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Jurnal Ilmu Kesehatan Indonesia (JIKSI)

jikesi
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Published by Universitas Andalas

ISSN : - EISSN : 27224848 DOI : https://doi.org/10.25077/jikesi.v1i3

Core Subject : Health, Science,

Immunology & microbiology Medicine & Pharmacology Public Health

Jurnal Ilmu Kesehatan Indonesia is a peer-reviewed and open-access journal that focuses on promoting health sciences to integrate research in all aspects of human health. This journal publishes original articles, reviews, and case reports. Subjects suitable for publication include but are not limited to the following fields: Anesthesiology Cardiovascular Cell and molecular biology Child health Dermato-venereology Histopathology Internal medicine Neuro-psychiatric medicine Nutrition Obstetrics and Gynecology Ophthalmology Otorhinolaryngology Pharmacology Pulmonology Radiology Surgery

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 306 Documents

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Gambaran Histopatologi Hepar Mencit (Mus musculus Balb/C) yang Diinfeksi dengan Plasmodium berghei Hanifah Putri Dwiridal; Adrial Adrial; Eryati Darwin
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 2 (2021): Juni 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background: The most common cause of death by malaria in Indonesia is Plasmodium falciparum, which is analogous to Plasmodium berghei, which lives as a parasite in the liver of mice. The damage caused is seen in severe hepatocyte cell damage, which can be prevented by immunization, but the right type of immunization has not been found. Objective: This study aims to see whether immunization with Anopheles sundaicus salivary gland extract in mice can reduce liver damage in mice that have been infected with Plasmodium berghei. Methods: This research was conducted at the Anatomical Pathology Laboratory, Faculty of Medicine, Andalas University, from May - September 2020. The research method was descriptive with a quantitative approach. View and compare the histopathological picture of the liver of mice, which were infected with Plasmodium berghei after being immunized with Anopheles sundaicus salivary gland extract, in the pellet extract and supernatant extract groups, and the control group who were not immunized. The preparations were viewed using a microscope (Binocular Olympus BX 51 DIC), the number of hepatocytes was counted using the Image J application and the percentage of damage was calculated using the formula by Baldatina (2008). Results: The percentage of hepatocyte cell damage in the mencit control group was 96.27%, pellet extract 88.88% and supernatan extract 85.93%. Conclusion: The highest percentage of hepatocyte cell damage was found in the mencit control group and the lowest damage percentage in the supernatan extract group.

Profil Penderita Anemia Aplastik di RSUP Dr. M. Djamil Padang Tahun 2018-2019 Amanda Rizki; Zelly Dia Rofinda; Gusti Revilla
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background. Aplastic anemia is a failure of the process of formation and development of blood cells that causes a decrease or absence of hematopoietic precursor cells in the bone marrow. Although the prevalence of this disease is rare, aplastic anemia has the potential to cause death with risk factors that are easily found in everyday life and are rarely realized.Objective. To determine the profile of patients with aplastic anemia at General Hospital Dr M Djamil Padang.Methods. This is a descriptive retrospective study. The population of this study are all patients diagnosed with aplastic anemia by clinicians in the Medical Record Installation of Dr. M. Djamil Hospital, Padang, between 1 January 2018 - 31 December 2019..Results The results showed that 21.57% patients with aplastic anemia were at the age of 56-65 years and the incidence was higher in women than men. The highest risk factor was exposure to chemical and insecticides (18.62%), but 54.9% of the data did not include risk factors. 31.37% work as students. 67.65% suffered from mild aplastic anemia, 60.78% were on immunosuppressive therapy, and 65.69% had partial remission outcomes.Conclusion. The majority of patients with aplastic anemia based on age are 56-65 years and based on gender, the incidence is higher in women. The most common risk factors were exposure to chemical and insecticides. . The most common level of severity is non-severe aplastic anemia. The most common type of therapy is immunosuppressive therapy. The most common outcome is partial remission.

Gambaran Korban Meninggal Dunia dengan Cedera Kepala pada Kecelakaan Lalu Lintas di Bagian Forensik RSUP dr M Djamil Padang Tahun 2018-2019 Muhammad Imam Arrasyid; Rika Susanti; Roza Mulyana
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background. A traffic accident is an incident on the road which accidentally involves a vehicle with or without other road users which results in human casualties and/or property loss. The most common injury that occurs during traffic accidents is head injury. Head injury due to traffic accidents is a major cause of disability and mortality in developing countries.Objective. To analyze the overview of victim who died with head injury in traffic accidents at the forensic department of DR. M. Djamil Padang 2018-2019.Methods. This type of research is retrospective descriptive. Sampling was carried out by total sampling technique in the forensic department of RSUP Dr. M. Djamil Padang from March 2020 - September 2020.Results. The results showed that 150 victims who died with head injury in traffic accidents. The conclusion of this study, most of the age is 15-29 years and the incidence was higher in males. The most common injury patterns are abrasions.The head region most affected is the frontalis region. The most time for accidents is at 12.01-18.00 WIB and the most accident days are on Sundays. Most of the accident locations were outside the city of Padang, most types of vehicles were motorbikes, the role of the most victims were motorists and the most types of accidents were being hit by other vehicles.Conclusion. Most of the age is 15-29 years and the incidence was higher in males. The head region most affected is the frontalis region. Most of the accident locations were outside the city of Padang, most types of vehicles were motorbikes, the role of the most victims were motorists and the most types of accidents were being hit by other vehicles

Gambaran Pemeriksaan Ultrasonografi pada Pasien Struma di Bagian/SMF Radiologi RSUP DR. M. Djamil Periode Januari–Desember 2019 Irfan Fadilah; Dina Arfiani Rusjdi; Dinda Aprilia
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background: A goiter is an enlargement of the thyroid gland caused by abnormalities of the thyroid gland in the form of malfunctioning or disorders of the structure of the gland and its morphology. According to WHO, the incidence of goiter is still quite high with iodine deficiency as the main cause. Objective: This study aims to determine the description of ultrasound examinations in goiter patients in Department of Radiology DR. M. Djamil January-December 2019 period. Method: This research was a retrospective descriptive study using cross sectional method using secondary data on 123 patients with thyroid goiter who meet the inclusion criteria in RSUP DR. M. Djamil Padang period January 2019-December 2019. The sampling method used a total sampling technique. Result: The results showed that 112 patients with thyroid goiter disorders met the inclusion criteria. The most clinical diagnosis results were goiter nodusa as many as 61 people (54.5%). The highest incidence was in the age range 41-50 years with 35 people (31.3%). The most gender was 88 women (78.6%). The results of ultrasonography in most goiter patients were diffuse in 43 people (38%).Conclusion: The conclusion of this study, it was found that the most age group of patients suffering from goitre were 41-50 years old, the majority of goiters occurred in the female compared to the male and the results of the most thyroid ultrasound images were diffuse goiter

Pengaruh Ramipril Terhadap Gambaran Histopatologis Otak Tikus Wistar yang Mengalami Edema Otak Rizka Fitria Husni; Nita Afriani; Aswiyanti Asri
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background. Brain edema is excessive accumulation of fluid in the intracranial or extracellular space of the brain. It can be caused by head trauma, brain tumors, hypoxia, metabolic disorders, or acute hypertension. Acute myocardial infraction is damage to the myocard that occurs due to lack oxygen. When acute myocardial infarction occurs, there will be disruption of blood flow in the form of stasis which allows emboli and decreased Cardiac Output which will cause a decrease in Cerebral Blood Flow. There will be a state of ischemia and hypoxia so that the hemostatic mechanism is disturbed which will trigger brain edema. Objective. This research was conducted to see the effect of giving ramipril to histopathological of the brain of wistar rat with brain edema. Methods. This research is an experimental study. We used 32 animals which were divided into 4 groups (K-, K +, P1, and P2). P1 was given 3 mg/kgBW ramipril for 7 consecutive days. P2 was given 4 mg/kgBW ramipril for 7 consecutive days. On days 8 and 9, P1, P2, and K+ induced isoproterenol 85 mg/kgBW for 2 consecutive days to induce brain edema through the mechanism of acute myocardial infarction. Data analysis was performed using One Way Anova test and Post Hoc Bonferroni test. Results. The mean area of brain edema in the K-, K +, P1, and P2 groups respectively were 20.76%, 34.69%, 22.70%, and 21.90%. Conclusion. There was a significant effect of giving ramipril to histopathological of the brain of wistar rat with brain edema

Hubungan Miopia dengan Skor IQ (Intelligence Quotient) pada Siswa SMP Negerti 1 Kota Padang Jonas Hansel Tarigan; Muhammad Syauqie; Bobby Indra Utama
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background. Myopia is one of the most common refractive errors. Refractive disorders indicate a relationship with IQ (Intelligence Quotient). It was first found to show that the higher the person's myopia the higher the IQ score he obtained.Objective. This study aims to determine the relationship between myopia and IQ scores in students of SMPN 1 Padang City.Method. This research is a comparative analytical study with a cross-sectional design using primary data and secondary data from May 2020 - August 2020 at SMPN 1 Padang. The sample consisted of 44 people with 22 people as cases and 22 people as controls. Data analysis used univariate analysis and bivariate analysis. The r value indicates the strength of the correlation and the results are statistically significant if the p value is <0.05.Result. The results showed that most of the respondents consisted of female students (52.3%), the incidence of myopia was found more in female students (72.7%), the highest degree of myopia was obtained by mild myopia (59.1%), the highest IQ score was obtained. with a high level of intelligence (65.9%) with a mean; myopia IQ score 117 ± 17.5, control IQ score 121.68 ± 16.3. In several bivariate analyzes, it was found that there was no relationship between myopia and IQ score (p> 0.05).Conclusion. In this study, there was no significant relationship between myopia and IQ score.

Hubungan Jumlah Eosinofil dengan Ukuran Polip Nasal dan Karakteristik Pasien yang Didiagnosis di Sentra Diagnostik PA FK-UNAND Tahun 2017-2019 Salma Yuri Khairunnisa; Tofrizal Tofrizal; Netti Suharti
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background: Nasal polyps is a soft masses filled with fluid in nasal mucosa. The incidence is not high, but nasal polyps are related with inflammatory process. Factors that can affect nasal polyps are eosinophils, polyp size, age and gender of the patient. Objective: This study aims to discuss the association between eosinophils with polyp size, age and gender of polyp patient. Methods: The type of this study was an analytic using a cross sectional approach. This research took place from February- October 2020 in the Pathology Anatomy Diagnostic Central of Faculty of Medicine, Andalas University with 19 total sample and this study used total sampling technique. Results: The results based on bivariate analysis of Chi-Square test between amount of eosinophils with polyp size, age and gender of polyps patients have p values (p = 0, 036), (p = 0.264), (p = 1, 00). Conclusion: There is a significant relationship between eosinophils and polyp size. There is no significant relationship between eosinophils with age and gender of patients with nasal polyps in the Pathology Anatomy Diagnostic Central of Faculty of Medicine, Andalas University in 2017- 2019.

Pemeriksaan Bercak Darah pada Kain yang Direndam & Dikubur Menggunakan Tes Teichmann Puji Anugrah; Citra Manela; Syamel Muhammad
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background. Blood is the most important physical evidences and often found at crime scene. The Teichmann test is a confirmation test to check whether the spot really a blood.Objective. This study aims to identify the bloodstain on cloth soaked in water and buried in the ground using Teichmann test.Method. The research type is a descriptive study with a laboratory experimental study design. The sample of this study was a cloth dripped with blood, 27 samples are immersed in a bucket filled with water and 27 other samples are buried in the ground with a depth of 20 cm. The examination using the Teichmann test will be carried out on the 6th to the 14th day of exposure.Result. From the research that has been done, the results of the Teichmann test were positive on blood spots on cloth soaked in water and buried in the ground on the 6th to 9th day of exposure. Positive results indicate the formation of hemin hydrochloride crystals in the form of blackish-brown rods.Conclusion. The conclusion of this study is hemin hydrochloride crystals can still be found in blood stains on cloth soaked in water and buried in the soil using the Teichmann test but limited to the 9th day of exposure.

Hubungan Usia, Hemoglobin, dan Indeks Massa Tubuh dengan Perubahan Ukuran Tumor pada Kemoterapi Neoadjuvant Kanker Serviks Stadium IB2 dan IIA2 di RSUP Dr. M. Djamil Padang Nisa Ayu Farma; Syamel Muhammad; Asterina Asterina
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background. On stage IB2 and IIA2 of cervical cancer standard treatment such as neoadjuvant chemotherapy is required. The changes in tumor size of this therapy is influenced by several factors, among others are Age, Hb, and BMI.Objective. To determine the relationship of Age, Hb, and BMI with changes in tumor size to neoadjuvant chemotherapy of servical cancerMethods. This of research was analytical research with using a cohort retrospective design with a total sample of 35 patients. The research instrument used was a medical record then analyzed with a with a dependent sample t-test and simple regression linier correlation test.Results. The result obtained a moderate negative power relationship between age and changes in tumor size (R= -0,412 ; P= 0,014), and there was no significant relationship between changes in tumor size with hemoglobin rate ( R= -0,107 ; P= 0,541), and BMI ( R= -0,117 ; P= 0,545).Conclusion. There is a significant relationship between age and changes in tumor size, and there is no significant relationship between hemoglobin and body mass index with changes in tumor size.

Gambaran Histopatologi Ginjal Mencit (Mus musculus Balb/C) yang Diinfeksi dengan Plasmodium berghei Miftah Ar Rahmah; Adrial Adrial; Yenita Yenita
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background: P. berghei is a parasite that causes malaria in small rodents. This parasite is analogous to P. falciparum which causes severe malaria in humans with the highest risk of death compared to 4 other plasmodium species. Complications of falciparum malaria in renal microcirculation is AKI (Acute Kidney Injury). AKI is preceded by the incidence of ATN (Acute Tubular Necrosis) and MPGN (Mesangioproliferative Glomerulonephritis) with ATN being the highest prevalence. Objective: This study aims to determine the histopathological appearance of renal tubules of white mice Mus musculus Balb/C which are infected with P. berghei. Methods: Descriptive analysis method with quantitative approach is used in this study. The study was conducted at the Anatomical Pathology Laboratory of the Faculty of Medicine, Andalas University. The study was conducted since February to October 2020. The sample size was determined by the Federer formula (2008). Results: Percentage of renal tubular cell damage which were 8.42% for the control group, 4.52% for the pellet extract group, and 2.74% for supernatant extract group. Conclusion: The study concluded that highest percentage of kidney tubular cell damage was found in the kidney of mice immunization with the control group, and the lowest percentage of kidney tubular cell damage was found in the kidney of mice immunization with supernatant extract.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Fathiyyatul Khaira

Contact Email fathiyyatul.khaira@gmail.com

Phone +6285161910033

Journal Mail Official jikesi.editorial@gmail.com

Editorial Address Fakultas Kedokteran Universitas Andalas. Jln. Limau Manis, Pauh – Padang – Sumatera Barat. 25163.

Location Kota padang, Sumatera barat INDONESIA

Abstract

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Contact Name
Fathiyyatul Khaira

Contact Email
fathiyyatul.khaira@gmail.com

Phone
+6285161910033

Journal Mail Official
jikesi.editorial@gmail.com

Editorial Address
Fakultas Kedokteran Universitas Andalas. Jln. Limau Manis, Pauh – Padang – Sumatera Barat. 25163.

Location
Kota padang,

Sumatera barat

INDONESIA