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INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 336 Documents
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Formulasi masker gel peel-off “ELCI” (Eleutherine palmifolia dan Citrus reticulata) sebagai antioksidan Kumalasari, Eka; Prihandiwati, Erna; Nafisa Berliana, Siti; Marta Fransiska, Revita
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/x8hk1p37

Abstract

UV radiation can cause skin damage, including premature aging. Preventing premature aging can be accomplished by the use of cosmetic goods, such as a peel-off gel mask. ELCI is a unique peel-off gel mask with Dayak leek extract (Eleutherine palmifolia) and orange peel extract (Citrus reticulata). These two active compounds have extremely high antioxidant activity. Antioxidants can help prevent aging by reducing ROS generation. The goal of the study is to find the best ELCI peel-off gel mask recipe thatmeets the standards and provides the most synergistic advantages achievable. ELCI is derived from oven-dried plants and extracted utilizing a maceration procedure with 70% ethanol as the solvent. ELCI was divided into three formulae with varying extract compositions for laboratory testing of the preparation's physical qualities. The study found that all ELCI peel-off gel mask compositions passed the physical characteristics test, which included organoleptic, homogeneity, adhesive power, spreadability, pH, dry time, and viscosity. All formulations remained stable during storage after undergoing a 6-cycle cycling test was not significantly different (p>0,05).
FORMULASI DAN EVALUASI FISIK SEDIAAN TABLET NANOPARTIKEL EKSTRAK DAUN DADANGKAK (Hydrolea spinosa L.) Niah, Rakhmadhan; Wahyuono, Subagus; Prihandiwati, Erna
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jdkpqw89

Abstract

The utilization of traditional medicines offers a safer alternative for treatment, particularly regarding side effects and toxicity. One herbal plant known for its antioxidant activity is dadangkak leaves (Hydrolea spinosa L.), containing flavonoids, polyphenols, and tannins. Ethanolic extracts of dadangkak leaves with antioxidant potential need development into tablet dosage forms. This study aims to determine the optimal formula for nanoparticle tablets containing dadangkak leaf extract. The extract was obtained via maceration using 96% technical ethanol, followed by evaporation to produce a thick extract. Nanoparticles were prepared by mixing the extract with 96% technical ethanol, distilled water, a chitosan solution in acetic acid, and a NaTTP solution. Particle size was analyzed using a Particle Size Analyzer (PSA). Tablet formulations involved varying concentrations of Na alginate and Avicel PH 102, using direct compression. Results showed that Na alginate and Avicel PH 102 concentrations affected tablet physical properties. Avicel PH 102 increased hardness and disintegration time, while Na alginate increased friability. Based on evaluations, formula 2 was determined to be the best.
AKTIVITAS ANTIOKSIDAN DAN SITOTOKSIK EKSTRAK ETANOL DAUN KARAS TULANG (Chloranthus erectus) TERHADAP SEL HELA Prastanti, Rovina Friska; Haryoto
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/w23sjv62

Abstract

Karas tulang (Chloranthus erectus) is a type of herbal plant commonly  found in tropical climates, including Indonesia. Previous research has shown that plants from the Chloranthus genus contain chemical compounds such as flavonoids, which have potential as antioxidants and anticancer agents. This research aims to determine the compound content, test the radical inhibitory activity, and evaluate the cytotoxic activity of karas tulang (Chloranthus erectus) leaves. Antioxidant activity was tested using the DPPH method, with vitamin C as a comparison, while cytotoxicity testing was conducted using the MTT method, with doxorubicin as a positive control. Additionally, a phytochemical screening test was permormed to identify the groups of chemical compounds present in the ethanol extract of karas tulang leaves. The results of the research show that the ethanol extract of karas tulang leaves has very strong antioxidant activity, indicated by an IC50 value of 36.74 μg/mL. Meanwhile, the IC50 value for the cytotoxic test is 163 μg/mL, which falls within the moderate activity category. Based on these test results, it can be concluded that the ethanol extract of karas tulang leaves has the potential to be developed as a safe chemopreventive agent
FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER CLAY KOMBINASI EKTRAK ETANOL DAUN BAWANG DAYAK DAN KULIT JERUK SIAM Musiam, Siska; Ma'ruf, Muhammad; Kumalasari, Eka
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i3.2298

Abstract

Clay masks are a popular cosmetic due to their ability to rejuvenate the skin and detoxify the face. Clay masks can be made by adding dayak onion leaves and Siamese banjar orange peel, known to be rich in natural antioxidants containing various complex secondary metabolites. The aim of this research is to formulate and evaluate a clay mask preparation made from a combination of ethanol extracts of dayak onion leaves and Siamese banjar orange peel. The samples were extracted using the maceration method with 70% ethanol as a solvent. The ethanol extracts were then formulated into clay masks using kaolin as the base material, with ratios of 1:1, 2:1, and 1:2. The organoleptic evaluation showed no changes in color, odor, or texture of the masks during storage. All formulations were homogeneous with an average pH ranging from 5.19 to 5.97. The viscosity test results ranged from 29.14 to 37.05 Pa’s, the average spreadability was 27.12-38.90 mm, and the drying time ranged from 15.21 to 17.58 minutes. It can be concluded that the ethanol extract combination of dayak onion leaves and Siamese banjar orange peel can be formulated into a stable clay mask and all formulations meet the required physical evaluation.
PENGARUH PELATIHAN TANGGAP TUBERKULOSIS DAN PENDAMPINGAN MINUM OBAT TERHADAP PENGETAHUAN KADER KESEHATAN DESA DI KECAMATAN BLUTO Rahem, Abdul; Wijaya, I Nyoman; Ifadotunnikmah, Farida; Rahmadi, Mahardian; Achmad, Gusti Noorrizka Veronika; Athiyah, Umi; Yuda, Ana; Zulkarnain, Bambang Subakti; Nugraheni, Gesnita; Ardianto, Chrismawan; Sumarno, Sumarno; Aryani, Toetik; Budiatin, Aniek Setiya; Hermansyah, Andi; Sulistyarini, Arie; Priyandani, Yuni; Sukorini, Anila Impian
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/s8534m26

Abstract

Tuberculosis (TB) is one of the leading causes of death from infectious diseases worldwide. Indonesia ranks as the country with the second-highest number of TB cases after India. TB awareness training and medication adherence support for village health cadres are strategic steps to enhance their capacity in supporting TB treatment. This study aims to analyze the impact of TB awareness training and medication adherence support on improving the knowledge of village health cadres. A pre-experimental study with a pretest-posttest design was conducted involving 50 village health cadres in Bluto Subdistrict, Sumenep Regency. Data were collected using questionnaires administered before and after the training. Analysis was performed using the Mann-Whitney test. There was a significant increase in the knowledge scores of village health cadres regarding TB (pretest: 3.50 ± 1.65; posttest: 5.64 ± 2.70; p<0.05) and anti-TB drug side effects (pretest: 7.66 ± 4.07; posttest: 15.04 ± 3.11; p<0.05). The training also successfully enhanced the cadres' understanding of TB symptoms, prevention, and treatment, including drug side effects. TB awareness training and medication adherence support significantly improved the knowledge of village health cadres, making them more competent in supporting TB control efforts at the community level.
HUBUNGAN TINGKAT PENGETAHUAN TERHADAP KEPATUHAN PENGOBATAN PADA PASIEN TUBERKULOSIS PARU DI RSUD KAB. BEKASI Sari Dewi, Masita; Alaidarahman, Nazwa; Oktaviona, Nisa
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/156evf89

Abstract

According to information contained in the 2023 Global TB Report, Indonesia is ranked second in the country with the highest number of TB cases in the world after India. The level of knowledge and compliance is an important indicator for assessing the success of treatment in pulmonary tuberculosis patients. This factor is one of the determinants of the increase or decrease in morbidity rates for pulmonary tuberculosis. The aim  study was to determine the relationship between the level of knowledge and compliance with treatment of pulmonary tuberculosis patients at the Bekasi District Hospital. This research design a cross-sectional observational analytical descriptive approach carried out at the Bekasi District Hospital with sample of 146 respondents. Data collection used a validated knowledge level questionnaire and patient compliance with treatment used the MMAS-8 questionnaire. Data analysis was carried out with the SPSS statistical application using the chi-square test. Based on the research results, it is known that the p value (p=0.000) shows a relationship between the level of knowledge and treatment compliance in pulmonary tuberculosis patients at Bekasi District Hospital. The conclusion study is that there is a significant relationship between the level of knowledge and treatment compliance in pulmonary tuberculosis patients.
KUALITAS HUBUNGAN PELAYANAN INFORMASI OBAT TERHADAP KEPUASAN PASIEN DIRUMAH SAKIT UMUM DAERAH DAYA DAN RUMAH  SAKIT TK. II PELAMONIA KOTA MAKASSAR Febriani, Rika; Emelda, Andi; Dewi Yuliana
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/k3v76s25

Abstract

Pharmacists play an important role in providing quality drug information to patients. Good drug information services can reflect the quality of health services and increase patient satisfaction. This study aims to measure the quality of drug information services and patient satisfaction at Daya Hospital and Pelamonia Tk. II Hospital, Makassar, and to determine the relationship between the two. This study is descriptive with cross-sectional approach, involving 318 respondents in each hospital. The results showed that the quality of drug information service at RSUD Daya was good (57.23%) and at RS Tk. II Pelamonia was also good (57.54%). Patient satisfaction at RSUD Daya, using Importance Performance Analysis (IPA) method, on tangible dimension (71.42%), reliability (73.21%), responsiveness (73.38%), assurance (75.55%), and empathy (76.29%). At Tk. II Pelamonia Hospital, patient satisfaction in the dimensions of tangible (66.47%), reliability (70.77%), responsiveness (69.55%), assurance (73.74%), and empathy (72.28%). The chi-square statistical test shows a significant relationship between the quality of drug information services and patient satisfaction with a Sig value. 0.000 ≤ 0.05 in both hospitals.
ANALISIS KADAR FLAVONOID TOTAL INFUSED WATER CHIA (Salvia hispanica L.) SEED DENGAN VARIASI LAMA PENYIMPANAN SECARA SPEKTROFOTOMETRI UV-Vis Dewi Nur Istikhomah; Dhurhania, Crescentiana Emy
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.1984

Abstract

Chia Seed contains antioxidants that found in flavonoid compounds. Antioxidants play an important role in warding off free radicals that damage cells and body tissues. This study aims to determine the total flavonoid content of infused water chia seeds (Salvia hispanica L.) with variations in storage time using the UV-Vis spectrophotometric method. Qualitative analysis with HCl and Mg metal, 10% NaOH and H2SO4 reagents with positive results containing flavonoids. Quantitative analysis uses UV-Vis spectrophotometry with a stable operating time of 28 minutes and a wavelength of 440 nm. The results of determining total flavonoid levels obtained from infused water chia seeds at a variation of 12 hours of storage time was 53.237 ± 0.246726 mgQE/ 100 ml, 10 hours of storage time was 51.862 mgQE/ 100 ml, and 8 hours was 30.381 mgQE/ 100 ml. ml. With prolonged storage, a diffusion process occurs which causes flavonoid levels to increase. The One Way Anova test obtained a significant value of 0.000 < 0.05 and the Post Hoc Test obtained a significant value of 0.000 < 0.05 so it can be concluded that there are real differences between the three variables.
HUBUNGAN TINGKAT PERILAKU PENGOBATAN DENGAN KADAR GLUKOSA DARAH PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS SUNGAI MESA BANJARMASIN Novia Ariani; Aisya Novrida Putri; Riza Alfian; Maria Ulfah; Amaliyah Wahyuni; Erna Prihandiwati
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2303

Abstract

Diabetes mellitus Type 2 (DMT2) is a chronic disease that, if left untreated, can lead to complications such as macrovascular and microvascular disorders. DM is an incurable disease. The management and treatment of type 2 diabetes mellitus aim to control blood glucose levels to prevent severe complications. The purpose of this study is to examine DMT2 patient’s treatment behavior, DMT2 patient’s fasting blood glucose level, and the relationship between treatment behavior levels and blood glucose levels in type 2 diabetes mellitus patients at the Sungai Mesa Health Center in Banjarmasin. This study uses a cross-sectional design with 41 samples of type 2 diabetes mellitus patients selected through consecutive sampling technique. The results of the study showed that the treatment behavior level was dominated by the contemplation level (48.8%). Fasting blood glucose levels were dominated by uncontrolled fasting blood glucose levels (95.1%). There was no significant relationship between treatment behavior levels and blood glucose levels, with a p-value from the Spearman correlation test of > 0.05 (0.527). The conclusion of this study is that treatment behavior levels are not a major factor in controlling blood glucose levels.
PENGARUH KOMBINASI PELARUT EKSTRAKSI ETANOL 96%-ETIL ASETAT (1:1) DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.) TERHADAP PERTUMBUHAN BAKTERI Bacillus subtilis Hasani, Najwi; Muhammad Awaluddin Padjrin; Daipadli; Hayatus Sa’adah
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2306

Abstract

The leaves of Pandan Wangi (Pandanus amaryllifolius Roxb.) are known for their antibacterial properties, containing bioactive compounds such as alkaloids, flavonoids, saponins, tannins, polyphenols, essential oils, steroids, and terpenoids. This study aimed to evaluate the antibacterial activity of ethanol-ethyl acetate (1:1) extract of Pandan Wangi leaves against Bacillus subtilis using the well diffusion method. The extract was prepared through maceration, and phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, phenols, and steroids. Antibacterial activity was assessed at concentrations of 1%, 5%, 10%, 20%, 30%, 40%, and 50%. The results indicated that the extract exhibited significant antibacterial activity at concentrations of 10% and above, producing inhibition zones of 8.39 mm, 10.33 mm, 11.27 mm, 13.37 mm, and 15.57 mm for 10%, 20%, 30%, 40%, and 50% respectively. No inhibition was observed at 1% and 5% concentrations. In conclusion, the ethanol-ethyl acetate extract (1:1) of Pandan Wangi leaves demonstrated effective antibacterial activity against B. subtilis at a minimum concentration of 10%, confirming its potential as a natural antibacterial agent.

Page 30 of 34 | Total Record : 336

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