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JURNAL FARMASIMED (JFM)
Published by Institut Kesehatan Medistra Lubuk Pakam
ISSN : -     EISSN : 26550814     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Jurnal FARMASIMED (JFM) Volume I Nomor 1 Periode Mei - Oktober Tahun 2018. Jurnal ini memberikan ruang bagi akademisi, peneliti dan pengguna hasil penelitian dan pengabdian untuk mendiseminasikan, menginformasikan, mendiskusikan dan menggunakan hasil penelitian dan pengabdian sebagai upaya meningkatkan kualitas kebijakan di bidang farmasi yang berbasis ilmiah dan dapat dipertanggung jawabkan. Jurnal ini menyajikan hasil penelitian, pengabdian masyarakat serta artikel ilmiah di bidang farmasi.
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Articles 33 Documents
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Search results for , issue "Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)" : 33 Documents clear
Dragon Fruit Peels Waste as Cosmetic: An Overview Fatimi, Hana Anisa; Ramadhana, Irma Hazira Awalinda; Purnama, Magnifico Fatta
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2464

Abstract

Dragon fruit peels (Hylocereus polyrhizus) have various potential as a base ingredient in eco-friendly cosmetic products. This study focused on evaluating the bioactive properties of dragon fruit peels, finding that the compounds contained therein are more effective in counteracting free radicals than the flesh of the fruit. Data collection techniques were carried out by literature study and digital information search with the target objectives in the form of literature study (literature review) searching for information from relevant literature sources for two week in November - December 2024 by searching >30 references from Google Scholar, ResearchgateNet and Sciencedirect, Sinta, MDPI, Pubmed. As well as, official websites in the range of 2014-2024. Literature study was conducted by identifying problems regarding the content of different formulations. The method was through a qualitative approach, which is descriptive research and tends to use analysis. Dragon fruit peel extract showed significant activity in preventing skin damage caused by UV rays and pollution. This innovation not only provides a solution for agro-industrial waste reduction, but also creates sustainable cosmetic products with high economic value. This waste utilization supports the consumer trend towards products based on natural and environmentally friendly ingredients From this review, dragon fruit peels have a great opportunity to be used as an active ingredient in various types of cosmetic products, such as moisturizers, serums, creams, and face masks, with a positive impact on skin health and the environment.
Pharmacognostic Identification and Specific Quality Parameters of Blue Porterweed (Stachytarpheta jameicensis) Leaf Extract from Enrekang Regency, South Sulawesi amin, asni; Risda Waris; Noer Kurnia; Nur Fadilla
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2477

Abstract

The leaves of Blue Porterweed (Stachytarpheta jamaicensis) are commonly found in Enrekang district and used as medicinal plants. Its pharmacological effects have been tested invitro and invivo. However, data on the quality of this extract is still unpublished. This study was conducted to identify the pharmacognostic and specific quality parameters of horse whip leaf extract from Enrekang district. The research method is laboratory experimental. Pharmacognostic identification was carried out by identifying plant morphology, macroscopic test of simplisia, and identification of chemical content by Thin Layer chromatography (TLC). The extract obtained from maceration using 70% ethanol and then determined its specific parameters including organoleptic tests, extract identity parameters, soluble extract content in certain solvents. The results of pharmacognostic identification that have been carried out show that horse whip is a shrub, 50 cm-1.2 m high, taproot, lanceolate leaf, serrated edges, pinnate leaf repetition and belongs to the Verbenaceae family, and the TLC results of the extract show the presence of alkaloid, phenol, and flavonoid compounds. The identity name of the extract is Stachytarpetae Folium Extractum, black brown in colour, thick extract texture, slightly bitter taste, and weak odour. Test results of water soluble extract content = 14.96% and ethanol soluble extract content = 15.23%. Conclusion: Data on specific quality parameters of blue porterweed leaf extract will be a reference for the manufacture of standardised herbal medicine.
Analysis of Improvement in Pharmacy Services Based on The IPA Model At Pharmacy X Ijen Malang Dian Nurmawati; Arifani Siswidiasari; Rahmaweni
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2580

Abstract

Patient satisfaction is pleasure after receiving services that meet or exceed expectations. Patient satisfaction surveys should be conducted at Apotek at least once every 6 months, including Apotek Kimia Farma 36 Ijen. Pharmaceutical services are direct and responsible services to patients related to pharmacy to achieve tangible results and improve the patient's quality of life. This research aimed to measure patient satisfaction with pharmaceutical services at Apotek Kimia Farma 36 Ijen. The method used is descriptive research with a quantitative approach through a questionnaire instrument using the SERVQUAL (Service Quality) model with incidental sampling techniques. The statement on the questionnaire that had the highest satisfaction was the pharmacist who did not look at the patient's social status and the friendliness of the pharmacy staff. In contrast, the lowest satisfaction was the statement of quality drug supply. The research results showed that patients were satisfied with pharmaceutical services at Kimia Farma 36 Ijen Pharmacy by obtaining a satisfaction level of 68.39%.
Overview of Therapy and Medication Adherence in Outpatient Post-Stroke Patients at RSUD Taman Husada Bontang Fauzi, Lailla Affianti; Kushartanti, Wara; Arovah, Novita Intan
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2585

Abstract

  Background: Stroke is a cerebrovascular disease that can cause physical and cognitive impairments, including a high risk of depression. Medication adherence plays a crucial role in preventing complications and improving patients' quality of life. Objective: This study aims to describe the therapy and evaluate medication adherence among post-stroke outpatients in the recurrent and non-recurrent stroke groups at RSUD Taman Husada Kota Bontang. Methods: This study employs a cross-sectional design, involving a total of 152 patients, consisting of 119 non-recurrent stroke patients and 33 recurrent stroke patients. Data were collected through interviews, secondary data retrieval from medical records, and primary data obtained from the MMAS-8 (Morisky Medication Adherence Scale-8) questionnaire to assess medication adherence levels. Data were analyzed descriptively, and a chi-square test was performed to examine the association between medication adherence and stroke recurrence. Results: The findings indicate that both recurrent and non-recurrent stroke groups were prescribed antiplatelet, anticoagulant, neuroprotective, and antihypertensive drugs. Additionally, lower medication adherence was more frequently observed in recurrent stroke patients compared to non-recurrent stroke patients (24% vs. 26%). Analysis of the MMAS-8 questionnaire items revealed that forgetting to take medication occurred in both groups, but was more common among non-recurrent stroke patients (23% vs. 9%). Conclusion: This study highlights the need for continuous monitoring of therapy profiles and efforts to improve medication adherence to prevent further complications in post-stroke patients. The findings emphasize the importance of ongoing evaluation and innovative medication education for post-stroke patients.
Exploration of Local Knowledge of Ethnomedicine and Medicinal Plants on Nias Island Dachi, Kanne; Tambunan, Ika Julianti
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2586

Abstract

Background: The use of plants in Indonesia has been carried out for generations, especially as part of traditional medicine. This traditional medicine is still a very valuable national asset and continues to be used by communities throughout Indonesia. One of them is the Nias tribal community in North Sumatra, where around 50% of them still use and care for medicinal plants which are considered more effective and economical as treatment in their own environment. Objective: The aim of this research is to find out the various types of plants used by the people of Nias, North Sumatra, how they are processed, and which parts of the plants are used for medicine. Methode: The research method used is a combination of qualitative and quantitative methods which are explained descriptively. Data collection techniques include interviews, observation and documentation. Meanwhile, data analysis techniques include data collection, data condensation, data presentation, and drawing conclusions. Result: The research results showed that there were 46 types of medicinal plants obtained from the results of a questionnaire to the community, with a total of 20 informants from 5 villages spread across Nias Regency, North Sumatra. Traditional treatments still practiced by the people of Nias include boiling, squeezing, pounding, burning and soaking. The way it is served also shows a high level of knowledge about medicinal ingredients, such as drinking, sticking or applying, compressing, bathing, eating and applying. Conclusion: The reason for using this traditional medicine is because it is considered cheaper, easier, safer and has minimal side effects.
Antihyperuricemia Activity Test of Tempuyung Leaf Infusion (Sonchus arvensis L.) on Male Swiss Webster Mice (Mus musculus) Estevany Priliansi; Sarah Puspita Atmaja; Ari Widhiarso
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2588

Abstract

Background: Treatment of hyperuricemia with allopurinol has a risk of hypersensitivity reactions that can be fatal with mortality rates reaching 20%-25%. As an alternative, tempuyung leaves (Sonchus arvensis L.) are known to contain flavonoids that have the potential to reduce uric acid levels. Objectives: To identify chemical compounds and evaluate their effects as antihyperuricemia. Methodology: A laboratory experimental study conducted for 14 days using male mice. The mice were divided into several groups, namely the negative control (Na-CMC 0.5%), positive control (allopurinol), and groups treated with Sonchus arvensis leaf infusion at doses of 50 mg/kg BW, 100 mg/kg BW, and 150 mg/kg BW. Hyperuricemia induction was performed for 7 days using potassium oxonate and chicken liver juice. Uric acid levels were measured using an enzymatic method with a UV-Vis spectrophotometer. Data analysis was performed using Paired T-Test and One-Way ANOVA statistical tests. Result: The infusion of Sonchus arvensis L. leaves indicates the presence of flavonoids, alkaloids, saponins, and tannins. The highest uric acid-lowering effect appears at a dose of 150 mg/kg BW, with a reduction of 26.517%. All doses of the infusion show a significant decrease in uric acid levels, both after hyperuricemia induction and on days 7 and 14 of treatment. A significant difference in uric acid reduction between groups appears at doses of 50 mg/kg BW and 100 mg/kg BW, while the dose of 150 mg/kg BW does not show a significant difference.
Comparison of Different Extraction Methods on Sorghum Seeds (Shorgum bicolor (L). Moench) on Extract Yield and Secondary Metabolite Compound Levels Maramis, Rilyn Novita; Nahor, Evelina Maria; Rindengan, Elvie Rifke
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2592

Abstract

Sorghum, as a potential crop, has been promoted by the government as a national food source. Sorghum contains primary metabolites such as carbohydrates, proteins, and high fiber, as well as secondary metabolites including alkaloids, tannins and phenols, steroids, and terpenoids. The secondary metabolites produced and the yield obtained depend on the extraction method used. This study aimed to determine the yield and concentration of sorghum seed extract obtained through cold extraction (Percolation) and hot extraction (Reflux). Sorghum seed extract was obtained using cold (Percolation) and hot (Reflux) extraction methods with 96% ethanol as the solvent. The resulting yield was then calculated, followed by identification and quantification using UV-Vis spectrophotometry. The results show that the cold extraction (Percolation) method produced a yield of 3,733%, while the hot extraction (Reflux) method produced a yield of 10,133%. The identification of secondary metabolites in sorghum seed extracts from both cold (Percolation) and hot (Reflux) extraction methods reveals the presence of saponins, flavonoids, tannins, and terpenoids, but no alkaloids or steroids. The percolation method yields a total saponin content from Quillaja bark of 0,94% w/w, a total flavonoid content equivalent to quercetin of 0,84% w/w, and a total tannin content equivalent to tannic acid of 0,45% w/w. Meanwhile, the reflux extraction method yields a total saponin content from Quillaja bark of 1,07% w/w, a total flavonoid content equivalent to quercetin of 0,0615 %b/b, and a total tannin content equivalent to tannic acid of 19,44% w/w.
Profile of Suaitabilit of BPJS Patient Drug Prescription With The National Formularium at Juata Community Health Center During The Periode of May-July 2024 Arny_, arnny pertiwi sari; Sari Wijayanti; Jufri Ubrusun
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2605

Abstract

Background: Compliance with the National Formulary not only improves the quality of health services in primary health facilities but also ensures the efficiency of treatment costs and the fulfillment of the right and safe drug needs for the community. This study supports efforts to strengthen the implementation of the National Formulary as a strategic guideline to increase access to quality health services, improve pharmaceutical governance, and encourage efficiency of the health budget. Objective: This study aims to assess the suitability of drug prescriptions for patients registered in the BPJS Kesehatan program in accordance with the National Formulary (Fornas) at the Juata Health Center during the period May to July 2024. Research Methods: The research design applied was non-experimental with a retrospective descriptive approach. A total of 300 BPJS patient prescriptions were selected as samples from a total population of 8704 prescriptions using the Slovin method with a precision level of 90%. Data were analyzed descriptively to calculate the percentage of prescription suitability based on prescription sheets and drug items. Results: The results showed that the suitability of prescriptions based on prescription forms and drug items reached 100% during the study period. Of the total 101 prescribed drug items (28 items in May, 41 items in June, and 32 items in July), all were based on the National Formulary. Conclusion: These results provide the conclusion that the Juata Health Center has met the standards of pharmaceutical services, with drug prescriptions that fully support rational, efficient, and effective drug use. The results of this study have significant relevance to national health policies, especially in the implementation of the National Health Insurance (JKN) program.
Evaluation of Skin Irritation Level and Effectiveness of Foot Sleeping Mask Containing Tengkawang Fat in Nanostructured Lipid Carriers System Fidayanti, Ayu; Mayangsari, Fransisca Dita; Pratiwi, Elasari Dwi
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2608

Abstract

One of the export commodities from the Non-Timber Forest Products (NTFP) group is tengkawang fruit. This fruit can be processed into fat which has properties similar to cocoa butter. The advantage of this fat compared to cocoa butter is that the price is relatively cheaper. However, the use of tengkawang fat in cosmetics is not widely known. Therefore, researchers are interested in developing cosmetic products based on tengkawang fat to treat xerosis of the feet. To increase occlusivity, tengkawang fat is formulated into an NLC (Nanostructured Lipid Carriers) system. In this research, a foot sleeping mask product was made containing NLC tengkawang fat with the addition of gel (to improve viscosity) and sweet orange oil (to improve aroma). The aim of this research was to determine the irritation skin level and effectiveness of moisturizing the skin of the soles of the feet from a foot sleeping mask containing NLC tengkawang fat. The results of the physical characteristics test show that the foot sleeping mask made meets the desired specifications. The results of skin irritation tests with 35 panelists showed that there was no redness or edema on the panelists' skin during 24, 48 and 72 hours of observation. The results of the moisture effectiveness test showed that the average moisture content of the soles of the panelists' feet on day 0 was 34.531%, while on day 28 (4 weeks) it was 42.815%. There was an increase in humidity of 8.284% during 4 weeks of use. The conclusion of this research is that a foot sleeping mask containing Tengkawang fat NLC can increase the moisture of the skin of the soles of the feet by 8.284% during 4 weeks of use.
A Review: Propolis As An Antiinflammatory Adjunct Therapy in Chronic Kidney Disease Depari, Elpiani; Malisie, Ririe Fachrina
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2613

Abstract

Chronic Kidney Disease (CKD) is a disease with abnormalities of the structure and function of kidney that last for at least 3 months and has an impact on health. Inflammation is a progression factor and outcome of CKD. Diabetes, hypertension, cardiovascular disease, exposure to environmental pollution and use of nephrotoxic drugs develop into CKD through inflammation. Inflammation in CKD caused complications in cardiovascular disease, bone mineral disorders, anemia and immune disorders, as well as reducing the patient's quality of life. Cardiovascular complications are the main cause of CKD patients’ death. Renal replacement therapy such as hemodialysis is not effective enough to overcome the inflammation, because unable to remove intermediate molecules and protein-bound molecules, the majority of which are inflammatory markers such as cytokines, namely TNF-?, IL-1, IL-6 and others. Propolis, a natural bee resin product, has anti-inflammatory effects, because it contains many bioactive phytochemicals such as flavonoids, phenolic acids, esters, diterpenes, aromatic aldehydes, amino acids, fatty acids, vitamins and minerals. It inhibits the production and release of cytokines through inhibiting NF-kB (nuclear factor kappa Beta) activity, reducing COX-2 expression and inhibiting nitric oxide (NO). Many clinical trials of propolis in CKD have been carried out and reported safe and beneficial, including in patients undergoing dialysis. Propolis has been proven able to reduce several inflammatory markers, such as TNF-?, interleukin and others. It has great potential as a safe additional therapy in CKD patients, both dialysis and non-dialysis.

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