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Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga.
Published by Universitas Muhammadiyah Malang
ISSN : 0216759X     EISSN : 2614476     DOI : https://doi.org/10.22219/
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Journal of Saintika Medika is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Letters and commentaries of our published articles are welcome.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 564 Documents
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Correlation Between Knowledge Level On Anxiety Level Post-Coronavac Vaccine at The Clinic of dr. Irma Marintik Ilahi; Yusrin Aulia
Saintika Medika Vol. 17 No. 2 (2021): December 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM2.18300

Abstract

Vaccination is the government's effort to prevent the spread of the COVID-19 pandemic. Lack of knowledge about the Coronavac vaccine gives rise to various kinds of speculation, resulting in anxiety. This study attempts to analyze evaluate the correlation between knowledge level of public officers about the effects of Coronavac vaccine on anxiety level post-Coronavac vaccine at the dr. Irma Clinic.The study was an analytic observational study with a cross-sectional design, conducted on March 22, 2021. 62 public officers who received the Coronavac vaccine at the dr. Irma Clinic was enrolled. The sampling technique used was total sampling. The data analysis used was the Mann-Whitney test.The result showed that 39 (62.9%) respondents had a good level of knowledge. 42 (67.7%) respondents showed no sign of anxiety. There was a tendency that the better the level of knowledge, the less anxious, and vice versa, the less knowledge, the more respondents experience both mild and moderate anxiety. From the Mann Whitney test results, the p-value was 0.000 (sig < 0.05).There was significant correlation between knowledge level of public officers about the effects of Coronavac vaccine on anxiety level post-Coronavac vaccine at the dr. Irma Clinic.
Pregnant Women’s Factor toward Motherto-Child Transmission of HIV practice Prihanti Gita Sekar; Irma Nur Sukmawati; Firman Arief; Qonita Prasta A; Enggar Ayu S; Jeanny Dwi Adriyanti; Iqbal Margi S
Saintika Medika Vol. 17 No. 2 (2021): December 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM2.18536

Abstract

In 2005 , there are 700.000 people infected with HIV each day around the world. Among those 200.000 are children under 15 with the highest mortality rate within those under 1 year old. According to the official guideline of released by Indonesian Ministry of Health 2011, strategies to prevent vertical infection of HIV has to be done comprehensively in order to reduce the risk to a minimum. This study aim to identify the factors of pregnant women toward mother-to-child transmission (MTCT) of HIV practice. A Cross-Sectional study design with observational analytic was conducted in this study and involving 138 pregnant woman. Data analysis used Chi-Square, Kruskal Wallis,  Mann Whitney andLogistic Regression Analysis. Multivariate analysis showed age variable, education, and attitude affect the MTCT of HIV practice significantly(age p: 0.012, OR: 0.057, CI: 0.006-0.533; education p: 0.027, OR: 0.137, CI: 0.023-0.802; attitude p: 0.012, OR: 0.224, CI: 0.069-0.725). The data showed R2 31.6% that means the MTCT of HIV practice affected by age, education and attitude, meanwhile the rest (68.4%) is affected by another factors that did't identified yet in this study.
The Effect Of Papaya Leaf Extract (Carica Papaya L) On Methemoglobin Percentage And The Number Of Erythrocyte Cells In Wistar Strain White Male Rats Induced With Sodium Nitrite Diah Hermayanti; Hawin Nurdiana; Jessica Alda
Saintika Medika Vol. 17 No. 2 (2021): December 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM2.18803

Abstract

Sodium nitrite is widely used nowadays, especially in the meat processing industry. In the case of an overdose, it can cause poisoning, which causes the oxidation of the iron component in the hemoglobin of erythrocytes to methemoglobin, thereby damaging cell membranes and hemolytic. Papaya leaves contain antioxidants that can inhibit the oxidation of iron components in hemoglobin. To determine the effect of papaya leaf extract on methemoglobin levels and the number of erythrocytes in white male Wistar rats strain induced with sodium nitrite. True experimental research design using post test only control group design. The object of this study was male white rats (Rattus novergicuswistar strain) induced intraperitoneally with sodium nitrite. The study was divided into a negative control group, a positive control group, a treatment group with a dose of papaya leaf extract PI (0.7 ml/200 g BW), PII (1.4 ml/200 g BW), PIII (2.8 ml/200 g BW). BB). Kruskal-Wallis test, methemoglobin levels sig. 0.001 (p<0.05). One wayannova test, erythrocyte cell count sig. 0.021 (p<0.05). Post Hoc test there was a significant difference between the negative control group and the positive control group on all variables, not different from the PII group for methemoglobin levels, not significantly different from the three treatment groups for the number of erythrocytes. Papaya leaf extract contains antioxidants that can inhibit the formation of methemoglobin, and maintain the number of erythrocytes. Papaya leaf extract can inhibit the formation of methemoglobin, maintain the number of erythrocytes in male Wistar strain rats induced with sodium nitrite.
Synergistic Potential Of Bioactive Compounds Of Nut Grass Tuber Extract (Cyperusrotundus) As Anti-Leukemia Herbal Medicine Agustini, S. M.; Tri Aini Fadjrin Juliani; Nimim; Patmawati
Saintika Medika Vol. 17 No. 2 (2021): December 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM2.18805

Abstract

Leukemia treatment strategies have developed rapidly. Both the intensity of the dose and the duration of intensive treatment have been maximized after decades of trials optimizing chemotherapy options, dose intensity, and duration of treatment. The emergence of multidrug-resistant cancer cells (MDR) results in the higher costs needed in the treatment of AML patients. The purpose of this study was to identify and evaluate the potential of active compounds from Cyperus rotundus on the activity of the Acute Myeloid Leukemia (AML) cell line HL-60 APL through inhibition of proliferation, cell cycle, differentiation, and induction of apoptosis in the treatment of AML. The bioavailability of the compound to be taken orally was analyzed by Human Intestine Absorption (HIA+). Potential pathways inhibiting proliferation, cell cycle, differentiation, and induction of apoptosis in the treatment of AML were analyzed using a Structure-Activity Relationship approach with the PASS SERVER program. Pathway analysis was carried out using STITCH and Cytoscape v.3.5.1 programs. The study results showed that nutgrass has six active compounds quercetin, luteolin, apigenin, camphor, sitosterol, and gallic acid, synergizing the main pathway of cell activity (Pa>0.7).Conclusion of Cyperus rotundus extract has a high potential synergistically as an anti-leukemia herbal medicine.
Antimicrobial potential of Kaffir Lime (Citrus hystrix D.C) peel extract against Staphylococcus aureus Ginda Nabila Choirunnisa; Kanti Ratnaningrum; Ika Dyah Kurniati
Saintika Medika Vol. 18 No. 1 (2022): June 2022
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol18.SMUMM1.21112

Abstract

Staphylococcus aureus is a normal bacterial flora that can cause skin infections such as boils, acne, impetigo and is also a major cause of nosocomial infections. This study examined the effect of kaffir lime (Citrus hystrix D.C) peel extract on Staphylococcus aureus. This research was a true experimental study with a post test only control group design. Kaffir lime peel was extracted using maceration method with 70% ethanol solvent, then diluted using 2ml ethanol to a concentration of 25mg/ml, 20mg/ml, 15mg/ml, 10mg/ml and 5mg/ml. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were conducted to assess the kaffir lime peel extract against Staphylococcus aureus bacteria. The MIC test was measured using a spectrophotometer in the liquid dilution method and MBC test was carried out using solid dilution on Mueller Hinton media. Minimum Inhibitory Concentration of kaffir lime peel extract against Staphylococcus aureus bacteria at a concentration of 20mg / ml., while MBC in this study could not be determined because at a concentration of 25% there was still colony growth in repetitions 1 and 2.
The Effect of Brain Training Game activities on Improvement of Cognitive Function measured by Montreal Cognitive Assesment Indonesia version (MoCA-Ina) Mochamad Bahrudin; Adni Pratiwi; Anang Bayu Seta; Risma Karlina Prabawati
Saintika Medika Vol. 18 No. 1 (2022): June 2022
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol18.SMUMM1.21569

Abstract

The function of cognition in young adults (around the age of 20 years) mostly does not develop to its peak, even though at that age a person needs better cognitive abilities to deal with the lectures. Brain training game activities by playing games through the NeuronationTM application can improve cognitive function. To determine the effect of Brain training activities on improvement of cognitive function. Experimental study with two group pre and post design. 74 Sample were medical students of Faculty of Medicine, University of Muhammadiyah Malang class of 2017-2018, divided into control and treatment groups of 37 samples each. The treatment group was given by game brain game training 30 minutes a day, 20 times in 4 weeks.. Cognitive function was measured by the MoCA-Ina test in the control group and pre and post test. The hypothesis test used the pairet samples test. Cognitive function of pre and post test of the control group good cognitive function increased 2.69% and cognitive function of pre and post test of treatment group increased 58.8% with the result of pairet sample analysis of significant p = 0,000 which means that in the control group there was a tendency for increased function cognition after treatment (post test) but the improvement was not significant. In the treatment group with brain training activities cognitive function increased sharply and statistically significant, Brain training activities affect the improvement of cognitive function.
Overview of Ear, Nose, and Throat Complaints of Covid 19 Inpatients at the University of Muhammadiyah Malang Hospital for the Period April 2021 to June 2021 Nimim Putri Zahara; Indra Setiawan; Jauhar Tajudin
Saintika Medika Vol. 18 No. 1 (2022): June 2022
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol18.SMUMM1.21604

Abstract

Covid-19 is spreading rapidly to other countries, and WHO confirmed it as a pandemic disease in March 2020. The virus enters directly to the surface of the mucosa with a high viral load, so it is clear that complaints in the nose and throat area are found. Covid-19 initially appears mainly in the airway with symptoms can be fever and dyspnea cough which can quickly switch to acute respiratory distress syndrome. RSU Universitas Muhammadiyah Malang has been one of the Covid-19 referral hospitals in East Java since April 2020, and there is no data on the description of nasal ear and throat complaints (ENT) in Covid-19 hospitalization patients at UMM Hospital. Mengetahui overview and overview of nose and throat ear complaints (ENT) experienced by Covid-19 hospitalized patients at UMM Hospital in the period April 2021 to June 2021. Descriptive retrospectively by taking data from the medical records of Covid-19 hospitalization patients of UMM Hospital in the period April to June 2021 with a total sampling method of 161 hospitalized patients with a confirmed diagnosis of Covid-19 with PCR examination during the period of April to June 2021. The study was conducted on 161 medical records with the results of 84 patients were men with 21 patients with severe degrees, 63 patients with moderate degrees, and 77 patients were women with 18 patients with severe degrees and 59 patients with moderate degrees. Mortality rates were obtained in as many as 26 (16%) with varying age ranges; 78 (48%) patients had comorbidities, with Diabetes mellitus as the highest comorbid among as many as 31 (40%) patients. Patients with ENT complaints were obtained among as many as 95 (60%) patients, and 66 (40%) patients were not accompanied by ENT complaints. The three most ENT complaints were colds (rhinitis) in as many as 62 (39%) patients, anosmia hyposmia in as many as 26 (16%) patients, and throat pain in as many as 22 (14%) patients. Most patients were men with moderate degrees, with mortality rates of 16% and 48% of patients accompanied by comorbidities. The most ENT complaints were rhinitis 39%, anosmia-hyposmia 16%, and throat pain in as much as 14% of patients.
Pesticide Exposure to Liver Function of Farmers in Rural and Remote Areas in Indonesia: A Correlational Study Rafi'ah Rafi'ah; Iga Maliga; Gladeva Yugi Antari
Saintika Medika Vol. 18 No. 1 (2022): June 2022
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol18.SMUMM1.17931

Abstract

Farmers are exposed to pesticides that impact liver function disorders, especially during the pesticide spraying process. Several studies have shown that there is a link between liver damage associated with pesticide use. This study aims to compare the intensity of pesticide exposure to the liver function disorders of farmers. Farmers in this study were divided into two groups, namely farmers in rural areas and remote areas. This study is a quantitative descriptive study with a cross-sectional study approach. This research was conducted in April - August 2020 in Indonesia, involving 40 farmer respondents from rural and remote areas in Sumbawa Regency, Indonesia. The results show that chi-square table values of length of time working as farmers, a spraying method, and smoking habits less than chi-square calculated so that they are no correlations with the highest amount of S.G.O.T. and S.G.P.T. The chi-square value shows a relationship between the use of P.P.E. with A.S.T. levels but not with the S.G.P.T. value. The S.G.P.T. value in both groups indicates a relationship between the S.G.P.T. level and P.P.E. because of the Chi-Square table value <the calculated Chi-Square value. The results showed that the length of time working as a farmer, spraying method, and smoking habits had no correlation with high levels of S.G.O.T. and S.G.P.T. among farmers in rural and remote areas. Then the use of P.P.E. that is not right affects the levels of S.G.O.T. and S.G.P.T. in farmers.
Depression Among University Students During Covid-19 Pandemic: An Online-Based Cross-Sectional Study Ranti Ekasari; Ahmad
Saintika Medika Vol. 18 No. 1 (2022): June 2022
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol18.SMUMM1.18472

Abstract

COVID-19 is a new communicable disease that spread all over the world and becomes a pandemic. It also caused psychological conditions like depression. Students were one of the groups who have a high opportunity to get depressed. Since students are in a transitional period of early adulthood, they are facing another form of adjustment that can trigger depression.This study aimed to know the depression level of students at Universitas Islam NegeriAlauddin Makassar and some factors that were thought to have a relation to the depression level.This is quantitative research, in which a cross-sectional study design used primary data taken from August 1 until August 12, 2021, via a Google Form. The total sample was 344 respondents.Most of the respondents tend to have normal levels of depression. Age, gender, period of learning, and learning challenges were being the variable that had a significant correlation with depression level. Whilst, faculty and learning media had not.In order to tackle down the depression of students, it is necessary to have the cooperation of various parties, including from the campus, the family, and the role of students in managing information.
Relationship Between Disease Stadium And Quality Of Life In Parkinson's Disease Patients In The Neural Polyclinic Of Muhammadiyah University Hospital Malang Sigit Hari Nursyamsu; Rachmanita Charisma Putri; Risma Karlina Prabawati; Feny Tunjungsari Tunjungsari
Saintika Medika Vol. 18 No. 1 (2022): June 2022
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol18.SMUMM1.21198

Abstract

Parkinson's disease is a chronic progressive neurodegenerative disease of the extrapyramidal system. These symptoms are divided into specific stages based on the severity of the symptoms. Differences in Parkinson's disease severity are linked to the quality of life in Parkinson's disease patients. Demonstrate the relationship between stage and attitude quality in Parkinson's disease patients, Department of Neurology, Muhammadiyah Malang University Hospital. Thirty-seven respondents were obtained from the analytical observations using a crossover design nonrandom objective sampling method. The Hoehn and Yahr Scale for Diagnosing Parkinson's Disease Stage and Parkinson's Disease Questionnaire (PDQ-39) was used to assess the quality of the attitude process in patients with Parkinson's disease during the previous month. The Spearman Rank correction test result is 0.485, which reduces the correction between street and road quality. It is unidirectional because the correlation value is positive, so the higher the ladder, the lower the patient's quality of life. The adjustment between significant variables was 0.002 (α <0.05). This suggests that higher levels determine the quality of patient access. There is a relationship between stage and attitude quality in Parkinson's disease patients in the Department of Neurology, Muhammadiyah Malang University Hospital.

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