Garuda - Garba Rujukan Digital

All

Proceeding of Mulawarman Pharmaceuticals Conferences

mpc
Website

Published by Universitas Mulawarman

ISSN : - EISSN : 26144778 DOI : https://doi.org/10.25026/mpc

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

LINGKUP DAN TUJUAN Lingkup naskah mencakup bidang ilmu: Kimia Farmasi Biologi Farmasi Farmakologi Teknologi Farmasi dan Farmasetika Farmasi Klinik dan Komunitas Kedokteran dan Bidang ilmu lain yang terkait Tujuan penerbitan adalah memberikan informasi ilmiah tentang perkembangan ilmu pengetahuan dan teknologi bidang Farmasi dan yang terkait

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 612 Documents

40 41 42 43 44

Formulasi dan Uji Mutu Fisik Sediaan Sabun Padat Ekstrak Kulit Bawang Merah (Allium cepa L): Formulation and Physical Quality Test for Onion Skin Extract Solid Soap (Allium cepa L) Adelya Youan Nurdiana; Elly Purwati; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Shallots are one of the many types of plants available in Indonesia. Shallots are annual plants that can grow in the highlands and lowlands. In its use, shallots produce a lot of waste in the form of skin which can be processed into solid soap preparations because they contain antibacterial properties derived from flavonoid compounds. This study aims to produce solid soap onion skin extract and test the physical quality of the preparation according to the Indonesian National Standard (SNI). The research method was experimental which consisted of making simplicia and extracting it by maceration method using 70% ethanol as a solvent. Red onion peel extract formulations were used with a concentration of 5% (Formulation 2) and 0% (formulation 1) as the control basis. Evaluation of solid soap preparations includes organoleptic observation, homogeneity testing, foaming test, pH testing. The preparation was evaluated for 4 weeks at room temperature. Data were analyzed descriptively and compared with SNI. The results of this study indicate that the soap preparation is homogeneous, has a solid texture, is light brown (formulation 1), and dark brown (formulation 2). The average pH value in formulation 1 and formulation 2 is 9. The results of the organoleptic test on solid soap preparations did not change, from the first week to the fourth week it was getting denser. The foam power test on both formulations showed the presence of foam that came out when the test was carried out. The conclusion in this study is that the physical quality of onion skin extract solid soap is in accordance with SNI and is stable for 4 weeks of storage.

Uji Aktivitas Antibakteri Ekstrak Kombinasi Umbi Bawang Tiwai dan Kulit Buah Lemon Terhadap Pertumbuhan Staphylococcus aureus dan Escherichia coli: Antibacterial Activity Test of Combination of Tiwai Onion Bulbs and Lemon Peel on the Growth of Staphylococcus aureus and Escherichia coli Adinda Niti Meilaningrum; Novita Eka Kartab Putri; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Tiwai onion (Eleutherine americana (Aubl.) Merr) is a plant that contains several groups of secondary metabolites, one of which is the alkaloid group. Lemon rind (Citrus limon) is a plant that contains more than 2.5% essential oil and hesperidin. Several classes of secondary metabolite compounds from these two plants have antibacterial activity. This study aims to determine the characteristics of the extract and the antibacterial activity of the extract combination. The extract characteristics were tested in the form of organoleptic, pH and solubility. Meanwhile, the antibacterial activity test was carried out by using the well diffusion method. The results obtained were the characteristics of the tiwai bulb extract and lemon peel in the form of organoleptic (color: blackish red and yellow, thick texture, distinctive aroma of onion bulbs and lemon peel); pH (6.4 and 4.8); solubility (soluble in ethanol, methanol and aquades) and antibacterial activity at a concentration of 12: 3 with an average of 8.75mm (S. aureus) and 7mm (E.coli); 12: 6 with a mean of 11mm (S.aureus) and 7.25mm (E.coli); 12: 8 with an average of 12.25mm (S.aureus) and 13.75mm (E.coli). It can be concluded that at a concentration of 12: 8 the combination of these extracts had the highest average inhibition zone in inhibiting the two bacteria.

Evaluasi Penggunaan Analgetik Pasca Bedah Apendisitis di Rawat Inap RSUP Fatmawati Jakarta: Analgetic Use Evaluation of Post Apendicitic Surgery Inpatients of Fatmawati Hospital, Jakarta Agas Kurnia Anugrah; Lusi Agus Setiani; Naufal Muharam Nurdin
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Appendicitis is a disease caused by vermimorphic inflammation caused by blockages in the lining of the appendix, so it is necessary to perform surgery to treat the pain caused postoperatively will give a feeling of discomfort and potential complications, therapy given to control the pain that is analgetic administration. The purpose of this study is to know the pattern of analgetic use, evacuate the pattern of analgetic use and know the effectiveness of analgetic use in patients post-surgical appendicitis at RSUP Fatmawati Jakarta Year 2019 with retrospective methods and univariate statstic test to determine the distribution of patient characteristics and distribution of analytical use then wilcoxon statistical test to know the relationship of analytical use to decrease the degree of pain. The results of the study were based on univariate methods of patients suffering from mild pain as much as (60.0%), moderate pain (40.0%) then after administered analgetic patients who do not feel pain (10,5%) mild pain (88.4%) moderate pain (1,1%), then the results of each analgetic wilcoxon test showed, that the administration of a single analgetik influences the decrease in the degree of nnyeri with the results of P-value for Tramadol, Paracetamol, and Ketorolac 0,005.

Profil Kromatografi Lapis Tipis (KLT) Ekstrak Fungi Endofit Akar Kuning (Arcangelisia flava L. Merr.): Thin Layer Chromatography (TLC) Profile of Endophytic Fungi Extract of Arcangelisia flava L. Merr. Alya Ramadhani; M Arifuddin; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Each plant contains several endophytic fungi that can produce secondary metabolites, one of which is akar kuning plants. This study was conducted to determine the profile TLC of the secondary metabolites separation from the extract of endophytic fungi of akar kuning (Arcangelisia flava L. Merr.). This research began with fermentation of the akar kuning fungi isolate for 14 days. After 14 days, the endophytic fungi biomass and PDB medium were extract by the liquid-liquid extraction method using ethyl acetate as a solvent. Fungi extracts were identified using a thin layer chromatography (TLC) method, observed in UV light of 254 nm, 366 nm and sprayed with dragendorff detection reagent and AlCl3. The identification results with eluent n-hexane: ethyl acetate (3: 1) in 7 spots with Rf values of 0.15; 0.22; 0.35; 0.56; 0.75; 0.85; and 0.95, n-hexane: ethyl acetate (1: 3) produce 6 spots with an Rf value of 0.09; 0.38; 0.67; 0.76; 0.8 ;and 0.85.

Formulasi dan Uji Mutu Fisik Sediaan Sabun Padat Ekstrak Daun Kelor (Moringa oleifera L.) : Formulation of Physical Quality Test For Moringa Leaf Extract Solid Soap (Moringa oleifera L.) Angelica Olsa Okta Rizky; Elly Purwati; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

The leaves of Moringa (Moringa oleifera L.) have the potential as a medicinal plant which can often be used as an alternative for the treatment of various diseases. Besides being able to be processed for food ingredients, Moringa leaves can also be used as an anti-cancer treatment, prevent anemia and can also inhibit the activity of bacteria and fungi. This study aims to produce solid soap for Moringa leaf extract and to test the physical quality according to the Indonesian National Standard (SNI). This research method is experimental which consists of the manufacture of simplicia and extraction using the maceration method with 70% ethanol solvent. formulation using Moringa leaf extract with a concentration of 0% (base), 3% (F1), and 5% (F2). Evaluation of the physical characteristics of solid soap includes organoleptic observation, homogeneity testing, pH test, foam power test. The preparation was evaluated for 4 weeks, the data were analyzed descriptively. The results of this study indicate that a solid soap preparation that is homogeneous, has a dense and smooth texture, has a fragrant aroma, base (white color), F1 (blackish green color), F2 (blackish green color). The average pH value on the basis, F1, F2 is 9.The organoleptic test results on base solid soap preparations, F1, F2 did not change from week 1 to 4. Base solid soap foam power test values, F1, F2 remain stable. The conclusion of this research is that the physical quality of the Moringa leaf extract solid soap meets the SNI requirements.

Pengaruh Pemberian Kombinasi Jus Buah Naga (Hylocereus polyrhizus) dan Air Rebusan Daun Kersen (Muntingia calabura) pada Penderita DM (Tipe 2): Effect of Combination of Dragon Fruit (Hylocereus polyrhizus) Juice and Kersen Leaf (Muntingia calabura) Boiled Water in DM (Type 2) Patients Aprilia Putri Firdaus; Mukti Priastomo; Hadi Kuncoro
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Diabetes mellitus is a disease characterized by an increase in blood glucose levels, which prevalence in East Kalimantan in 2018 is the third highest in Indonesia. Kersen leaves and dragon fruit are believed to regulate blood glucose levels in people with type 2 diabetes mellitus and can be used as a complementary therapy. This study aims to see the characteristics, determine the organoleptic assessment of the combination of dragon fruit juice with kersen leaves boiled water and its effect on blood glucose levels, blood pressure, heart rate, body weight, and the frequency of polyuria, polyphagia, and polydipsia in patients type 2 diabetes mellitus at Klinik Semoga Sehat Samarinda. The research method used was quasi experimental with pre-test and post-test procedures. The data obtained from the characteristics were 70% aged 50-59 years, 70% women, 50% diploma/bachelor, 60% housewives. For organoleptic assessment, it was found that 70% liked the taste, texture, aroma and color and 50% did not feel bitter. The combination of dragon fruit with kersen leaves boiled water had an effect on reducing blood glucose levels significantly (P 0.05) and there was a change in the frequency of polyuria, polyphagia, polydipsia by 80% did not urinate frequently and were not often thirsty and 90% were less hungry.

Analisis Faktor-Faktor yang Mempengaruhi Kepatuhan Penggunaan Obat Pasien Diabetes Mellitus Tipe 2 di Rumah Sakit PMI Kota Bogor: Factor Analysis That Affecting Drug Complience of Type 2 Diabetes Mellitus Patients in PMI Hospital, Bogor Astri Harsono Putri; Lusi Agus Setiani; Naufal Muharram Nurdin
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Type 2 diabetes mellitus is insulin resistance with a relative of insulin secretion disorders. The prevalence of diabetes mellitus in Indonesia in 2000 came in fourth place by 8,4 million population and in 2030 is estimated to have increased by 2,3 million. This study aims to evaluate medication adherence and factors related to adherence in type 2 diabetes mellitus. This study uses descriptive analysis design conducted in February to March 2020 with a total 60 outpatient respondents. Respondent adherence rates were measured using the Morisky Medication Adherence Scale 8 Items (MMAS 8-Items) questionnaire. The significance of the relationship between variables with respondent compliance was measured using Chi-Square. While the dominant factor influencing the respondent?s medication adherence was measured using Binary Logistic Regression. The results of the study prove that the level of adherence of people with type 2 diabetes mellitus outpatient in the Bogor City PMI is in the category of ?moderate adherence?. Bivariate analysis results showed a significant relationship between education (p value 0,041), the amount of non-diabetic drugs (p value 0,035) and the total amount of drugs (p value 0,003) with respondent adherence. The results of multivariate analysis showed that the variable total amount of drugs was the dominant factor affecting the adherence of respondent taking medication (Odds Ratio 8,350).

Formulasi dan Evaluasi Sediaan Lip Scrub dari Madu (Apis dorsata): Formulation and Evaluation of Lip Scrub Preparations from Honey (Apis dorsata) Awalia Sariningsih; Nur Masyithah Z; Fajar Prasetya
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Problems on the skin of the lips are often found such as cracked, which can be solved by routinely using lip scrubs because dead skin cells on the lips need to be excreted. Honey can be used as a moisturizer in pharmaceutical preparations because of its humecant and emollient properties. This study aims to find out if honey can be used as a lip moisturizer and find out how to formulate lip scrub preparations from optimum honey. This research method was conducted experimentally, namely testing the moisture of honey on the lips using a skin analyzer. Then the formulation of lip scrub preparations with variations in honey concentration and physical stability testing which includes organoleptic test, homogeneity, pH, and spread of preparations conducted for 28 days, in addition to being conducted irritant test preparations for 2 days in a row. The results obtained by honey moisture testing on the lips increased water content by 17.6%. The results on the organoleptic test evaluation were brown, oleum rosae smell, and sweet taste. Homogeneity test to determine the homogeneity of lip scrub preparations in the absence of clumping materials that are not dissolved. pH test obtained is a stable semi-solid lip scrub preparation that is at pH 6. Spreadability test obtained diameter of 4 cm. Based on the results of evaluation on lip scrub preparations that have good physical quality and stable in F2 with honey concentration of 6%.

Formulasi dan Uji Mutu Fisik Ekstrak Daun Binahong (Anredera cordifolia (Ten.) Steenis) sebagai Sabun Cair: Formulation and Physical Quality of Binahong Leaves Extract (Anredera cordifolia (Ten.) Steenis) as Liquid Soap Chyntia Maharani; Panji Ratih Suci; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Acne or Acne vulgaris is a problem that is often experienced at all ages, especially in adolescents. One of the causes of acne is that the polysebase ducts (oil glands in the skin and hair) become blocked and cause the production of skin oil (sebum) which becomes food for bacteria. The flavonoids contained in the leaves of Binahong (Anredera cordifolia (Ten.) Steenis) can inhibit bacterial growth. This study aims to formulate the Binahong leaf extract (Anredera cordifolia (Ten.) Steenis) into liquid soap preparation and evaluate the physical quality of the preparation. The extraction method used in this study was maceration using 96% ethanol as a solvent. Liquid soap Binahong Leaf extract (Anredera cordifolia (Ten.) Steenis) is made into four formulas, namely F0 (containing 0% binahong leaf extract), F1 (containing 2% binahong leaf extract), F2 (containing 4% binahong leaf extract), and F3 (contains 6% binahong leaf extract). The physical quality test for liquid soap preparations includes organoleptic tests, homogeneity, pH, high foam, and dispersibility. The test results of the four liquid soap formulations showed that the four formulas did not experience organoleptic changes, were homogeneous, and met the pH requirements of 9.5-11. The pH range of liquid soap that meets the SNI requirements (06-3734-2006) is 8-11, the foam height range is 25-60 mm, and the spreadability range is 3-5 cm.

Aktivitas Antibakteri Ekstrak Daun Lintut (Hemigraphis sp) Terhadap Bakteri Eschericia coli, Staphylococcus aureus, Staphylococcus epidermidis, dan Salmonella typhi: Antibacterial Activities of Lintut Leaves (Hemigraphis sp) Extract Against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, and Salmonella typhi Bacteria?s Deva Ayudhia Septiani; Wisnu Cahyo Prabowo; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Lintut plants are herbaceous plants that can grow in soft or watery soil. Research on leaf extracts against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Salmonella typhi has never been done. This study aims to determine the antibacterial activity of leaf extract against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Salmonella typhi. The research stages began with the manufacture of simplicia, the manufacture of ethanol extract of lintut leaves, the ethanol extract phytochemical screening test, and the antibacterial activity test using the well diffusion method. The study was conducted using 3 groups of concentrations of lintut leaf extract, namely 7%, 9% and 10% with ampicillin 0.1% as a positive control and aquadest as a negative control. The results of the phytochemical screening test showed that the leaf extract positively contained triterpenoids / steroids and tannins. Antibacterial activity using the well diffusion method showed that the extracts of lintut leaves with a concentration of 7%, 9% and 10% were not significantly different. The best concentration in inhibiting the growth of Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Salmonella typhi was at a concentration of 7%. The positive control used, namely ampicillin, produced a larger diameter of the inhibition zone compared to the diameter of the extract inhibition zone.

Page 42 of 62 | Total Record : 612

40 41 42 43 44

Filter by Year

2015 2023

Filter By Issues

All Issue Vol. 18 (2023): Proc. Mul. Pharm. Conf. Vol. 17 (2023): Proc. Mul. Pharm. Conf. Vol. 16 (2022): Proc. Mul. Pharm. Conf. Vol. 15 (2022): Proceeding of Mulawarman Pharmaceuticals Conferences (Proc. Mul. Pharm. Conf.) Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf. Vol. 12 (2020): Proc. Mul. Pharm. Conf. Vol. 12 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 11 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 9 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 8 (2018): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 7 (2018): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 6 (2017): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 5 (2017): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 4 (2016): Proceeding of Mulawarman Pharmaceuticals Conferences (Prosiding Seminar Nasional Kefa Vol. 3 (2016): Proceeding of Mulawarman Pharmaceuticals Conferences (Prosiding Seminar Nasional Kefa Vol. 3 (2016): Spesial Issue of Mulawarman Pharmaceuticals Conference Proceeding (Prosiding Semnas T Vol. 2 (2015): Proceeding of Mulawarman Pharmaceuticals Conferences (Prosiding Seminar Nasional Kefa Vol. 1 (2015): Proceeding of Mulawarman Pharmaceuticals Conferences (Prosiding Seminar Nasional Kefa More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

Phone
+6285222221907

Journal Mail Official
admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Rolan Rusli

Contact Email rolan@farmasi.unmul.ac.id

Phone +6285222221907

Journal Mail Official admin@farmasi.unmul.ac.id

Editorial Address Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location Kota samarinda, Kalimantan timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

Phone
+6285222221907

Journal Mail Official
admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA