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Pharmaceutical And Biomedical Sciences Journal (PBSJ)
Published by Universitas Islam Negeri Syarif Hidayatullah Jakarta
ISSN : 27152979     EISSN : 27156702     DOI : https://doi.org/10.15408/pbsj
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health
Pharmaceutical and Biomedical Sciences Journal is an official peer-reviewed, open access journal that is managed by the Pharmacy Department, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta, Indonesia. This journal publishes original research articles, review articles, as well as short communications covering all aspects of Pharmacy, Pharmaceutical dan Biomedical Sciences in both Bahasa Indonesia and English. The journal includes various fields of Pharmacy, pharmaceutical and biomedical sciences such as: Pharmacology and Toxicology, Pharmacokinetics, Community and Clinical Pharmacy, Pharmaceutical Chemistry, Pharmaceutical Biology, Pharmaceutics,Pharmaceutical Technology, Biopharmaceutics, Pharmaceutical Microbiology and Biotechnology, Alternative medicines, Biochemistry& Biomedic.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 140 Documents
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Comparative Utility of Doxorubicin, Cyclophosphamide, and Docetaxel in Breast Cancer Treatment in West Sumatera. Fitria, Najmiatul; Nur Rahmadani, Intan; Permatasari, Dita; Handayani, Fitri
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 2 (2024)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i2.40914

Abstract

The large number of breast cancer cases in Indonesia and the high cost of treatment cause the need for utility analysis. West Sumatra province ranks second with the highest prevalence of breast cancer in Indonesia. This study aimed to determine the quality of life of breast cancer patients at the national referral hospital Dr. M. Djamil, West Sumatra, who underwent chemotherapy. This study used a cross-sectional design from January to April 2024. Data collection was done prospectively by filling out questionnaires at the Chemotherapy Unit. Utility value was obtained from filling out a questionnaire with the EQ-5D-5L instrument. Data were analyzed using the Mann-Whitney and Kruskal-Wallis tests. The data obtained was 47 respondents who received Doxorubicin and Cyclophosphamide chemotherapy regimen (24 respondents) and a Docetaxel chemotherapy regimen (23 respondents), all of whom met the inclusion criteria in this study. The average utility value obtained for the doxorubicin and cyclophosphamide regimes is 0.637, and the average utility value for the docetaxel regimen is 0.704. Age did not affect utility (p>0.05), while recent education, occupation, and patient origin affected utility (p<0.05). Both regimens provided similar perceived quality of life and overall health status as measured by utility and VAS scores, suggesting comparable patient-reported quality of life outcomes between these chemotherapy treatments.
Hubungan Sosiodemografi Pasien dengan Pengetahuan Pasien tentang Pelayanan Informasi Obat menggunakan Telefarmasi (E-Pharmacy) Mita Restinia; Mabrurotul Mustafidah; Rania Adhamira; Annisa Putri Kinanti
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 1 (2024)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.31900

Abstract

E-pharmacy or telepharmacy is a form of ICT-based health service that facilitates consultation with medical practitioners. Telepharmaceutical services in Indonesia have not been implemented widely. This is because ICT access has not been perfectly spread throughout Indonesia. There is also still little socialization related to telepharmaceuticals, so that the understanding of telepharmaceuticals cannot reach the public, which causes telepharmaceuticals to not being implemented properly. This study aims to determine the relationship between the sociodemographic characteristics of respondents and the level of patient knowledge of drug information services using telepharmacy. This research is a descriptive quantitative correlation research. Respondents in this study amounted to 401 people. Statistical test using Chi Square test obtained p value < 0.05 for age and education test with telepharmaceutical knowledge, which can be concluded that there is a relationship between respondent's age and education with telepharmaceutical knowledge; and p value > 0.05 for the test of gender, occupation, frequency of application use with telepharmaceutical knowledge, which can be concluded that there is no relationship between gender, occupation, frequency of application use and telepharmaceutical knowledge.
Pengaruh Praperlakuan Fermentasi Fusarium terhadap Rendemen dan Profil Kimia Hidrodistilasi Minyak Gaharu Defiza Defiza; Handaryni Ratna Ningsih; Supandi Supandi; Hendri Aldrat
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 2 (2024)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i2.42108

Abstract

Gaharu dari Aquilaria sp. telah menjadi wewangian resin alami yang berharga selama ribuan tahun, dihargai karena keunikan dan aromanya. Namun, kelangkaannya di alam liar telah mendorong strategi inovatif untuk meningkatkan produksi, mulai dari membangun perkebunan berkelanjutan hingga mengoptimalkan metode penyulingan. Penelitian ini menyajikan pendekatan untuk meningkatkan hasil gaharu melalui pretreatment fermentasi menggunakan Fusarium sp. untuk jangka waktu 1 hingga 4 minggu. Setelah itu, hidrodistilasi dan analisis komponen minyak gaharu dilakukan menggunakan GC-MS (Gas Chromatography-Mass Spectrometry). Hasil menunjukkan peningkatan rendemen gaharu, bersama dengan profil kimia yang diperkaya, yang menunjukkan efektivitas praperlakuan Fusarium sp. sebelum hidrodistilasi. Penelitian ini tidak hanya membuka jalan bagi produksi gaharu yang berkelanjutan, tetapi juga menyoroti potensi besar pemanfaatan metode alami untuk meningkatkan aroma dari produk bernilai ekonomis tinggi ini.
Combination of Beetroot Juice, Honey and Green Apple on Hemoglobin Levels in Anemia Pregnant Women at Payung Sekaki Health Center, Pekanbaru Septi Indah Permata Sari; Elly Susilawati; Shinta Devi; Berwi Fazri Pamudi
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 5, No 2 (2023)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v5i2.31539

Abstract

Anemia is a medical condition characterized by lower-than-normal hemoglobin (Hb) levels. In pregnant women, anemia can lead to prolonged delivery times, increased bleeding, and shock during contractions. The adverse effects of anemia on the fetus include premature birth, low birth weight (LBW), potential disabilities, and infant mortality. The recommended solution to overcoming anemia in pregnant women is to consume a combination of beetroot juice and green apples juice. Beets contain essential components that can elevate Hb levels, whereas green apples provide minerals and vitamin C, enhancing iron absorption (Fe). This study aimed to investigate the effect of a combination of beetroot juice and green apple juice on Hb levels in pregnant women with anemia. The study population was comprised of 200 normal pregnant women, with a sample size of 15 in trimester III (TM III) with anemia, selected through purposive sampling. The intervention involved administering the juice daily for seven days. Data were collected using observation sheets and easy-to-touch devices. The research design was pre-experimental, utilizing a one-group pre-test–post-test design. This study was conducted within the working area of the Payung Sekaki Public Health Center (PHC) from January to April 2022. Dependent T-test analysis was used for data evaluation. The average Hb level of TM III pregnant women before juice consumption was 9.7 g/dL, which increased to 10.6 g/dL after the intervention. The dependent t-test results, with a 95% confidence level (Cl), indicated a p-value of 0.000, signifying a significant impact of fruit juice on the Hb levels of TM III pregnant women experiencing anemia. These findings suggest that clinical midwives should educate pregnant women about the importance of Fe tablets and the positive influence of fruit juice on Hb levels.
Hubungan Antara Tingkat Pengetahuan dan Kepatuhan Penggunaan Obat pada Pasien Tuberkulosis di Salah Satu Puskesmas di Jakarta Pusat Maifitrianti Maifitrianti; Tuti Wiyati; Netha Apriliyanti Apriliyanti
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 1 (2024)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.38174

Abstract

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. Non-compliance with TB treatment can lead to low cure rates, high mortality rates and increased risk of recurrence. Knowledge is very important for TB patients in order to sensitize patients to be compliant in carrying out treatment. This study aims to determine the relationship between knowledge level and adherence to taking medication in TB patients at the Kemayoran District Health Center for the period July - September 2023. This study used a cross sectional method with purposive sampling technique. Respondents of this study amounted to 108 patients, 105 patients met the inclusion criteria and 3 patients met the exclusion criteria. The level of knowledge was assessed using the knowledge questionnaire and the level of compliance was assessed using the Medication Adherence Rating Scale (MARS-5) questionnaire. The relationship between knowledge and adherence was analyzed using the Spearman Rho test. The results showed that most patients had good knowledge as many as 81 patients (77.1%) and patients were compliant in taking medication as many as 75 patients (71.4%). The results of bivariate analysis showed that the level of knowledge had a significant relationship with adherence to taking medication (p<0.05) with a strong correlation value (r 0.660) and positive direction.
Analisis Hubungan Petugas Apotek Terhadap Pelayanan Informasi Obat Kontrasepsi Oral Marvel Marvel
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 1 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i1.28108

Abstract

The successful implementation of the Family Planning (Keluarga Berencana) program assists the government in developing reproductive health. The acceptors' knowledge about oral contraceptive drugs may be influenced by drug information conveyed by pharmacy staff, namely pharmacists and their assistants. Therefore, this study aimed to measure relationship between pharmacy staff and information services for oral contraceptives at the South Tangerang Regional Pharmacy using a cross-sectional design. This study used trained simulated patients. The samples surveyed were 152 pharmacies with 132 pharmaceutical technical personnel, and 20 pharmacists as respondent. In terms of drug information services, this study found 94 subjects in the poor category (value of 69.9%), 44 subjects (26.4%) in the moderate category (value between 70-79.9%), and 14 subjects (7.9%) in the good category (value of 80%). There was a significant relationship between the pharmacy staff variable with the total value of drug information services (Pelayanan Informasi Obat) variable (p = 0.016). The result showed that pharmacists provide information services for oral contraceptives better than pharmacy technicians.
Optimization Parameters of Natural Deep Eutectic Solvent Based on Choline Chloride and Fructose for Extraction of Polyphenol from Jotang (Spilanthes acmella) Stem Fajar Amelia Rachmawati Putri; Askal Maimulyanti; Isna Nurhidayati; Bella Mellisani; R. Wiwi Widarsih; Fitria Puspita; Anton Restu Prihadi
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 1 (2024)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.39583

Abstract

Natural deep eutectic solvents (NADES) have become popular as an environmentally benign alternative to conventional solvents for extracting natural compounds. In this current research, choline chloride was employed as a hydrogen bond acceptor (HBA) and was mixed with fructose which had the role of a hydrogen bond donor (HBD) to construct NADES. This extracting agent was deployed to separate the polyphenolic compounds from the stem of Jotang (Spilanthes acmella) under prime conditions. The extracted polyphenol was subsequently calculated based on the Folin-Ciocalteu method using gallic acid as the standard solution by UV-Vis spectrophotometer at 760 nm. Corresponding to the research outcomes, the most gainful states of extraction were achieved at a sample weight-to-NADES volume ratio of 1:50, a period of extracting process of 60 min, water content of 20%, and a stirring speed of 80 rpm. The optimized parameters were conceived as the most gainful because they exhibited the most prominent level of polyphenol were described as follows: ratio of sample weight-to-NADES volume and extraction time showed polyphenol content of 25.13 mg GAE/g each, while the others, stirring speed and water content revealed the polyphenol concentration of 25.75 mg GAE/g respectively.
Aktivitas Antijamur Ekstrak Biji Kopi Hijau Robusta (Coffea canephora) Terhadap Candida albicans. Ing Mayfa Br Situmorang; Putri Salsadila; Sharfina Maulidayanti; Asbar Tanjung
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 2 (2024)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i2.39149

Abstract

Acne is a disease that can be caused by bacteria, one of which is Staphylococcus epidermidis. Acne can be treated with active compounds derived from natural ingredients such as cucumbers and tomatoes. Gel masks peel off. This study aims to determine the average diameter of the inhibition zone, the difference in the average diameter of the inhibition zone, and the antibacterial activity of the peel-off from a mixture of cucumber (Cucumis sativus) and tomato  (Solanum lycopersicum) with a concentration of 5%, 10 %, 15%, 20% against  Staphylococcus epidermidis. This experimental study uses a Completely Randomized Design (CRD) consisting of one factor and 6 levels. The results showed that the average diameter of the inhibition zone of the anti-acne peel-off gel mask preparation of cucumber and tomato extracts against Staphylococcus epidermidis at a concentration of 5%, 10%, 15% and 20% were 16.38 mm, respectively. ; 24.88 mm; 29.88 mm and 34.88 mm. There was a significant difference in the average diameter of the inhibition zone of the peel off mixture of cucumber and tomato extracts with a concentration of 5%, 10%, 15%, and 20%; against Staphylococcus epidermidis. gel mask preparation peels off from a mixture of cucumber and tomato extracts against Staphylococcus epidermidis at a concentration of 5%, 10% concentration, 15% concentration and 20% concentration, namely strong, very strong, very strong and very strong.   Keywords: staphylococcus epidermidis, gel mask peel-off, cucumber, tomato
The Impact of EG and DEG Cases on Sales of Over-The-Counter Syrup Ni Nyoman Yudianti Mendra; Ni Putu Udayana Antari; Nyoman Budiartha Siada; I Gusti Ayu Marwati
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 5, No 2 (2023)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v5i2.32013

Abstract

The Indonesian Food and Drug Authority (BPOM) investigated and listed safe and unsafe syrup products in response to the contamination of Ethylene Glycol (EG) and Diethylene Glycol (DEG), causing Acute Kidney Injury in pediatric patients. Unsafe products were recalled and removed from distribution, leading to uncertainty and panic among the public and significantly impacting over-the-counter syrup sales in several pharmacies. This retrospective observational study assessed the impact of EG and DEG contamination on the sales of over-the-counter syrup in Pharmacy X in South Denpasar. Data from three months before (August to October 18th, 2022) and three months following the official instruction was published (October 19th, 2022 to December 2022) were analyzed using Wilcoxon test. The findings reveal a staggering decline in the sales of over-the-counter syrup by 35,03% (p-value of 0.03). Moreover, there was a notable increase of prescriptions in powder forms. The contamination cases caused panic, resulting in changes in behavior and consumption patterns. Despite the availability of safety information on an official website, public hesitance toward syrup products persists, indicating the need to implement a more effective strategy to address misinformation and restore public trust. Each individual must be responsible for educating the public during crises to prevent the spread of misinformation, ultimately restoring trust and normal consumer behavior. Furthermore, efficient stock management should be implemented to anticipate potential health crises in the future proactively.
Study of Consumer Satisfaction Levels with E-Pharmacy Services Using the Customer Satisfaction Index (CSI) and Importance Performance Analysis (IPA) Mabrurotul Mustafidah; Rurynta Ferly Shavira; Rania Adhamira; Annisa Putri Kinanti; Kinanti Citraningsih
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 1 (2024)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.37922

Abstract

E-pharmacy is one of the efforts to improve pharmaceutical services to make them easier and more efficient. Customer Satisfaction Index (CSI) is a scale that can describe consumer satisfaction with a product or service. Customer satisfaction with e-pharmacy services can be assessed by the value of customer expectations for service quality and the reality of the service performance received. This study aims to examine the level of consumer satisfaction, expectations, and priorities for attribute improvement in the dimensions of e-pharmacy services so that service providers can evaluate and improve their services. Furthermore, the analytical method in this study uses an analysis of the results of the gap based on the Service Quality (Servqual), Customer Satisfaction Index (CSI), and Importance Performance Analysis (IPA). The results of this study indicate that attributes' performance on the dimensions of e-pharmacy services is not satisfactory. Customer satisfaction in e-pharmacy service is 86.11% or in the 'very satisfied' category. Meanwhile, the service attribute prioritized for service providers is to improve the guarantee that the drugs given are in good condition (by showing the drug's expiration date).

Page 8 of 14 | Total Record : 140

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