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Jurnal Riset Kefarmasian Indonesia
Published by Asosiasi Pendidikan Diploma Farmasi Indonesia
ISSN : 2656131x     EISSN : 26558289     DOI : https://doi.org/10.33759/jrki
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
JURNAL RISET KEFARMASIAN INDONESIA adalah jurnal yang diterbitkan online dan diterbitkan dalam bentuk cetak. Jurnal ini diterbitkan 3 kali dalam 1 tahun (Januari, Mei dan September) Jurnal ini diterbitkan oleh APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) Lingkup jurnal ini mencakup Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Organik Bahan Alami, Biokimia, Analisis Kimia, Kimia Fisik, Biologi, Mikrobiologi, Kultur Jaringan, Botani dan hewan yang terkait dengan produk farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Nutrisi dan Kesehatan Masyarakat.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 228 Documents
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HUBUNGAN PENGETAHUAN DIABETES MELITUS DAN PENGETAHUAN ASUPAN GIZI PADA REMAJA DI SMK X SIDOARJO Aristia, Bella Fevi; P, Aulia Rachma; Intan, Firda; K, Yunita Dyah
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 3 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i3.486

Abstract

The prevalence of diabetes mellitus (DM) in the world and nationally continues to increase. DM generally occurs in the age group >50 years; however, DM currently affects many young age groups. Adolescents affected by DM can continue to increase if they do not have good knowledge about DM and nutritional intake. This study aims to determine the level of DM knowledge and nutritional intake among high school adolescents in SMK X West Sidoarjo. This research method is descriptive-observational with prospective data collection. The research instrument used the DKQ-24 questionnaire and a valid nutritional intake questionnaire. The selected sample is in accordance with the research inclusion criteria, totaling 50 people The results showed that 76% did not know the causes of DM and diet rules; 78% people also did not know the importance of DM treatment to control blood sugar. Regarding knowledge of nutritional intake, most respondents (56%) did not know the calculation and value of BMI, 46% did not know the importance of fiber for controlling blood sugar, and 40% did not know the types of foods with a high glycemic index. The majority of respondents have good knowledge about diabetes (76%) and nutritional intake (70%). Chi-square analysis shows that there is a relationship between knowledge of DM and knowledge of nutritional intake, with a p value of 0.027. DM knowledge and nutritional intake are important to shape healthy lifestyle behaviors in an effort to prevent DM in adolescents
PERBANDINGAN SIFAT FISIK SEDIAAN LILIN AROMATERAPI KOPI ROBUSTA (Coffea canephora) DAN KOPI ARABIKA (Coffea arabica) Kurniasih, Trifonia Rosa; Sari, Dian Purwita; Maeshofa, Irna; Anggraini, Cristine; Harefa, Rai Madra Somasi; Sitompul, Lian Melissa
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.487

Abstract

Coffee is a plant that has benefits that can reduce stress when applied to aromatherapy candles. There are two most popular types of coffee: robusta coffee (Coffea canephora), which has a more intense taste and aroma, and arabica coffee (Coffea arabica), which has a lighter taste and aroma. This research aimed to compare the physical properties of robusta coffee (FR) and arabica coffee (FA) aromatherapy candle preparations. The formulation of aromatherapy candle preparations had a paraffin base (10%), stearin, and composition of coffee oil and coffee powder, 2% and 2.5% for formula 1 and 10% and 10% for formula 2. Organoleptically, the candle was solid, not cracked, and had the color brown to black. The aroma of formula 1 was weak, and the aroma of formula 2 was strong, typical of coffee aroma. The burning time for candles with an average weight of 8.52 grams for each group for formulas 1 and 2 FA was 11.45 minutes and 10.04 minutes, while FR was 11.57 minutes and 9.57 minutes. The melting point for aromatherapy candles was an average of 52–54 °C. This value meets the criteria for candle preparations based on SNI. A comparison of the formulas for aromatherapy candle preparations had a significant effect on the weight and burning time of aromatherapy candle preparations. Overall, the coffee candle aromatherapy meets the SNI criteria for candle preparations.
PROFIL PENGOBATAN KEMOTERAPI PADA PASIEN KANKER PAYUDARA DI RUMAH SAKIT UMUM DAERAH KOTA BOGOR PADA TAHUN 2022 Anjani Dwi Cahya; Halimatushadyah, Ernie; sari, Dwi Puspita; Ekasari, Dian
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 3 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i3.491

Abstract

            Breast cancer is cancer that starts in the breast tissue, which consists of milk-producing glands (lobules) and ducts that connect the lobules to the nipple. One of the efforts to reduce the morbidity rate of breast cancer is chemotherapy. Chemotherapy involves the use of cytostatic drugs aimed at stopping the growth and spread of cancer cells. The purpose of this study was to determine the pattern of drug use and evaluation of drug use in breast cancer patients. The study was conducted observational with retrospective data collection. The research was conducted from May to June 2023. The number of samples was 96 samples with the method of purposive sampling technique using the slovin formula, the data were analyzed qualitatively. The results of the chemotherapy treatment profile using single therapy 9 patients (9.38%), combination therapy 87 patients (90.63%) with a combination chemotherapy regimen of Epirubicin and Cyclophosphamide followed by Paclitaxel as many as 50 patients (57.47%). Evaluation of appropriate patient (98.96%), appropriate indication (100%), appropriate drug (100%), appropriate dose (19.79%), inappropriate dose (20.83%), under dose (34.48%), over dose (25%).
PENERAPAN CUSTOMER SATISFACTION INDEX (CSI) DAN ANALISIS GAP PADA KUALITAS PELAYANAN KEFARMASIAN DI APOTEK SEHAT BERSAMA 2 JAKARTA TIMUR Brahmono, Angga; Susanto, Yugo; Widiyanto, Rahmat; Erzania, Reyfana
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.502

Abstract

Health quality assurance is a very important and fundamental approach or effort in providing health services. One form of service quality in the health service sector is pharmaceutical services in pharmacies. Satisfaction is an important part of pharmaceutical services because it is useful for improving medical health service outcomes. The aim of this research is to analyze customer satisfaction and expectations regarding the performance of pharmaceutical services at Apotek Sehat Bersama 2. The methods used in this research are the Customer Satisfaction Index (CSI) method and Gap Analysis. This research method is a survey, namely by distributing questionnaires to pharmacy customers. The sampling technique was carried out by accidental sampling with 188 respondents. The scale used is a Likert scale based on the level of satisfaction and expectations. The research results show that the Customer Satisfaction Index (CSI) value for customer satisfaction level is 82.4%, which is included in the very satisfied criteria. The highest gap value is an indicator that pharmacy staff understand customer complaints, provide drug/health information clearly and easily understood, always provide information on how to use drugs requested by customers, pharmacy staff are always polite and friendly in providing service to customers and pharmacy staff provide information on usage rules. drugs and side effects that may arise as well as the lowest gap value is that the drug requested by the customer is always available.
PENGARUH PROPILENGLIKOL TERHADAP FORMULASI DAN KARAKTERISTIK FISIK SEDIAAN PATCH EKSTRAK ETANOL DAUN INGGU (Ruta angustifolia L. Pers) Hikma, Nurul; Yassir, Budiman; Khairi, Nur; Marwati, Marwati; Pattinggi, Patricia
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759//jrki.v6i2.507

Abstract

Ruta angustifolia L.Pers contain essential oil, steroids, flavonoids, tannins, quinones, and saponins compounds which have the potential to act as analgesics. This research aimed to determine the effect of varying propylene glycol concentrations on the physical characteristics of patches using the solvent evaporation method. Patch preparations were made in 3 formulas with variations of propylene glycol, namely F1 (without propylene glycol), F2 (10%), F3 (20%), and F3 (30%), and the patch was evaluated. The results of the physical characteristics obtained were patches with a yellowish green color, typical extract smell, round shape, thin film, smooth, dry, and elastic with a folding resistance of >200 times, thickness ranging from 0.02-0.03 mm, weight uniformity meeting the requirements, namely CV value 5%, %drying loss <9.20%, humidity of each formula <9.79% with a pH of around 7. Thus, it can be concluded that the ethanol extract of inggu leaves influences the uniformity of the weight and thickness of the patch.
AKTIVITAS SABUN PADAT EKSTRAK KULIT BUAH APEL (Malus Domestica) TERHADAP Staphylococcus aureus Zuniarto, Ahmad Azrul; pandanwangi, Siti; Nopitasari, Sindi; Khalifah, Tria Incky
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.508

Abstract

        Soap is a type of skin cleansing agent, suitable for removing various types of dirt and bacteria on the skin. Apple peel waste contains more active ingredients than the fruit. The aim was to determine the antibacterial activity of apple bark (Malus domestica) soap extract against Staphylococcus aureus and determine the optimal concentration to inhibit bacterial growth. The research method used uses laboratory experimental research methods. The measurement method is the diffusion test. This research includes collecting plant materials, making simplicia, making extracts, phytochemical screening, making bar soap, formulating evaluation testing, and testing bar soap formulations from apple peel extract (Malus domestica) against Staphylococcus aureus. The soap resulting from leather waste extraction consists of concentrations of 15%, 20% and 25%, basic ingredients for soap, bar soap and disinfectant soap brand there is no real difference. These results indicate that bar soap containing apple peel extract (Malus domestica) at a concentration of 25% is most effective against Staphylococcus aureus. The conclusion of this study shows that bar soap containing apple peel extract (Malus domestica) has antibacterial activity against Staphylococcus aureus.
ANALISIS EFEKTIVITAS BIAYA BEBERAPA MOISTURIZER Dasopang, Eva Sartika; Hasanah, Fenny; Siahaan, Desy Natalia; Salsabila, Putri
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 1 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i1.512

Abstract

The growth of e-commerce continues to increase in Indonesia, one of which is the Shopee application which can buy goods, sell various kinds of products, and shop safely. Shopee showed in early 2020 that the beauty category ranked highest in the best-selling product categories, one of which was Moisturizer. The purpose of this study was to determine the comparison of each moisturizer which is more cost effective. This type of research uses a true experimental method with a posttest only control group design to determine the before and after conditions between the control group (no moisturizer) and the experimental group (moisturizer X, moisturizer Y, moisturizer Z). The sample of this study consisted of 20 volunteers with observations carried out for 4 weeks to obtain the effectiveness of moisture recovery, pores, blemishes, wrinkles. The results showed that moisturizer Z for moisture is more cost effective with an ACER value of Rp. 859 ICER Rp. 886. While moisturizer Y for pores is more cost effective with an ACER value of Rp. 2,515 ICER Rp. 2,800. While moisturizer Y for blemishes is more cost effective with an ACER value of Rp. 2,427.7 ICER Rp. 2,581. Then moisturizer Z for wrinkles is more cost effective with an ACER value of Rp. 1,846 ICER Rp. 2,307. In conclusion, moisturiser C is the most cost effective for moisture and wrinkles while moisturiser B is more cost effective for pores and blemishes.
PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK DAUN Litsea elliptica Blume Chandra, Pra Panca Bayu; Handayani, Indri Astuti
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.513

Abstract

Kalimantan Island is an area with forests that can be developed for potential results, especially in plants with medicinal properties for health. The medicinal properties of plants are the role of the secondary metabolites contained in them. One of them is Litsea, a plant that comes from the Lauraceae family with 45 genera and more than 2,000 species. Plants from this genus are widely used by the community as traditional medicine, especially Litsea elliptica. One of the secondary metabolite contents of Litsea elliptica is flavonoids. The aim of this research was to determine the flavonoid content of Litsea elliptica leaf extract. The extraction process was carried out by maceration with 96% ethanol solvent. The results of the maceration extraction are then carried out by evaporation until a thick extract is obtained. The total flavonoid content was determined using the Colorimetric-Aluminum Chloride Method with a UV-Vis spectrophotometric instrument, resulting in a total flavonoid content of Litsea elliptica leaf extract of 391.01 mg ± 0.27 mg. The conclusion of this research is that Litsea elliptica leaf extract has a flavonoid content of 0.39%
PENGARUH VARIASI BASIS TERHADAP DAYA SIMPAN SALEP YANG MENGANDUNG  EKSTRAK ETANOL DAUN BELIMBING WULUH (Averhoa bilimbi (L)) Lestari, Tri Puji; Kurniawati, Evi; Widyaningrum, Esti Ambar
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.519

Abstract

            Starfruit wuluh, scientifically known as Averrhoa blimbi L., contains secondary metabolites such as flavonoids and tannins, which function as antibacterial agents. The extract of starfruit wuluh leaves is formulated into a ointment for easy application. The selection of a suitable ointment base is crucial to achieve the formulation's effectiveness. Understanding the influence of using different bases, specifically oil-in-water emulsion base and water-soluble ointment base, on the stability of ointment containing ethanol extract of starfruit wuluh leaves is the aim of this research. Stability testing is conducted for two weeks at room temperature. Physicochemical tests include organoleptic evaluation, homogeneity, adhesiveness, pH, and spreading ability of the formulation. The results indicate that the variation in the type of base does not affect organoleptic aspects, homogeneity, and pH during storage but does impact adhesiveness and spreading ability of the ointment containing starfruit wuluh leaf extract during storage
PERBEDAAN KADAR TANIN TOTAL EKSTRAK DAUN TURI (Sesbania grandiflora L.) VARIETAS MERAH DAN PUTIH DENGAN METODE SPEKTROFOTOMETRI UV-VIS Kurniawati, Evi; Lestari, Tri Puji; Hardini, Pri Hardini
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.520

Abstract

Turi is one of the plants that has activity as an antimicrobial, antifungal, anti-inflammatory and antioxidant. The content of secondary metabolites in turi leaves are flavonoids, tannins, and alkaloids. Tannins are phenol compounds with hydroxy groups and several other groups such as carboxyl. This study aims to determine the difference in total tannin levels in turi leaf extracts of red and white varieties. The extraction process with maceration using 70% ethanol solvent. Then the extract obtained was carried out screening tests, thin layer chromatography tests, and determination of tannin levels by UV-Vis spectrophotometry. Parameters of analytical method validation were carried out by determining linearity, accuracy, precision, LOD and LOQ. The results of the validation of the linearity analysis method obtained a linear regression equation y = 0.0038x + 0.3153 r value = 0.9985. The accuracy results obtained are in the range of 97-103%, RSD value of 0.18% and the LOD value is 6,213 ppm and LOQ is 20,711 ppm. The measurement results of total tannin content in turi leaf extracts of red and white varieties at a wavelength of 750 nm are 7.876% w / w TAE and 9.195% w / w TAE, respectively. Independent sample T-test results show there is a significant difference (p < 0.05) in the total tannin content of turi leaf extracts of red and white varieties. Keywords: Turi leaves, tannin, UV-vis spectrophotometer

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