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<![CDATA[Kadar Plumbum Pada Pasta Gigi Cangkang Anadara granosa Dengan Penambahan Citrus medica ]]>
<![CDATA[Sri Vanrovia Usman]]>;
<![CDATA[Margaretha Solang]]>;
<![CDATA[Syam S. Kumaji]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13511
<![CDATA[This study aims to determine the effect of adding suanggi orange juice (Citrus medica) to the lead content of blood clam shell toothpaste (Anadara granosa). The research was carried out at the Laboratory of the Department of Biology, FMIPA, state University of Gorontalo. This study used a completely randomized design (CRD) consisting of 4 treatments and 3 replications. Data analysis used One Ways Analysis of Variance and Duncan’s test at 5% level. The result showed that the addition of suanggi orange juice reduced the levels of lead in blood clam shell toothpaste (Anadara granosa). The addition of suanggi orange juice significantly reduced the levels of lead (p=0.000). the lead content of toothpaste added with 6 mL of orange suanggi is 0,036 ppm and is below the limit for Pb contamination on toothpaste according to SNI 8816:2020 which is 20.0 mg/kg.]]>
<![CDATA[Formulasi Sediaan Emulsi Mengandung Astaxanthin dari Ekstrak Minyak Virgin Coconut Oil Cincalok ]]>
<![CDATA[Indah Aprianti]]>;
<![CDATA[Siti Nani Nurbaeti]]>;
<![CDATA[Hadi Kurniawan]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13635
<![CDATA[Cincalok is a fermented product made from small shrimps and is a traditional food from West Kalimantan, Indonesia. Cincalok fermentation is produced with the composition of sugar and salt and the appropriate fermentation time. Shrimp in general contain several active compounds, one of which is astaxanthin which gives shrimp its red colour. The shrimp fermentation process resulted in an increase in astaxanthin concentrations compared to ordinary shrimp, caused by the breaking of protein bonds in the fermentation process. Virgin coconut oil is used for astaxanthin extraction because of its good solubility in oil. The emulsion formulation was carried out using 2 different non-ionic emulsifiers to see the effect of the emulsifier on the physical dan chemical properties and stability of the emulsion. Emulsifiers used are cremophor RH 40 and tween 80. The evaluation includes organoleptic testing, determination of content, pH, emulsion type, globule size and distribution of globule size, and viscosity. Stability evaluation were also carried out including volume creaming, centrifugation, heating and cooling, and freeze-thaw tests. The results and data showed that the emulsion formula using emulsifier tween 80 was more physically stable than the formula using cremophor RH 40]]>
<![CDATA[Analisis Kadar Senyawa Rhodamin B Pada Sediaan Lipstik Menggunakan Metode Spektrofotometri UV-Vis ]]>
<![CDATA[Faramita Hiola]]>;
<![CDATA[Mahdalena Sy Pakaya]]>;
<![CDATA[Juliyanty Akuba]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 3, No 2 (2021): Volume 3 Edisi 2 2021 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v3i2.13598
<![CDATA[Rhodamine B is a syntheticdye use in paper, textile, and ink dyes. This compound can irritate the respiratory tract and cause cancer with liver damage. The present study aimed to find out the levels of rhodamine B contained in lipstick. It relied on qualitative and quantitative testing. The qualitative testing applied the thin-layer chromatography method with ethyl acetat eluent: n-buthanol : ammonia with the best ratio of 20:55:25. Meanwhile quantitative testing used the UV-Vis Specrophotometry method. It was shown from the quantitative test using thin-layer chromatography that three samples of lipstick contained rhodamine B. Further, the quantitative test with the UV-Vis spectrophotometry indicated that the levels of rhodamine B were measured at 6.62 µg/mL with 0.662%]]>
<![CDATA[EVALUASI KESESUAIAN PENYIMPANAN OBAT DI SALAH SATU APOTEK KOTA CIMAHI ]]>
<![CDATA[Elis Susilawati]]>;
<![CDATA[ED. Yunisa M.P]]>;
<![CDATA[Deti Siti Fatimah]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13483
<![CDATA[Storage is one of the main factors in the maintenance of drug quality by storing properly and in accordance with standards, if it is not done will cause the quality of the drug is not guaranteed during storage in pharmacies. This study aims to find out how to store drugs and how much percentage of suitability of drug storage systems in one of Cimahi City Pharmacies Based on the Technical Instructions for Pharmaceutical Service Standards in Pharmacies in 2019. Research methods use descriptive observation and evaluation using checklist table sheets. Drug storage in one of Cimahi City Pharmacies is stored based on dosage form, therapeutic class, stability and alphabetically with a dispensing system using the FEFO system. Drug storage systems in pharmacies in accordance with the Technical Instructions of Pharmaceutical Service Standards are 86.36% while those that are not in accordance with the Technical Instructions of Pharmaceutical Service Standards which amount to 13.64% include adjacent LASA or NORUM storage, recording on less than optimal stock cards and the absence of backup electricity. The conclusion of this study shows that there are still those who are not in accordance with the Technical Instructions of Pharmaceutical Service Standards.]]>
<![CDATA[Pengaruh Iklan Obat Diare di Televisi Terhadap Keputusan dan Ketepatan Swamedikasi ]]>
<![CDATA[Fitrichia Febriyani]]>;
<![CDATA[Susan Fitria Candradewi]]>;
<![CDATA[Ana Hidayati]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13538
<![CDATA[Self-medication is one of the efforts that is mostly done by a person in overcoming the symptoms of a minor illness that he is suffering from before consulting a health worker. The results of the 2014 National Basic Reasearch showed that the percentage of the population who chose self-medication or self-medication due to health complaints experienced was 61.05%. Many factors influence people to take treatment, one of which is advertising. The purpose of the study was to determine the relationship between the effect of drug advertising on drug selection decisions and the accuracy of self-medication actions in the community in Umbulharjo District, Yogyakarta City. The design of this study was analytic observational with cross-sectional data collection. The sampling technique used incidental sampling method and data were collected through filling out a validated questionnaire. Data analysis was carried out with univariate and bivariate tests using SPSS 20.0. The results showed that the results of the significance test between the effect of drug advertisements on television on the accuracy of self-medication was 0.864. The conclusion of this study is that advertising has no significant effect on the appropriateness of self-medication (p 0.05).]]>
<![CDATA[Formulasi Sediaan Sabun Mandi Padat Dari Ekstrak Etanol Daun Kedondong (Spondias pinnata (L.f) Kurz) ]]>
<![CDATA[Hasma Hasma]]>;
<![CDATA[Erna Kadrianti]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13513
<![CDATA[Healthy skin is an element of female beauty. The thing that supports it is with cosmetics. The rise of the "back to nature" lifestyle has increased public confidence in cosmetics with natural ingredients. Cosmetics with natural ingredients are claimed to be safer to use on the skin than cosmetics using synthetic chemical compounds. Research has been carried out with the title "Formulation of Solid Bath Soap from Ethanol Extract of Kedondong Leaves (Spondias pinnata (L.f) Kurz)". This study aims to determine whether the formulation of solid bath soap from Kedondong (Spondias pinnata (L.f) Kurz) Leaf Ethanol Extract meets the criteria for quality requirements of pH, water content and high foam. The extract concentrations used were F1(3.5), F2 (7) and F3 (10.5). From the results of the research that has been carried out, it is obtained that the solid soap preparations F1 (3.5), F2 (7) meet the quality criteria test for pH, water content and foam height both before and after the cycling test. While the soap in FIII (10.5) met the water content and high foam test, but did not meet the pH quality standard for solid soap. Based on the results of this study, it can be concluded that from the three formulas above, the soap in FI and FII is a soap that meets the quality standard test of pH, water content and high foam. While the soap in FIII is soap that does not meet the required solid soap pH quality standard.]]>
<![CDATA[Uji Toksisitas Ekstrak Etanol Kulit Terong Ungu (Solanum melongena L.) Menggunakan Metode Brine Shrimp Lethality Test (BSLT) ]]>
<![CDATA[Nur Rahma Dwi Cahya]]>;
<![CDATA[Widy Susanti Abdulkadir]]>;
<![CDATA[Hamsidar Hasan]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13630
<![CDATA[Purple eggplant skin (Solanum melongena L.) is one of the herbal plants that contain compounds such as flavonoids, alkaloids, saponnins, tannins, and terpenoids that are beneficial for health. This research is a laboratory experimental study that aims to determine the level of acute toxicity (LC50) of the ethanol extract of purple eggplant skin (Solanum melongena L.) using the Brine Shrimp Lethality Test (BSLT) method. Purple eggplant peel extraction was carried out using 70% ethanol as solvent. This test was conducted using 10 Artemia salina Leach larvae with 3 replications at 6 concentration variants, which are 500 ppm, 250 ppm, 125 ppm, 50 ppm, 25 ppm, and 12.5 ppm, along with negative controls. The larval mortality rate was observed after 24 hours of adding extract. The result of probit analysis showed that the LC50 value of the ethanol extract of purple eggplant skin (Solanum melongena L.) was 100.8 ppm. Moreover, the results of LC50 1000 ppm indicated that the ethanol extract of purple eggplant skin (Solanum melongena L.) was considered toxic and potential to be an anticancer agent.]]>
<![CDATA[Efek Bunga Telang (Clitoria ternatea L.) Terhadap Kolesterol Total, LDL, HDL Pada Tikus (Rattus Norvegicus ) ]]>
<![CDATA[Yustiyani Arifah]]>;
<![CDATA[Sunarti Sunarti]]>;
<![CDATA[Rani Prabandari]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13493
<![CDATA[Dyslipidemia is an abnormality of lipids in the blood, including a decrease in HDL levels and an increase in triglyceride levels, LDL levels and total cholesterol. The high concentration of cholesterol in the blood is one of the causes of atherosclerosis and can further cause hypertension and coronary heart disease. The use of synthetic drugs in the long term can cause unwanted side effects. This study aims to examine the effect of increasing HDL cholesterol levels, decreasing total cholesterol and LDL cholesterol levels from the ethanol extract of Clitoria ternatea L using male rats (Rattus norvegicus). This study used the maceration method of Clitoria ternatea L. then the thick extract obtained was tested for its activity which was divided into 6 treatment groups namely normal control group, positive control, negative control, dose 1 (extract 100 mg/kgBB), dose 1 2 (extract 200 mg/kgBB) and dose 3 (extract 400 mg/kgBB) were then measured for total cholesterol, HDL and LDL. The results showed that the administration of ethanol extract of Clitoria ternatea L was able to reduce total cholesterol levels, LDL and increase HDL levels in male rats. The dose of ethanol extract of Clitoria ternatea L that was most effective in reducing total and LDL cholesterol levels and increasing HDL levels in rats that had been induced by a high-fat diet was dose 3, namely extract 400mg/kgBB.]]>
<![CDATA[Analisis Tingkat Pengetahuan dan Perilaku Swamedikasi Diare Selama Pandemi Covid-19 ]]>
<![CDATA[Filomina Dila Putri]]>;
<![CDATA[Shoma Rizkifani]]>;
<![CDATA[Hariyanto IH]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13599
<![CDATA[Diarrhea was determined as one of the Covid-19 symptoms and during the Covid-19 pandemic in 2020, the prevalence of diarrhea increased to 13.05% in district of Rasau Jaya. The limitations of health services during the Covid-19 pandemic led to the increasing of self-medication behavior, including self-medication to overcome those diarrheal symptoms. The object of this study was to determine the level of knowledge and behavior of self-medication for diarrhea in district of Rasau Jaya and the correlation between these knowledge and behavior. We use a cross sectional approach with total of 70 respondents and we use purposive sampling with a questionnaire measuring instrument for sampling technique as well. Data were measured by statistical tests of Spearman rank correlation. The results showed that 57.14% of respondents have a good level of self-medication knowledge whereas 41.43% and 1.43% of respondents have medium and deficient knowledge, respectively. These results are in line with self-medication behavior that shown 95.71% of respondents have a good level of behavior but only 4.29% of respondents have a deficient level. We found that People in Rasau Jaya had a good level of self-medication knowledge and behavior and there is a correlation between those two.]]>
<![CDATA[Gambaran Pengetahuan Masyarakat Terhadap Penggunaan Produk Pencerah Kulit ]]>
<![CDATA[Intan Normalita]]>;
<![CDATA[Ni made ayu Nila Septianingrum]]>;
<![CDATA[Widarika S anti Hapsari]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13520
<![CDATA[Beauty in Indonesia is often associated with white and clean skin. based on a report by the Food and Drug Supervisory Agency (BPOM) in 2015 there were 30 types or 17,000 dangerous cosmetic items which turned out to contain hazardous chemicals such as rhodamine B, hydroquinone, retinoic acid, and mercury which are widely contained in face whitening creams. The purpose of this study was to describe the level of public knowledge about the impact of using skin lightening cosmetics in Magelang. This research is an observational descriptive research using cross sectional method and sampling technique using snowball. The research instrument was in the form of a questionnaire distributed via a googleform link. A total of 110 respondents from Magelang City, 46 and 64 respondents from Magelang Regency participated in this study. As many as 80% of female respondents aged 16-25 years who use skin lightening products for 1 to 2 months (24.5%) %) with income 2,000,000 (68.20%) and spend one package of skin lightening products every month ( 37.27%) with an average cost of around Rp. 10,000 – Rp. 200,000 rupiah and the most used up front (83.60%) . Respondents got cosmetics from cosmetic shops (63.60%) and as many as 50% of respondents said their skin color would return to normal if they stopped using lightening creams. Respondents already know that mercury (70%) is one of the harmful substances in whitening creams and its excessive side effects will endanger skin health (95.5%).]]>
