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Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 336 Documents
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PENGETAHUAN, SIKAP DAN PRAKTIK PENGGUNAAN OBAT ANTIDIABETES SECARA KONVENSIONAL DAN KOMPLEMENTER PADA PASIEN DIABETES DI RUMAH SAKIT X KOTA MALANG Rhima Diastya Amalia; Aditama, Lisa; Rahem, Abdul
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2354

Abstract

The long term diabetes mellitus treatment, encouraging patients to try alternative medicine. The Knowledge, Attitude and Practice Study has been used to determine the ability of patients in use of alternative and complementary medicine. This study aims to determine the differences in sociodemographic characteristics, knowledge, attitudes and practices between Type 2 Diabetes Mellitus (T2DM) patients who consume complementary herbal medicine and T2DM patients who consume conventional medicine. The design of this study, non-experimental cross-sectional, was conducted in August 2024 at a Hospital in Malang City. The number of respondents was 105 patients with a diagnosis of T2DM. Data were collected using questionnaires filled out independently by the patients. Data analysis used SPSS 30. The results showed no differences in sociodemographics and clinical between the two groups (p≥0,05). The knowledge of patients who use complementary herbal medicine showed more positive results, they have knowledge to not to stop conventional drugs prescribed by doctors (p=0,030). However, they have a more negative attitude in terms of choosing not to discuss with a doctor before using complementary herbal medicine (p=0,007). In practice there was a significant difference between the two groups (p < 0,001).
FORMULASI DAN UJI STABILITAS GEL MASK FRAKSI ETIL ASETAT BUNGA TELANG (Clitoria ternatea L.) SEBAGAI ANTIOKSIDAN Puspitasari, Dewi Fitriani; Utami, Rani Nur Ayu; Wildan, Achmad
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2423

Abstract

The ethyl acetate fraction of butterfly pea flower was found to have higher antioxidant activity than other fractions. This fraction can be utilized in making gel mask preparations, as an alternative to topical antioxidants. The purpose of this study was to formulate the ethyl acetate fraction in a gel mask preparation, and test the physical characteristics and stability of antioxidant activity before and after being stored for 3 months at room temperature. Extraction of telang flowers, using 70% ethanol, followed by fractionation with n-hexane, ethyl acetate and water. The results of the ethyl acetate fraction were tested for antioxidant activity, then formulated in a gel mask preparation. Evaluation of the physical characteristics of the preparation includes organoleptic test, homogeneity, pH, viscosity, adhesion, spreadability, and antioxidant activity test, before and after 3 months storage with DPPH. The results of the antioxidant activity test of the ethyl acetate fraction obtained a value of 25.14 µg/mL. The results of the physical characteristics of the gel have a pH 5.18 ± 0.035, viscosity 9541 ± 32.14 cps, adhesion 2.04 ± 0.015 seconds, spreadability 4.55 ± 0.015 cm. The antioxidant activity of the gel decreased after storage for 3 months.
EVALUASI ARAH KOMPETENSI LULUSAN PROGRAM STUDI PENDIDIKAN PROFESI APOTEKER PADA PENDIDIKAN TINGGI FARMASI DI KALIMANTAN SELATAN, INDONESIA Muhammad Reza Pahlevi; Noval; Febrianti, Dwi Rizki; Difa Intannia; Syahrizal Ramadhani; Melviani; Mustika Muthaharah
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2431

Abstract

South Kalimantan has four Pharmacy Higher Education Institutions (PTF) offering Pharmacist Professional Education Study Program (PSPPA), namely Lambung Mangkurat University (ULM), Borneo Lestari University (UNBL), Sari Mulia University (UNISM), and Muhammadiyah University of Banjarmasin (UMB). This research aims determine competency direction PSPPA graduates from PTF in South Kalimantan. Using descriptive research design qualitative case study method, the findings reveal that graduate profile PSPPA South Kalimantan does not fully reflect local and national characteristics  pharmacist, such as being religious, having national perspective, adhering professional ethics, and upholding the law. The graduate profile should encompass  institution's vision, academic excellence, moral values, specific characteristics higher education institution. PSPPA designed with min.36 credits over 2 semesters. ULM directs PSPPA competencies towards pharmaceutical practices in wetland environments, integrated into several courses. UNBL focus producing professional pharmacist with foundation Kalimantan's local wisdom, featuring integrated course pharmaceutical services. UNISM emphasizes excellence and collaboration  developing riverine potential, integrated Phytotherapy course, given South Kalimantan's, particularly Banjarmasin's, numerous river systems. Meanwhile, UMB develops PSPPA program characterized progressive Islamic value, with standout course Islamic Professionalism. The results align with graduate competency standards and pharmacist education curriculum standards  APTFI, Law No.17 of 2023, and Minister Education and Culture Regulation no.53 of 2023
KAJIAN RASIONALITAS PENGGUNAAN ANTIBIOTIK PADA PASIEN INFEKSI SALURAN KEMIH DI INSTALASI RAWAT JALAN RSUD ULIN BANJARMASIN Nazhipah Isnani; Muliyani; Khairunnisa; Muhammad Zaini; Nabila Hadiah Akbar
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2441

Abstract

Urinary Tract Infection (UTI) is in the second position as an infectious disease that often occurs in developing countries after infection in surgical wounds with a percentage of cases of 23.9%. Antibiotics are used as the main choice in the treatment of urinary tract infections, so there is a need for rational treatment measures in the use of antibiotic. Rational treatment can be achieved if it meets certain criteria. The aim of the research was determine the rationality of using antibiotik s in patients with urinary tract infections in the outpatient installation of Ulin Hospital, Banjarmasin. The research method used was descriptive quantitative with a cross sectional design using secondary data, namely medical records taken retrospectively. The results of the research carried out are that the highest use of antibiotic used to treat urinary tract infections in outpatients at Ulin Hospital Banjarmasin for the 2023 period is ciprofloxacin with a percentage of 52%, and the rationality of antibiotic based on the indication is 100% correct, the dose is 90% correct, the drug is 100% correct, the patient is 100% correct, the interval of administration is 90% correct, and the duration of administration is 90% correct.
ANALISIS DAMPAK PENERAPAN SISTEM INFORMASI MANAJEMEN RUMAH SAKIT (SIMRS) PADA EFISIENSI WAKTU TUNGGU DI POLIKLINIK ANAK Ajie, Whisnu; Simbolon, Nadya Veronica; Cahyanti, Naomi Dwi
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2486

Abstract

Waiting time is one of standards in hospitals. A waiting time of more than 30 minutes in prescription retrieval can reduce patient satisfaction. The purpose of this study was to determine the effectiveness of waiting time for prescription services after the implementation of the Hospital Management Information System (SIMRS). This research is a type of sequential explanatory design, with a combination method between quantitative methods with statistical tests and qualitative methods with interviews with pharmacy officers who use the SIMRS in the pediatric polyclinic of four people who have met the criteria “have used SIMRS for 2 years”. The results obtained, the waiting time for prescription services at the pediatric polyclinic for general prescription concoctions has met the Permenkes standard ≤30 minutes and has decreased by 10.4 minutes after implementing SIMRS. While the results for non-recipe general prescriptions have met the Permenkes standard ≤15 minutes and have decreased by 2.1 minutes after implementing SIMRS. Based on hypothesis testing, it can be concluded that there is an increase in the effectiveness of waiting time for prescription services after SIMRS is implemented for both concoction and non concoction prescriptions by looking at the significance value of the statistical test 0.00 <0.05.
Analisis Residu Pelarut Heksana Minyak Biji Bunga Matahari Dengan Teknik Mikroekstraksi Fase Padat Menggunakan Kromatografi Gas-Detektor Ionisasi Nyala Maharani, Bunga Adhelia; Hanwar, Dedi
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2489

Abstract

Penggunaan pelarut organik seperti heksana dalam proses ekstraksi minyak biji bunga matahari dapat meninggalkan residu yang berpotensi membahayakan kesehatan jika melebihi batas maksimal residu yang ditetapkan. Penelitian ini bertujuan untuk menentukan kadar residu pelarut heksana dalam minyak biji bunga matahari yang beredar di e-commerce dengan teknik Mikroekstraksi Fase Padat menggunakan Kromatografi Gas – Detektor Ionisasi Nyala. Validasi metode diuji dengan parameter linearitas, akurasi, keberulangan, batas deteksi (LOD), dan batas kuantifikasi (LOQ). Hasil penelitian menunjukkan bahwa metode SPME-GC-FID memiliki linearitas yang baik dengan nilai R2 sebesar 0,99, LOD sebesar 0,01 ppm, LOQ sebesar 0,03 ppm, %recovery 100,81%, dan nilai RSD sebesar 0,58%. Analisis sampel menunjukkan bahwa kadar residu heksana pada minyak biji bunga matahari diperoleh sebesar 3,31 mg/kg pada sampel A, 0,49 mg/kg pada sampel B, dan 2,60 mg/kg pada sampel C. Hal tersebut menunjukkan bahwa kadar residu pelarut pada ketiga sampel melebihi batas maksimal residu yang ditetapkan oleh BPOM yaitu 0,1 mg/kg.
PENERAPAN CUSTOMER SATISFACTION INDEX (CSI) DAN ANALISIS GAP PADA KUALITAS PELAYANAN KEFARMASIAN DI APOTEK KIMIA FARMA 347 PEKAYON JAWA BARAT BULAN MARET 2024 Yudha Sukowati; Umul Angga Brahmono; Herty Nur Tanty; Gerbila Sabatini
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2492

Abstract

Consumer satisfaction depends on consumer perceptions and expectations. A person's feelings of pleasure and disappointment arise after comparing perceptions of performance. Pharmaceutical service is a direct and responsible service to patients related to pharmaceutical preparations, intended to achieve definite results to improve the quality of life of patients. The purpose of this study was to determine customer satisfaction and expectations of the service performance of the Kimia Farma 347 Pekayon Pharmacy. The methods used in this research are the Customer Satisfaction Index (CSI) method and GAP Analysis. This research was conducted using a survey method, namely distributing questionnaires to pharmacy customers. Sampling using accidental sampling technique with inclusion criteria, so that a total sample of 321 respondents was obtained. The scale used is a Likert scale based on the level of satisfaction and importance. The results showed that the Customer Satisfaction Index (CSI) value of the customer satisfaction level of 81.14% was included in the very satisfied criteria. The highest gap value is 0.61 in the indicator of the officer explaining the dose/rule that the drug should be taken and the lowest gap value is 0.10 in the indicator The price of the drug can be reached by the patient.
EVALUASI STABILITAS FISIK FORMULA SEDIAAN SUSPENSI EKSTRAK TERIPANG NANAS (Thelenota ananas) DENGAN VARIASI KONSENTRASI NA CMC DAN SORBITOL Azizah Ahsaninnisa; Ahmad Fauzi
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2503

Abstract

Suspense preparation formulation of pineapple sea cucumber extract as an active substance of protein functions in improving immunity. Solubility is the basis for making oral suspension preparations. The main challenge in suspension formulation is physical stability. Problems that often occur include inadequate viscosity, sedimentation and redispersibility. This study aims to determine the physical stability of pineapple sea cucumber extract suspense preparations with varying concentrations of Na CMC and Sorbitol with physical stability parameters including organoleptical tests, pH, viscosity, sedimentation volume, and redispersion. The test results of the suspension preparation have an influence on physical stability. Meanwhile, the variation of Na CMC and sorbitol has no effect on the pH of the preparation. The seven formulas evaluated for physical stability meet the requirements for good suspense preparations from organoleptics, pH, viscosity, sedimentation volume, and redispersibility.
KOMBINASI EKSTRAK SECANG (CESALPINIA SAPPAN L.) DAN METFORMIN SEBAGAI ANTI HIPERGLIKEMIA SECARA IN VIVO Cikra Ikhda Nur Hamidah Safitri; Putri Ade Muhaimatus Solikhah
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2506

Abstract

Secang wood (Caesalpinia sappan L.) is considered one of the sources of modern medicine that may have effective hypoglycemic effects, or lowering blood sugar. This wood is rich in various phytochemicals. The aim of this study is to observe how the combination of secang bark extract and metformin acts as an antihyperglycemic in male rats. This research is an experimental study. The doses used include Secang wood extract of 285.71 mg/kg and 666.66 mg/kg, Metformin 300 mg/kg, and a combination of both in a ratio of 1:1. The test animals were divided into seven groups (each consisting of five individuals). Diabetes induction was performed using alloxan. Blood glucose levels were measured at baseline, on days 1, 3, 7, 14, and 21 after treatment. Data were analyzed using ANOVA. The results showed that the combination therapy provided a synergistic effect, marked by a highly significant decrease in blood glucose levels (p < 0.01) starting from day one, and the glucose levels returned to normal on day 21 after treatment. The administration of Secang wood extract alone has antihyperglycemic potential, and when combined with metformin, it produces a significant hypoglycemic effect.
REVIEW: PENDEKATAN TERAPI MOLEKULER PADA KANKER PAYUDARA TERHADAP PERAN EVEROLIMUS DAN TEMSIROLIMUS SEBAGAI PROTEIN KINASE INHIBITORS JALUR PI3K/AKT/MTOR Bachrudin, Panji; Sulaeman, Agus; Mulyani, Yani
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2508

Abstract

Kanker payudara merupakan penyebab utama kematian akibat keganasan pada wanita secara global, dengan prevalensi yang terus meningkat. Jalur PI3K/AKT/mTOR memegang peran penting dalam regulasi proliferasi, metabolisme, angiogenesis, dan kelangsungan hidup sel. Aberasi genetik seperti mutasi PIK3CA dan kehilangan fungsi PTEN sering dikaitkan dengan perkembangan kanker payudara dan resistensi terapi hormonal. Review artikel ini bertujuan mengulas peran protein kinase inhibitors (PKIs), khususnya Everolimus dan Temsirolimus, yang menargetkan jalur PI3K/AKT/mTOR dalam terapi kanker payudara, mencakup mekanisme kerja, efektivitas terapeutik, dan tantangan klinis. Kajian ini merupakan tinjauan literatur sistematik terhadap publikasi ilmiah nasional dan internasional selama 2015–2025, yang membahas aspek farmakologis, molekuler, dan klinis penggunaan Everolimus dan Temsirolimus. Everolimus menunjukkan efektivitas dalam kanker payudara ER-positif resisten hormon, sering dikombinasikan dengan terapi endokrin. Temsirolimus, meskipun lebih umum digunakan untuk kanker ginjal, memiliki potensi dalam terapi kanker payudara. Tantangan mencakup resistensi, efek samping toksik, serta kurangnya biomarker prediktif. Everolimus dan Temsirolimus sebagai inhibitor mTOR menawarkan pendekatan terapi menjanjikan melalui penghambatan jalur PI3K/AKT/mTOR dalam penanganan kanker payudara.

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