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LPPM Universitas Sari Mulia Gedung D Lantai 1 JL. Pramuka No. 02 Banjarmasin Kelurahan Pemurus Luar Kecamatan Banjarmasin Timur Kota Banjarmasin Kalimantan Selatan Indonesia
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Kota banjarmasin,
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INDONESIA
Journal of Pharmaceutical Care and Sciences
Published by Universitas Sari Mulia
ISSN : -     EISSN : 28284828     DOI : https://doi.org/10.33859/jpcs.
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Journal of Pharmaceutical Care and Sciences published by the LPPM Sari Mulia UniversityPharmacy department of Sari Mulia University offers a forum for publishing the original research related to pharmaceutical science and clinical research. our focus and scope are Pharmaceutical Technology, Pharmacology & Toxicology, Drug Delivery Development, Pharmacokinetic & Biopharmaceutics, Pharmacoeconomy, Pharmacoepidemiology, Pharmacovigilance, Clinical Pharmacy, Community Pharmacy, Chemical Pharmacy, and Chemical Analysis.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 162 Documents
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D Penetapan Kadar Flavonoid Total Ekstrak Daun Kapuk Randu (Ceiba pentandra (L.) Gaertn) berdasarkan Tingkatan Fraksi: Penetapan Kadar Flavonoid Total Ekstrak Daun Kapuk Randu (Ceiba pentandra (L.) Gaertn) berdasarkan Tingkatan Fraksi Hesty Wulandari; Rohama Rohama; Putri Vidiasari Darsono
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.210

Abstract

Background: Kapok leaf (Ceiba pentandra (L.) Gaertn) is a plant that grows a lot in Central Kalimantan which is empirically used as an inhibitot of kidney stone formation and can shed kidney stones. Kapok leaves are known to contain flavonoids that can inhibit formation and dissolving kidney stones. Objective: To determine the total flavonoid content of kapok leaf extract in the n-hexane, ethyl acetat and methanol fractions. Methods: Observational descriptive method by looking at the results of the data, qualitative by using color reaction test and thin layer chromatography (TLC) and quantitative data by using UV-Vis spectrophotometry to see the total levels of flavonoids. Results: The result of qualitative analysis of flavonoid compounds with color reactions and TLC showed that they contained flavonoid compounds positive. The results of quantitative analysis using UV-Vis spectrophotometric showed that the total flavonoid content in the ethanol extract 96%, n-hexane fraction, ethyl acetate fraction and methanol fraction respectively were 31,663 mg QE / g or 3,1667%; 5,167 mg QE / g or 0,5167%; 51,833 mg QE / g or 5,1833%; and 7,166 mg QE / g or 0,7166%. The highest total flavonoid content was in the ethyl acetate fraction. Conclusion: The kapok leaf extract with the fraction level contains flavonoid compounds with total flavonoid content in the ethanol extract 96%, n-hexane fraction, ethyl acetate fraction and methanol fraction respectively were 31,663 mg QE / g or 3,1667%; 5,167 mg QE / g or 0,5167%; 51,833 mg QE / g or 5,1833%; and 7,166 mg QE / g or 0,7166%.
P Pengaruh Budaya Terhadap Penggunaan TOGA (Tanaman Obat Keluarga) Di Masyarakat Desa Terombongsari: Pengaruh Budaya Terhadap Penggunaan TOGA (Tanaman Obat Keluarga) Di Masyarakat Desa Terombongsari Diah Vinalisa Hasna Shofia; Iwan Yuwindry; Faisal Rahman
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.211

Abstract

Background: Terombongsari Village community is very much using TOGA (Family Medicinal Plants) as therapy independently. The people there tend to prefer TOGA over synthetic treatment, apart from minimal side effects, TOGA is also easy to get in people's homes. The community decides to do self-medication is influenced by several factors, one of which is culture. Culture is defined as a hereditary habit that occurs in the Terombongsari village community. Objective: This study aims to analyze the influence of culture on the use of TOGA in the Terombongsari Village community. Methods: This research uses analytical observational research with cross sectional research design. The sample is adults aged at least 17 years, totaling 92 families who routinely use TOGA. Sample selection by purposive sampling method. Collecting data with a questionnaire sheet, the data were analyzed using the Kendall tau-b test with a 95% confidence level. Results: The results show that 79.3% of the culture of using TOGA in the Terombongsari Village community is positive. The results in the use of TOGA are in the good category as much as 90.2%. The results of the bivariate analysis obtained a p-value of 0.0001, which means Ha is accepted. Conclusion: There is a cultural influence on the use of TOGA in the community of Terombongsari Village.
H Pendekatan Health Belief Model (HBM) Untuk Menganalisis Kepatuhan Pasien Diabetes Mellitus Dalam Menggunakan Insulin Di Kota Banjarmasin: Pendekatan Health Belief Model (HBM) Untuk Menganalisis Kepatuhan Pasien Diabetes Mellitus Dalam Menggunakan Insulin Di Kota Banjarmasin Sariyasih Sariyasih; Iwan Yuwindry; Erlina Syamsu
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.213

Abstract

Background: Health Belief Model (HBM) is a theory used to understand health attitudes and behavior towards a disease, HBM consists of perceived vulnerability factors, perceived severity, perceived benefits, perceived barriers, and triggers to move. Efforts to prevent the spread of the covid-19 virus in Indonesia are carried out by establishing regulations to vaccinate covid-19, especially for the elderly who are susceptible to infection with a vaccination coverage of 70% to achieve Herd Immunity. Objectives: To determine the perception of vulnerability, perceived severity, perceived benefits, and perceived barriers in influencing the elderly's perception of receiving covid-19 vaccination in Tanah Bumbu Regency. Methods: This research is a cross sectional with the type of research used is quantitative. The sampling method was purposive sampling technique and the instrument used in the study was a questionnaire with google form. The data analysis used was Univariate, Bivariate with Chi Square, and Multivariate with logistic regression. Results: The study showed that from 120 elderly respondents in Tanah Bumbu Regency, 65.8% of the elderly stated that they would vaccinate against covid-19. The dominant factor in influencing vaccination is the perception of barriers, namely the high possibility of infection in the near future. Perceived susceptibility, severity, benefits and barriers have an influence on the acceptance of vaccination in the elderly in Tanah Bumbu. Demographic factors (age, gender, occupation, education, religion, whether or not a chronic disease was diagnosed) did not have a significant influence on the acceptance of the covid-19 vaccine in Tanah Bumbu Regency. Conclusion: 65.8% of the elderly in Tanah Bumbu stated that they would vaccinate against covid-19. Perceptions of barriers, benefits, vulnerabilities, severity, and triggers to move have an influence on acceptance of the covid-19 vaccination.
T Pengaruh Efek Samping Obat Terhadap Kepatuhan Penggunaan Obat Pada Pasien Penyakit Jantung Koroner Di Rsud Brigjend H.Hasan Basry Hulu Sungai Selatan: Pengaruh Efek Samping Obat Terhadap Kepatuhan Penggunaan Obat Pada Pasien Penyakit Jantung Koroner Di RSUD Brigjend H.Hasan Basry Hulu Sungai Selatan Nur Lathifah; Iwan Yuwindry; Muhammad Zulfadhilah
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.216

Abstract

Background: Coronary heart disease (CHD) is a condition caused by blockages in the arteries of the heart. CHD is the most common cause of cardiovascular disease worldwide, 45% of 9.4 million deaths are caused by CHD. CHD cases in Indonesia reached 1.2 million cases and increased to 2.7 million people who experienced CHD. The presence of CHD drug side effects and discontinuation of drug therapy is one of the risk factors for treatment failure Objective: Analyzing the effect of drug side effects on adherence to drug use in CHD patients at Brigjend H. Hasan Basry Hospital Hulu Sungai Selatan. Methods: This type of quantitative research uses an analytical observational design with a Cross Sectional design and the type of Purposive Consecutive Sampling. The sampling period was 4 weeks with a sample of 50 respondents with CHD. Data analysis used univariate and bivariate analysis with Spearman Rho test. The research instrument used the Naranjo questionnaire for drug side effects and MMAS-8 for adherence. Results: The results of this study indicate that there is a correlation between the variables of CHD drug side effects and drug use compliance which shows an effect with a significance value of 0.001 and a correlation coefficient of 0.470 which has a positive correlation direction with moderate strength of the relationship. Conclusion: there is a significant effect between the effects of side effects of CHD drugs on adherence to drug use in CHD patients at Brigjend H. Hasan Basry Hospital Hulu Sungai Selatan.
R Penurunan Kadar Logam Timbal (Pb) Pada Daging Ikan Kelabau (Osteochilus melanopleurus) Dengan Filtrat Asam Jawa (Tamarindus indica): Penurunan Kadar Logam Timbal (Pb) Pada Daging Ikan Kelabau (Osteochilus melanopleurus) Dengan Filtrat Asam Jawa (Tamarindus indica) Felix Imanuel Rachman; Rahmadani Rahmadani; Muhammad Rizal
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.217

Abstract

Background: Tamarind has citric acid which has the ability to reduce heavy metal contamination. Citric acid with its tricarboxylic group can bind with heavy metals and produce complex ions and has stable properties in the form of chelates. Objective: To analyze the correlation between public knowledge and the use of drugs for toothache in the working area of the Asam- Asam Public Health Center. Methods: Seeing the effect of tamarind on lead heavy metal and the relationship between variations in tamarind concentration and decreased levels of lead heavy metal in fish meat. Methods: This study used a pre-experimental method with only-posttest design approach using atomic absorption spectrophotometry (AAS) instruments. Results: Based on the research that has been done, it was found that the decrease in metal content from treatment with tamarind 5% was 63.923%, tamarind 10% was 41.431%, and tamarind 10% was 26.484% with a significance result of 0.715. Conclusion: Based on the results of the study, it was found that there was no relationship between variations in the concentration of tamarind and lead levels.
B BARRIER DAN SELF-EFFICACY APOTEKER DALAM PROMOSI KESEHATAN DI FASILITAS KESEHATAN TINGKAT PERTAMA KOTA BANJARBARU: BARRIER DAN SELF-EFFICACY APOTEKER DALAM PROMOSI KESEHATAN DI FASILITAS KESEHATAN TINGKAT PERTAMA KOTA BANJARBARU Nurul Mardiati; Elsa Munajad; Rahmi Hidayati
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.218

Abstract

Introduction: Health promotion is more focused on maintaining and increasing the degree of well-being rather than returning health due to illness or accidents. The barrier is an obstacle or obstacle experienced by the pharmacist in carrying out health promotion, while self-efficacy, also known as self-confidence, is a good attitude that a person has when they are confident in their ability to form positive judgments about both themselves and their environment. Objective: The purpose of this study is to characterize the barriers to health promotion, as well as self-efficacy in doing so, and the relationship between the two. Methods: Using a cross-sectional design, this study's respondents were. After distributing questionnaires to 20 pharmacists, a purposive sample method was used to choose the participants. Results: In the Banjarbaru City FKTP, the majority of pharmacists—13 individuals, or 65%—have a high barrier to health promotion. Lack of time (70%) and the absence of uniform standards for pharmacists (65%) are major obstacles. The majority of pharmacists, or 12 individuals, also exhibit strong self-efficacy. When pharmacists who work at the Banjarbaru City FKTP promote health, there is a correlation between obstacles and self-efficacy. Conclusion: In order to undertake health promotion, there is a relationship between the barrier and self-efficacy.
A Analisis Cemaran Bakteri Coliform Dan Identifikasi Bakteri Escherichia Coli Pada Air Galon Di Desa Sungai Danau: Analisis Cemaran Bakteri Coliform Dan Identifikasi Bakteri Escherichia Coli Pada Air Galon Di Desa Sungai Danau Taufik Kurahman; Rohama Rohama; Rina Saputri
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.224

Abstract

Currently, the use of refill drinking water depots (DAMIU) is relatively higher, so that the use of DAMIU must pay attention to sanitation and hygiene to support DAMIU to avoid contamination with Coliform bacteria, one example of Coliform bacteria is Escherichia Coli bacteria. Escherichia coli bacteria is one of the causes of diarrheal disease. Diarrhea is an endemic disease with the potential for extraordinary events (KLB) which often leads to death in Indonesia. The prevalence of diarrhea in Indonesia is 6.8% or 1,017,290 people and it is known that Tanah Bumbu district is the third largest contributor to diarrhea, which is 4.3% or as many as 2006 people in South Kalimantan, so it is necessary to test DAMIU in Sungai Danau Village. using the MPN method.
H Hubungan NF-kB Pada Diabetes Dislipidemia : Literature Review: Hubungan NF-kB Pada Diabetes Dislipidemia : Literature Review Nungky Yulia; Saftia Aryzki; Muhamma Rizki Ikhsan
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.233

Abstract

Background: The NF-kB cytokine that produced can induces an acute phase called low-grade inflammation which is part of the activity of the innate immune system. this is associated with the pathogenesis of type 2 DM, then complications occur, namely dyslipidemia and atherosclerosis. Proinflammatory cytokines that act as stress inducers in endoplasm which can increase insulin metabolism and in type 2 diabetes, which is characterized by decreased insulin production and insulin resistance.Objective: This study aimed to identified and analyzed the relationship of NF-kB with diabetic dyslipidemia.Methods: Assessment of criteria in this literature review study using The JBI Critical Appraisal Tools to assessed the risk of bias in the study with type of study was Randomized Controlled Trials. this study conducted by using data on article from data base such as PubMed, Elsevier, google schoolar, etc.Results: NF-kB had Relationship with diabetic dyslipidemia with the results of P value> 0.005 and significance value of serum TNF-a level (p = 0.002), serum IL-6 level (p = 0.067) in diabetes induced dyslipidemia. Diabetic dyslipidemia that analyzed with insertion genotype showed increased in proinflammatory cytokine expression and activity of NF-kB.Conclusion: Most research results stated that there was a relationship between NF-kB with diabetic dyslipidemia. This was proven with high serum and TNF-a levels NF-kb, that played a role in complications related to diabetes mellitus through its role in inducing inflammation.
Pengaruh Pengaruh Perbedaan Jenis Pelarut Terhadap Kadar Fenolik Ekstrak Daun Sirsak (Annona Muricata L.): Pengaruh Perbedaan Jenis Pelarut Terhadap Kadar Fenolik Ekstrak Daun Sirsak (Annona Muricata L.) Maria Dwi Ayu Listiawati; Kunti Nastiti; Mia Audina
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.234

Abstract

Backgraund: Annona muricata L leaves are used as anticancer drugs by the public because Annona muricata L leaves have a high content of phenolic compounds that have antoxid activity that can ward off free radicals that cause cancer. Phenolic compounds have polar properties so that to obtain this compound the same polar solvents are used, namely ethanol 70%, ethanol 96% and Methanol where the use of different types of solvents will affect the resulting phenolic level. Objective: Knowing what are the levels and influences of differences in phenolic levels of leaves Annona Muricata L. leaves based on differences in solvent types Methods: This study used a pre-experimental method with a randomized design by conducting a maceration extraction method and then a Thin Layer Chromatography test was carried out to identify phenolic compounds. Then the determination of total phenolic levels using UV-Vis spectrophotometry. Results: Effect of differences in solvent type from phenolic levels with One Way ANOVA parametric test. The total phenolic content of Annona muricata L leaves of Ethanol extract was 70%, Ethanol 96% and Methanol obtained were 5,753 mg GAE/g, 4,022 mg GAE/g and 7,179 mg GAE/g. Differences in solvent type had a significant effect of 0,000 (p<0,05) on the phenolic levels of Annona Muricata L leaf extract. Conclusions: Based on the results of the study, it was concluded that methanol is effective in irradiating phenolics compared to other types of solvents.
P Perbandingan Kadar Flavonoid Total Berdasarkan Perbedaan Konsentrasi Pelarut Etanol Dari Ekstrak Daun Pegagan (Centella asiatica [L] Urban): Perbandingan Kadar Flavonoid Total Berdasarkan Perbedaan Konsentrasi Pelarut Etanol Dari Ekstrak Daun Pegagan (Centella asiatica [L] Urban) Syifa Khairunnisa; Ali Rakhman Hakim; Mia Audina
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 1 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i1.236

Abstract

Background: Centella asiatica [L] Urban leaves are empirically used for the treatment of acne. One of the chemical compounds that have pharmacological effects is flavonoids. Polar flavonoid compounds can be drawn using polar solvents based on different polarity levels, which can affect the total flavonoid content obtained. Objective: To determine the effective and optimal concentration of ethanol solvent to obtain total flavonoid content from the leaf extract of gotu kola (Centella asiatica [L.] Urban). Methods: This study used a pre-experimental method with a randomized block design and the research method was maceration extraction, qualitative test of color reagents and thin layer chromatography and determination of total flavonoid content using UV-Vis Spectrophotometry. Data analysis to determine the effect of differences in the concentration of ethanol solvent using the non-parametric Mann-Whitney test. Results: The results of the qualitative test of color reagents and thin layer chromatography were positive for flavonoids. Determination of total flavonoid content of 70% ethanol extract was 4,339 mg QE /g and 96% ethanol extract was 1,895 mg QE /g. The results of data analysis of ethanol solvent concentration had a significant effect on total flavonoid levels. Conclusion: Based on the results of research, 70% and 96% positive ethanol extract contains flavonoid secondary metabolite compounds from the results of measuring the total flavonoid levels of ethanol extract 70% more effective in irradiating flavonoids and ethanol solvent concentrations affect total flavonoid levels.

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