cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Editor PSR
Contact Email
article@farmasi.ui.ac.id
Phone
+62-21-27608403
Journal Mail Official
psr@farmasi.ui.ac.id
Editorial Address
3rd Floor, A Building, Rumpun Ilmu Kesehatan Kampus Baru UI Depok, 16424, Indonesia
Location
Kota depok,
Jawa barat
INDONESIA
Pharmaceutical Sciences and Research (PSR)
Published by Universitas Indonesia
ISSN : 24072354     EISSN : 24770612     DOI : https://doi.org/10.7454/psr
Core Subject :
Aims Pharmaceutical Sciences and Research (PSR), an international, peer-reviewed, open access, and official journal from Faculty of Pharmacy, Universitas Indonesia, aims to disseminate research results and findings in Pharmaceutical Sciences and Practices. Major area of interest is natural products in drug discovery and development. We also consider other areas related to pharmaceutical sciences and practices. PSR publishes content in English language to promote the sharing of knowledge to international scholars. PSR publish 5 types of articles: 1. Original article 2. Case report 3. Case series 4. Review article 5. Mini review article Scope Researches in Pharmaceutical Sciences and Practices which are covered by PSR are within these subject areas: - Pharmacognosy and Phytochemistry - Pharmaceutical Chemistry - Pharmaceutical Technology - Pharmaceutical Biotechnology - Clinical Pharmacy - Pharmacology-Toxicology - Social and Administrative Pharmacy, including Pharmacoeconomy
Arjuna Subject : -
Articles 9 Documents
 1 
Search results for , issue "Vol. 4, No. 1" : 9 Documents clear
Uji Efektivitas Antimikroba Beberapa Merek Dagang Pembersih Tangan Antiseptik Radji, Maksum; Suryadi, Herman; Ariyanti, Dessy
Majalah Ilmu Kefarmasian Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In Modern life, peoples are more conscious to keep their healthy. One of the way to keep our body healthy is by keeping our hand clean. Washing hands with soap and water, sometimes is unpractical since it need water to rinse off the soap. Prod-uct innovation has been developed to overcome the unpractical side, which is called antiseptic hand wash or hand sanitizer. This study has been done to evaluate the antimicrobial activity of some hand sanitizer products marketed in Jakarta. The re-sult showed that alcohol-based hand sanitizer and triclosan-based hand sanitizer used in this experiment were significantly reduce bacterial counts on hands, but not all of the samples are effective in reducing fungal counts on hands.
Analisis Zat Warna Sintetik Terlarang Untuk Makanan Yang Beredar Di Pasaran Azizahwati, Azizahwati; Kurniadi, Maryati; Hidayati, Heidi
Majalah Ilmu Kefarmasian Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The use of synthetic food colorants is increasing because of its advantages. However, it is found that not all food colorants which are sold in the market are safe to be consumed. The purpose of this research was to identify synthetic food colorant samples which are sold in market and to find out whether they contain safe food colorants or not. Extraction did not need to be done on samples. Analysis was done using color reaction and paper chromatography. Densitometry was done to support the identification result. The result of this research showed that 10 out of 31 samples that were tested contain synthetic food colorants that must not be used for food. The ten samples were seven red colorants (three samples containing Merah K4, the two others containing Rhodamine B, and two samples containing Scarlet GN), one orange colorant (containing Orange G), one yellow colorant (containing Metanil Yellow) and one chocolate colorant (containing Chocolate Brown FB).
Pengaruh Pemberian Ekstrak Biji Klabet (Trigonella foenum-graecum L.) Terhadap Perkembangan Kelenjar Mamae Tikus Putih Betina Galur Wistar Agustini, Kurnia; Wiryowidagdo, Sumali; Kusmana, Dadang
Majalah Ilmu Kefarmasian Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Phytoestrogen is the chemical compound contains in plant which has estro-genic like effect. Estrogen has important function on woman’s sexual organ, such as proliferation of uterine and vaginal cornification. Phytoestrogen are weak agonists for estrogen and illicit statistic significantly increases in uterine wet weight, at definite dose, in uterothrophic bioassay. Biji Klabet or Fenugreek seed (Trigonella foenum-graecum L.) contains steroidal sapogenins such as diosgenin, tigogenin, gitogenin, yamogenin and trigoneoside, that suspected having an estrogen-like ef-fect or as phytoestrogen. The aim of this research was to investigate the estrogenic effect of fenugreek’s ethanolic extract in ovariectomized and immature rats models. These models represent the climacteric/menopause phase, where estrogen level is very low because ovary produces no estrogen. The testing animals were divided into normal group, ovariectomized control group, estradiol control group and three level doses of fenugreek extract (30mg/200gBW; 60mg/200gBW and 120mg/200gBW). The result indicated that start on 60mg/200gBW, fenugreek extract significantly could increasing mammary gland proliferation. Empirically fenugreek containing diosgenin, that caused breast enhancement. This research showed that treatment with fenugreek extract can caused proliferation of mammary gland, both on imma-ture and ovariectomized rats.
Uji Aktivitas Penghambatan Enzim A-Glukosidase Daun Kalanchoe Pinnata Pers Efizal, Efizal; Soemiati, Atiek; Hanafi, M; Dwiyanti, Indah
Majalah Ilmu Kefarmasian Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The study of inhibitory activity against the a-glucosidase enzyme of Kalanchoe pinnata Pers. leaves has been carried out. In vitro, the methanol extract, n-hexane fraction, ethyl acetate fraction and methanol-water (1:1) fraction inhibited a-glucosidase enzyme activities with IC50 value 72.8, 982.6, 194.6 and 293.8 ug/mL, respectively. In vivo, the study was conducted in normal ddY mice by using oral glucose tolerance test. The administration of methanol extract dose 0.5, 1.0 g/kg of body weight and ethyl acetate fraction dose 1.0 g/kg of body weight can suppress the blood glucose level at 30 min significantly (p<0.05) if compared with control after oral administration of sucrose (3 g/kg of body weight), and their activity were similar with acarbose 0.01 g/kg of body weight (p>0.05).
Kompleks Polielektrolit Kitosan-Xanthan sebagai Matriks Sediaan Mukoadhesif Setio Putri, Kurnia Sari; Sulistomo, Bambang; Surini, Silvia
Pharmaceutical Sciences and Research Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mucoadhesive dosage form is a pharmaceutical dosage form with prolonged gastric residence time which can increase bioavailability of drugs. An excipient with suitable swelling and bioadhesive characteristics plays important role to obtain good mucoadhesive dosage form. Our pre-eliminary study showed that chitosan-xanthan gum polyelectrolyte complex (CXPC) in ratio 1:1 exhibit suitable swelling index to be developed as mucoadhesive dosage forms. This research was performed to study CXPC characteristics as matrix for mucoadhesive granules dosage form matrix. In this study CXPC 1:1 was utilized as the matrix in the mucoadhesive granules with drug-CXPC ratio of 1:1, 1:2, and 1:3, using diltiazem HCl as a drug model. The granules were prepared by wet granulation method, and the in vitro bioadhesive properties of the granules, as well as the drug release profile, were evaluated. The results showed that formula containing diltiazem HCl and CXPC in ratio of 1:2 possessed a good bioadhesive ability up to 8-12 hours and showed controlled drug release profile up to 8 hours. The results can be concluded that the CXPC is a suitable excipient as a mucoadhesive matrix.
Skrining dan evaluasi aktivitas kitinase dari sembilan isolat bakteri lokal Maggadani, Baitha Palanggatan; Setyahadi S, Siswa; Harmita, Harmita
Pharmaceutical Sciences and Research Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chitinase is an enzyme that degrades chitin on β-1,4-acetamido-2-deoxy-D-glycoside bound to produce Chitin oligosaccharide or its soluble monomer, N-acetylglucosamine (NAG). Chitinase are usually produced naturally by chitinolytic microorganism that are found in soil or water environment. Chitinase have been widely used for biocontrol agents of plant pests. The product from chitinase hydrolysis can be used as antiinflammatory agent and anti hyperpigmentation. This research was aimed to screen and evaluate the chitinolytic ability of 9 isolate. The best isolate was the one which produced high chitinolytic activity and hydrolyzed chitin into NAG. 9 isolate were examined and BPPTCC-2 was the best isolate which produced highest level of chitinolytic activity 0.1780 U/ml. The chitinase was able to hydrolyzed chitin resulting high yields of NAG 11.5% as the only product.
Perbandingan Efektifitas Antara Minyak Atsiri Kulit Batang Kayu Manis (Cinnamomum burmannii) dengan Temephos sebagai Larvasida Aedes aegypti Al Kamal, Muhamad Rizki; Syafei, Neneng Syarifah; Nasution, Gita Tiara Dewi
Pharmaceutical Sciences and Research Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Dengue fever is a major health issue in the world. Preventive measure with temephos/abate has long been used to combat this problem. Istiana et al reported that there were cases of resistance of Aedes aegypti larvae to temephos in various parts of the world, including Indonesia. Indonesian Cinnamon (Cinnamomum burmannii) has been proven to possess larvacide effect and can be used as an alternative insecticide. This research was meant to compare the larvacide effect of Indonesian cinnamon (Cinnamomum burmannii) essential oil to the larvacide effect of temephos against Aedes aegypti larvae. This research used laboratory experimental design analysis. The total number of samples were 20 larvae of Aedes aegypti at 3rd and 4th instar which were tested four times on each four experimental groups. The collected data were the total number of Aedes aegypti larva deaths observed 24 hours after the variables were applied. The analysis of the results was done by using statistic analysis program. There were significant differences on larva deaths due to the essential oil and abate variables with p value < 0.001. The results were as follows: negative control death (0%), emulsifier (2.5%), essential oil (22.5%), and abate (100%). The larvacide effectiveness of abate is significantly better than that of Indonesian cinnamon essential oil.
Parameter Fisikokimia dan Analisis Kadar Allyl Disulfidedalam Ekstrak Etanol 70% Bawang Putih (Allium sativum L.)dengan Perbandingan Daerah Tempat Tumbuh Parameter Prastiwi, Rini; Siska, Siska; Marlita, Nila
Pharmaceutical Sciences and Research Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Garlic (Allium sativum L.) is one of the medicinal plants that has a potential to be developed to become a traditional medicine. Traditional medicinal products and medicinal plants which have good quality are determined by the quality and safety of the extract. One of many factors that can affect the quality is the growing area. This research aimed to compare the value of physicochemical parameters as well as the levels of compounds responsible for pharmacological activity in ethanol 70% extract of garlic obtained from two growing areas, Bogor and Wonosobo. The test results obtained from garlic extract of Bogor were: compound contents dissolved in water was 62.5684%, compound contents dissolved in ethanol was 10.0779%, essential oils contents was 0.7477%, levels of allyl disulfide was 1.8322%, total ash content was 2.3529%, ash content insoluble in acid was 0.1115%. While the test results obtained from garlic extract of Wonosobo: compound contents dissolved in water was 59.0007%, compound contents dissolved in ethanol was 8.9230%, essential oils contents was 0.3400%, levels of allyl disulfide was 1.6542%, total ash content was 3.0196%, ash content insoluble in acid was 0.4974%. Based on those results, the best quality extract was garlic from Bogor with higher specific parameter values and lower non-specific parameter values.
Hubungan Kesesuaian Penulisan Resep dengan FormulariumNasional Terhadap Mutu Pelayanan pada Pasien JaminanKesehatan Nasional di Rumah Sakit Umum di Bandung Pratiwi, Winda Ratna; Kautsar, Angga Prawira; Gozali, Dolih
Pharmaceutical Sciences and Research Vol. 4, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pharmaceutical service is one of the activities in hospital that support health service quality. One of the factors that can improve quality of pharmaceutical services is prescription services. In the era of National Health Insurance, prescription given to the patients should be based on the National Formulary. If prescriptions did not suit the national formulary, it would influence the services quality on pharmacy unit. The purposes of this study were to determine suitability of prescription outpatients’ national health insurance with national formulary and to determine the relationship of the suitability of prescription with a national formulary to service quality in pharmacy unit in one of general hospitals in Bandung. A cross sectional with servqual questionnaire was used to the patients and the 262 prescription samples needed were taken in January 2017. Mann Whitney test is used for bivariate analysis. The result indicated 91.7% prescriptions was suited the national formulary and the rest was not. There was a significant difference between prescription suitability with the national formulary to service quality in pharmacy unit in the hospital with p-value 0.00 (p < 0,05). It can be concluded that higher percentage of prescriptions suitability with the national formulary in hospital related with the better service quality of pharmacy unit.

Page 1 of 1 | Total Record : 9

 1 

Filter by Year

2007 2017


Reset
Filter By Issues
All Issue Vol. 12, No. 2 Vol. 12, No. 1 Vol. 11, No. 3 Vol. 11, No. 2 Vol. 11, No. 1 Vol. 10, No. 3 Vol. 10, No. 2 Vol. 10, No. 1 Vol. 7, No. 4 Vol. 9, No. 3 Vol. 9, No. 2 Vol. 9, No. 1 Vol. 8, No. 3 Vol. 8, No. 2 Vol. 8, No. 1 Vol. 7, No. 3 Vol. 7, No. 2 Vol. 7, No. 1 Vol. 6, No. 3 Vol. 6, No. 2 Vol. 6, No. 1 Vol. 5, No. 3 Vol. 5, No. 2 Vol. 5, No. 1 Vol. 4, No. 3 Vol. 4, No. 2 Vol. 4, No. 1 Vol. 3, No. 3 Vol. 3, No. 2 Vol. 3, No. 1 Vol. 2, No. 3 Vol. 2, No. 2 Vol. 2, No. 1 Vol. 1, No. 3 Vol. 1, No. 2 Vol. 1, No. 1 More Issue