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All Journal Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Farmasi Klinik Indonesia JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Pendidikan dan Konseling Jurnal Penelitian Farmasi dan Herbal Pharmaceutical Sciences and Research (PSR) Jurnal Pengabdian Nasional (JPN) Indonesia kawanad Jurnal Sains dan Kesehatan
Numlil Khaira Rusdi, Numlil Khaira
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Education Electrical & Electronics Engineering Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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ANALISIS PERBEDAAN PENGOBATAN DIABETES MELITUS TIPE II PADA PASIEN BPJS DAN PASIEN UMUM Islam, Zainul; Rusdi, Numlil Khaira; Nurhasnah, Nurhasnah
Media Farmasi: Jurnal Ilmu Farmasi Vol 14, No 2 : September 2017
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.819 KB) | DOI: 10.12928/mf.v14i2.11240

Abstract

Peningkatan prevalensi diabetes akan meningkatkan biaya pengobatan. BPJS diberlakukan di Indonesia sejak tahun 2014 dan sistem klaimnya menggunakan tarif INA CBGs. Rumah sakit harus dapat melakukan penghematan sehingga tarif INA CBGs menutupi seluruh biaya pasien. Salah satu penghematan adalah dengan menggunakan obat yang ada dalam formularium nasional atau obat generik terpilih. Tapi masih banyak masyarakat yang menganggap obat generik adalah obat murah dan tidak berkualitas. Penelitian ini bertujuan untuk menganalisis perbedaan pengobatan Diabetes Melitus pada pasien BPJS dan pasien umum dilihat dari lama rawat, penurunan kadar gula darah dan biaya terapi. Pengambilan data dilakukan secara retrospektif di tiga rumah sakit. Data dianalisa terhadap 50 pasien umum dan 129 pasien BPJS dengan SPSS-22 menggunakan uji T dan Mann-Whitney. Hasil penelitian menunjukkan  tidak ada perbedaan antara pasien BPJS dan pasien umum dalam hal lama pasien dirawat (p=0,219), penurunan kadar gula darah sewaktu (p=0,509) dan ada perbedaan yang signifikan dari biaya rata-rata terapi obat pada pasien BPJS  dan pasien umum (p=0,030). Hasil penelitian tidak ada perbedaan penurunan kadar gula darah dan lama pasien di rawat di rumah sakit pada pasien BPJS dan pasien umum, sehingga dapat disimpulkan kualitas pelayanan pasien BPJS dan pasien umum adalah sama. Perbedaan terdapat pada biaya pengobatan, dimana biaya pengobatan pasien BPJS lebih murah dibandingkan dengan pasien umum sehingga pasien BPJS lebih diuntungkan dari pasien umum.
Evaluation of sperm quality in male rats treated with Sauropus androgynus (L.) merr. leaf fractions Ni Putu Ermi Hikmawanti; Numlil Khaira Rusdi; Silvy Yulida
Pharmaciana Vol 10, No 2 (2020): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.35 KB) | DOI: 10.12928/pharmaciana.v10i2.13514

Abstract

Sauropus androgynus (L.) Merr. or katuk is one of the medicinal plants broadly used in Indonesia as it has active compounds that can, among others, stimulate reproductive hormones. This study was aimed to determine which active fraction of S. androgynus leaves that have the potential to improve the sperm quality of male rats based on three parameters, namely sperm count, viability, and motility. It employed fractionation using the liquid-liquid technique with n-hexane, ethyl acetate, and water solvents to obtain the fractions. Twenty-four mature Sprague-Dawley male rats were divided into four equal groups: the normal group (untreated group) received 0.5% Na-CMC suspense, and the three fraction groups were given the n-hexane, ethyl acetate, and water fraction p.o., respectively, at the dose of 11.85 mg.Kg-1 BW daily for seven days. Sperm count, viability, and motility were measured on Day 8 (after treatment) from the sperm samples collected at the cauda epididymis of the sacrificed test rats. The results showed that compared with the normal group, the n-hexane and ethyl acetate fractions significantly increased the three parameters (p<0.05). Therefore, the S. androgynus leaf fractions have the potential as a natural material that can increase the fertility of male rats. 
Pola Pengobatan Fluor Albus Di Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo Serta Faktor-Faktor Yang Mempengaruhinya (Analisis Data Rekam Medik Tahun 2006-2007) Rusdi, Numlil Khaira; Trisna, Yulia; Soemiati, Atiek
Majalah Ilmu Kefarmasian Vol. 5, No. 2
Publisher : UI Scholars Hub

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Abstract

The objectives of this study were to know (1) Patients’ characteristics (2) The most etiology of leucorrhoea (3) Association between clinical manifestations or genital symp-toms with etiology of leucorrhoea (4) Therapy management of leucorrhoea by obstet-ric-gynecologist and venereologist (5) Factors influenced the treatment of leucorrhoea (6) Compliance with hospital therapeutic guidelines. The study was cross sectional and retrospective. A total of 437 patients hospitalized from January 2006-December 2007 were included. The results showed that leucorrhoea was found in 17,6% of patients at sexually transmitted disease clinic and 82,4% of patients at obstetric-gynecology clinic. The majority of patients were in productive age, married, and housewife, with most of genital symptoms were pruritus and curd-like vaginal dis-charge. The most of etiology leucorrhoea in this study was candidiasis. Statistically, there were association between genital symptoms with candidiasis and bacterial vaginosis (p<0,05). The specific genital symptoms of candidiasis were pruritus and curd-like vaginal discharge, whereas for bacterial vaginosis were homogeneous and increased vaginal discharge. There were different treatments of vaginal discharge be-tween obstetric-gynecologist and venereologist. For candidiasis, the obstetric-gyne-cologist preferred to use fluconazole, and metronidazole+nystatin (Flagistatin®); whereas the venereologist used clotrimazole and itraconazole. For bacterial vaginosis, obstet-ric-gynecologist used clindamycin and metronidazole+nystatin (Flagistatin®), while venereologist preferred to use metronidazole. For trichomoniasis there was no different treatment between obstetric-gynecologist and venereologist. In pregnancy, antibiot-ics used to treat leucorrhoea were clindamycin, fluconazole, metronidazole+nystatin (Flagistatin®), metronidazole, and nystatin. Prescribing compliance with the hospi-tal therapeutics guidelines were 37,8%. The type of antibiotics used were azitromycin, clindamycin, clotrimazole, doxycycline, fluconazole, itraconazole, ketoconazole, and metronidazole. Statistics analysis by Logistic regression (Cl 95%) showed that factors influenced the treatment of leucorrhoea included genital symptoms (OR = 0,975), risk factors (OR = 0,917), etiology (OR = 1,103), and comorbid diseases (OR = 1,387).
Aktivitas Afrodisiaka Fraksi dari Ekstrak Etanol 70% Daun Katuk (Sauropus androgynus (L). Merr) Pada Tikus Putih Jantan Rusdi, Numlil Khaira; Hikmawanti, Ni Putu Ermi; Maifitrianti, Maifitrianti; Ulfah, Yuanita Sofiana; Annisa, Ayyoehan Tiara
Pharmaceutical Sciences and Research Vol. 5, No. 3
Publisher : UI Scholars Hub

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Abstract

Decreased of libido is illustrated with disinterest in sexual activity caused by erectile dysfunction, impotence, and infertility. It can be treated by aphrodisiac agents. Katuk or Sauropus androgynus (L). Merr has long been used as a medicinal plant. The aim of this research was to evaluate which fraction of katuk leaf ethanol extract that had the aphrodisiac activity with parameters of climbing, introduction and the weight of testicular and seminal vesicle of male rat. Sprague-Dawley male rats as animals model divided into five groups: the normal control group, the positive control group (X-gra®), the n-hexane, ethyl acetate and water fraction groups in which each fraction group given a dose of 11.85 mg/kg body weight. The number of climbing and introductions were calculated on 0, 1st, 3th, and 5th day. The data were tested statistically with one-way ANOVA test followed by Tukey test. The weight of testicular and seminal vesicle of male rat were observed on the 15th day. Previously, rats were anesthetized using ketamine and then performed surgery. The results showed that the n-hexane fraction (11.85 mg/kg body weight) increased libido with the average number of climbing was 16.5 times and the average number of introductions was 27.75 times. It was also able to increase the weight of testicular and seminal vesicle of male rat compare to positive control (X-gra® 51.37 mg/kg body weight). The compounds contained in n-hexane fraction are terpenoids and steroids.
Pengaruh Fasilitas dan Pelayanan Petugas Instalasi Farmasi terhadap Kepuasan Pelanggan dan Dampaknya Terhadap Loyalitas Pelanggan Endang Sulistyaningsih; Numlil Khaira Rusdi
Jurnal Pendidikan dan Konseling (JPDK) Vol. 4 No. 6 (2022): Jurnal Pendidikan dan Konseling
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jpdk.v4i6.8411

Abstract

Instalasi Farmasi Rumah Sakit (IFRS) sebagai unit Revenue Center, berperan meningkatkan pendapatan RS dituntut mampu memberikan pelayanan untuk kepuasan pelanggan yang berdampak pada loyalitas pelanggan. Penelitian ini bertujuan mengetahui pengaruh fasilitas (X1) dan pelayanan petugas (X2) terhadap loyalitas pelanggan (Z) melalui kepuasan pelanggan (Y) sebagai variabel intervening. Populasi penelitian ini adalah pelanggan rawat jalan yang pernah berobat paling sedikit tiga kali di RS X Jakarta Utara yang sedang menunggu pelayanan resep di IFRS. Jumlah sampel 100 diperoleh menggunakan rumus Slovin dengan teknik simple random sampling dan analisis data menggunakan analisis jalur (Path Analysis). Hasil penelitian menunjukkan terdapat hubungan bermakna antara X1, X2 dan Y terhadap Z (p = 0,044, 0,006 dan 0,000) sedangkan nilai koefisien determinasi X1 terhadap Y sebesar 80,6%; dan Y terhadap Z sebesar 4,3%. Pengaruh X1 secara langsung terhadap Z adalah 7,4% dan terhadap Y = 18,7%. Pengaruh total X1 terhadap Z gabungan pengaruh langsung dan tidak langsung sebesar 26,1% dan pengaruh X2 terhadap Y sebesar 24,1%. X1, X2, dan Y berpengaruh terhadap Z sebesar 90,1%. X2 tidak berpengaruh secara signifikan terhadap Y (p= 0,120). Penelitian ini menyimpulkan bahwa fasilitas, pelayanan petugas, dan kepuasan pelanggan berpengaruh positif dan signifikan terhadap loyalitas pelanggan.
Optimalisasi Penggunaan Antibiotik: Program Edukasi dan Pemahaman Risiko Resistensi Antibiotik di SMK Swadaya Global Jakarta Numlil Khaira Rusdi; Maifitrianti; Nurhasnah
Kawanad : Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 1 (2024): March
Publisher : Yayasan Kawanad

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56347/kjpkm.v3i1.190

Abstract

Antibiotic resistence is a serious global problem that can increase morbidity, mortality and medical costs. Vocational school students can act as agents of change to prevent antibiotic misuse in society. This service activity was carried out at SMK Swadaya Global School, Buaran, East Jakarta with a total of 30 participants. Education was carried out with lectures and followed by a Forum Group Discussion (FGD). Students were divided into 3 groups and each group was accompanied by a facilitator. Each group was given a case about the use of antibiotics in the community. The service activities were carried out well and students participated in the activities enthusiastically during the activities. The results of the Wilcoxon analysis showed that there was an increase in students' knowledge and attitudes towards antibiotic use after the activity (p value< 0.001).
HUBUNGAN PENGETAHUAN DAN SIKAP MASYARAKAT KECAMATAN CAKUNG JAKARTA TIMUR TERHADAP PENGGUNAAN DAN RESISTENSI ANTIBIOTIK Rusdi, Numlil Khaira; Hastuti, Septianita Hastuti; Maifitrianti, Maifitrianti; Nurhasnah, Nurhasnah; Azizah, Rahma Nur
Jurnal Penelitian Farmasi Dan Herbal Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i2.1748

Abstract

Antibiotic resistance is one of the serious problems that are being faced today. Low levels of knowledge and poor public attitudes about antibiotic use can trigger resistance. This study aims to determine the level of knowledge, attitudes, and relationships between the level of knowledge and attitudes of the community about antibiotic use and resistance in Cakung District, East Jakarta for the July-August 2023 period. The design of this study was descriptive with cross sectional method. The sampling technique uses purposive sampling. The source of data in this study is primary data in the form of knowledge questionnaires and attitudes about antibiotics. Knowledge is categorized with high and low, while attitude is categorized with positive and negative. The results showed that as many as 400 respondents met the inclusion and exclusion criteria. The characteristics of public knowledge about antibiotics showed that 65.3% of respondents had high knowledge and 34.7% had low knowledge. As many as 61.0% of respondents had a positive attitude and 39% had a negative attitude towards the use of antibiotics and resistance. The results of the bivariate analysis showed that there was a significant relationship between the level of knowledge and people's attitudes towards antibiotic use and resistance (P<0.000). The higher the level of knowledge of the community, the more positive the attitude of the community towards the wise use of antibiotics.
Ketepatan Obat, Dosis, dan Potensi Interaksi Obat pada Pasien Kanker Paru di Rumah Sakit X Jawa Barat Periode 2019-2021: Appropriate Use of Medicines, Doses, and Potential Drug Interactions in Lung Cancer Patients at X Hospital West Java for the 2019-2021 Period Numlil Khaira Rusdi; Evi Novita Sari; Nora Wulandari
Jurnal Sains dan Kesehatan Vol. 5 No. 3 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i3.1754

Abstract

Lung cancer is the most common disease found in the world and is one of the biggest causes of mortality in cancer. Lung cancer is the main cause of death from cancer in the male population and also has a fairly high percentage of new cases in the female population. This study aims to analyze the accuracy of chemotherapy regimens and the potential for drug interactions in lung cancer patients at X Hospital West Java for the 2019-2021 period. This study used a descriptive method with a retrospective data collection technique from medical records of lung cancer patients at Hospital X West Java for the 2019-2021 period. The toolkit were NCCN (National Comprehensive Cancer Network) 2021, National Formulary 2019, and Drugs Interaction Checker (www.drugs.com). Based on the drug regimen used, 94 patients (89.52%) got the right medication, and 71 patients (67.62%) got the right dose. The regimen was inappropriate, namely carboplatin-etoposide in 6 patients (54.50%), cisplatin-doxorubicin in 1 patient (9.10%), carboplatin-vinorelbine in 1 patient (9.10%). There were 482 cases of potential drug interactions. Drug interactions occurred at a major significance level was 34 cases (7.05%), a moderate significance level was 425 cases (88.17%) and a minor significance level was 23 cases (4.78%). Keywords: Lung Cancer, medicine, dose, Drug interactions Abstrak Kanker paru merupakan salah satu penyebab kematian terbesar di dunia. Di Indonesia, Kanker paru merupakan jenis kanker dengan kasus baru tertinggi dan penyebab utama kematian pada penduduk laki-laki dan perempuan. Penelitian ini bertujuan untuk menganalisis ketepatan regimen kemoterapi serta potensi interaksi obat pada pasien kanker paru di Rumah Sakit X Jawa Barat periode 2019-2021. Penelitian ini menggunakan metode deskriptif. Pengumpulan data dilakukan secara retrospektif dari data rekam medik pasien kanker paru di Rumah Sakit X Jawa Barat periode 2019-2021. Toolkit yang digunakan NCCN (National Comprehensive Cancer Network) 2021, Formularium Nasional (Fornas) 2019, dan Drugs Interaction Checker yaitu www.drugs.com. Berdasarkan regimen obat yang digunakan terdapat 94 pasien (89,52%) tepat obat, dan 71 pasien (67,62%) tepat dosis. Hasil penelitian menunjukan regimen yang tidak tepat yaitu carboplatin-etoposid 6 pasien (54,50%), cisplatin-doxorubicin 1 pasien (9,10%), carboplatin-vinorelbin 1 pasien (9,10%). Dari total keseluruhan pasien terdapat potensi interaksi obat sebanyak 482 kasus. Interaksi obat yang terjadi pada tingkat signifikansi mayor sebanyak 34 kasus (7,05%), tingkat signifikansi moderat sebanyak 425 kasus (88,17%) dan tingkat signifikansi minor 23 kasus (4,78%). Kata Kunci: Kanker Paru, Obat, dosis, Interaksi obat
Sosialisasi Cara Pembuangan Obat Rusak, Tidak Terpakai, dan Kedaluwarsa pada Masyarakat Maifitrianti; Rusdi, Numlil Khaira; Nurhasnah
Jurnal Pengabdian Nasional (JPN) Indonesia Vol. 6 No. 1 (2025): Januari
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LPPM) STMIK Indonesia Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35870/jpni.v6i1.1199

Abstract

The community's habit of storing unnecessary, expired, and damaged medicines as well as the lack of knowledge about the correct way to dispose of medicines are problems that need to be followed up. One of the efforts to increase community knowledge is through education on how to properly dispose of medicines. Education through this service activity was carried out in the community in RT 004, RW 013 Pasir Angin Village, Cileungsi, West Java. Education was provided using the lecture method and leaflet media. The level of knowledge was assessed using a questionnaire before and after education. The service activities have been carried out well and the participants were enthusiastic during the activities. The results of the knowledge score analysis showed that there was a significant increase in knowledge before and after the activity (p<0.05).
Kualitas Hidup Pasien Kanker Payudara Menggunakan Kuesioner QLQ BR-23 di Rumah Sakit Kanker Dharmais Jakarta Barat Numlil Khaira Rusdi; Iskandar Iskandar; Maifitrianti Maifitrianti; Nurhasnah Nurhasnah; Endang Sulistyaningsih; Lia Desviana Safitri
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 9, No 2 (2024)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v9i2.84445

Abstract

Masalah utama pasien kanker payudara dalam jangka panjang berkaitan dengan masalah psikososial dan gejala fisik khususnya efek samping dari terapi adjuvant sistemik/ kemoterapi pada kualitas hidup. Penelitian ini bertujuan untuk menilai kualitas hidup pasien kanker payudara di instalasi rawat jalan Rumah Sakit Kanker Dharmais Jakarta Barat dan mengevaluasi faktor-faktor yang mempengaruhi kualitas hidup pasien. Desain penelitian menggunakan studi kohort. Kualitas hidup pasien kanker payudara dinilai menggunakan kuesioner EORTC QLQ-BR23 dengan kategori baik, sedang, dan buruk. Faktor-faktor yang mempengaruhi kualitas hidup dianalisis menggunakan regresi linear. Hasil penelitian menunjukkan, kualitas hidup berdasarkan skala fungsional; untuk domain citra tubuh terkategori baik, fungsi seksual terkategori buruk, kenikmatan seksual dan pandangan masa depan terkategori sedang. Kualitas hidup berdasarkan skala gejala; pada domain efek terapi, gejala pada payudara, gejala pada lengan, dan gejala pada rambut termasuk kategori baik. Faktor-faktor yang mempengaruhi kualitas hidup adalah usia 50 tahun keatas, postmenopause, mastektomi, dan stadium lanjut (p
Co-Authors Annisa, Ayyoehan Tiara Atiek Soemiati Atiek Soemiati Ayyoehan Tiara Annisa Bariroh, Tahyatul Endang Sulistyaningsih Endang Sulistyaningsih Evi Novita Sari Fujianti, Fujianti Hadi Sunaryo Hariyanti Hariyanti Hastuti, Septianita Hastuti Imani, Ilfasa Ashala Noer Iskandar Iskandar Islam, Zainul Islam, Zainul Isra, Rafiq Al Kasianto Lestiani, Lestiani Lia Desviana Safitri Listiyanti, Melly Maifitrianti Maifitrianti Maifitrianti Maifitrianti Maifitrianti Maifitrianti Maifitrianti Maifitrianti, Maifitrianti Negara, Tigo Ramansyah Prawira Ni Putu Ermi Hikmawanti Nora Wulandari Nurhasnah Nurhasnah Nurhasnah Nurhasnah Nurhasnah Nurhasnah Nurhasnah Rahma Nur Azizah Rahmat, Amalia Rini Prastiwi Silvy Yulida Ulfah, Yuanita Sofiana Yuanita Sofiana Ulfah Yulia Trisna Yulia Trisna, Yulia Zahra, Mutia