A historical control group (21 samples) and convalescent plasma transfusions (21 samples) was selected consecutively from hospitalized COVID-19 patients between May 6th, 2020, and May 6th, 2021 at Dr. Moewardi General Hospital. We assessed and quantified viral clearance in the laboratory. Statistical analysis is performed in SPSS version 20.0. Results: Plasma was taken from fifteen convalescent donors. In the plasma convalescent treatment group, there was a statistically significant difference between outcome and severity degree (p = 0.005). In addition, there was a substantial discrepancy between the result group and the control group (p 0.005). Significant differences in post-treatment NLR between the control and treatment groups (p 0.005). In addition, there were statistically significant differences between the control and treatment groups in post-treatment hsCRP levels (p 0.005). In addition, there were statistically significant differences (p 0.005) between all groups' inflammatory markers and outcomes. Conclusion: Using convalescent plasma to treat patients with COVID-19 is a rather safe practice. Our analysis demonstrated that the administration of convalescent plasma did not enhance survival or clinical outcomes for COVID-19 patients with moderate to severe disease. Keywords: COVID-19, convalescent therapy, critical ill
Re-Infection of COVID-19 at Dr. Moewardi General Hospital, Surakarta, from March 2020 to June 2021 Aphridasari, Jatu
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.621

Abstract

Background: COVID-19 reinfection has been identified and is being studied. Several risk factors, including being a health worker and having A blood type, are linked to reinfection, and comorbidities such as hypertension, obesity, diabetes, and asthma influence the disease's severity. To identify mutational variations associated with viral virulence and spread, genetic studies are required. The purpose of this study is to determine the prevalence of SARS-CoV-2 reinfection, as well as patient characteristics and risk factors related to SARS-CoV-2 reinfection. Subjects and Method: This is a retrospective cohort study using data from the medical records of patients with COVID-19 reinfection treated at the Dr. Moewardi General Hospital (RSDM) Surakarta from March 2020 to June 2021. A sample was collected from 19 men and 20 women. The degree of COVID-19 infection is the dependent variable. Gender, occupation, comorbidities, and immunization history were the independent variables. The entire sampling method was employed in this investiga¬tion (consecutive sampling). Data is handled in Microsoft Excel 2010, and statistical analysis is performed in SPSS version 20.0. Results: COVID-19 re-infection is equally likely in men and women. The average patient age was 42 years, with patients ranging in age from 25 to 73 years. Patients in the study were classified as either health workers or non-health workers, with 29 (76.3%) and 9 (23.7%) respectively. Due of restricted resources, the average period of COVID-19 re-infection is 197.6 +/- 97 days without genomic sequence investigation. Comorbidities were discovered in 11 of 38 COVID-19 reinfection patients (29%) Only 6 individuals (15.8%) with COVID-19 reinfection had a history of vaccination. Conclusion: Using convalescent plasma to treat patients with COVID-19 is a rather safe practice. Our analysis demonstrated that the administration of convalescent plasma did not enhance survival or clinical outcomes for COVID-19 patients with moderate to severe disease. Keywords: COVID-19, COVID-19 reinfection, health workers, comorbidity Correspondence: Jatu Aphridasari. Department of Pulmonology and Respiratory Medicine, Dr. Moewardi General Hospital, Surakarta – Indonesia. jatuparu@staff.uns.ac.id. Mobile: +6281289991329.
Difference in the Effect of Giving Neck Stabilization Exercise with Stretching on Improvement of Neck Functional Ability in Non-Specific Neck Pain Dekamelania, Almas Khonsa; Basuki, Nur; Wahyono, Yulianto
Indonesian Journal of Medicine Vol. 8 No. 3 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.3.631

Abstract

Background:  Tailor workers when working with a bowed position and a long static position, the muscles will contract excessively resulting in spasms and pain that causes non-specific neck pain which will interfere with the functional ability of the neck. Neck stabilization exercises and stretching can be exercises to improve neck functional ability in non-specific neck pain. This study aims to determine the difference in the effect of neck stabilization exercise and stretching on increasing the functional ability of the neck in non-specific neck pain. Subjects and Method:  This study is a randomized controlled trial using a two-group pretest and post-test design conducted at sevinta convection and padi emas from November to December 2023. A total of 24 subjects were selected by random sampling and randomly allocated into 2 groups. Group 1 was given neck stabilization exercise and group 2 was given stretching. The dependent variable is neck functional ability in non-specific neck pain and the independent variables are neck stabilization exercise and stretching. The measuring instrument used is the neck disability index to measure neck functional ability. Data analysis using independent sample t-test. Results:  The results after the intervention obtained neck functional ability in non-specific neck pain increased in both groups. There is a statistically significant difference in neck stabilization exercise (Mean = 4.00; SD = 2.21) and stretching (Mean = 6.83; SD = 2.79), and it was statistically significant (p = 0.012). Conclusion:  There is a significant difference in the effect of neck stabilization exercise and stretching on improving neck functional ability in non-specific neck pain. Neck stabilization exercise is more influential than stretching on improving neck functional ability in non-specific neck pain. Keywords:  neck stabilization exercise, stretching, neck disability index. Correspondence:  Yulianto Wahyono, School of Health Polytechnics Ministry of Health Surakarta. Jl. Adi Sumarmo, Tohudan, Colomadu, Karanganyar 57173, Central Java, Indonesia. Email: yulianto2wahyono@gmail.com. Mobile: 085742017903. Indonesian Journal of Medicine (2023), 08(03): 258-265
Massive Mature Mediastinal Teratoma With Malignant Transformation: An Unusual Case Report Kalua, Karla; Soewondo, Widiastuti
Indonesian Journal of Medicine Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.2.643

Abstract

Background: Teratoma is a type of germ cell tumor that is rarely found in the anterior mediastinum. Meanwhile, mature mediastinal teratoma with malignant transformation is rare and develops rapidly, with a poor prognosis. This article aims to report one of the uncommon cases of mature teratoma and discuss its imaging features thereby adding insight in providing an accurate diagnosis of this condition. Case Report: This study presents a case of a 26-year-old male patient who has complained of shortness of breath for 3 months and worsening in the last 3 days. The patient passed through a chest radiographic examination and was diagnosed with a mediastinal tumor. The contrast-enhanced chest computed tomography showed a huge mediastinal mass occupying the right and left hemithorax, measuring 16.9 cm x 20.5 cm x 20.9 cm and pressing against the chest wall, esophagus, trachea, great vessels, and the vital organs, lungs as well as heart, causing several complications in patients. Conclusion: Knowledge of the teratoma radiological appearance and the characteristics of the various subtypes is very important in the diagnosis of mediastinal teratoma diagnosis for immediate and appropriate treatment.
Meta-Analysis the Effectiveness of Speech Therapy on Phonation Improvement in People Diagnosed with Parkinsons Disease Putri, Anitasari Kartika; Prasetya, Hanung; Murti, Bhisma
Indonesian Journal of Medicine Vol. 8 No. 3 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.3.651

Abstract

Background:  Parkinson's disease (PD) is a complex, progressive neurodegenerative disease characterized by tremor, rigidity, slow movement, and postural instability. Phonation disturbances are the most frequently observed speech characteristics in PD patients. The purpose of this study was to estimate the effectiveness of speech therapy interventions for phonation improvement in people with a diagnosis of Parkinson's disease.Subjects and Method:  This study is a meta-analysis of a number of Randomized Controlled Trial study designs. The articles used in this study were obtained from several databases including PubMed, Google Scholar, and Springer Link. The article search was carried out by considering the eligibility criteria defined using the PICO model. The population in the study were people with a diagnosis of Parkinson's disease with intervention in the form of speech therapy intervention, comparison, namely no speech therapy intervention, outcome in the form of phonation. The keywords to search for articles are as follows: “Intervention Speech Therapy” OR “Speech Therapy” OR “Phonation” OR “Voice” OR “Parkinson's Disease” AND “Randomized Controlled Trial” OR “RCT”. The articles included in this study are full-text articles with a Randomized Controlled Trial (RCT) study design. Articles are collected using PRISMA flow diagrams. Articles were analyzed using the Review Manager 5.3 application.Results:  A total of 7 articles were reviewed in this study from the United States, North America, and Austria. The total sample size in this study was 213 subjects. A meta-analysis showed that speech therapy was effective for improving phonation in people with a diagnosis of Parkinson's disease (SMD = 2.52; 95% CI = 1.79 to 3.24; p<0.001).Conclusion:  Speech therapy is effective for improving phonation in people with a diagnosis of Parkinson's disease.Keywords:  speech therapy, phonation, voice, parkinson disease.Correspondence: Anitasari Kartika Putri. Masters Program in Public Health. Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: anitaaakartika@gmail.com Mobile: 0857-2777-7217Indonesian Journal of Medicine (2023), 08(03): 277-285https://doi.org/10.26911/theijmed.2023.08.03.05
Anterior Cruciate Ligament Ruptured Concomitant Meniscus Discoid in Young Patient: A Rare Case Report Aryana, I Gusti Ngurah Wien; Trisaputra, I Ketut Wahyu; Febyan, Febyan
Indonesian Journal of Medicine Vol. 8 No. 3 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.3.654

Abstract

Background:  Abnormalities of the human meniscus, including discoid meniscus, double-layered meniscus, and ring-shaped meniscus, have been reported. The prevalence of discoid meniscus is extremely rare, with an incidence of 0.9%－2.4% in the Asian population. Traditionally, discoid meniscus concomitant anterior cruciate ligament (ACL) ruptures are extremely rare cases. The aim of this study is to discuss a rare case to provide diagnosis and management properly by using arthroscopy.Case Presentation:  A 21-year-old male Balinese, complained of pain in his right knee after fast walking for two months and an unstable knee in the past 1 year ago. On physical examination, the range of motion was limited due to the pain for flexion of more than 90°. Special tests such as Lachman test positive, and Anterior drawer test positive. The patient had medial joint line tenderness, and a McMurray test elicited pain on the medial joint line. Meanwhile, an MRI examination of the right knee showed a discoid medial meniscus with a horizontal cleavage tear and a discoid lateral meniscus with an incomplete tear. We performed a partial meniscectomy of the incomplete discoid medial meniscus and resection of the pathologic medial patellar plica. We performed surgical reconstruction of the ACL ruptured after the meniscus was repaired.Results:  We presented a 21-year-old male with discoid meniscus concomitant ACL rupture to his right knee. After the patient was performed with partial meniscectomy of the incomplete discoid medial meniscus and resection of pathologic medial patellar plica following surgical reconstruction of the ACL ruptured. The patient had no limitation of motion or pain 1 year after the operation and he had no complaints and was satisfied with the result by radiograph.Conclusion:  We concluded that This rare case of medial discoid meniscus concomitant with the ACL rupture must be reconstructed. The treatment of discoid meniscus should consider its tear pattern and whether it is symptomatic. With the development of arthroscopic techniques, the treatment of discoid meniscus has gradually changed from total meniscectomy or partial meniscectomy.Keywords:  anterior cruciate ligament, meniscus, discoid, knee, arthroscopy.Correspondence:  I Gusti Ngurah Wien Aryana. Department of Orthopaedic & Traumatology, General Central Hospital of I.G.N.G Ngoerah Central Hospital/ Faculty of Medicine, Udayana University, Bali, Indonesia. Email: wienaryanaortho@gmail.com. Mobile: +62811-385-263.Indonesian Journal of Medicine (2023), 08(03): 317-324https://doi.org/10.26911/theijmed.2023.08.03.09
Physiotherapy Rehabilitation for Accelerating the Recovery of Patient with Anterior Cruciate Ligament Total Reconstruction and Meniscal Repair: A Case Report Saputra, Suryo; Kasumbung, Muhammad Tasa; Larasati, Prihantoro; Setianing, Retno
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.657

Abstract

Background: The Anterior Cruciate Ligament (ACL) is a ligament that functions to limit the movement of the tibia toward the anterior and excessive rotation, while the meniscus serves as shock absorption, load transmission, and the stabilizer of the knee joint. About 22% to 86% meniscal tear incidences occurring along with ACL injuries is. The study aims to determine the role of physiotherapists in the postoperative rehabilitation process of patients of ACL Reconstruction (ACLR) and meniscal repair in preventing postoperative complications and functional abilities of patients. Case Report: The patient was a 35-year-old adult male who suffered a complete tear in the ACL and meniscus of the left knee. The patient underwent ACLR and meniscal repair with arthroscopic surgery 2 years after injury with Bone-Pattelar tendon-bone autograph. 2 weeks post-surgery the patient visited the physiotherapy polyclinic with medical conditions of difficulty in bending and straightening the knee, still feeling pain and thick in the knee area. Results: The physiotherapist program was conducted three times and it was a home program-based exercise. The physiotherapist program and outcomes used in the first phase focused on exercises to improve ROM (Goniometer), oedema management (Medline), pain reduction (Numerical Rating Scale), activation exercises, and surrounding muscle strength (Sphygmomanometer), and improve functional ability (Tegner Lysholm Knee Scale) as well as the provision of home programs Performed by regular monitoring of exercise intensity using isometric, isotonic, and isokinetic exercises, which were given according to the concept of progressive loading. Conclusion: This case study shows that surgery combined with a comprehensive physiotherapy program plan in ACLR and meniscal repair cases, as well as adding home-based exercise programs with intense monitoring, generate more effective results. Keywords: physiotherapy rehabilitation, anterior cruciate ligament total, meniscal repair Correspondence: Suryo Saputra Perdana. Physiotherapist Profession Education Department, Faculty of Health Sciences, Universitas Muhammadiyah Surakarta, Sukoharjo, Central Java, Indonesia. Email: suryo.saputra@ums.ac.id. Mobile: +6281298563988.
Effectiveness of Indoor Residual Spraying as A Method of Controlling Dengue Fever in Communities: A systematic review Anggraeni, Titik; Sarwoko, Sarwoko; Sutanta, Sutanta; Saputro, Bambang Sudono Dwi; Ulfah, Hana Rosiana; Hasbi, Habid Al; Afifah, Vina Asna; Sari, Ilma Widiya; Kurniawati, Emy; Bahri, Ahmad Syamsul; Herbasuki, Herbasuki
Indonesian Journal of Medicine Vol. 8 No. 3 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.3.659

Abstract

Background: Dengue remains a significant public health issue in the Western Pacific Region. In the absence of a vaccine, vector control is the mainstay for dengue prevention and control. This study aimed to explore the effectiveness of Indoor Residual Spraying as A Method of Controlling Dengue Fever in Communities. Subjects and Method: A systematic review was conducted by searching articles from PubMed, ResearchGate, Science Direct, Google Scholar, and EBSCO is an article published from 2013 to 2023. The keywords were “dengue hemorrhagic fever” OR “DHF” AND “community” OR “family” AND “disaster” AND “IRS” OR “indoor residual spraying”. The inclusion criteria were a Cross-sectional study. The articles were selected by PRISMA flow diagram method. Results: A total of 9 studies were included in this review. All of the studies stated that IRS can have both an immediate and sustained effect on reducing adult and immature A. aegypti populations and should be considered as an adult mosquito control strategy by dengue vector control programs also IRS led to 86-96% reduction in dengue cases in sprayed premises, compared to unsprayed controls. Conclusion: IRS significantly reduces the malaria burden in high-transmission settings. Keywords: dengue hemorrhagic fever, DHF, family, community. Correspondence: Titik Anggraeni. School of Health Sciences Estu Utomo Boyolali, Central Java, Indonesia. Jl. Tentara Pelajar 7, Mudal, Boyolali, Central Java, Indonesia. Email: titik.anggraeni146@gmail.com. Mobile: +62 858-6729-2673.  

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