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INDONESIA
Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 12 Documents
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Search results for , issue "Vol 9 No 1 (2022): Jurnal Farmanesia" : 12 Documents clear
EFEKTIVITAS ANTI-AGING DALAM SEDIAAN SERBUK MASKER WAJAH DENGAN KOMBINASI AMPAS TAHU - KOLANG KALING Lubis, Minda Sari; Ayuningrum, Annisa; Rahmi, Sofia; Zulhij, Fizrya
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3423

Abstract

Ampas tahu dapat dimanfaatkan sebagai kosmetika. Ampas tahu memiliki senyawa yang hampir sama dengan hormon esterogen yaitu senyawa isoflavon yang terbukti dapat berperan sebagai antioksidan alami dalam mengurangi proses penuaan dini. Serbuk kolang-kaling dapat diformulasikan sebagai sediaan masker. Kandungan pektin yang terdapat pada kolang-kaling dapat menjaga kelembaban kulit, membantu proses peremajaan kulit dan dapat membantu proses pengelupasan atau pengangkatan sel kulit mati. Tujuan penelitian ini adalah untuk mengetahui efektivitas anti-aging dalam sediaan serbuk maser wajah kombinasi ampas tahu dan kolang-kaling dan untuk melihat perbandingan ampas tahu dan kolang-kaling yang paling efektif sebagai anti-aging
ANALISIS BIOAUTOGRAFI DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN MENGKUDU (Morinda citrifolia L.) TERHADAP BAKTERI Propionibacterium acne Nasution, Haris Munandar; Situmorang, Rati Satri
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3424

Abstract

Noni or (Morinda citrifolia L.) contains active anthraquinone, scaloptin, flavonoid, and adaptogen compounds that have antifungal and antimicrobial effects. Antibacterial chemicals have many negative side effects, and other alternatives are needed as antibacterials, one of which is by using noni. This study aims to analyze bioautography and determine the antibacterial activity of noni leaf ethanol extract against Propionibacterium acne bacteria.
STUDI LITERATUR: DAUN BIDARA (ZIZIPHUS MAURITIANA) SEBAGAI HERBAL INDONESIA DENGAN BERBAGAI KANDUNGAN DAN EFEKTIVITAS FARMAKOLOGI Wahyudi, Wahyudi; Hsb, Humaira Luthfia Putri; Hasanan, Nur; Sitorus, Rifqy Al-Hafidz
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3425

Abstract

Plants with various varieties can be found in various regions in Indonesia. Many varieties of medicinal plants in Indonesia have been used as raw materials to manufacture drugs. Some of these plants have been clinically evaluated for their phytochemical composition, efficacy, and safety to use. Bidara leaves, scientifically known as Zizhipus mauritiana L., are often used in Traditional Chinese Medicine to treat several ailments, such as urinary problems, indigestion, fever, liver complaints, weakness, anemia, obesity, diabetes, bronchitis, skin infections, loss of appetite, eating, pharyngitis, diarrhea, cancer, and insomnia. Reference libraries obtained from the search results are then studied and examined to determine research findings, then described using data or samples collected. From research and literature studies, bidara leaves have many uses, namely, as an anti-microbial agent, an analgesic, antipyretic, anti-inflammatory, and anti-cancer, and can protect body cells such as the kidneys and brain from oxidative stress, which can cause cancer.
INDENTIFIKASI SENYAWA EKSTRAK UMBI GARUT DAN TEPUNG IKAN LELE DUMBO MELALUI UJI FITOKIMIA SEBAGAI IMUNOSTIMULAN PADA TIKUS PUTIH YANG DI INDUKSI VAKSIN HEPATITIS B Zulkifli, Zulkifli; Jamil, Kurnian Fitri; Darmawi, Darmawi; Usman, Said
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3426

Abstract

The variety of biodiversity that grows in Indonesia makes this country the second megacenter in the world after Brazil. More than 30,000 plant species grow and 2,500 of them are medicinal plants one of them is arrowroot (Maranta arundinacea) as well as natural sources of animal wealth such as Dumbo catfish (Powder Clarias gariepinus) which is a source of protein that is needed by the body. Several researchers have also investigated the active compounds contained in the two ingredients, but differences in the environment and the maintenance process significantly affect the chemical content. This research focused on the initial phytochemical test and chemical composition of Maranta arundinacea extract and Clarias gariepinus powder extracted with 40% ethanol by maceration and hydrolysis techniques
ANALISIS KADAR KALSIUM PADA CANGKANG TELUR BEBEK (Anas platyrhynchos-domesticus) UNTUK PEMBUATAN PASTA GIGI DENGAN PEWARNA ALAMI DARI SARI DAUN PANDAN (Pandanus amaryllifolius Roxb) Dalimunthe, Agusmal; Nurbaya, Siti; Priltuis, Natanael; Ginting, Pitalokasari br
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3427

Abstract

Cangkang telur merupakan limbah rumah tangga yang dapat dimanfaatkan dalam pembuatan pasta gigi karena mengandung kalsium karbonat (CaCO3) sekitar 90 % sebagai penyusun utamanya. Daun pandan merupakan zat pewarna alami yang sering digunakan dalam kehidupan sehari-hari. Penelitian ini dilakukan dengan menentukan kandungan kalsium karbonat terlebih dahulu kemudian menentukan kadar kalsium murni dari kalsium karbonat tersebut dengan cara titrasi kompleksometri denga menggunakan EDTA untuk pembuatan pasta gigi dengan pewarna alami dari sari daun pandan.
UJI EFEKTIVITAS SEDIAAN GEL EKSTRAK BIJI KELENGKENG (Dimocarpus longan Lour.) SEBAGAI OBAT LUKA BAKAR TERHADAP MENCIT PUTIH JANTAN (Mus musculus) Sitorus, Elly; Thaib, Cut Masyithah; Suryani, Monica; Sarumaha, Vivid Angelina
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3428

Abstract

Longan seeds contain corrilagin, gallic acid, and ellagic acid compounds which have the potential as an alternative medicine for burns. This study aims to determine the effectiveness of the longan seed extract gel preparation with 3 variations of extract concentration (5%, 7.5%, and 10%) as a burning medicine against white male mice. Longan seed extract was obtained by using the maceration extraction method
RESISTENSI OBAT PADA PASIEN TUBERKULOSIS PARU DI PUSKESMAS BATU HORPAK KABUPATEN TAPANULI SELATAN Hutauruk, Dumartina; Situmorang, Manahan; Supartiningsih, Supartiningsih; Sitompul, Hestin Novalina
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3429

Abstract

Tuberculosis (TB) is an infectious disease with a very high prevalence in several countries in the world. Inadequate TB treatment can cause tuberculosis bacterial resistance to OAT (Anti-Tuberculosis Medicine). The emergence ofresistance M. tuberculosis can be in the form of single drug resistance (DR-TB) or a number or all of the first-line OAT (Multidrug Resistance Tuberculosis). The purpose of this study was to determine drug resistance factors which are influenced by patient habits, medical history, drugs, and health services. This type of research is qualitative research with a case study approach method. There were 6 informants in this study who were two MDR-TB patients, two patient personal monitors, a doctor, and the person in charge of the tuberculosis section. The results showed that the patient had a smoking habit and had a previous history of tuberculosis. In terms of treatment, patients do not routinely take medicines while in health services, the puskesmas have run them well so that there are no mistakes in management. The conclusion of this study is that smoking habits, previous history of tuberculosis disease, and not routine treatment are factors that greatly influence the occurrence of resistance
UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUNGA KECOMBRANG (Etlingera elatior) TERHADAP PERTUMBUHAN BAKTERI Salmonella thypi Nasution, Pandapotan; Marpaung, Jon Kenedy; Suharyanisa, Suharyanisa; Sitanggang, Rolastri
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3430

Abstract

Kecombrang (Etlingera elatior) is a type of spice that has long been known and used by humans as medicine. Kecombrang flower parts contain several chemical compounds, namely: alkaloids, flavonoids, and saponins. In addition, kecombrang flowers can also inhibit the growth of Salmonella typhi bacteria. This study aims to determine the concentration of ethanolic extract of kecombrang flower (Etlingera elatior) which is effective in inhibiting the growth of Salmonella typhi bacteria. The research sample was Kecombrang Flowers purchased at the Tarutung traditional market. This research was carried out experimentally including sampling, drying simplicia, maceration using 70% ethanol solvent, making extracts made using a rotary evaporator, and testing the antibacterial activity of kecombrang flowers using the disc diffusion method. Data analysis was conducted to see the effect of kecombrang flower ethanol extract on the activity of Salmonella typhi bacteria. The results of the study found that the results of phytochemical screening showed simplicia and ethanol extract of kecombrang flower leaves contained alkaloids, flavonoids, and saponins. While the results of the antibacterial activity test of the ethanolic extract of kecombrang flower leaves have antibacterial properties against Salmonella typhi at extract concentrations of 45%, 50%, 55%, and 60% with inhibition zone diameters of 9.4 mm, 12.2 mm, 14.8 mm, respectively. , 16.3mm. The most effective concentration of ethanol extract to inhibit the growth of Salmonella typhi was at a concentration of 60% with a larger inhibition zone diameter of 16.3 mm.
ANALISIS FAKTOR YANG MEMPENGARUHI PERTUMBUHAN KULTUR SEL CHO (Chinase Hamster Ovarium) PADA PEMBUATAN OBAT TRASTUZUMAB DI PT. BIO FARMA Silitonga, Maringan; Chandra, Devina; Fitri, Raissa; Nanda, Farahlina
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3431

Abstract

This study examines what factors can affect the growth of CHO cell cultures which are often used in biological and medical research and commercially in the production of therapeutic proteins. The purpose of this study was to determine whether CHO cells were able to grow and reproduce with the process flow and manufacturing method of drug preparations in accordance with the requirements of the applicable legislation. The workings of this research are divided into two stages, namely the microbiological stage and the biotechnology stage. The microbiological stage begins with making a working culture, then purification is carried out for culture rejuvenation, harvesting, cell culture breakdown, and purification of target cells. At the biotechnology stage, protein measurements were carried out, Optical Density 600 observations, polyacrylamide gel SDS electrophoresis, and gel electrophoresis staining.
STANDARISASI MANAJEMEN PENGELOLAAN OBAT DI INSTALASI FARMASI RUMAH SAKIT UMUM DAERAH Girsang, Vierto Irennius; Maharani, Maharani; Sinaga, Janno; Purba, Ivan Elisabeth
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3432

Abstract

Medicine management is a cycle in providing medicines which has four stages: selection, planning and procurement, distribution, and use. The objective of the research was to find out the standardization of medicinal managementin the IFRS of RSUD H. Sahudin, Kutacane, Aceh Tenggara regency. Quantitative and qualitative data were gathered from observation on documents and inteviews with IFRS personal. All stages of medicine management in the IFRS were measured by using an indicator of Depkes and WHO and compared with the result of the research. The results of the study showed that the drug management system according to the standard drug selection stage was in accordance with the standards set by the Ministry of Health of the Republic of Indonesia (2008). The planning stage has not met the standards set by WHO. The procurement stage has not met the standards set by the Indonesian Ministry of Health (2008). The distribution stage has not met the standards set by WHO (1993). The use stage has not met the standards set by WHO (1993). In order to increase the knowledge of officers about the calculation of drug management standards in hospitals.

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