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Proceeding of Mulawarman Pharmaceuticals Conferences

mpc
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Published by Universitas Mulawarman

ISSN : - EISSN : 26144778 DOI : https://doi.org/10.25026/mpc

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

LINGKUP DAN TUJUAN Lingkup naskah mencakup bidang ilmu: Kimia Farmasi Biologi Farmasi Farmakologi Teknologi Farmasi dan Farmasetika Farmasi Klinik dan Komunitas Kedokteran dan Bidang ilmu lain yang terkait Tujuan penerbitan adalah memberikan informasi ilmiah tentang perkembangan ilmu pengetahuan dan teknologi bidang Farmasi dan yang terkait

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 612 Documents

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Potensi Seduhan Daun Pepaya (Carica papaya L.) Kombinasi Madu Terhadap Intensitas Nyeri Haid (Dysmenorrhea) pada Wanita: Potential Infusion of Papaya Leaves (Carica papaya L.) combined with honey Against the Intensity Menstrual Pain (Dysmenorrhea) in Women Pakendek Fefryani; Nur Masyithah Zamruddin; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Menstruation is a sign that a teenager has entered puberty. Menstruation can cause pain or cramping called dysmenorrhea. In this study, 1 papaya leaf (Carica papaya L.) was used combined with 30 ml of honey. The purpose of this study was to determine the effectiveness of steeping papaya leaves (Carica papaya L.) combined with honey on the intensity of menstrual pain in women. In this test, 2 groups were used, namely the positive test and control using the Quasi Experimental research method by looking at the potential of herbal preparations on the NRS (Numerical Rating Scale) scale sheet given before and after treatment. Based on the results of the study, it was found that the effectiveness of papaya leaf tea with a combination of honey before and after administration to reduce the intensity of pain felt in each subject was significant, namely 0.000 (p <0.05) from the two treatment groups, namely the test and positive control, the comparison of pain was obtained from the leaves. papaya combined with honey was better and more effective in reducing dysmenorrhea pain after NSAIDs with a test mean ratio of 11.70 and positive control 9.30.

Uji Antelmintik dari Ekstrak Etanol Daun Kadamba (Mitragyna speciosa): Anthelmintic Test of Ethanol Extract of Kadamba Leave (Mitragyna speciosa) Putri Natasya Magdalena; Juniza Firdha Suparningtyas; Islamudin Ahmad
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Diseases caused by parasites, especially worms in animals on farms, are one of the problems that farmers often face. Worm disease can decrease the productivity of livestock and cause a decrease in the selling value of livestock at the market. The most common worm disease that attacks livestock is Paramphistomum sp. The treatment of this disease uses nutritious plants, which is one of the alternatives chosen to minimize side effects due to the administration of synthetic drugs. Kadamba leaf was chosen in this study because one of the medical plants that have potential compounds as anthelmintics. The aim of this research is to know the anthelmintic activity of kadamba leaf extract to Paramphistomum sp. 210 samples of Paramphistomum sp. were taken from cow rumen at Tanah Merah slaughterhouses. This study was conducted in vitro with seven experimental groups consisting of one positive control (Albendazole), one negative control (NaCl), and five groups of kadamba leaf extract with concentrations of 2,5%, 5%, 7,5%, 10 %, 12,5% with three replications. The results of the study showed the yield of kadamba leaf extract was 13,88%, and the anthelmintic test showed that kadamba leaf extract had anthelmintic activity against Paramphistomum sp. at all concentrations.

Formulasi Sediaan Liniment Aromaterapi dari Minyak Atsiri Bunga Kenanga (Cananga odorata): Formulation of Liniment Aromaterapy of Essential Oil Cananga Flower (Cananga odorata) Ragil Sekar Ayuni; Dewi Rahmawati; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Cananga essential oil has potential as an antidepressant and a relaxant for the nervous system, containing a compound, namely linalool from the monoterpene. The innovation of topical pharmacy preparations with the active ingredient of cananga essential oil is a useful. The purpose of this study was to formulate cananga essential oil with concentrations used of 1%, 2% and 4%. The results showed that formulas I, II and III had met the physical quality evaluation. The results of the organoleptic test of the three formulations were in the form of a liquid, a characteristic odor of cananga flower along with eucalyptus oleum and a light yellow color. The results of the pH stability test obtained an average of 4.2 formulations, 4.9 formulations II and 5 formulations III. The homogeneity test results from formulations I, II and III obtained homogeneous results. The results of the anti-irritation test of formulations I, II and III did not cause irritation. The overall results of the preference test showed that the panelists preferred the liniment preparation at a concentration of 4%. Concluded that the formulation of liniment with the active ingredient of cananga essential oil produced preparations that met the physical characteristics and hedonic tests.

Kajian Efektivitas Pengobatan pada Pasien Stroke Iskemik di Instalasi Rawat Inap RSUD Nunukan: Study of Treatment Effectiveness in Ischemic Stroke Inpatients Instalation Nunukan Hospital Rida Wahda Maulida Tahir; Hifdzur Rashif Rija’i; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Ischemic stroke occurs due to obstruction of the blood vessels that supply the brain. Obstruction occurs due to increased fat lining the blood vessels or atherosclerosis. Atherosclerosis will cause cerebral thrombosis and cerebral embolism. This study aims to examine effectiveness of the use of drugs in ischemic stroke patients hospitalization at Nunukan Hospital. This study is a non-experimental study with a descriptive analysis design using medical record data collected retrospectively and the number of samples in this study was 70 patients. The sample selection of this research was using purposive sampling technique. The results showed tthe highest characteristics of ischemic stroke patients by gender were male (54.29%), based on age group 45-65 years (64.29%), based on diagnoses with comorbidities (64.70%), and the length of treatment the most occurred in 5-10 days (72.55%). The most used drugs single therapy for ischemic stroke are antiplatelet drugs, namely aspirin (28.57%) and the most used combination therapy is piracetam and citicoline (50%). The most frequent drug interactions were aspirin and clopidogrel (48.57%). While the accuracy of drug use includes the right indication (100%), the right drug (94.29%), the right dose (97.14%), and the right frequency (97.14%). Thus, it was concluded that the treatment of ischemic stroke at the inpatient installation the Nunukan General Hospital was effective.

Karakteristik Pasien Terkonfirmasi Coronavirus disease (COVID-19) di RS X Samarinda Periode Maret-Desember 2020: The Characteristics of Confirmed Patients Coronavirus disease (COVID-19) at RS X Samarinda in March-December 2020 Ridha Siti Ruhama; Febrina Mahmudah; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Coronavirus disease (COVID-19) is a virus that has become a world pandemic including Indonesia. East Kalimantan is a province with a total of 71,092 confirmed cases of covid-19 as of March 28, 2020. The RS X Samarinda has 660 confirmed cases covid-19 during march - December period in 2020. This research aims to identify characteristics of patients covid-19 at RS X Samarinda in March - December 2020. This research is descriptive by retrospective methods. Data collection is conducted quantitatively with a sampling technique. Research instruments are 100 data inclusions of patient medical records. The results of this research show that the dominant 51% are male and 49% are female. The most age groups 34% in the early aged (46-55 years old), with further treatments >7 days as much as 65%. Patients who have 31% komorbides and without comorbidity as much as 69% in the category 87.09% diabetes mellitus. Patients data of 58,82% experienced one of the clinical symptoms of coughing/sniffles/throat pain.

Isolasi dan Karakterisasi Kitosan dari Limbah Cangkang Kerang Asia (Corbicula fluminea): Isolation and Characterization of Kitosan from Asian Shell Waste (Corbicula fluminea) Rizki Noor Amelia; Fika Aryati; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Chitosan is a substance contained in shellfish that is the most biopolymer after cellulose. The study aims to determine the best yield of chitosan results of Asian shell isolation (Corbicula fluminea) based on variations in Sodium hydroxide concentration and length of deacetylation process, and to find the characteristics of chitosan isolation results based on International Standards. The process of chitosan isolation goes through several stages, namely deproteination using a solution of Sodium hydroxide 3,5% at a temperature of 65°C for 2 hours, demineralization using a solution of Hydrochloric acid 1N at a temperature of 65°C for 2 hours, and the stage of deacetylation that is optimized with variations in Sodium hydroxide concentration of 40%, 50%, and 60% and variations in the length of stirring time of 30, 60, and 90 minutes. The results showed the best chitosan yield of 90,1% obtained from the deacetylation process using a Sodium hydroxide concentration of 60% with a stirring time of 60 minutes. The resulting chitosan characteristics are white powder, odorless, soluble in 2% acetic acid, and has a water content of 0%.

Kajian Konsentrasi Ekstrak Etanol Daun Karamunting (Melastoma malabathricum L) dalam Sediaan Krim terhadap Sifat Fisik dan Aktivitas Antioksidan: Study of Karamunting Leaves (Melastoma malabathricum L) Ethanol Extract Concentration in Cream Formulation on Physical Properties and Antioxidant Activity Rohani Rohani; Dewi Mayasari; Laode Rijai
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Karamunting leaves (Melastoma malabathricum L) have been widely used in traditional medicine due to various pharmacological activities related to its secondary metabolites, namely, flavonoids and tannins. The general objective of this research is to obtain the concentration of ethanol extract of karamunting leaves in a cream formulation that gives excellent physical properties and has antioxidant activity. The result showed extract antioxidant activity was in a very strong category with an IC50 value of 6,927 ppm. Cream with the best antioxidant activity in this study was F3 (3%) because it had the highest antioxidant activity in a strong category with an IC50 value of 60.38 ppm and had the best physical properties compared to F0 (negative control), F1 (1%), F2 (2%), and F4 (vitamin E). The freeze-thaw physical stability test showed that all formulas F0, F1, F2, F3, and F4 had good physical stability, namely, the physical properties did not differ significantly between before and after freeze-thaw for 5 cycles (p>0.05).

Efektivitas Nutrisi Medik Berbahan Aktif Mengkudu dan Apel Manalagi Terhadap Penurunan Kadar Glukosa Darah: Efficacy of Medical Nutrition using Active compounds of Noni and Manalagi Apples to Reduce Blood Glucose Levels Selfia Selfia; Muhammad Faisal; Niken Indriyanti
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Noni (Morinda citrifolia L.) contains saponin compounds that work to stimulate insulin secretion from ?-pancreatic cells and manalagi apples (Malus sylvestris Mill.) contain pectin which functions to delay the emptying of food in the stomach, bind fatty acids and reduce macronutrient absorption which can cause decreased blood glucose levels. This study aims to prove that medical nutrition with active ingredients of noni and manalagi apples has effectiveness in reducing blood glucose levels, prove that doses of medical nutrition with active ingredients of noni and manalagi apple are effective for lowering blood glucose levels and prove a decrease in blood glucose levels 30 minutes after treatment. The research method used is quasi-experimental with the measurement of blood glucose levels pre-test and post-test using human test subjects. The research ethics protocol has been obtained with No. 71/KEPK FFUNMUL/EC/EXE/08/2021 from KEPK FF UNMUL. The results showed that the administration of medical nutrition with a dose of 126 g of noni and 200 g of manalagi apple and a dose of 63 g of noni and 100 g of manalagi apple was effective in reducing blood glucose levels, with an average decrease in blood glucose levels of 9,60 ± 7,47 mg/dL and 6,40 ± 3,91 mg/dL. It can be concluded that the most effective dose to reduce blood glucose levels is medical nutrition with a dose of 126 g of noni and 200 g of manalagi apples.

Optimasi Konsentrasi VCO Terhadap Stabilitas Fisik Facewash dan Uji Antibakteri Ekstrak Daun Kelapa Sawit (Eleais Guineensis Jacq.) pada Bakteri Penyebab Jerawat: Optimization of VCO Concentration on Physical Stability of Facewash and Antibacterial Test of Oil Palm Leaf Extract (Eleais Guineensis Jacq.) on Acne-causing Bacteria Selin Cenora Aritonang; Wisnu Cahyo Prabowo; Angga Cipta Narsa; Riski Sulistiarini; Helmi Helmi
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Palm oil leaves (Elaeis guineensis Jacq.) is a waste from oil palm plantations which contain flavonoid, steroid, and alkaloid compounds that function as an antibacterial that causes acne. The purpose of this research was to identify determine the concentration of ethanolic extract of oil palm leaves which is effective in inhibiting acne-causing bacteria and to determine the best formulation that can produce a facewash base that fulfill the requirements for stability of the preparation according to SNI. Antibacterial test of oil palm leaf extract was using the pitting method against acne-causing bacteria. The results of the antibacterial test showed that the extract concentration of 75% had antibacterial activity against the growth of acne-causing bacteria. The facewash base was obtained by varying the VCO with concentrations of 17.5%, 20%, and 22.5%. The results of the evaluation of the facewash base formula for 28 days, namely F2 (20%) produced good characteristics and stability, namely a distinctive aroma, cream color, semi-solid form, pH 6,25 – 6,37, viscosity 0,904 -2,700 Pa.s, high foam stability. 89% - 100% and good homogeneity. The three base formulas have fulfill requirements for facewash according to SNI.

Kajian Potensi Interaksi Obat pada Pasien COVID-19 di Rumah Sakit X Kota Samarinda: Study of Potential Drug Interactions in COVID-19 Patients at Hospital X Samarinda City Shofia Siza Maulidia; Febrina Mahmudah; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by a coronavirus known as SARS-CoV-2 and is currently a worldwide pandemic. Treatment management for COVID-19 patients is grouped based on the level of symptoms experienced by the patient. The use of large amounts of drugs (polypharmacy) in COVID-19 patients with moderate and severe symptoms can increase the possibility of drug interactions. This study aims to determine patient characteristics and the potential for drug interactions in COVID-19 patients at Hospital X Samarinda City. The data collection method was conducted retrospectively based on the medical records of COVID-19 patients hospitalized from March to December 2020. Data on potential drug interactions were analyzed using the Drugs.com application. The results showed that of the 30 patients with COVID-19, male-dominated (60%) and aged between 46 and 55 years (50%). Data on potential drug interactions showed that 28 out of 30 patients had the potential to experience drug interactions in the categories of severe (9,23%), moderate (74,62%), and mild (16,15%).

Page 50 of 62 | Total Record : 612

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Contact Name Rolan Rusli

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Editorial Address Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

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Abstract

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Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

Phone
+6285222221907

Journal Mail Official
admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA