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Jurnal Riset Kefarmasian Indonesia
Published by Asosiasi Pendidikan Diploma Farmasi Indonesia
ISSN : 2656131x     EISSN : 26558289     DOI : https://doi.org/10.33759/jrki
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
JURNAL RISET KEFARMASIAN INDONESIA adalah jurnal yang diterbitkan online dan diterbitkan dalam bentuk cetak. Jurnal ini diterbitkan 3 kali dalam 1 tahun (Januari, Mei dan September) Jurnal ini diterbitkan oleh APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) Lingkup jurnal ini mencakup Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Organik Bahan Alami, Biokimia, Analisis Kimia, Kimia Fisik, Biologi, Mikrobiologi, Kultur Jaringan, Botani dan hewan yang terkait dengan produk farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Nutrisi dan Kesehatan Masyarakat.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 121 Documents
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POLA PERESEPAN ANTIBIOTIK PROFILAKSIS PRE BEDAH SECTIO CAESAREA DI RUMAH SAKIT Saleh, Chusun; Kurniasari, Maya
Jurnal Riset Kefarmasian Indonesia Vol 3 No 1 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i1.117

Abstract

Caesarean section is a surgery to give birth to a child through surgery on the abdominal wall and uterus. Prophylactic antibiotics are preventive antibiotics in Sectio Caesarean surgery. This study aims to determine the pattern of prescribing prophylactic antibiotics in preoperative caesarean section patients which are grouped into 4 specific objectives, namely: patient characteristics such as (age, parity status, payment status), antibiotic class, type of antibiotic, and to determine surgical wound indication ILO, This study used a descriptive method by retrospectively taking data by looking at the prescription (e-prescription), patient medical record data and SOAP (Subjective, Objective, Assessment, Planning). The results showed that out of 300 patients who were parturient, 52 patients (17.3%) had normal delivery and 248 patients with caesarean delivery (82.7%). Most of the ages were between 20-30 years as many as 123 patients (49.6%) and aged > 30-40 years as many as 120 patients (48.38%). As for the status of the most payments in cash, namely 176 patients (71%). The most frequently used antibiotic class is the Cephalosporin group, namely 246 patients (99.6%), the most commonly used type of antibiotic is Ceftriaxon, which is 175 patients (70.6%). The study on Surgical Wound Infection was found in only 1 patient (0,4%) with the antibiotic Ceftriaxon.
UJI KANDUNGAN TIMBAL (Pb) PADA GORENGAN YANG DIJUAL DI PINGGIR JALAN SEPANJANG PANTAI GANDORIAH PARIAMAN SECARA SPEKTROFOTOMETRI SERAPAN ATOM Yulia, Mega; Syahrianti, Dani; Yulis, Rahma
Jurnal Riset Kefarmasian Indonesia Vol 3 No 1 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i1.118

Abstract

Lead is one of the heavy metal elements found in the air pollution which is produced together with motor vehicle fumes. Lead can cause various disorders in human body such as anemia, neurological damage, deformities and body functions, dental caries, impaired kidney function, effects on the heart and infertility. Lead can enter the human body through inhaled air, through the skin and ingested with food. The purpose of this study was to determine the lead content in fried foods (fried sala, fried crab, fried shrimp and fried fish) sale around of Gandoriah Beach, Pariaman. This research was conducted at Baristand Laboratory (Research and Standarirdization Industry Center) Padang from February until March 2020. This study was conducted on 4 samples taken randomly from the total population. The instrument used was atomic absorption spectrophotometry (AAS). The results of 4 samples showed that the lead content in fried sala was 0.1618 mg/kg, with a maximum SNI limit is 0.3 mg/kg, fried crab was 0.4025 mg/kg with a maximum SNI limit is 0,5 mg/kg, fried shrimp was 0.4377 mg/kg with a maximum SNI limit is 0.5 mg/kg, fried fish was 0.2331 mg/kg with an SNI maximum limit is 0.3 mg/kg. Based on the results of this study, it can be concluded all samples contain lead but the level is still below of maximum limit of SNI 7387-2009.
OPTIMASI CAMPURAN AVICEL PH 101 DAN LAKTOSA SEBAGAI BAHAN PENGISI PADA TABLET EKSTRAK BUNGA ROSELLA (Hibiscus sabdariffa L.) SECARA GRANULASI BASAH Kokafrinsia, Zila Tjhia; Saryanti, Dwi
Jurnal Riset Kefarmasian Indonesia Vol 3 No 2 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i2.124

Abstract

Rosella flower (Hibiscuss sabdariffa L.) in traditional medicine can provide protection against various diseases, such as coronary heart disease, cancer, lowering cholesterol, and liver disorders. This study aims to obtain the optimum formula of tablet of rosella flower extract with a mixture of Avicel PH 101 and lactose as a filler using wet granulation method. Rosella flower extract was obtained by maceration of rosella flower powder using 70% ethanol. The optimization formula for tablets using the Simplex Lattice Design method with Design Expert software version 10. The parameters used in the optimization are weight variation, hardness, friability and disintegration time. Verification of the optimal formula using the SPSS 18 program with the One Sample T-test method with a confidence level of 95%. The results showed that the optimal formula of tablet of rosella flower extract was the Avicel PH 101 97.82%: 2.17% lactose. The optimal formula has weight variation 1.53% ± 0.0073; hardness 5.087 kg ± 0.5135; the friability is 0.3% ± 0.041. The resulting disintegration was 22.99 minutes ± 2.218. The results of the verification of the optimal formula show that there is no significant difference between the predictions of the Simplex Lattice Design method and the results of the tests performed so that it can be said that the method is valid.
IDENTIFIKASI BORAKS PADA PENTOL BAKSO YANG DI KELURAHAN AIR HITAM DENGAN PEREAKSI KULIT BUAH NAGA MERAH (Hylocereus polyhizus) Lestari, Dwi; Dewi, Mutia; Ningsih, Suci Cahya; Hidayati, Hidayati
Jurnal Riset Kefarmasian Indonesia Vol 3 No 1 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i1.125

Abstract

Borax is often misused to preserve various foods such as wet noodles, meatballs, rice cake, rhombus and so on. Red dragon fruit skin contains secondary metabolites, namely anthocyanin, anthocyanin is the most important and widespread dye in the skin of red dragon fruit, but the use of red dragon fruit peels has not been studied much naturally. The purpose of this study was to identify borax on the meatball sold in the Air Hitam district with the red dragon fruit skin reagent (Hylocereus polyhizus). This research is experimental with data collection techniques by accidental sampling. In this study used several samples of meatball pentol purchased at the meatball merchant located in Air Hitam Village by using dragon fruit peel and AgNO3 reagent as a comparison indicator. This research includes plant determination, sample collection, sample preparation, spike making, dragon fruit skin extract reagents and qualitative sample testing. Data analysis using descriptive analysis method. The results of the identification of borax on 5 meatball samples using color reagents from the extract (essence) of the red dragon fruit peel and AgNO3 reagent as a comparative indicator showed that all samples of the meatball obtained Negative results
UJI IN VIVO TAHAP PREKLINIS TERHADAP EKSTRAK BATANG PISANG (Musa paradisiaca L.) SEBAGAI ANTIINFLAMASI TOPIKAL Dewi, Ni Luh Kade Arman Anita; Yuda, Putu Era Sandhi Kusuma; Suarnata, I Gede Agus; Sasadara, Maria Malida Vernandes
Jurnal Riset Kefarmasian Indonesia Vol 3 No 2 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i2.129

Abstract

Inflammation is a normal protective response to tissue injury caused by physical trauma, chemical damage, or microbiological substances. Banana stems (Musa paradisiaca L.) have been empirically believed for their topical anti-inflammatory properties. The purpose of this study was to scientifically evaluate the in vivo preclinical anti-inflammatory activity of banana stems. This research was designed experimentally using twenty-five albino male rats which were divided into five groups: the positive control group which received sodium diclofenac gel, the negative control group which received gel basis preparation without any active ingredient, and three experimental groups which received banana stem extract gel in three different concentrations, 5%, 10%, and 15%. Every five rats of every group were firstly injected with 1% of carrageenan, and the anti-inflammatory effect was evaluated every hour for 4 hours using a plethysmometer. The collected data were statistically evaluated. The results showed that banana stem extract gel with concentrations of 15% produced the best anti-inflammatory effect, compared to other gel concentrations. In conclusion, the preparation of 15% banana stem extract gel can be applied as potential topical anti-inflammatory preparation.
ISOLASI SENYAWA AKTIF DAN UJI AKTIVITAS EKSTRAK JAHE MERAH (ZINGIBER OFFICINALE) SEBAGAI IMUNOMODULATOR Masniah, Masniah; Rezi, Jafril; Faisal, Ahmad Purnawarman
Jurnal Riset Kefarmasian Indonesia Vol 3 No 2 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i2.131

Abstract

Red ginger (Zingiber officinale) contains many chemical compounds that have many activities. This study aims to determine the active compounds of Zingiber officinale and immunomodulatory activity that can increase the phagocytosis of macrophage cells and lymphocyte cell proliferation. Red ginger extract compounds were identified using GC-MS. The parameters of immunostimulatory activity were macrophage phagocytosis and lymphocyte proliferation, the preparations were made in several extract concentrations. This research is an experimental study in the laboratory. The research included fresh red ginger, made into ethanol extract, dried. The results were made a suspension, the extract was then given to macrophage cells (phagocytosis testing) and lymphocyte cells (proliferation testing) in vitro to test the immunomodulatory effect. The results showed that the most active extract in macrophage phagocytosis activity was the extract concentration of 500 ppm. While the activity of lymphocyte proliferation was shown by the concentration of group A (Cell, 500 ppm extract, MK, Engerik). The active compound contained in the ethanol extract of red ginger is thought to be Geraniol
PENGENDALIAN PENGELOLAAN OBAT DI INSTALASI FARMASI SUATU RUMAH SAKIT SWASTA KOTA BANDUNG Lisni, Ida; Samosir, Herman; Mandalas, Ester
Jurnal Riset Kefarmasian Indonesia Vol 3 No 2 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i2.134

Abstract

Drug management is a series of planning, procurement, storage, distribution, and control activities carried out by a hospital pharmacy so that drug availability can be guaranteed in sufficient quantities, in its implementation requires a large number of funds. The study was conducted to evaluate drug management in private hospital pharmacies in the city of Bandung using predetermined standard indicators. This study used a retrospective non-experimental observational method. The data collected is in the form of planning data and drug procurement, drug use, drug stock cards, stock-taking reports. The results showed that the achievement of drug planning (107.53%), the frequency of purchase for the low category (34.70%), the medium category was 41.08% and the high category (24.22%), expired drugs (0.085%) and the dead stock (3.81%).
PENGARUH KOMUNIKASI TENAGA FARMASI DALAM UPAYA PENINGKATAN PEMAHAMAN LANSIA TERHADAP DAGUSIBU OBAT (DAPATKAN, GUNAKAN, SIMPAN, BUANG) DI DESA KOPEN KABUPATEN BOYOLALI Anisawati, Amanda; Isma, Faizatul; Tansa, Ilham La; Hanifah, Rafidah; Diana, Rizky Nur; Santoso, Aris Prio Agus
Jurnal Riset Kefarmasian Indonesia Vol 3 No 2 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i2.135

Abstract

Irrational use of drugs and their abusers is a problem that is often found in society. Based on the survey data obtained, there are still residents who get drugs freely without monitoring medical and pharmaceutical personnel or the drugs purchased are medicines from grocery stores, and many residents in Kopen village, Boyolali, do not know how to use appropriate drugs and how to store them. The correct medicine and many of them are still throwing away liquid medicine in the package and without paying attention to damage the medicine package. Education about the drug Dagusibu is one of the efforts we do as pharmaceutical personnel to prevent irrational drug use and to prevent drug abuse by the community, especially the elderly in Kopen Village, Boyolali. The method used is a preventive intervention method and a quantitative approach to the elderly using the Dagusibu questionnaire that we created. Based on filling out the questionnaire before we do the socilization, it was found that 73% of the elderly who do not understand, 18% of the elderly who have little understanding and 7% of the elderly who are accompanied by a guardian who already understands. The understanding of Dagusibu drugs by the elderly in the Village Kopen, Boyolali categorized't get it. It needs to be held socialization to improve the understanding of the elderly and also residents in the Village kopen, Boyolali. After socialization, the obtained results of the questionnaire 27% still do not understand, 64% already understand and also 9% are elderly, accompanied by a guardian in the use of the drug. The conclusion of this research is the role of pharmaceutical personnel hold a very important role in conveying information and education in an improved understanding of the elderly and residents in the Village kopen, Boyolali..
GAMBARAN PERSEDIAAN OBAT DI APOTEK NIAS MEDIKA DENGAN ANALISIS ABC BERDASARKAN RESEP MASUK PERIODE JANUARI-MEI 2020 Nofrika, Vonny; Agustina, Ika; Priyanti, Risca
Jurnal Riset Kefarmasian Indonesia Vol 3 No 2 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i2.140

Abstract

Pharmacy is a pharmaceutical service facility where pharmacy practices are carried out by pharmacists, namely manufacturing including quality control of pharmaceutical preparations, security, procurement, storage and distribution or distribution of drugs, drug management, prescription drug services, drug information services, and drug development services, drug ingredients and traditional medicine One of the scopes in the management of health services is logistics management, which is a field of management whose specific task is to deal with logistics. Pharmacy nias medika there was no specific arrangement for the procurement of drugs with certain methods so that often there is a vacuum of medicine one of which is for drugs contained in a doctor's prescription that goes to the nias medika pharmacy. For this reason, it was necessary to control drug inventory using certain methods, one of which was by using ABC analysis. The type of research was descriptive and quantitative, based on the prescription entry by recording the name of the drug, the number of drugs, and the unit price of the drug and then processed using data analysis during January-May 2020. The results showed that there were 160 types of drugs based on prescription entry into the drugstore nias medika. With 32 types (20% ) drugs classified as group A with an investment value of 69.68% with laroton drugs which are in the highest position 47 types (29.37%) drugs classified as group B with an investment value of 20.25%, while 81 types (50, 63%) the drugs belong to group C with a total investment of 10.07%.
GAMBARAN PENGGUNAAN TERAPI GEA (GASTROENTERITIS ) PADA PASIEN ANAK DI RSUD BATARA SIANG PANGKEP SULSEL Wahyuni, Dwi Fitrah; Riska, Riska
Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i3.137

Abstract

GEA (Gastroenteritis) or diarrhea is a disease caused by digestive tract disorders that are infected by bacteria. Treatment of early diarrhea, especially the choice of initial therapy, greatly affects the success of providing appropriate and appropriate therapy. This study aims to determine the rationality of therapy in pediatric patients at Batara Siang Pangkep Regional Hospital, South Sulawesi City. This study is a non-experimental study with a retrospective descriptive evaluation study using patient medical records. The samples that met the inclusion criteria were 65 patients. Acute diarrhea was mostly found in men as many as 38 patients (58%) while for women as many as 27 patients (42%). Characteristics of age 1-3 years (82%). The result showed that there are 3 therapeutic regimen in pediatric patient namely cotrimoxazole,electrolit, and zinc. So from these data meet the standards of management of diarrheal disease in children.

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