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International Journal of Health and Pharmaceutical (IJHP)

IJHP
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Published by CV. Inara

ISSN : - EISSN : 2808845X DOI : https://doi.org/10.51601/ijhp

Core Subject : Health,

Nursing Public Health

International Journal of Health and Pharmaceutical (IJHP) e- ISSN : 2808-845X is a communication media and scientific publication in the health and pharmaceutical fields published by Inara Publisher. International Journal of Health and Pharmaceutical (IJHP) contains articles from research focusing on basic medicine, clinical medicine, epidemiology, preventive medicine (social medicine), pharmacy, and other medical fields. International Journal of Health and Pharmaceutical (IJHP) is published periodically four times a year (February, May, August and November).

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 426 Documents

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Bioautographic Analysis And Antibacterial Activity Test Of Mengkudu Leaf (Morinda Citrifolia L.) Ethanol Extract On The Bacteria Propionibacterium Acnes Rati Satri Situmorang; Haris Munandar Nasution; Minda Sari Lubis; Yayuk Putri Rahayu
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Noni contains alkaloids, flavonoids, tripertinoid, protein, lime, iron, carotene, glycosides antarkiron. The content of anthraquinin, scaloptin, flavonoid and adaptogen compounds are active compounds that have antifungal and antimicrobial effects. The antibiotics commonly used are antibiotics such as tetracycline, clindamycin and others. These chemical-based antibacterials have many negative side effects, therefore other alternatives are needed as antibacterials, one of which is by using noni. This study aims to analyze bioautography and determine the antibacterial activity of noni leaf ethanol extract against Propionibacterium acnes bacteria.This research was conducted experimentally using noni leaf ethanol extract with concentrations of 30%, 40%, 50% as independent variables and bioautographic analysis and antibacterial activity as dependent variables. The bioautography analysis was performed using TLC and the antibacterial activity test was performed using paper discs.The results of antibacterial testing of noni leaf ethanol extract with a concentration of 30% had an inhibition zone of 8.36 mm with a medium category, a concentration of 40% had an inhibition zone of 10.3 mm with a strong category and a concentration of 50% had an inhibition zone of 11.1 mm in a strong category. positive control tetracycline 30µg had an inhibition zone of 20.8 mm which was categorized as very strong. The results of the bioautography test using contact bioautography using the mobile phase of chloroform: n-hexane (7:3). The inhibition zone was obtained at an Rf value of 0.17, and the characteristics of the chromatogram spots were carried out by spraying 10% FeCl3 suspected that the spots were flavonoid compounds.

Bioautographic Analysis And Antibacterial Activity Test Of Curry Leaf (Murraya Koenigii (L) Spreng) Ethanol Extract On The Bacteria Propionibacterium Acnes Muhammad Wahyu Ikhsan Muhammad Wahyu Ikhsan; Haris Munandar Nasution; Yayuk Putri Rahayu; M. Pandapotan Nasution
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Curry leaf (Murraya koenigii (L) Spreng) is one of the plants known to have antibacterial compounds. Curry leaves are also known as temurui leaves and are useful as a natural food flavoring. Curry leaves contain flavonoid compounds, alkaloids, calcium, zinc, riboflavin, folic acid. This study aimed to analyze the bioautography and antibacterial activity of ethanol extract of curry leaves against Propionibacterium acnes bacteria. The research method was carried out experimentally. Curry leaf simplicia extract was made with 96% ethanol as solvent. Curry leaf ethanol extract was made in various concentrations, namely 30%, 40% and 50%. The positive control used was Tetracycline HCl and the negative control was DMSO. The tests carried out on curry leaf simplicia included phytochemical screening, macroscopic examination, microscopic examination, water content examination, examination of water soluble extract content, examination of ethanol soluble extract content, examination of ash content and examination of acid insoluble ash content, bioautographic analysis he results of phytochemical screening showed that curry leaves contain secondary metabolites, namely flavonoids, alkaloids, tannins, saponins, steroids/triterpenoids, and glycosides. The results of the antibacterial activity showed that curry leaves could be used as antibacterial because they had strong inhibition at concentrations of 30%, 40% and 50%, namely 10.3 mm, 11.7 mm and 13.6 mm against P. acnes bacteria. The results of bioatuography showed that the Rf value in the clear zone was 0.17 with a ratio of chloroform:n-Hexane (8:2) on the chromatogram spots by spraying 10% FeCl3 positive for flavonoid compounds which were marked in black.

Characteristics Of Family Support With Anxiety Levels For Palliative Cervical Cancer Patients At dr.Chasan Boesoerie Ternate City Nursia Aja; Didik Kurniawati
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Cancer is a disease caused by abnormal growth of cells body tissue that is in the body changes into cancer cells. The purpose of this study was to study the characteristics of family support and anxiety levels of palliative cervical cancer patients at dr. Chasan Boesoerie, Ternate City. This type of research is an analytical observational study with a cross-sectional cross-sectional technique, to describe and assess several characteristics of family support with anxiety levels of palliative cervical cancer patients. The population in this study were all mothers who examined cervical cancer at dr. Chasan Boesoirie 2021, 47 mothers. The sampling technique was carried out with the total sample. That is equal to 47 mothers with cervical cancer. Results: The results of the study show that the age of mothers who are not at risk is 66.0%, while the frequency of respondents with civil servant jobs is 40.4%, compared to the work of IRT/Not Working mothers of 10.6%, compared to good knowledge of 61, 7% compared to the knowledge of the mother less by 38.3%, and good family support by 55.3% compared to the less family support by 44.7%, while the greater source of information is in the newspapers by 66.0% compared to social media, namely by 34.0%. Conclusion: There needs to be cooperation from health workers, for example from hospitals, always providing information about cervical cancer, always checking regularly with obstetricians to avoid things that can trigger disease growth and can prevent cancer triggers.

Analysis Of Factors Affecting The Acceptance Of Hospital Information System Using Utaut Method In Budi Kemuliaan Hospital Batam Year 2021 Lenny Simatupang; Irma Solvia; Karmila Kaban; Sri Lestari Ramadhani Nasution
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

The acceptance of the hospital information system using the UTAUT method at the Budi Kemuliaan Hospital Batam in 2021 is still a complaint and the computer-based SIMRS is not running optimally. The acceptance of the hospital information system using the UTAUT method is related to individual characteristics, performance expectations, business expectations, social and facilities. This study aims to determine the effect of receiving hospital information systems with the UTAUT method at Budi Kemuliaan Hospital Batam. This type of quantitative research with correlational techniques. The population in this study were users of the SIMRS application at Budi Kemuliaan Hospital Batam and a sample of 120 people. The collection of data with primary and secondary data and the data were analyzed by Multiple Regression test. The results showed a positive and significant influence between Hospital Information System Acceptance (individual characteristics, performance expectations/performance expectations, business expectations/business expectations, social influences/social influences, and facilitating conditions/facilitating conditions) on usage behavior/behavior. implementing SIMRS with the UTAUT method at Budi Kemuliaan Hospital Batam and it is recommended that the implementation of SIMRS then need to pay attention to the ease of users in using SIMRS and developers from SIMRS and the hospital need to work together in developing to create a SIMRS with business processes and needs the one in the hospital.

Drug Management On Availability Of Drugs In Pharmaceutical Installations Pabatu General Hospital Pt Pmn Using Fifo & Fefo Methods Josua Pranata; Karmila Kaban; Maya Sari Mutia; Ulina Karo Karo
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

The procurement of drugs is an important early stage in determining the success of the next stage because the planning stage is useful for adjusting the procurement needs with available funds to support health services in hospitals. The purpose of the study was to analyze the Management of Procurement of Insurance Medicines and Medicines for BPJS Health in the Pharmacy Unit of Bakti Timah Hospital, Pangkal Pinang, Bangka Belitung Islands Province in 2022. The research design used a qualitative descriptive method with a phenomenological approach, namely collecting, compiling, and analyzing so that a social phenomenon/fact can provide information. solving the problems encountered. This research was conducted at the Pharmacy Unit of Bakti Timah Hospital, Pangkal Pinang, Bangka Belitung Islands Province in April-May 2022. The sampling technique in this study used the Total Sampling technique, the number of samples was 5 pharmacists. The results of the research on the drug planning process at the Bakti Timah Pinang Hospital Pharmacy Installation, the drug budgeting process at the Bakti Timah Pinang Hospital Pharmacy Installation, the drug procurement process at the Bakti Timah Pinang Hospital Pharmacy Installation, the drug storage process at the Bakti Timah Pinang Hospital Pharmacy Installation, The process of storing drugs at the Pharmacy Installation of the Bakti Timah Pinang Hospital. Suggestions for hospital management to find out what strategies should be applied to increase revenue and services by reducing the percentage of prescriptions that are not served.

Quality Analysis Of Nursing Services Towards Internal Disease Inpatient Satisfaction At The Prima Indonesia Royal Hospital During The Covid-19 Pandemic Of 2021 Andre Jonathan Samuel Gultom; Wienaldi Wienaldi; Maya Sari Mutia; Ali Napiah Nasution
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

The Covid-19 pandemic has caused a decrease in the number of patient visits and changes in service procedures for patients being treated to prevent transmission of Covid-19. This has an impact on decreasing patient satisfaction with service quality which includes physical evidence, reliability, responsiveness, assurance, and empathy. The purpose of this study was to analyze the quality of nursing services on the satisfaction of internal medicine inpatients during the Covid-19 pandemic. This research is a quantitative analytic study with a crosssectional approach. The research was conducted at the Royal Prima Hospital, Medan. Theresearch population was 285 people, the sample obtained was 166 people. Sampling by purposive sampling. Data analysis was univariate, bivariate with a chi-square test, and multivariate with multiple logistic regression at a 95% confidence level (α = 0.05). The results showed that the quality of nursing services affected the satisfaction of inpatients for internal medicine at the Royal Prima Hospital Medan during the Covid pandemic including physical evidence (p = 0.000), and reliability (p = 0.008), responsiveness (p = 0.001), and assurance. (p=0.000). While the factor that has no effect is empathy (p = 0.959). The physical evidencevariable (tangibles) is the most dominant variable affecting the satisfaction of internal medicine inpatients during the Covid-19 pandemic with a value of Exp(B)/OR = 13,773. Patients who stated good physical evidence had a 13.7 times higher chance of being satisfied than patients who stated poor physical evidence

Recommendations For Improving Exclusive Breast Milk For Working Mothers With Health Action Process Approach (Hapa) In Batu Bara District Elza Fahliza Ismar; Herisa Putri Anggraini; Ermi Girsang; Ali Napiah Nasution; Putranto Manalu
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Mother's Milk (ASI) is the main and best food for babies that have no equal. The benefits of exclusive breastfeeding are enormous, especially for the baby's growth and development, immunity, psychology, and the economy of the baby's parents. Even though the benefits of exclusive breastfeeding are clear for mothers and their babies, the coverage of exclusive breastfeeding for babies is still low. The purpose of this study was to analyze the increase in exclusive breastfeeding for working mothers using the Health Action Process Approach (HAPA) in Batu Bara Regency. The sample of this research is working mothers who have babies 0-6 months in Batu Bara Regency. The sampling technique is Non-Probability Sampling using Total Sampling, where the number of samples is the same as the population of 100 people. The data processing method used Univariate, Bivariate, and Multivariate tests. Theresults showed that self-efficacy, outcome expectations, risk perception, planning, the effect of intention, maintenance, and planning strategies to overcome barriers had a significant effect on breastfeeding practices for working mothers in Batu Bara Regency as evidenced by the p-value of each variable 0.000 <0.05. The multivariate test results show that together the independent variables have a significant effect on the dependent variable, with the most dominant variable being the maintenance variable with an average value of 10.66. The frequency of exclusive breastfeeding and the duration of breastfeeding has no effect on the practice of breastfeeding for working mothers in Batu Bara Regency.

Formulation Of Anti-Acne Extract Aloe Vera (Aloe vera (L.) Burm.f.) In Hibiting The Activity Of Propionibacterium acnes Mohd. Bilal; Minda Sari Lubis; Rafita Yuniarti; Haris Munandar Nasution
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 2 (2023): May 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i1.140

Aloe vera (Aloe vera (L.) Burm.f.) is widely used as an alternative medicine to treat various types of diseases and is now widely used as an antibacterial, one of which is against the acne bacteria Propionibacterium acnes. The purpose of this study was to determine the gel preparation of aloe vera extract (Aloe vera (L.) Burm.f.) which has activity against Propionibacterium acnes and to see if the gel preparation produced has good and stable quality. Aloe vera ethanol extract was made by maceration method, then the extract was made in a gel preparation and then tested for antibacterial activity against Propionibacterium acnes by the agar diffusion method using several concentration variations: 2.5%, 5%, and 10%. Furthermore, the inhibitory power of 2.5% has a medium category, the inhibition of 5% has a medium category, and the inhibition of 10% has a strong category. then tested for organoleptic, homogeneity test, pH dispersion and physical stability of the preparation. The results of the study showed that the gel preparation of aloe vera extract had antibacterial activity against Propionibacterium acnes, namely a concentration of 2.5% inhibition zone of 8.8 mm including the medium category, 5% concentration of the inhibitory zone of 9.8 mm including the medium category, the concentration of 10 % with an inhibition zone of 12.9 mm including the strong category. The conclusion of this study is that the gel preparation of 10% aloe vera ethanol extract concentration has the best inhibition. Then the stability test was then carried out, which included, the organoleptic did not change significantly, the homogeneity test showed good results, while the dispersion test showed good results, and the pH test showed good results according to skin pH.

Phytochemical Screening And Antioxidant Activity Testing Of Porang (Amorphophallus Muelleri Blume) Leaf Ethanol Extract From Kuta Buluh Region, North Sumatera Ainil Fithri Pulungan; Ridwanto Ridwanto; Gabena Indrayani Dalimunthe; Zulmai Rani; Rahma Dona; Ricky Andi Syahputra; Robiatun Rambe
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Porang (Amorphallus muelleri Blume) is one type of tuber plant that has the potential to be developed in Indonesia. Porang plants have been reported to contain chemical compounds that have antioxidant activity. This research was conducted on the leaves of the porang plant with the aim of knowing the antioxidant activity, characterization, and phytochemical profile of the compounds contained therein. Compound identification and characterization were performed using standard methods, and antioxidant activity was determined using the DPPH (1,1- Diphenyl-2-picrylhydrazyl ) method. The results of the identification of chemical compounds showed that the ethanol extract of porang leaves contained chemical compounds of alkaloids, flavonoids, tannins, saponins, and steroids. The results of the examination of the simplicia characterization of porang leaves included the soluble ethanol content of 33.93%, the water soluble extract content of 17.3%, the ash content of 5.58%, the acid insoluble ash content of 0.235% and the water content of 8%. From the results of the simplicia characterization, it shows that the results meet the specified requirements. The results showed that the ethanol extract of porang leaves had antioxidant activity with an IC50 value of 93.04 µg/mL, which in this case is included in the category of strong antioxidant activity. Meanwhile, as a comparison, Vitamin C was used, which has an IC50 value of µg/mL, which is included in the category of very strong antioxidant activity.

Analysis Of Potential Drug Interactions In Prescribing Type 2 Diabetes Mellitus Patients At A Pharmacy In Medan City Kiki Rawitri Kiki; Sri Wahyuni; Syilvi Rinda Sari
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Multiple drugs or polypharmacy received by patients with diabetes mellitus (DM) during therapy can trigger drugrelated problems, one of which is drug interactions. The occurrence of drug interactions causes uncontrolled blood sugar levels which can affect the patient's morbidity, mortality, and quality of life. This study aims to look at the description of potential drug interactions in prescribing type 2 DM patients at a Pharmacy in Medan City for the period January-April 2022. This study is a descriptive study and data were taken retrospectively on 126 prescription sheets for type 2 DM patients who met the inclusion criteria. Identification of potential drug interactions using online literature such as Medscape Drug Interaction Checker, Drugs.com, and Drug Interaction Fact 2009 e-book. Data analysis was carried out univariately to describe the percentage of drug interactions. The results showed that from 126 prescription sheets for type 2 DM patients there were 108 patients (85.71%) who had the incidence potential drug interactions with a total of 238 potential drug interactions. The number of potential drug interactions based on the mechanism of action, namely pharmacodynamic interactions were 117 events (49.15%), pharmacokinetic interactions were 22 events (9.24%), and unknown were 99 events (41.61%) with The severity level was severe (major) with 1 event (0.42%), moderate (moderate) with 223 events (93.69%) and mild (minor) with 14 events (5.89%). Based on the results of the study, it was concluded that an analysis of 126 patients with type 2 diabetes mellitus, there were found 108 (85.71%) prescriptions to potential antidiabetic interactions.

Page 12 of 43 | Total Record : 426

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Contact Name Arman Harahap

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Editorial Address Jl. SM. Raja, No 27, Kab. Labuhanbatu, Provinsi Sumatera Utara, 21419

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Arman Harahap

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armanhrahap82@gmail.com

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+6285370005518

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armanhrahap82@gmail.com

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Jl. SM. Raja, No 27, Kab. Labuhanbatu, Provinsi Sumatera Utara, 21419

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