Jurnal Riset Kefarmasian Indonesia
JURNAL RISET KEFARMASIAN INDONESIA adalah jurnal yang diterbitkan online dan diterbitkan dalam bentuk cetak. Jurnal ini diterbitkan 3 kali dalam 1 tahun (Januari, Mei dan September)
Jurnal ini diterbitkan oleh APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)
Lingkup jurnal ini mencakup Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Organik Bahan Alami, Biokimia, Analisis Kimia, Kimia Fisik, Biologi, Mikrobiologi, Kultur Jaringan, Botani dan hewan yang terkait dengan produk farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Nutrisi dan Kesehatan Masyarakat.
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<![CDATA[PENGARUH TERAPI FARMAKOLOGI DAN NON-FARMAKOLOGI TERHADAP PENURUNAN NYERI MENSTRUASI PADA MAHASISWI FAKULTAS FARMASI UNIVERSITAS BHAKTI KENCANA BANDUNG ]]>
<![CDATA[Anggriani, Ani]]>;
<![CDATA[Mulyani, Yani]]>;
<![CDATA[Pratiwi, Lili Dinda]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v3i3.156
<![CDATA[Menstrual pain is a problem that women often complain about in their teens. Menstrual pain (dysmenorrhea) is pain before or during menstruation in the lower abdomen due to uterine cramps. The prevalence of dysmenorrhea in Indonesia is 54% primary dysmenorrhea and 9% secondary dysmenorrhea. Due to the severe pain that is felt during menstruation, 10% of teenage girls are absent from school and work for 3 days each month. This study aims to determine the effect of pharmacological & non-pharmacological therapy on reducing menstrual pain in adolescents. This research is an experimental research with one group pretest-post test design. The research sample used purposive sampling method, with a sample of 76 respondents. Data were analyzed using the Wilcoxon Signed Rank Test & chi-square test. The results showed that the Wilcoxon test with the results of Sig. 0.000<0.05, meaning that there is a difference in the intensity of menstrual pain before & after therapy. So it can be concluded that there is an effect of pharmacological and non-pharmacological therapy on decreasing the intensity of menstrual pain. For the relationship of non-pharmacological therapy Chi-Square test results have a value of Sig. 0.514>0.05, meaning that there is no significant relationship to the intensity of menstrual pain. For the relationship between pharmacological therapy, the results of Sig. 0.019<0.05, meaning that there is a significant relationship with the intensity of menstrual pain in adolescent girls at Bhakti Kencana University, Bandung.]]>
<![CDATA[PENGARUH PENAMBAHAN POLIETILEN GLIKOL 6000 PADA TABLET IBUPROFEN DISPERSI PADAT TERHADAP ABSORBSI IBUPROFEN SECARA IN SITU ]]>
<![CDATA[Tampubolon, Antetti]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v3i3.167
<![CDATA[Drug absorption can be decided by various methods, namely in vitro methods, in situ methods, and in vivo methods. The in situ method is a procedure that is very close to the in vivo method. The aim of this study was to identify the effect of accumulation of polyethylene glycol 6000 (PEG 6000) on solid dispersion of ibuprofen tablets on the in-situ absorption of the drug. This research was conducted through an experiment to determine the effect of adding polyethylene glycol 6000 to the absorption of ibuprofen in situ by flowing the solution from solid dispersion ibuprofen tablets, solutions from generic ibuprofen tablets and standard ibuprofen solutions. The solid dispersion system was carried out by melting ibuprofen and polyethylene glycol 6000 in a ratio of 1:05. The drug solution was flowed through the lumen of the small intestine of male rats. Unabsorbed ibuprofen was measured by an ultraviolet spectrophotometer at a wavelength of 225.5 nm. Next, the absorbed level of ibuprofen was calculated. The results showed that ibuprofen from solid dispersion tablets was absorbed more than ibuprofen from generic tablets and standard ibuprofen. It can be concluded that polyethylene glycol 6000 has an effect on the absorption of ibuprofen in situ.]]>
<![CDATA[UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN MANGGA KASTURI (Mangifera casturi Kosterm.) ]]>
<![CDATA[Lestari, Dwi]]>;
<![CDATA[MA, Muthia Dwi]]>;
<![CDATA[Pratiwi, Jati]]>;
<![CDATA[Saputri, Lidya Handoko]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v3i3.169
<![CDATA[Mangga Kasturi (Mangifera casturi Kosterm.) is one of the plants in Indonesia that has potential as an antioxidant. The purpose of this study was to determine the IC50 value and antioxidant potential of the ethanol extract of mangga kasturi leaves (Mangifera casturi Kosterm.). The ethanol extract of mangga kasturi leaves (Mangifera casturi Kosterm.) was extracted using maceration with 96% ethanol as solvent. The antioxidant activity test was carried out using the DPPH (1,1-Diphenyl-2-Picrylhydrazil) method using a UV-Vis spectrophotometer and vitamin C as a comparison. The results of phytochemical screening tests on ethanol extracts showed positive secondary metabolites such as alkaloids, flavonoids, tannins, and quinones. Testing the ethanol extract of Mangga Kasturi leaves (Mangifera casturi Kosterm.) with the DPPH method showed that the ethanol extract had an antioxidant activity with an IC50 value of 83.61 ppm in the strong category of antioxidant potential.]]>
<![CDATA[LAJU FILTRASI GLOMERULUS PASIEN DIABETES MELITUS TIPE II DI SALAH SATU RUMAH SAKIT SWASTA DI KABUPATEN DEMAK ]]>
<![CDATA[Rukminingsih, Fef]]>;
<![CDATA[Widiastuti, Mei]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v3i3.179
<![CDATA[Diabetes Mellitus (DM) Type II is a group of metabolic diseases with hyperglycemia characteristics. The use of oral hypoglycemic drugs (OHO) lasts for a relatively long time. Most of the OHO is excreted through the kidneys. This study aims to determine the Glomerulus Filtration Rate (GFR) of type 2 DM patients who use OHO at the "X" Hospital, District of Demak. This study is an observational descriptive study using retrospective data obtained from medical record data (RM) of outpatient JKN participants with type 2 DM for the period October-December 2020. Inclusion criteria were patients who received OHO for at least one year with or without comorbidities, aged 36-65 years, and had a serum creatinine test. Patients receiving combination therapy with insulin were excluded. LFG is calculated using the Cockroft-Gault formula. From 82 patients, 52 patients (62.2%) were female, 74 patients (90.2%) were more than 45 years old. Patients who consumed OHO for more than 2 years were 47 (57.3%). Patients without comorbidities were 62 (75.7%) people. Patients who experienced a decrease in GFR in the moderate category (stage 3) as many as 24 people (29.3%), a decrease in GFR in the severe category (stage 4) as many as 5 people (6.1%) and 1 person (1.2%) experienced End Stage Renal Disease.]]>
<![CDATA[ANALISIS KANDUNGAN PEMANIS BUATAN SIKLAMAT PADA SIRUP YANG BEREDAR DIPASAR BESAR MALANG SECARA KUANTITATIF MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS ]]>
<![CDATA[Jayadi, Lukky]]>;
<![CDATA[Hernaningsih, Maritha]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v3i3.184
<![CDATA[Sweeteners are chemical compounds that are often added and used for industrial food processing products as well as beverages and foods, sweeteners consist of natural sweeteners and synthetic sweeteners, one of the synthetic sweeteners is sodium cyclamate. This study aims to identify and determine the level of sodium cyclamate in syrup by UV spectrophotometry method and to determine the level of sodium cyclamate in syrup is still safe for consumption. The type of research is experimental and descriptive. The research sample used is syrup which is sold in the big market of Malang City. The method used for the determination of sodium cyclamate levels was done by UV spectrophotometry whose absorption was measured at a maximum wavelength of 314 nm. The results of the quantitative analysis showed that there were positive samples containing sodium cyclamate, namely sample 1, sample 2 and sample 3. The assay results in sample 1 were 238.78 mg/kg, sample 2 was 239.65 mg/kg and sample 3 was 241.39 mg/kg. Of the three samples tested for levels of cyclamate in syrup sold in the big market in Malang City, they still meet the requirements set by the head of the Food and Drug Supervisory Agency.]]>
<![CDATA[AKTIVITAS ANTIOKSIDAN DARI DAUN BINTANGUR (Calophyllum inophyllum L.) TERHADAP RADIKAL BEBAS DPPH (1,1 Difenil-2-pikrihidrazil ]]>
<![CDATA[Faisal, Ahmad Purnawarman]]>;
<![CDATA[Nasution, Pratiwi Rukmana]]>;
<![CDATA[Wakidi, Riza Fahlevi]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v4i1.200
<![CDATA[Antioxidants are compounds that can inhibit oxidation reactions by binding to free radicals and highly reactive molecules. Bintangur contains saponins, tannins, flavonoids and alkaloids. In the presence of flavonoids, the purpose of this study is to understand the antioxidant activity of ethanol extracts against DPPH free radicals, and the IC50 parameter has the highest antioxidant activity. Use ethanol to macerate Bintangur leaf powder. Analyze the content of secondary metabolites in ethanol extracts. Use a spectrophotometer to test the antioxidant activity of the obtained extract against DPPH free radicals at a wavelength of 517 nm, and determine the IC50 value. Routine was used as a positive control in this study. The results of three repeated studies showed that the IC50 values ​​of the ethanol extract were 65.49 ppm, 65.76 ppm, and 65.76 ppm, respectively. Average IC50 value is 55.67 ppm.]]>
<![CDATA[IDENTIFIKASI PARASETAMOL DALAM JAMU PEGAL LINU YANG DIPEROLEH DARI DEPOT JAMU DI KOTA DENPASAR ]]>
<![CDATA[Ni Made, Maharia Ningsih]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v4i1.208
<![CDATA[The use of traditional medicine in the form of herbal medicine is in great demand by the people of Indonesia, one of that is pegal linu herb. Based on PERMENKES No. 006/Menkes/Per/V/2012 articles 33 and 37 states that traditional medicine may not contain medicinal chemical. Medicinal chemical that is often added into herbal medicine for pegal linu herb is paracetamol.This study aims to determine the presence of paracetamol in pegal linu herb depots in Denpasar city. The research method used an exploratory descriptive method and samples of herbal medicine were taken by purposive sampling, 14 samples of herbal medicine of various brands that was sold at depots in Denpasar City. The research was conducted at the chemical laboratory of Bali International University in July 2021. After preparation, the fourteen samples of herbal medicine were identified using Thin Layer Chromatography (TLC) with selection mobile phase ethanol p.a, detection with UV light 254 nm and 0.05 M H2SO4 sprayer. Completeness identification was also carried out descriptive labeling of herbal products containing paracetamol. Positive samples contain paracetamol if the Rf value and spot color are similar to the paracetamol comparison standard. The Rf results obtained that samples with codes F, I, K, and L were 0.68; 0.68; 0.68 and 0.68 which are the similar as the standard Rf for comparison of paracetamol and positive control which is 0.69. The conclusion of the research is that there are various brands of pegal linu herb sold in Indonesia that are suspected to contain 4 brands of paracetamol. Research suggestions for consumers who consume a brand of traditional herbal medicine are expected to be more selective in choosing herbal medicine by first checking the product registration number.]]>
<![CDATA[FORMULASI HARD CANDY DARI SARI BUAH JERUK NIPIS (Citrus aurantifolio), MADU (Mell depuratum) DAN KAYU MANIS (Cinnamomum burmanii) BERDASARKAN PERBEDAAN SIRUP GLUKOSA ]]>
<![CDATA[Yulia, Mega]]>;
<![CDATA[Azra, Fadhilla Putri]]>;
<![CDATA[Ranova, Riki]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v4i1.212
<![CDATA[Lime is a fruit that is widely used by people for treatment cough. For efficiency use of lime, it can processing to product that easier for using such as hard candy. This study aims to determine the results of physical tests and panelists preference for hard candies made from lime juice, honey and cinnamon. The method used is an experimental method by combining lime juice, honey, cinnamon and varying glucose syrup as a candy forming ingredient. Physical evaluation of each formula which includes analysis of water content and ash content, also hedonic test of 3 formulas to 100 panelists. The results of the physical evaluation carried out on the 3 formulas showed that all formulas met the quality requirements of SNI 3547.1:2008 hard candy for water content and ash content, also the results of the hedonic test using non parametric SPSS showed that there was a significant effect on taste and texture where formula III was the most preferred by panelist.]]>
<![CDATA[PERSEPSI MAHASISWA DALAM PEMBELAJARAN DARING PADA MATA KULIAH FARMASI SIMULASI DI MASA PANDEMI COVID-19 ]]>
<![CDATA[Maryanti, Lilis]]>;
<![CDATA[Rulianti, Mona Rahmi]]>;
<![CDATA[Yuliani, Yuliani]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v4i1.214
<![CDATA[This study aims to determine student perceptions of online learning in simulated pharmacy courses during the Covid-19 pandemic. This type of research is descriptive research. Sampling used a purposive sampling technique with clear inclusion criteria, namely students who had received a simulated pharmacy practice course in the fifth semester of the Pharmacy Department of the Health Polytechnic of the Ministry of Health of Palembang as many as 77 students. Questionnaires distributed via google form with a Likert-scale and one essay question. Analysis of the data is used by calculating the percentage of respondents and analyzing each indicator. The research results obtained are good perceptions from students of online learning in simulated pharmacy courses during the Covid-19 pandemic. The score for the percentage of respondents obtained for the teaching and learning process indicators shows good criteria of 72.7%, for lecturers' competence indicators showed good criteria of 79.2%, while for facilities and infrastructure indicators also showed good criteria of 75.1%]]>
<![CDATA[EVALUASI SEDIAAN MASKER GEL PEEL-OFF KOMBINASI EKSTRAK DAUN MANGGA BACANG (Mangifera foetida)DAN DAUN SALAM (Syzygium polyanthum) ]]>
<![CDATA[Putriani, Kony]]>;
<![CDATA[Mardhiyani, Dini]]>;
<![CDATA[Anggraini, Lovera]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v4i1.218
<![CDATA[Mango Bacang leaves and bay leaves are plants that can be used as ingredients in traditional medicine as natural antibacterials which are believed to help get rid of acne. Several previous studies also reported that Bacang mango leaves and bay leaves have activity against Staphylococcus aureus, Escherichia coli and Salmonella typhi bacteria. This study aims to determine the evaluation results of peel-off gel mask preparations that meet the requirements. The test methods include organoleptic test, pH test, viscosity, homogeneity test and dispersion test. The test results showed that F1 and F2 were the best formulas with the characteristics of a green-black gel, a characteristic odor of mango Bacang and bay leaves, a viscosity of 1129 cPs and 1135 cPs, pH 4.4 and 4.5. The dispersion test was 5.1 cm and 5.7 cm and the homogeneity test on the peel off gel mask was homogeneous, there were no fibers, lumps or differences in color when applied to a transparent slide.]]>
