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Jurnal Aisyah : Jurnal Ilmu Kesehatan
Published by Universitas Aisyah Pringsewu
ISSN : 25024825     EISSN : 25029495     DOI : 10.30604/jika
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Jurnal Aisyah: Jurnal Ilmu Kesehatan (JIKA), with registered number ISSN 2502-4825 (Print) and ISSN 2502-9495 (Online), is an international peer-reviewed journal published two times a year (June and December) by Universitas Aisyah Pringsewu (UAP) Lampung. JIKA is intended to be the journal for publishing articles reporting the results of research on Health Science field especially Nursing and Midwifery, as well as with their development through interdisciplinary and multidisciplinary approach. The submission process of the manuscript is open throughout the year. All submitted manuscripts will go through the blind peer review and editorial review before being granted with acceptance for publication.
Arjuna Subject : Keperawatan - Keperawatan (Lain-Lain)
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Management Information Systems in Decision Making: Narrative Review Natalia Kristiani; Kusworo Adi; Apoina Kartini
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 3: September 2021
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (654.33 KB) | DOI: 10.30604/jika.v6i3.989

Abstract

Management has a role in generating information, which requires the use of information systems capable of producing relevant and better data. Systematic decision-making procedures are also needed to produce more focused data. In making decisions for hospital development, hospital management considers several factors, including health programs by looking at facilities and specialist doctors who can provide excellent service, as well as efforts with good numbers and services to introduce or convince the public of our services. general, company, and insurance This research uses a narrative review approach, with many articles on the same problem. Articles are taken from a database from Scopus, Science Direct, ProQuest, SpringerLink, Google Scholar, Nature, JSTOR, and Emerald Insight with a total of 29 articles used. The purpose of this study is to determine whether management has a significant influence in decision making. decisions in hospitals with strategic support systems such as human resource development, program selection, marketing, and facility growth.  Abstrak: Manajemen memiliki peranan dalam menghasilkan informasi, yang mengharuskan penggunaan sistem informasi yang mampu menghasilkan data yang relevan dan lebih baik. Prosedur pengambilan keputusan yang sistematis juga diperlukan untuk menghasilkan data yang lebih terfokus. Dalam mengambil keputusan untuk pengembangan rumah sakit, manajemen rumah sakit mempertimbangkan beberapa faktor, antara lain program kesehatan dengan melihat fasilitas dan dokter spesialis yang dapat memberikan pelayanan prima, serta usaha dengan jumlah dan pelayanan yang baik untuk memperkenalkan atau meyakinkan masyarakat akan pelayanan kami. umum, perusahaan, dan asuransi Penelitian ini menggunakan pendekatan narrative review, dengan banyak artikel tentang masalah yang sama. Artikel diambil dari data base yang berasal dari scopus, science direct, ProQuest, SpringerLink, Google Scholar, Nature, JSTOR, dan Emerald Insight dengan total artikel yang digunakan sebanyak 29. Tujuan dari penelitian ini adalah untuk mengetahui apakah manajemen memiliki pengaruh yang signifikan dalam pengambilan keputusan di rumah sakit dengan sistem pendukung strategis seperti pengembangan sumber daya manusia, pemilihan program, pemasaran, dan pertumbuhan fasilitas.
Identifying Rejection Response of the COVID-19 Vaccination Program in the View of Elderly Community in Palembang Suzanna, Suzanna; Natosba, Jum; Fatriansari, Asih
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (641.384 KB) | DOI: 10.30604/jika.v7i1.823

Abstract

The general public's willingness to be vaccinated against COVID-19 is the first step toward establishing a high vaccination rate and managing the pandemic. However, because some people refuse to take the vaccine, vaccine indecision is one of the greatest barriers to managing a pandemic. The objective of this study is to describe the experience of the elderly refusing to be vaccinated against COVID-19. This research is a qualitative study with an empirical phenomenological approach and uses in-person interviews with the time that has been mutually agreed between researchers and informants. Informants are recruited through purposive sampling with criteria for inclusion of elderly age and do not want to be vaccinated. This study reached saturation when the number of participants reached 6 people.  Data analysis was administered through Haase's adaptation of the Colaizzi method used to analyze the transcribed. Based on the theme formed, the initial theme is the rejection of the presence of vaccination programs, deep doubts about the validity of the vaccine, mistrust about the content and benefits of the vaccine and the determination of the elderly to maintain rejection. The problem of vaccine doubt is influenced by many factors both sourced from internal and external, and modifications are needed to the internal and external factors.  Abstrak: Kesediaan masyarakat umum untuk menerima vaksinasi COVID-19 adalah langkah pertama untuk mencapai tingkat pengambilan vaksinasinasi yang tinggi dan mengendalikan situasi pandemi. Namun, keragu-raguan vaksin merupakan salah satu kendala utama untuk mengendalikan pandemic karena beberapa individu menolak untuk divaksin. Penelitian ini bertujuan untuk menggambarkan pengalaman lansia menolak untuk di vaksinasi COVID-19. Pada penelitian ini menggunakan metode kualitatif dengan pendekatan fenomenologi empiris dan menggunakan wawancara langsung dengan waktu telah disepakati bersama antara peneliti dengan informan. Informan direkrut melalui purposive sampling dengan kriteria inklusi usia lansia dan tidak mau divaksin. Penelitian ini mencapai satu rasi ketika jumlah partisipan mencapai 6 orang. Analisis data dilakukan melalui adaptasi Haase dari metode Colaizzi digunakan untuk menganalisi straskrip. Berdasarkan tema yang terbentuk tema awal yaitu penolakan terhadap kehadiran program vaksinasi, keraguan mendalam terhadap kehalalan vaksin, ketidak percayaan mengenai kandungan dan manfaat vaksin dan keteguhan lansia untuk mempertahankan penolakan. Masalah keraguan vaksin dipengaruhi oleh banyak faktor baik yang bersumber dari internal maupun eksternal, dan diperlukan modifikasi pada faktor internal maupun eksternal tersebut.
The Influence of Pre-Marriage Class on Knowledge of Bride and Groom in Prevention of Stunting Toddlers Sumardilah, Dewi Sri; Astuti, Retno Puji; Aprina, Aprina
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (164.429 KB) | DOI: 10.30604/jika.v7i1.920

Abstract

The direct causes of stunting under five are inadequate food consumption and infectious diseases. The two direct causal factors are closely related to the quality of parenting. Efforts to handle stunting toddlers must be carried out as early as possible, not only since the mother is pregnant but must be carried out since the mother is still a prospective bride. In this context, it is necessary to find a model for the development of training for prospective brides that is in accordance with the needs in preventing stunting under five and seeing its effectiveness. This study will use a combination of descriptive observational design and quasi-experimental design. The research population is prospective brides in Kemiling District, and the sample is determined by accident, namely prospective brides who have registered at KUA Kemiling District until July 2021. Data collection for the development of pre-wedding classes is carried out by means of FGD and interviews, while to assess the effect of class pre-marriage used a quasi-experimental design with pre and post-test approaches. The analysis was carried out descriptively (frequency distribution) to determine the pre-marital class and bivariate analysis (dependent and independent test) to determine the effect of pre-marital class on the knowledge of the prospective bride and groom in preventing stunting under five. The results showed that the standard competencies needed by prospective brides to prevent stunting under five were exclusive breastfeeding, complementary feeding, balanced nutrition, monitoring of toddler growth, infectious diseases in children, pregnancy, and reproductive health. In the case group that was given treatment in the form of leaflets and premarital classes, there was an increase in knowledge scores between 78.9% to 125.6%, while in the control group which was only given leaflets the increase in knowledge scores only rose by 25.9% to 91.6 %. The results of the dependent test showed that there was a significant difference in knowledge scores between before and after treatment. Meanwhile, the results of the independent test showed that there was a significant difference in knowledge scores on exclusive breastfeeding (p=0.000), complementary feeding (p=0.019), child growth monitoring (p=0.002), pregnancy (p=0.001), and reproductive health (p=0.001). = 0.020) between the two groups.
The Determinant Factors of Labor. Data Analysis of “Maternal Card Cohort” in Tawangharjo Community Health Center, Grobogan Purnami, Cahya Tri; Dharminto, Dharminto; Mawarni, Atik; Kurniawati, Yacinta Puji
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (682.886 KB) | DOI: 10.30604/jika.v7i1.822

Abstract

ANC data in the maternal card cohort register at the Puskesmas can be used to detect risk factors for pregnancy and labor that can prevent maternal death, but this data has never been analyzed. This study aims to analyze the determinants of labor in mothers who received ANC by a midwife according to the data in the maternal card cohort. This research is a descriptive-analytic study design using the observational method. Data sourced from the maternal card cohort register that meets the standards of accuracy and completeness of ANC results in records until labor in the 2019 time period. A total of 172 data were used as samples. Maternal characteristics, maternal mortality risk factors, levels of maternal risk factors based on the Poedji Rochjati score as independent variables, and the act of labor is the dependent variable. Univariate and bivariate analysis was carried out descriptively and analytically using the chi-square test. The majority of mothers aged 20-35 years (81.4%), had basic education (94.2%), normal nutritional status (84.9%), hadn’t anemia (80.2%), had normal blood pressure (70, 9%), hadANC visits 5-10 times (65.7%), categorized as low-risk pregnancy (86.6%), and almost all received normal labor in the previous (96.0%). Previous labor and maternal risk factors were associated with the last labor act received by the mother (p-value=0.040; p-value=0.043).Abstrak: Data pelayanan kehamilan (antenatal care) pada register kohort kartu ibu di Puskesmas dapat digunakan untuk mendeteksi faktor risiko kehamilan dan tindakan persalinan yang dapat mencegah kematian ibu, namun belum pernah dilakukan analisis pada data tersebut. Penelitian ini bertujuan menganalisis faktor-faktor penentu tindakan persalinan pada ibu yang mendapat ANC oleh bidan sesuai data pada kohort kartu ibu. Penelitian ini merupakan rancangan studi deskriptif analitik menggunakan metodeobservasional. Data yang digunakan bersumber pada register kohort kartu ibu yang memenuhi standar ketepatan dan kelengkapan catatan hasil ANC sampai persalinan dalam periode waktu 2019. Sebanyak 172 data memenuhi standar digunakan sebagai sampel. Variabel karakteristik ibu, faktor risiko kematian ibu, tingkatan faktor risiko ibu berdasar skor Poedji Rochjati sebagai variabel bebas, sedangkan variabel terikat adalah tindakan persalinan. Analisis data univariat dan bivariat dilakukan secara deskriptif dan analitik menggunakan uji chi square. Mayoritas ibu berumur 20-35 tahun (81,4%), berpendidikan dasar (94,2%), berstatus gizi normal (84,9%), tidak menderita anemia (80,2%), memiliki tekanan darah normal (70,9%), frekuensi kunjungan ANC antara 5-10 kali (65,7%), termasuk kategori kehamilan risiko rendah/KRR (86,6%), dan hampir seluruh ibu menerima tindakan persalinan normal pada persalinan sebelumnya (96,0%). Tindakan persalinan sebelumnya dan faktor risiko ibu berhubungan dengan tindakan persalinan terakhir yang diterima ibu (p-value=0,040; p-value=0,043).
Analysis of Inpatient Linen Management in Hospital Isolation Room in Indonesia: A Review Yulis Muktafi'ah; Antono Suryoputro; Septo Pawelas Arso
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 3: September 2021
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (609.829 KB) | DOI: 10.30604/jika.v6i3.1058

Abstract

Linen handling activities are a very important handling activity carried out in hospitals. The thing that can minimize the risk of distribution of linen is to carry out proper handling according to standards. If the handling is carried out properly, the risk of spreading microorganisms to activities, staff, and the environment can be carried out and minimized. The purpose of writing this article is to find out the analysis of inpatient linen management in isolation rooms in various hospitals in Indonesia. The method used in writing this article is a qualitative method with the strategy used is a literature study on the topic of analysis of linen management in hospital isolation rooms in Indonesia. The results of the literature from various sources found that hospitals in Indonesia had set standards for linen management to prevent transmission. However, linen management in various hospitals in Indonesia, in general, has not been able to run optimally and has not met the applicable standards. This can be seen from the various stages of handling linen that does not meet the standards starting from the stages of separation, reception, processing, washing, and storage.  Abstrak: Kegiatan penanganan linen merupakan sebuah kegiatan penanganan yang sangat penting dilakukan di rumah sakit. Hal yang dapat meminimalisir risiko penularan dari linen yaitu dengan melaksanakan penanganan yang tepat sesuai dengan standar. Jika kegiatan penanganan dilakukan dengan tepat, maka risiko penularan mikroorganisme pada pasien, petugas serta lingkungan dapat dicegah dan diminimalisir. Tujuan penulisan artikel ini yaitu untuk mengetahui analisis pengelolaan linen rawat inap ruang isolasi di berbagai rumah sakit di Indonesia. Metode yang digunakan dalam penulisan artikel ini yaitu metode kualitatif dengan strategi yang digunakan adalah studi literatur dengan topic analisis pengelolaan linen rawat inap ruang isolasi rumah sakit di Indonesia. Hasil tinjauan pustaka dari berbagai sumber yang ditemukan menyatakan bahwa rumah sakit di Indonesia sudah menetapkan standar pengelolaan linen untuk mencegah risiko penularan. Namun, pengelolaan linen di berbagai rumah sakit di Indonesia secara garis besar belum dapat berjalan dengan maksimal dan belum memenuhi standar ketentuan yang berlaku. Hal ini dapat dilihat dari berbagai tahap kegiatan penanganan linen yang belum memenuhi standar mulai dari tahap pemisahan, penerimaan, pengangkutan, pencucian dan penyimpanan.
Application of Ionic Liquids based Microwave-Assisted Extraction to Bioactive Compounds Comfrey (Symphytum officinale L.) Leaves Hasan, Nahrul; Mun'im, Abdul; Hayun, Hayun
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (816.251 KB) | DOI: 10.30604/jika.v7i1.764

Abstract

Extraction of bioactive compounds from comfrey leaves (Symphytum officinale L.) was carried out by comparing organic solvents and ionic liquids between conventional and microwave-assisted extraction (IL-MAE) methods. The comfrey leaf powder was extracted under various conditions. The types of organic solvents used are 65% ethanol and ionic liquids. The extraction methods used are reflux and microwave-assisted extraction. The ionic liquid was extracted by microwave-assisted extraction with the following conditions: ionic liquid concentration of 1 mol/L, the solid-liquid ratio of 1:20 (g/mL), extraction time of 10 minutes, and power of 30% (270 Watt). The total phenolic content of the extract was analyzed with a microplate reader. Allantoin and retrorsine N-oxide levels were analyzed by thin-layer chromatography – densitometry. MAE extraction in a solvent containing 65% ethanol resulted in the highest total phenolic content of 1.038±0.012. The highest levels of allantoin were also obtained from MAE extraction with 65% ethanol solvent at 2.922 ± 0.123. The highest levels of retrorsine N-oxide were obtained by extraction of MAE with (BMIM)Br with a concentration of 0.049 ± 0.007. Extraction of comfrey leaves using the MAE method of 65% ethanol produced the highest total phenolic and allantoin content compared to other methods. (BMIM) Br extraction with MAE can attract the highest retrorsine N-oxide in comfrey leaves.  Abstrak: Ekstraksi senyawa bioaktif daun komfrey (Symphytum officinale L.) dilakukan dengan membandingkan pelarut organik dan cairan ionik, antara metode konvensional dengan metode microwave assisted extraction. Serbuk daun komfrey diekstraksi dengan berbagai kondisi. Jenis pelarut organik yang digunakan yaitu etanol 65% dan cairan ionik. Metode ekstraksi konvensional yang dilakukan, yaitu refluks dan microwave-assisted extraction. Cairan ionik diekstraksi denganmicrowave-assistedextraction dengan kondisi: konsentrasi Cairan ionik 1 mol/L, Rasio padatcair 1:20 (g/mL), waktu ekstraksi 10 menit dan power 30% (270 Watt). Kadar fenol total dalam ekstrak dianalisis dengan microplate reader. Sedangkan kadar allantoin dan retrorsine N-oxide dianalis dengan kromatografi lapis tipis–densitometri. Ekstraksi MAE dengan pelarut etanol 65% menghasilkan kadar fenol total tertinggi, yaitu 1,038 ± 0,012. Kadar Allantoin tertinggi didapatkan juga dari ekstraksi MAE dengan pelarut etanol 65% sebanyak 2,922 ± 0,123. Kadar retrorsin N-oksida tertinggi didapatkan dengan ekstraksi MAE dengan (BMIM) Br dengan konsentrasi 0,049 ± 0,007. Ekstraksi daun komfrey dengan metode MAE etanol 65% menghasilkan kadar fenol total dan allantoin paling tinggi dibandingkan dengan metode lain. Ekstraksi (BMIM) Br dengan MAE dapat menarik kadar retrorsin N-oksida paling tinggi dalam daun komfrey.
Factors That Affect the Disaster Preparedness of Emergency Nurses in Public Health Center Suaida, Desi Holifatus; Handayani, Dian; Suryanto, Suryanto
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.53 KB) | DOI: 10.30604/jika.v7i1.905

Abstract

Disasters can result in damage to infrastructure, material losses, and even death. Nurses have an important role in disaster management, especially those who work in the emergency room. This study aims to determine the relationship between the length of work, education level, disaster training, response phase, self-efficacy, infrastructure, and family support with disaster preparedness. This study used a cross-sectional design. The sample is 96 nurses, the sampling technique uses Total Sampling and the analysis uses the Spearman Rank test. The results of this study indicate that there is no relationship between length of service (p-Value = .148, r = .149), level of education (p-Value = .460, r = .076), response phase (p-Value = .410, r = - .085), whereas disaster training (p-Value = .009, r = .265), self efficacy (p-Value = .000, r = .702), infrastructure (p-Value = .000, r = .603), support families (p-Value = .003, r = .298) with disaster preparedness. There is no relationship between the length of work, level of education, and response phase with disaster preparedness. while disaster training, self-efficacy, infrastructure, and family support have a relationship with disaster preparedness. Health centres need to prepare infrastructure because they can be a supporting factor in increasing the readiness of nurses in disaster management.Abstrak: Bencana dapat mengakibatkan kerusakan infrastruktur, kerugian material bahkan menyebabkan kematian. Perawat memiliki peran penting dalam manajemen bencana terutama yang bekerja di IGD. Penelitian ini bertujuan untuk mengetahui hubungan lama kerja, tingkat pendidikan, pelatihan bencana, fase respon, self efficacy, sarana prasarana dan dukungan keluarga dengan kesiapsiagaan bencana. Penelitian ini menggunakan desain cross sectional. Sampel sebanyak 96 Perawat, teknik sampling menggunakan Total Sampling dan analisis menggunakan uji Spearman Rank. Hasil penelitian ini menunjukkan tidak ada hubungan antara lama kerja (p Value = .148,  r = .149), tingkat pendidikan (p Value = .460,  r = .076), fase respon (p Value = .410,  r = - .085), sedangkan pelatihan bencana (p Value = .009,  r = .265), self efficacy (p Value = .000,  r = .702), sarana prasarana (p Value = .000,  r = .603), dukungan keluarga (p Value = .003,  r = .298) ada hubungan dengan kesiapsiagaan bencana. Tidak terdapat hubungan lama kerja, tingkat pendidikan dan fase respon dengan kesiapsiagaan bencana sedangkan pelatihan bencana, self efficacy, sarana prasarana dan dukungan keluarga terdapat hubungan dengan kesiapsiagaan bencana. Puskesmas perlu mempersiapkan sarana  prasarana karena dapat menjadi faktor pendukung dalam meningkatkan kesiapan perawat dalam manajemen bencana.
Clinical Manifestations and Behavior Changes in Rats Treated with Jamaican Cherries Extract (Muntingia calabura) Afdhaliya, Noor Khalwati; Indarto, Dono; Wasita, Brian
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (680.65 KB) | DOI: 10.30604/jika.v7i1.878

Abstract

Iron deficiency anemia (IDA) in female adolescents is one of the health problems, which occupied 8th position as a cause of global disability and is the main cause of anemia in reproductive women. Iron tablet supplementation is the government program to reduce IDA prevalence in Indonesia but often results in gastrointestinal side effects. Jamaican cherries fruits contain vitamin C, iron and flavonoids, which play essential roles in iron metabolism. This study aimed to investigate the effects of Jamaican cherries fruits ethanol extract on clinical manifestations and behavior changes in female Wistar rats. This randomized controlled trial with pre-posttest control group design used 24 female Wistar rats, aged 10 -12 weeks and were randomly divided into 6 groups: N, positive control (PC: AIN-93M low iron food + elemental iron) and treatments (T1-4: AIN-93M low iron food + 0.26, 0.35, 0,5 or 0.75g/ 100g Body Weight (BW) Jamaican cherries fruits extract respectively for 28 days). Clinical manifestations, reflexes and behavior changes were observed at day 0, 14 and 28 interventions. BW data were analyzed using one way ANOVA and repeated measures ANOVA tests. All rats had normal reflexes and did not show clinical manifestations and behavior changes. The average of rat BW in T1-4 groups did not significantly differ before (p=0.896), during (p=0.884) and after treatment (p=0.775) but the average of rat BW in the T1 group increased significantly (p=0.012). In conclusion, administering Jamaican cherries fruits ethanol extracts up to 0.75g/100g BW has no toxic effects in female Wistar rats.  Abstrak: Anemia defisiensi besi (ADB) pada remaja putri merupakan salah satu masalah kesehatan yang menempati posisi ke-8 sebagai penyebab disabilitas tingkat global dan penyebab utama anemia pada ibu hamil. Suplementasi tablet besi merupakan program pemerintah untuk mengurangi prevalensi ADB di Indonesia tetapi sering menimbulkan efek samping di saluran percernaan. Buah kersen mengandung vitamin C, zat besi dan flavonoids yang berperan penting dalam metabolisme besi. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak buah kersen terhadap manifestasi klinis dan perubahan perilaku tikus Wistar betina. Penelitian randomized controlled trial ini dengan pre-posttest control group design dengan menggunakan 24 ekor tikus Wistar betina umur 10 -12 minggu dan dibagi secara acak menjadi 6 kelompok: normal, kontrol posistif (KP) dan perlakuan (P1-4). Tikus di KP diberi pakan AIN-93M dengan besi rendah + besi elemental sedangkan P1-4 diberi pakan yang sama ditambah 0.26, 0.35g, 0,5g atau 0.75g/100g berat badan (BB) secara berturut-turut ekstrak buah kersen selama 28 hari. Manifestasi klinis, reflek dan perubahan perilaku tikus diamati pada hari ke-0, 14 dan 28. Data BB dianalisis menggunakan uji one way ANOVA dan uji repeated measures ANOVA. Semua tikus memiliki reflek yang normal dan tidak menunjukkan manifestasi klinis dan perubahan perilaku. Rerata BB tikus pada P1-4 tidak berbeda signifikan sebelum (p=0,896), selama (p=0,884), maupun setelah perlakuan (p=0,775) tetapi rerata BB tikus P1 meningkat secara signifikan (p=0,012). Kesimpulan, pemberian ekstrak buah kersen hingga 0,75g/100g BB tidak menyebabkan toksisistas tikus Wistar betina.
Pengaruh Susu Kuda Liar Sumbawa Terhadap Kadar TNF-a pada Tikus Gastritis yang Diinduksi Indometasin Musyarrafah, Musyarrafah; Wanadiatri, Halia; Merta, Putu Demas Ardina; Adnyana, I Gede Angga; Rozikin, Rozikin; Luktiana, Metha
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 4: December 2021
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (677.007 KB) | DOI: 10.30604/jika.v6i4.1031

Abstract

Gastritis is an inflammatory, irritating, or erosive condition that affects the mucosa submucosa of the stomach. Uncontrolled use of NSAIDs for a long time can cause excess stomach acid that will lead injury to the gastric lumen which results in the immune system release of pro-inflammatory factors, one of which is TNF-a. This study aims to determine the effect of Sumbawa’s mare milk (SMM) on TNF-a Levels in Wistar Rats with Indomethacin-induced gastritis. This study used 24 male Wistar rats which were divided into 4 treatment groups, namely negative control group (group 1), positive control group (group 2), SMM treatment group + Indomethacin (group 3), and SMM treatment group (group  4). Treatment was given for 14 days analyzed using an ELISA reader. Group 3 showed the highest levels of TNF-a (median=52.36). While group 4 got the lowest TNF-a level (median=24.49). In the control group, TNF-a levels were higher in group 1(median=35.14) than in group 2 (median=30.14). Results showed that SMM had a significant effect on TNF-a levels (p less than 0.05). Effects that can be given vary, either decreasing or increasing TNF-a depending on the conditions in the tissue. SMM has the potential not only as a preventive treatment but also as a curative treatment.Abstrak: Gastritis adalah kondisi inflamasi, iritasi, maupun erosif yang mengenai daerah mukosa dan submukosa lambung. Pemakaian NSAID yang tidak terkontrol dalam waktu lama dapat mengakibatkan asam lambung berlebih sehingga mukosa lambung terkikis. Perlukaan pada lumen lambung akan membuat sistem imun mengeluarkan faktor proinflamasi, salah satunya adalah TNF-a, sehingga terjadi gastritis. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian susu kuda liar Sumbawa terhadap kadar TNF-a pada Tikus Gastritis yang diinduksi Indometasin. Penelitian ini menggunakan 24 ekor tikus jantan galur Wistar yang dibagi menjadi 4 kelompok perlakuan yaitu kelompok kontrol negatif (kelompok 1), kelompok kontrol positif (kelompok 2), kelompok perlakuan SKL (Susu Kuda Liar) Sumbawa + Indometasin (kelompok 3), dan kelompok perlakuan SKL (kelompok 4). Perlakuan diberikan selama 14 hari dan dilakukan analisis menggunakan ELISA-reader. Kelompok 3 menunjukkan kadar TNF-a tertinggi (median=52,36). Sedangkan kelompok 4 mendapatkan kadar TNF-a terendah (median=24,49). Pada kelompok kontrol, kadar TNF-a lebih tinggi pada kelompok 1 (median=35,14) dibandingkan dengan kelompok 2 (median=39,74). Hasil penelitian menunjukkan bahwa susu kuda liar Sumbawa berpengaruh terhadap kadar TNF-a secara signifikan (p kurang dari 0,05). Pengaruh yang dapat diberikan beragam, baik menurunkan maupun meningkatkan kadar TNF-a tergantung dengan kondisi di jaringan tersebut. SKL Sumbawa tidak hanya berpotensi sebagai pengobatan preventif namun juga sebagai pengobatan kuratif.
Designing Integrated Patient Safety Incident Reporting with Hospital Information System Sutejo Sutejo; Agung Budi Prasetijo; Farid Agushybana
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 3: September 2021
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1028.856 KB) | DOI: 10.30604/jika.v6i3.968

Abstract

Incident reporting systems are designed to obtain patient safety information that is used for organizational and individual learning. Currently, the recording of patient safety incident reports has been facilitated by the ministry of health through the implementation of the quality of health facilities, especially for incidents with unexpected events (KTD) or sentinels. Incident recording in hospitals is still very weak, so incident data cannot be analyzed properly and correctly to improve the quality of hospital services. This study aims to design an Integrated Patient Safety Incident Reporting Information System (SIPIKAT). The design of SIPIKAT uses the Systems Development Life Cycle (SDLC) method with the Framework for the Application of System Techniques (FAST). In-depth interviews and Focus Group Discussions (FGD) were conducted to obtain the necessary data. This web-based SIPIKAT is designed using PHP 5.6 and Javas-script, MySQL database, and Apache webserver. SIPIKAT integration with Hospital Information System (SIMRS) via web service to retrieve patient identity data including name; date of birth and medical record number. The output is in the form of incident report information and risk grading to be followed up. Conclusion SIPIKAT Research is easy to use and generates information on risk aggregation required for follow-up.  Abstrak: Sistem Pelaporan Insiden Keselamatan Pasien dirancang untuk memperoleh informasi tentang keselamatan pasien yang digunakan untuk pembelajaran organisasi dan individu. Saat ini, pencatatan laporan insiden keselamatan pasien telah difasilitasi oleh kementerian kesehatan melalui penerapan mutu fasilitas kesehatan, terutama untuk insiden dengan kejadian tak terduga (KTD) atau sentinel. Pencatatan insiden di rumah sakit masih sangat lemah, sehingga data insiden tidak dapat dianalisis dengan baik dan benar untuk meningkatkan kualitas pelayanan rumah sakit. Penelitian ini bertujuan untuk merancang Sistem Informasi Pelaporan Insiden Keselamatan Pasien Terpadu (SIPIKAT). Perancangan SIPIKAT menggunakan metode Systems Development Life Cycle (SDLC) dengan Framework for the Application of System Techniques (FAST). Wawancara mendalam dan Focus Group Discussion (FGD) dilakukan untuk mendapatkan data yang diperlukan. SIPIKAT berbasis web ini dirancang dengan menggunakan PHP 5.6 dan Javas-cript, database MySQL, dan web server Apache. Integrasi SIPIKAT dengan Sistem Informasi Rumah Sakit (SIMRS) melalui web service untuk mengambil data identitas pasien termasuk nama; tanggal lahir dan nomor rekam medis. Outputnya berupa informasi laporan insiden dan risk grading untuk ditindaklanjuti. Kesimpulan Penelitian SIPIKAT mudah digunakan dan menghasilkan informasi tentang agregasi risiko yang diperlukan untuk tindak lanjut.

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