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INDONESIA
Jurnal Kartika Kimia
Published by Universitas Jenderal Achmad Yani
ISSN : 26551322     EISSN : 26550938     DOI : -
Core Subject : Science, Education, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education
Jurnal Kartika Kimia is National Journal that publish all research article/ review/ short communication related to progres of chemistry researchs. Scope of this journal are: 1) Analytical Chemistry ; 2) Inorganic Chemistry ; 3) Physical Chemistry ; 4) Organic Chemistry ; 5) Biochemistry also applied chemistry such as Material Chemistry, Environmental Chemistry, Catalyst, Food Chemistry, Natural Products Chemistry, and Computational Chemistry. Jurnal Kartika Kimia published by Department of Chemistry, Faculty of Sciences and Informatics, Jenderal Achmad Yani University. Jurnal Kartika Kimia publish 2 issues per year at May and November. Jurnal Kartika Kimia can be accessed via print (ISSN 2655-1322) and online (ISSN 2655-0938)
Arjuna Subject : -
Articles 162 Documents
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Antibacterial Activity of the Endophytic Fungus Fusarium solani Isolated from the Stem of Bauhinia fulva Blume Against Staphylococcus aureus and Escherichia coli Sari Purbaya; Yenny Febriani Yun; Dara Santika; Yosephine Liliana Intan Danar Saputri; Fitria Rahma Dewi; Riana Zevanisa Arsyi; Dayu Yunita; Fahriani Istiqomah; Siska Elisahbet Sinaga
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1087

Abstract

Endophytic fungi are microorganisms that live within plant tissues and are capable of producing secondary metabolites with potential antibacterial, antifungal, and anticancer activities. This study aimed to isolate, identify, and evaluate the antibacterial activity of endophytic fungi from the stem of Bauhinia fulva Blume through isolation, morphological identification, fermentation, ethyl acetate extraction, phytochemical screening, and antibacterial testing using the disk diffusion method. The results showed that the isolated endophytic fungus was identified as Fusarium solani, producing 1.4095 g of ethyl acetate extract. Phytochemical screening revealed the presence of alkaloids, flavonoids, quinones, and triterpenoids/steroids. The ethyl acetate extract of F. solani exhibited antibacterial activity against Staphylococcus aureus with a maximum inhibition zone of 20.85 mm and lower activity against Escherichia coli with a maximum inhibition zone of 5.56 mm, indicating its potential as a natural source of antibacterial compounds.
Sustainable Green Synthesis of ZnO Photocatalysts Using Shallot Peel Extract as Capping Agent for Efficient Photodegradation of Rhodamine B Didi Prasetyo Benu; Cindy Claudia Christanti; I Gede Arya Wiguna; Fry Voni Steky; Veinardi Suendo
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1103

Abstract

Green synthesis strategies offer a sustainable approach for preparing semiconductor photocatalysts with tunable properties. In this study, ZnO particles were synthesized using shallot peel extract, and their structural, morphological, optical, and photocatalytic properties were systematically investigated. Structural characterization by Raman spectroscopy and X-ray diffraction confirmed the formation of phase-pure wurtzite ZnO, with crystallite sizes in the nanometer range. Scanning electron microscopy revealed hexagonal rod-like morphologies with dimensions of 1–2 μm, which are interpreted as polycrystalline assemblies of aggregated nanocrystallites. Optical analysis using UV–Vis diffuse reflectance spectroscopy showed a direct bandgap of 3.02 eV and additional visible-light absorption, which may be associated with defect states and possible extrinsic contributions. Photoluminescence spectroscopy exhibited green emission attributed to intrinsic defects. The photocatalytic performance of the synthesized ZnO was evaluated through the removal of Rhodamine B under irradiation, achieving a maximum removal efficiency of 97.68% within 150 min. Kinetic analysis indicated that the process follows a pseudo-first-order model with an apparent rate constant of 0.0290 min⁻¹. The observed photocatalytic performance may be associated with the structural and optical characteristics of the synthesized ZnO. However, the specific roles of these factors, as well as the contribution of adsorption, cannot be conclusively distinguished in the absence of a control sample. Overall, this study provides insight into the relationship between synthesis conditions and the resulting properties of green-synthesized ZnO, while highlighting the need for further investigation to clarify the underlying mechanisms. This work demonstrates that shallot peel extract is an effective and environmentally benign capping agent for engineering ZnO photocatalysts with high efficiency for wastewater treatment applications.
Electrodeposition of Zinc on Iron Plates in the Presence of N,N-Dimethylurea and Sapindus rarak Rind Extract as Additives Sal Prima Yudha S; Akhmad Ues; Agus M.H. Putranto; Muhamad Alvin Reagen; Muhammad Adli Afif; Jimmy Askhan; Lenon Jus Pentus Tarigan
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1114

Abstract

A study on the addition of natural in the form of Lerak (Sapindus rarak) fruit rinds extract (ESR and synthetic additives in the form of N,N-dimethylurea (DMU) compounds in the zinc electrodeposition process on iron plates was carried out at room temperature. The results of this study show that the electrodeposition of zinc in electrolyte solution treated with Sapindus rarak extract additive gives a more visually uniform and compact coating morphology based on optical microscopy observations coating product than the electrodeposition product without additive or using N,N-dimethylurea additive. This has been observed using the naked eye and supported by observations under an optical microscope. The existence of zinc coating on the surface of the iron plate is supported by an increase in material thickness (control: 0.051 mm), (DMU: 0.025 mm) and (ESR: 0.028 mm) and an increase in material weight (control: 0.085 g), (DMU: 0.074 g) and (ESR: 0.074 g). In conclusion, the addition of DMU and ESR reduced the thickness and mass gain compared with the additive-free control.
Improving Mechanical Properties of Bioplastics from Sweet Potato Peel Waste with CMC and Gum Arabic Deny Aditya Pratama; Dwi Saputri; Sani Sani; Lilik Suprianti
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.736

Abstract

Plastic waste continues to be an environmental issue in Indonesia, where the country ranks as the second-largest producer of plastic waste in the world. Bioplastics, derived from renewable materials such as starch, have the potential to serve as an alternative to conventional plastics. The objective of this research is to formulate biodegradable bioplastics utilizing sweet potato peel starch, carboxymethyl cellulose (CMC), and gum Arabic, with glycerol added as a plasticizer. Initially, extraction was performed to obtain starch from sweet potato peels. Subsequently, the bioplastic production process was carried out using the wet mixing followed by the casting method by mixing 5 grams of sweet potato starch with the CMC in various weights (0.1, 0.2, 0.3, 0.4, and 0.5 grams) and gum Arabic (1, 1.5, 2, 2.5, and 3 grams). Mechanical property tests were conducted to evaluate the quality of the bioplastics, including tensile strength, elongation, and apparent modulus. The results indicate that higher concentrations of CMC and gum Arabic enhance tensile strength and rigidity, with a maximum tensile strength of 1.51 MPa achieved. However, increasing CMC concentration can reduce elongation properties. The bioplastics exhibited water absorption ranging from 15.3% to 81.3%, while biodegradability tests demonstrated that samples reached degradation levels of up to 93.8% within 28 days. This study demonstrates that sweet potato peel starch, combined with CMC and gum Arabic, can produce bioplastics with favorable mechanical properties and environmental friendliness, thus presenting a potential alternative method for reducing plastic pollution in Indonesia.
In Silico Investigation of EDTA-Functionalized ZSM-5 as a Rifampicin Drug Delivery System Against Tuberculosis-Related Targets Indra Lasmana Tarigan; Nadia Rahmasari; Chairanisa Intan Kartika; Jonathan Sabar Simorangkir; Ailsa Putri Dyanti; Muhammad Irfan Nur Widad
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.854

Abstract

Tuberculosis (TB) is a major infectious disease caused by Mycobacterium tuberculosis. Rifampicin is one of the primary anti-tuberculosis drugs; however, its clinical use is associated with gastrointestinal side effects and instability under acidic gastric conditions. Therefore, this study investigated the potential of an EDTA-functionalized ZSM-5 system as a rifampicin delivery carrier through an in silico approach. The study employed network pharmacology, Ramachandran analysis, molecular docking, toxicity prediction, and semi-realistic DFT-predicted electronic property analysis. Network pharmacology identified Cathepsin K (CTSK), BCL2, BCL2L1, and MCL1 as potential tuberculosis-related protein targets of rifampicin. Molecular docking showed that free rifampicin exhibited binding affinities of −9.1, −6.4, −9.7, −6.9, and −7.0 kcal/mol against CTSK, BCL2, BCL2L1, MCL1, and Mycobacterium tuberculosis, respectively. Meanwhile, the ZSM-5–EDTA–rifampicin complex showed binding affinities of −5.9, −5.6, −6.1, −6.0, and −7.3 kcal/mol, indicating that the complex maintained favorable interactions with tuberculosis-related targets. The proposed interaction model suggested that rifampicin could be retained within the porous ZSM-5 framework through hydrogen bonding and non-covalent interactions. In addition, the semi-realistic DFT-predicted HOMO–LUMO analysis indicated relatively stable electronic properties with an estimated energy gap of 4.34 eV. Toxicity prediction classified the rifampicin complex as mutagenic but non-carcinogenic. Overall, these findings suggest that the ZSM-5–EDTA system has potential as a controlled rifampicin delivery platform and may support further development of tuberculosis drug delivery systems.
Cytotoxic Activity of Chromolaena odorata Ethyl Acetate Fraction and Its Inhibitory Mechanism Through Cell Cycle Modulation Against WiDr Colon Cancer Cells Asniar Pascayantri; Hasnawati Hasnawati; Dian Munasari Solo; Nurramadhani A. Sida; Wa Ode Nurhayati Basri; Sarida Sarida; Aisyah Aisyah; Nurul Azizah Putri Herina; Muhammad Bagas Rahya Arafat
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1057

Abstract

Chromolaena odorata has traditionally been used to treat various diseases such as bacterial and fungal infections, external wounds, stomach ulcers, and vomiting blood. Its anticancer activity has been extensively studied. This study aims to prove the cytotoxic effect of Chromolaena odorata leaves on WiDr colon cancer cells and its inhibitory mechanism through cell cycle modulation. Dried Chromolaena odorata leaves were extracted by maceration using 96% ethanol. They were then triturated with n-hexane and ethyl acetate to obtain n-hexane and ethyl acetate fractions. The ethyl acetate fraction was then screened for phytochemicals using the tube method and tested for cytotoxicity using the MTT assay. The selectivity index (SI) was calculated by comparing the IC50 of WiDr cells to Vero cells. Cell cycle modulation was then observed using flow cytometry. The results showed that the ethyl acetate fraction of Chromolaena odorata leaves contained flavonoids, phenolics, and tannins, and was moderately cytotoxic to WiDr cells with an IC50 of 207.69 µg/mL,, with an SI of 3.5. The ethyl acetate fraction of Chromolaena odorata was able to inhibit the growth of WiDr colon cancer cell division through the G2/M and Sub G1 phases. Thus, it was concluded that the ethyl acetate fraction of Chromolaena odorata has great potential to be developed as a candidate source of colon anticancer agents.
Analysis of Phenolic, Flavonoid Content, and Antioxidant Activity of Combination of Pumpkin Leaves (Cucurbita moschata Durch.) and Aibika Leaves (Abelmoschus manihot L.) Fractions Ari Sartinah; Yamin Yamin; Hasnawati Hasnawati; Suryani Suryani; Nur Illiyyin Akib; Hikmawati Supu
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1058

Abstract

This study aims to determine the total phenolic and flavonoid content of ethyl acetate fractions from pumpkin (Cucurbita moschata Durch.) and aibika (Abelmoschus manihot L.) leaves, and to evaluate the antioxidant activity of their combined fractions. Analysis of total phenolics and flavonoids content was carried out using UV-Vis spectrophotometry with gallic acid (phenolics) and quercetin (flavonoids) as standards. Antioxidant potential testing was carried out using the DPPH method. The results showed that the phenolics content of the ethyl acetate fraction of PLand ALwas 60.81 and 56.47 mgEAG/g, respectively, while the total flavonoids content of the ethyl acetate fraction of PLand ALwas 64.54 and 55.07 mgEK/g, respectively. The IC50 value of the combination of ethyl acetate fractions of PLand ALwith a ratio of 3:2 was 4.686 μg/mL, while the single ethyl acetate fractions of PLand ALwere 7.040 and 7.549 μg/mL, respectively. This indicates that increasing antioxidant activity can be done by combining fractions from two or more types of plants.
Development of Smart Packaging Halochromic Film based on Jali Seed Flour (Coix lacryma-jobi) and Kencana Ungu Flower Extract (Ruellia simplex) Ali Kusrijadi; Zackiyah Zackiyah; Permata Maratussolihah
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1073

Abstract

The spoilage of marine products such as fresh shrimp is characterized by an increase in pH as a result of protein degradation which produces biogenic amines which are harmful if consumed. Simple early detection of damage can be done using smart packaging halochromic film. The purpose of this research is the synthesis, characterization and ability testing of smart packaging halochromic film is based on jali seed flour (Coix lacryma-jobi) embedded with anthocyanin pigments of Ruellia simplex flower extract (EBRS) as a natural indicator. There are two stages in the research method, the first stage includes the extraction and characterization of anthocyanins from Ruellia simplex flowers. The second stage is the synthesis, characterization and testing of the halochromic film capability of jali seed flour-EBRS film. Measuring Total Anthocyanin Content content in Ruellia simplex flowers extract uses the differential pH methods the anthocyanin is 1.037 mg/L. Sensitivity Test of Ruellia simplex Flower Extract to pH indicate contains pigments and is sensitive to changes in pH from 1-12, and gradual discoloration from magenta to purple, colorless, blue, green, and yellow. Smart packaging halochromic film were made using varying EBRS concentrations of 6%, 8%, and 10% (w/w), The ability of the EBRS halochromic film to change pH from 1 to 12 was obtained by the 8% EBRS halochromic film being the best in inform of discoloration. Characterization of 8% (w/w) EBRS halochromic film compared with standard film showed that the addition of EBRS reduced tensile strength values, increased solubility properties, swelling but did not affect the thickness and water rate transmission properties. The EBRS 8% (w/w) indicator film test showed that the indicator film was able to communicate early detection of shrimp damage.
Effects of Germination and Fermentation on Fatty Acid Profiles of Legume-Based Tempeh: A Systematic Review with Perspective on Cardiovascular Health Salma Muti Hafizha; Siti Aisyah; Asep Kadarohman
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1091

Abstract

Legume-based tempeh is a fermented food with the potential to support a healthy dietary pattern because it contains important nutritional components, including fatty acids. Germination and fermentation are known to influence lipid composition and fatty acid profiles in legumes, thereby potentially improving their nutritional value from a cardiovascular health perspective. This systematic review aimed to evaluate the effects of germination, fermentation, and their combination on the fatty acid profiles of legume-based tempeh. The PRISMA method was used to select and review 14 articles retrieved from the ScienceDirect and Scopus databases. The findings indicate that germination and fermentation can modify the fatty acid profile of tempeh, particularly through changes in saturated and unsaturated fatty acid contents. Several studies reported a decrease in saturated fatty acids and an increase in unsaturated fatty acids, including oleic acid, linoleic acid, and linolenic acid, although the magnitude of these changes varied depending on the type of legume, germination time, fermentation duration, microorganism, and analytical method used. Among the tempeh varieties reviewed, cowpea tempeh subjected to 24 h germination followed by 24 h fermentation showed a relatively favorable fatty acid profile, characterized by increased unsaturated fatty acids and an estimated linoleic acid to linolenic acid ratio of approximately 2.3:1.
Synthesis and Characterization of Ca2Al2SiO7:Pr3+ Photoluminescence Materials via Sol-Gel Method Maura Vanessa; Nirwan Susianto; Aep Patah
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1093

Abstract

Ca2Al2SiO7:Pr3+ is a potential UV-C-emitting material due to its photoluminescence properties. In this study, Ca2Al2SiO7:Pr3+ was synthesized via the sol-gel method as an alternative to the solid-state reaction method, which is energy-intensive and often yields low-quality phases. The synthesized products appeared as white powders for the undoped samples and pale green powders for the Pr³⁺-doped samples. XRD characterization showed that the optimum synthesis conditions were achieved at pH 5 with a calcination duration of 10 hours, yielding the highest-quality phase. Optical and photoluminescence characterization revealed a maximum UV-C emission at 273 nm and a band gap energy of 3.92 eV at a Pr³⁺ doping concentration of 7.25% moles.

Page 16 of 17 | Total Record : 162

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