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Jaringan Laboratorium Medis
Published by Poltekkes Kemenkes Semarang
ISSN : -     EISSN : 26858495     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Public Health
Jurnal Online Jaringan Laboratorium Medis adalah peer-reviewed journal yang mempublikasikan artikel-artikel ilmiah tentang ilmu kesehatan yang meliputi bidang Analis Kesehatan yang meliputi Penelitian Bakteriologi, Kimia Klinik, Parasitologi, Toksikologi Klinik, Hematologi, Sitohistoteknologi dan Imunologi, Teknologi Bank Darah. Dengan e-ISSN: 2685-8495 diterbitkan oleh Jurusan Analis Kesehatan Politeknik Kesehatan Kemenkes Semarang, terbit 6 bulan sekali, pada bulan Mei dan November setiap tahunnya.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 270 Documents
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Analisis Kadar Timbal (Pb) Darah dan Malondialdehid (MDA) Pada Manusia Silver di Kota Semarang Rosidah, Umi; Hadipranoto, Ichsan
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9519

Abstract

The danger of lead in paint that is coated on the human body, silver can enter through the skin and will interact with proteins, DNA, RNA and oxidative stress. Formation of Reactive Oxygen Species (ROS) by lead can cause oxidative stress and is characterized by an increase in the enzymes catalase, malondialdehyde (MDA) and Oxidized glutathione (GSSG). The aim of this study was to analyze blood lead levels against Malondealdehyde (MDA) in silver humans in Semarang City. This study used an observational analytic study with a cross sectional approach to analyze the effect of lead levels on Malondialdehyde levels in silver humans in Semarang City using a t test to see differences in results based on length of work, length of exposure and age on lead levels, and the effect of lead on MDA. The results showed that from 20 human samples, the lowest lead level was 23.9 g/dl and the highest was 61.9 g/dl with an average blood lead level of 37.3 g/dl with an average blood lead level of 37.3 g/dl, and the lowest MDA level was 0.4 mg/L and the highest level is 1.74 mg/L with an average of 1.2 mg/L. Based on the data obtained from the t test, it shows a significant value (P-Value) of 0.610 which means > 0.05, this indicates that the decision taken is to reject H1 which means that there is no effect between the results of lead levels on the results of MDA levels.
Hubungan Antara Kadar Asam Urat dengan Kepatuhan Minum Obat pada Pasien Tuberculosis Paru Auliya, Qurrotu A'yuni; Maulana, Mochamad Rizal; Priyatno, Djoko
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9545

Abstract

Tuberculosis lungs is disease infectious disease caused by bacteria Mycobacterium tuberculosis. TB disease still become threat health Indonesian society which leads to illness , disability and death tall so that need exists countermeasures. Research objectives know connection between rate sour tendon with obedience drink medication in pulmonary TB patients. Study This is study retrospective analytic observational with approach cross sectional, with use analysis Research Chi square test statistics conducted at the Ambarawa Community Health Center (BALKESMAS) in October 2022. Population all moderate pulmonary TB patients undergo treatment at BALKESMAS Ambarawa. Research sample This of the total population namely 30 patients. Results from 30 respondents there is rate sour veins in patients Tuberculosis lungs there is enhancement rate sour tendon namely 11 respondents that is man with average levels sour urate 7.08 mg/dL (6 respondents ), female with average level 6.41 mg/dL (5 respondents ). Based on forever drink drug obtained that amount patient with treatment >3 months 57%, 2-3 months 30%, and 1 month 13%. Based on characteristics that kind sex men 53% and kind sex women 47%. Based on characteristics age category teenagers 23%, adults 50% elderly 27%. Based on obedience drink anti-tuberculosis drugs by 28 respondents or 93.34% of total number of respondents . Whereas For respondents who did not obedient drink drug namely 2 respondents or 6.06%. Chi square test results on compliance status drink medicine, type gender, age No showing connection significant (P<0.05) against rate sour veins in patients Tuberculosis lungs. Research conclusions This No There is connection rate sour tendon with obedience drink medication in pulmonary TB patients, This caused by TB Treatment consists of over 2 stages that is intensive and advanced, function system immunity body relate with age, history of medication, obesity, consumption purines , and alcohol.
Faktor-faktor Risiko Kelainan Kadar Hemoglobin pada Pengendara Ojek Motor Online di Kawasan Industri Tanjung Mas Kota Semarang Setyowatiningsih, Lilik; Wikandari, Ririh Jatmi
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9564

Abstract

Air pollution can affect health conditions, CO and Pb are one of the compositions of vehicle exhaust gases that are dangerous. Online motorcycle taxi drivers have a high risk of exposure to pollutants. This research aims to determine the risk factors that affect hemoglobin levels in online motorcycle taxi drivers in the Tanjung Emas Area of Semarang City. The method used observational analytics with a cross-sectional approach. The total population in this study was 55 respondents and the number of respondents was determined using total sampling. Based on the results of examining hemoglobin levels using a hematology analyzer, of 55 respondents, 47 respondents had normal hemoglobin levels and 8 respondents had abnormal hemoglobin levels. The results of the Chi square test on smoking status have a significant relationship (p=0.04) to the blood hemoglobin level of online motorcycle taxis in the Tanjung Emas Area of Semarang city while in the status of Education, length of work, and knowledge there is no significant relationship (>0.05) to the hemoglobin level of online motorcycle taxi drivers in the Tanjung Emas Area of Semarang City. The conclusion of this study is that there is a significant relationship between smoking status and hemoglobin levels of online motorcycle taxi drivers in the Tanjung Emas Area of Semarang City and there is no significant relationship between education factors, length of work time, and knowledge of hemoglobin levels of online motorcycle taxis in the Tanjung Emas Area of Semarang City.
Gambaran Nilai Index Trombosit pada Pasien Tuberulosis Paru yang Mengonsumsi Obat Anti Tuberkulosis Widiyanto, S.Y. Didik; Qomariyah, Nurul; Sofyanita, Eko Naning
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9646

Abstract

Tuberculosis (TB) is a disease caused by the bacterium Mycobacterium tuberculosis which mostly attacks the lungs. Based on several studies, it is stated that tuberculosis sufferers who take OAT for healing experience side effects in the form of lowering the platelet index due to reactions from drugs that lyse platelets. This research is a descriptive study with a cross sectional design. Research was conducted on 30 respondents who consumed OAT. The results of this study obtained results of more than 50% on one of the platelet indices, namely the PWD value, which was obtained with low results with a total of 19 patients (63.3%), while for other indices such as platelet counts there were 21 patients (70%) , MPV in 28 patients (93%) and PCT in 23 patients (77%) had normal results. The conclusion of this study is that platelet index examinations in TB patients tend to be low in MPV and PDW, while they show high results in PLT and PCT examinations.
Skrining Gestational Diabetes Mellitus (GDM) pada Wanita Hamil dan Diabetes pada Lansia di Wilayah Getasan Widodo, Widodo; Riyadi, Ahmad; Widiyanto, S.Y. Didik; Ayuni, Aulia Qurotul
Jaringan Laboratorium Medis Vol. 5 No. 1 (2023): May 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i1.9661

Abstract

Type 1 and type 2 diabetes are influenced by genetic and environmental factors causing a decrease in β cell function resulting in hyperglycemia. Patients with hyperglycemia are at risk for chronic complications. The elderly have the potential to suffer from diabetes mellitus due to the age factor and the decreased ability of the body's metabolism. Whereas in pregnant women any hyperglycemia is considered gestational diabetes mellitus (GDM), regardless of diabetes occurring before or during the current pregnancy GDM is diabetes diagnosed in the second trimester or later. This study aims to map cases of diabetes and gestational diabetes. This research is a non-experimental study with a survey method approach without intervention that is descriptive analytic research results of 48 people with a total of 14 men and 5 pregnant women out of a total of 34 female respondents. Examination results for supporting examinations obtained the results of 8 glucose samples with levels > 200 mg/dl and those who had diabetes mellitus based on HbA1c examination were 6 people aged 45-65 years and as many as 3 people aged over 65 years. Respondents who had diabetes mellitus were 2 men and 4 women and none of the pregnant women had gestational diabetes. This research has an impact on the people who take part in this activity, one of which is getting education on how to maintain a healthy quality of life in old age and for those who enter the diabetes mellitus screening group, it is continued in the process of care and assistance by the Getasan Health Center.
Perbandingan Hasil Pemeriksaan Protein Urine Metode Carik Celup, Asam Asetat 6%, dan Asam Sulfosalisilat 20% Menggunakan Aturan Westgard Permata Sari, Cecilia Febiyono; Kahar, Fitriani; Irnawati, Irnawati; Yusuf, Muhammad; Salam, Abdul; Wadood, Abdul
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9784

Abstract

Proteinuria is caused by kidney damage. Qualitative examination of urine protein can be carried out using the dip strip method, 6% acetic acid and 20% sulfosalicylic acid. The aim of this research is to determine the accuracy and precision of urine protein examination using the dip strip method, 6% acetic acid and 20% sulfosalicylic acid. The research was experimental with repeated measurements of levels carried out visually and gave positive results of 1, 2, 3 and 4. The research was carried out in January 2022 using a research sample of 20 proteinuria positive patients at RSJD Dr. Amino Gondohutomo. The results of this research are that all methods meet the 12S rules where there is 1 control that is more than ± 2SD (still in the ± 3SD area), categorized as a warning/warning of method malfunction (needs more careful analysis). The best method is dip strip because it has the lowest Coefficient of Variation (KV) value, namely 0.497%. The method can still be used for patient care. The coefficient of variation obtained was dye liquid 0.497%, 6% acetic acid 0.654%, and 20% sulfosalicylic acid 0.630%. The smaller the KV value (%) the more thorough the system/method. The conclusion that can be drawn from this research is that the dip strip is a method that has the best accuracy and precision compared to the 6% acetic acid and 20% sulfosalicylic acid methods because it has the smallest coefficient of variation (KV%) value, namely 0.497% and meets the 12S rules. Researchers recommend always ensuring that the research location has the required samples with adequate volume, urine protein examination can be carried out using the dip strip method, researchers can then carry out urine protein examination regarding the sensitivity and specificity of the three qualitative methods
Perbandingan Persentase Risiko Meninggal pada Pasien Covid-19 Komorbid TBC dengan Komorbid Lainnya di Kabupaten Pati Istananta, Randi Eka; Budiharjo, Teguh; Surati, Surati
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9829

Abstract

Corona Virus Disease 2019 (COVID-19) is a disease that has never previously been found in humans and is a new type of disease. The virus that causes COVID-19 is called Sars-CoV-2. It was found that patients experienced increased mortality due to COVID-19 because they had comorbid diseases. COVID-19 patients who have one comorbid disease are at risk of death up to 6.5 times higher than COVID-19 patients without comorbidities. Pulmonary TB is a comorbidity that can make a person more susceptible to contracting COVID-19 with severe symptoms. Apart from attacking the lungs, COVID-19 also damages the lungs. Damaged lungs prevent the body's organs from getting enough oxygen, which can trigger organ damage that can cause death. The aim of this study was to compare the percentage risk of death in COVID-19 patients who had comorbid TB disease with COVID-19 patients who had comorbid kidney disease and DM in the Pati area, Central Java. This research can be a reference for data regarding the percentage risk of death in COVID-19 patients with comorbidities. This research uses a descriptive, observational research design. The samples in this study were COVID-19 sufferers who had comorbid TB, comorbid kidney disease and comorbid DM. The sample population during the period January to December 2021 was 998. The sample was determined using the Slovin formula with a total of 135 samples with a sampling quota taken. Results Comorbid TB has a percentage risk of death of 40%, comorbid kidney has a percentage risk of death of 33.3%, and comorbid DM has a percentage risk of death of 6.8%. Comorbid TB is a comorbid that has the highest percentage risk of death, so intensive care is important for sufferers.
Kasus Reaksi Transfusi pada Pasien Penerima Donor Darah di RSUD Sayang Kabupaten Cianjur Periode 2020-2022 Purlinda, Devi Etivia; Nurhamida, Tsani Nisa
Jaringan Laboratorium Medis Vol. 6 No. 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.9899

Abstract

Blood transfusions must be performed based on appropriate indications, selecting the correct volume and type of component, and administered at the right time. The risk of transfusion reactions is inherent in nearly every transfusion process and can manifest clinical symptoms in patients. Hospitals must conduct oversight of the blood transfusion process, known as hemovigilance, to prevent transfusion reactions and enhance the safety of blood services. This study aims to determine the number of transfusion reaction cases in blood donor recipients at RSUD Sayang, Cianjur Regency, during the period from 2020 to 2022. This qualitative research utilizes a total sampling technique. The population comprises all blood donor recipients at RSUD Sayang, Cianjur Regency, from 2020 to 2022. The sample includes medical records data of transfusion reaction cases in blood donor recipients at RSUD Sayang, Cianjur Regency, from 2020 to 2022. The results indicate 35 cases of transfusion reactions. The majority of transfusion reaction cases in blood donor recipients were acute category I (mild) reactions, totaling 21 cases (60%). Patients with a history of previous transfusions predominantly experienced category I (mild) and category II (moderate) reactions, each with 12 cases (57.1%). Most acute reaction cases were category I (mild), with 20 cases (57.1%), occurring during transfusions with Packed Red Cells (PRC). The majority of acute transfusion reactions occurred after the administration of the first blood bag, with 17 cases (48.6%), and these reactions were primarily category I (mild).
Gambaran Morfologi Eritrosit Mahasiswi saat Menstruasi Setiyo Negoro, Muhammad Syamsul Arif; Septilia, Glori
Jaringan Laboratorium Medis Vol. 6 No. 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.9926

Abstract

College students when entering the early adult phase have experienced puberty which is marked by menstruation. The duration of menstruation between one woman and another varies greatly so that the volume of blood released also varies. Excessive blood loss can reduce iron (Fe) levels in the body of female students and can affect erythrocyte morphology. Researchers conducted this study with the aim of knowing the description of erythrocyte morphology of female college students during menstruation. The research conducted is included in the type of descriptive research with observational design. The population was d3 TLM class 12 students with a sample size of 20 students who were experiencing menstruation. The sampling technique used incidental sampling. The results described the morphology of erythrocytes in female students of DIII Medical Laboratory Technology Batch XII Poltekkes Kemenkes Semarang during menstruation on the 4th day based on aspects of assessment of erythrocyte size, namely 7 people (35%) included in the microcytic category and 13 people (65%) included in the normocytic category. Based on the aspect of erythrocyte staining, 7 people (35%) were included in the hypochromic category and 13 people (65%) were included in the normochromic category. While based on the aspect of assessing the shape of erythrocytes, all 20 respondents (100%) were included in the mild poikilocytosis category. The conclusion that can be drawn from this study is the picture of erythrocyte morphology of DIII Medical Laboratory Technology Batch XII Poltekkes Kemenkes Semarang students during menstruation on the 4th day, out of 20 respondents as many as 7 people (35%) showed hypochromic microcytic erythrocyte morphological abnormalities with mild poikilocytosis and 13 people (65%) showed normocytic normochromic erythrocyte morphological abnormalities with mild poikilocytosis. It is recommended to increase the consumption of vegetables and foods that increase the formation of red blood cells during menstruation.
Analisis Jumlah Trombosit Dan Leukosit Pada Pasien Dengue Hemorrhagic Fever (DHF) Di Rumah Sakit Umum Daerah Kabupaten Barru Widarti, Widarti; Kalma, Kalma; Herman, Herman; Ramadhani, Andi Fitria
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9964

Abstract

Dengue hemorrhagic fever (DHF) is a chronic fever disease caused by infection with the dengue virus which is transmitted through the bite of the Aedes aegypti and Aedes albopictus mosquitoes. Laboratory abnormalities that are often found in DHF patients are thrombocytopenia and leukopenia. This study aims to determine the results of examination of platelet and leukocyte counts in dengue hemorrhagic fever (DHF) patients. This study used a descriptive design with the population being all dengue hemorrhagic fever (DHF) patients at the Barru District General Hospital. The sample consisted of 30 DHF patients whose platelet and leukocyte counts were checked using a hematology analyzer for 3 consecutive days of hospitalization. The sampling technique in this research is the purposive sampling method. The results of the study showed that there were 30 DHF patients consisting of 14 (47%) men and 16 (53%) women with the highest age found `DHF being 8 - 12 years old, 10 people (33.33%). On the first day of hospitalization, 29 people experienced thrombocytopenia and 1 person had normal platelets. On the second day of hospitalization, 25 people experienced thrombocytopenia and 5 people had normal platelets. On the third day of hospitalization, 11 people experienced thrombocytopenia and 19 people had normal platelets. On the first day of hospitalization, 17 people experienced leukopenia, 11 people had normal leukocytes and 2 people had leukocytosis. On the second day of hospitalization, 8 people experienced leukopenia and 22 people had normal leukocytes. On the third day of hospitalization, 3 people experienced leukopenia and 27 people had normal leukocytes. This study shows that the majority of DHF patients experience thrombocytopenia while the platelet count tends to be normal.

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