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Zahratul Aini
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JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Published by Universitas Islam Indonesia
ISSN : 20854145     EISSN : 25272950     DOI : 10.208885/JKKI.Vol10.Iss3.art5
Core Subject : Health,
Medicine & Pharmacology Public Health
JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and case report. These comprise of biomedical sciences, clinical medicine, public health sciences, and medical science education.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 468 Documents
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The correlation between skin type and acne scar severity in young adults Yessica Mishellin Awaloei; Nawanto Agung Prastowo; Regina Regina
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 1, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss1.art9

Abstract

Background: Acne is the most common skin disorder, especially in adolescents and youths. Inflammation due to acne may leave scar tissue. The scar severity may correlate with gender and skin type. Objective: This study aims to investigate the correlation between gender, skin type, and acne scar severity in youth. Methods: This is a cross-sectional study with 132 (81 female) medical college students aged from 18 to 23 participated in the study. Skin type was assessed using a Baumann Skin Type questionnaire. Acne scar severity was evaluated using the Qualitative Global Scarring Grading. Skin examination was conducted through the image from the face photograph. Lambda test was used to confirm the correlation between gender, skin type, and acne scar severity. Multiple logistic regression was applied to determine the odd risk of gender and skin type to moderate-severe acne scar. Significance was set at p<0.05.Results: Most of the participants (80.3%) had oily skin, and 22 participants (16.7%) had moderate-severe acne scar. A weak positive correlation was confirmed between skin type and acne scar severity (p<0.01, r=0.3). Oily skin type has 4.3 times greater risk of developing more severe acne scar (p<0.01, 95%CI = 1.90-9.90).Conclusion: Skin type is correlated with acne scar severity. Oily skin type is at greater risk of developing severe acne scar.
The decrease of histomorphometry and function of pancreas in male albino rats after induced by sleep deprivation Fitranto Arjadi; Nur Signa Aini Gumilas; Ika Murti Harini; Pugud Samodro; Andromeda Andromeda
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 2, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss2.art3

Abstract

Background: Sleep disturbance accelerates type 2 diabetes mellitus by reducing insulin secretion and by the occurrence of difficulty in controlling sleep behaviour in humans so that it is necessary conduct a study by using experimental animals.Objective: This study aims to determine histophotometric differences of pancreas and differences of glucose tolerance in male albino rats (Rattus norvegicus) after induced by stress paradoxical sleep deprivation (PSD) and total sleep deprivation (TSD). Methods: This study applied a post-test only with control groups consisting of 30 male albino rats (Wistar strain) divided randomly into 3 groups: control group, PSD group and TSD group. The mean number and diameter of islets of Langerhans were calculated per slide and were averaged for each group at a magnification of 400 X. The percentage of beta cells in one islet of Langerhans was (ß-p) that was a number of normal beta cells (Bn) divided for the total beta cells (Bt) (normal and damaged) x 100%. The glucose level based on the sampling time was made a curve shape, and the area under the 0-to-120-minute curves (AUC0-120) was calculated by using a trapezoidal formula.Results: The lowest AUC0-120 level of glucose was the control group (14,082 ± 955mg/dL) and the highest was the TSD group (16,293 ± 2,195 mg/dL); the Post-Hoc LSD test showed a significant difference (p<0.05) between the control-PSD group and the TSD-control group. The mean result of pancreatic ß cells mass with the lowest number was in the TSD group (76.3 ± 4.8), and the highest result was in the control group (94.3 ± 2.7); Post-Hoc LSD showed a significant difference (p <0.05) in the control-PSD group and the TSD-control group. The lowest mean in cell diameter of islets of Langerhans was in the TSD group (0.132 ± 0.031 mm), and the highest mean was in the control group (0.213 ± 0.019 mm). Conclusion: Sleep deprivation could reduce pancreatic ß cell mass and cell diameter of islets of Langerhans and increase glucose tolerance levels.
Therapeutic Plasma Exchange (TPE) as an effective supportive therapy for COVID-19 case with Acute Respiratory Distress Syndrome (ARDS) and thrombophilia: A Case Report Reviono Reviono; Arifin Arifin
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 1, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss1.art13

Abstract

Coronavirus Disease (COVID-19) has rapidly spread and caused a high number of mortalities. To this day, effective therapy to cure this virus is yet to be found. A number of treatments were tested; however, the result is not satisfactory. Therapeutic plasma exchange (TPE) is one of the supportive therapies applied to treat COVID-19 patients with moderate to severe symptoms. We reported 41 years old male patient diagnosed with severe COVID-19 infection, acute respiratory distress syndrome (ARDS), and thrombophilia. The patient received a therapy following the Ministry of Health’s guideline for COVID-19 handling. On the third day, respiratory failure occurred with a P/F ratio of 255 and the chest X-ray result showed vascular streak and ground-glass opacity; thus, the hospital decided to perform TPE. The TPE was performed twice in 5 days interval. After TPE was administered, clinical development is observed both subjectively in the form of reduced symptoms, normal respiration rate, and objectively, the improvement in blood gas analysis, increased O2 saturation, and a decrease in interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-a) level significant clinical laboratory and radiological improvement possibly due to cytokine storm which is remedied by TPE action.
Slow deep breathing: Adjuvant physiological intervention to deal with COVID-19 Om Lata Bhagat
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 3, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss3.art1

Abstract

No abstract
Challenges of malaria elimination in Indonesia Novyan Lusiyana
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 3, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss3.art2

Abstract

No abstract
Prevention of noise induced hearing loss in worker: A literature review Febri Endra Budi Setyawan
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 2, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss2.art12

Abstract

Noise induced hearing loss (NIHL) is a hearing loss due to noise that exceeds the hearing threshold limit value (TLV) in a work environment. Impacts of this disorder are decreased concentration, fatigue, headaches, sleep disturbances, and loss of job. Therefore, it is very important for industry stakeholders and workers to understand about the NIHL, so they can prevent and rehabilitate  this problem. Risk factors that affect degrees of severity of deafness are noise intensity, frequency, duration of exposure per day, length of work, individual sensitivity, age and other factors that can cause deafness. Based on this, it can be understood that an amount of received exposure of noise energy will be similarly proportional as obtained damage. In general, NIHL cannot be cured but can be prevented and rehabilitated. Its prevention can be by applying hearing conservation program (HCP) such as noise measurement procedure, noise control, periodic audiometry measurement, hearing protection, worker education, recording, and evaluation. Some of benefits that can be obtained from the hearing conservation program are as a guide to diagnose hearing loss to prevent health impacts from noise exposure.
Effect of antiretroviral therapy to liver function of people living with HIV/AIDS patients in West Papua Mirna Widiyanti; Setyo Adiningsih; Evi Iriani Natalia; Dedi Ananta Purba
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 2, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss2.art4

Abstract

Background : Antiretroviral (ARV) therapy is one of the efforts to combat HIV/AIDS in Indonesia, especially West Papua. One of the side effects using ARV is impaired liver function in People Living with HIV/AIDS (PLWHA). ARV therapy evaluation to liver disorders can be seen from the Serum Glutamic Oxaloacetic Transaminase (SGOT)/ Serum Glutamic Pyruvic Transaminase (SGPT) level.Objective : To find out the effect of ARV Fixed Dosed Combination (FDC) to liver function of PLWHA patients in West Papua.Methods : A cross-sectional study, involving 110 respondents who were PLWHA patients receiving ARV at Voluntary Counselling and Testing (VCT) service of hospital in Manokwari, Sorong, and Fak-fak. Laboratory tests was used to examine the liver function. Other variable data were obtained from medical records. The Fisher Exact Test with a significance level of <0.05 was used to determine the effect of ARV to liver function.Results : Respondents had no liver problems with normal SGOT and SGPT values, i.e. 72,7% and 76.4%, respectively. While, the rest had mild and moderate toxicity. Respondent experiencing moderate toxicity was 2 patients who regularly took FDC in Sorong.Conclussion : The FDC using in ARV therapy did not significantly influence the increase of SGOT and SGPT on PLWHA patients in West Papua.
Phenomena of bullying behaviour on adolescents in boarding school Ema Waliyanti; Fauziah Anggitha Swesty
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 2, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss2.art5

Abstract

Background: A large number of bullying cases occurred on adolescents in boarding schools can impact on physical and psychological conditions that make them inconvenient in their schools and boarding schools. Boarding schools are more prone of bullying incidents than public schools because their students interact each other more often, either in their schools or dorms. Objective: This study aims to observe bullying behaviour of adolescents in a boarding school in Yogyakarta.Methods: This study was a qualitative method with a phenomenological approach. Its data collection technique was conducted by interviewing. There were 11 participants in this study consisting of eight adolescents and three boarding school teachers who were determined by a purposive sampling. To validating its data, this study used a source triangulation, peer debriefing, and thick description. Then, its data analysis applied the Open Code 4.03. Results: This study showed that bullying behaviour occurred in the boarding school were physical bullying, verbal bullying and relational bullying. Factors that contributed for the bullying behaviour were physical forms, social intercourses of adolescent, emotional attitudes, histories of bullying, seniority, and bullying punishment that are applied ineffectively. Responding to the bullying incidents, the boarding school made policies by making rules about bullying, intervening by advice, applying school punishment, and initiating preventative effortsConclusion: Bullying behaviour of the adolescent occurred in the boarding school includes physical bullying, verbal bullying, and relational bullying that requires attention from all parties, including schools. Schools are expected to provide socialization related to the bullying and to cooperate with all school members to prevent repetitive incidents of bullying.
The potency of red onion skin flavonoids in acetaminophen-induced liver injury management: A biomolecular review Radya Kusuma Ardianto; Lucky Dimas Abimanyu; Afif Wafiq Waliyuddin; Abi Noerwahjono; Dian Yuliartha Lestari; Fathiyah Safithri
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art12

Abstract

Acetaminophen is widely used as a fever and pain reliever drug. However, acetaminophen intoxication was common and responsible for thousands of acetaminophen-induced liver injury (AILI) cases worldwide. It was understood that glutathione (GSH) depletion causes a deposit of acetaminophen metabolites which are toxic to liver cells. N-acetylcysteine (NAC), used as acetaminophen intoxication therapy, has been reported to cause side effects such as nausea, vomiting, and anaphylactic reaction. This narrative review aimed to discuss other potential candidates in AILI management. The biomolecular approach was used to investigate onion skin in-depth and holistic discussion. According to the results, onion peel extract is rich in flavonoids (quercetin and kaempferol) and potentially be a candidate in the management of AILI through proposed mechanisms such as restoration of reduced glutathione (GSH), inhibition of cytochrome P450 (CYP) enzymes, upregulation of uridine 5'-diphospho-glucuronosyltransferase (UGT) enzyme, and inhibition of TLR4 activity. 
Outcome benefits to transurethral resection of the prostate in patients with benign prostatic hyperplasia at Medan regional hospital Richman Patandung; Syah Mirsya Warli
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 2, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss2.art6

Abstract

Background: Benign prostatic hyperplasia (BPH) is a pathologic process that cause of lower urinary tract symptoms (LUTS) in aging men. Transurethral resection of the prostate (TURP) is still the current gold standard of BPH treatment. International Prostate Symptoms Score (IPSS) and the quality of life (QoL) index are used for assessing the TURP results.Objective: This study would like to show the benefits outcome of TURP in patients with BPH evaluated with IPSS score and QoL index in Medan regional hospital.Methods: This research is a retrospective study of BPH patients that is treated with TURP at Universitas Sumatera Utara Hospital from September 2019 – August 2020. Patients will be divided into 2 groups, group 1 with patients who have a prostate size <80 grams and the second group with a prostate size> 80 grams. All patients who were included in this study were assessed for their complaints using the IPSS and QoL index before and after taking an operation. Statistical analysis was performed using independent t test and Mann Whitney test. The data were significant if the p value < 0.05. Results: There are 60 patients enrolled in this study that treated with TURP. The mean age of patients in the group 1 was 69.57 ± 7.698 years and 69.84 ± 5.893 years in the group 2. There is no significant difference between group 1 and group 2 in postoperative IPSS and QoL results (p >0.05). Conclusion: TURP procedure is preferable option of BPH for patients in any prostate size.

Page 28 of 47 | Total Record : 468

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